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Differences in MBUs induced by high-energy and medium-energy heavy ions in 28 nm FPGAs

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Nuclear Science and Techniques 2022年第9期33卷 28-36页

作者： Shuai Gao jin-Hu Yang Bing Ye Chang Cai Ze He Jie Liu Tian-Qi Liu xiao-Yu Yan You-mei Sun Guo-Qing xiao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of ASIC and System Fudan UniversityShanghai 201203China State Key Laboratory of Analog and Mixed-Signal VLSI University of MacaoMacao 999078China

Multiple-bit upsets(MBUs)have become a threat to modern advanced field-programmable gate arrays(FPGAs)applications in radiation ***,many investigations have been conducted using mediumenergy heavy ions to study the effects of MBU ***,high-energy heavy ions(HEHIs)greatly affect the size and percentage of MBUs because their ionizationtrack structures differ from those of medium-energy heavy *** this study,the different impacts of high-energy and medium-energy heavy ions on MBUs in 28 nm FPGAs as well as their mechanisms are thoroughly *** the Geant4 calculation,more serious energy effects of HEHIs on MBU scales were successfully *** addition,we identified worse MBU responses resulting from lowered *** MBU orientation effect was observed in the radiation of different *** broadened ionization tracks for tilted tests in different dimensions could result in different MBU *** results also revealed that the ionization tracks of tilted HEHIs have more severe impacts on the MBU scales than mediumenergy heavy ions with much higher linear energy ***,comprehensive radiation with HEHIs is indispensable for effective hardened designs to apply highdensity 28 nm FPGAs in deep space exploration.

关键词： FPGA High-energy heavy-ion radiation MBU Ionization track

Treating aplasia cutis congenita in a newborn with the combination of ionic silver dressing and moist exposed burn ointment: A case report

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World Journal of Clinical Cases 2019年第17期7卷 2611-2616页

作者： Guo-Feng Lei Jun-Ping Zhang xiao-Bing Wang xiao-Li You jin-Ya Gao xiao-mei Li mei-Ling Chen Xiu-Qin Ning Jiang-Li Sun Department of Neonatal Intensive Care Unit Sanmenxia Central HospitalSanmenxia 472000Henan ProvinceChina Department of Intensive Care Unit Sanmenxia Central HospitalSanmenxia 472000Henan ProvinceChina Reproductive endocrine center Sanmenxia Central HospitalSanmenxia 472000Henan ProvinceChina

BACKGROUND Aplasia cutis congenita (ACC) in newborns is a condition in which congenital defects or hypoplasia is present in part of the epidermis,dermis and even subcutaneous tissue (including muscle and bones).First reported by Cordon in 1767,ACC is a rare disease with a low incidence of 1/100000 to 3/***,there are 500 cases reported *** can be accompanied by other *** onset mechanism of the disease remains unknown but is thought to be correlated to factors such as genetics,narrow uterus,foetal skin and amniotic membrane adhesion,use of teratogenic drugs in early pregnancy and viral *** SUMMARY In August 2018,we treated a newborn with ACC on the left lower limbs using a combination of ionic silver dressing and moist exposed burn ointment (MEBO) and achieved a satisfactory treatment *** skin defects were observed on the external genitals and on areas from the left foot to 3/4 of the upper left *** tissue and blood vessels were observed in the regions with skin *** following treatments were ***,the wound was rinsed with 0.9% sodium chloride solution followed by disinfection with povidone-iodine *** then MEBO was applied to the wound at a thickness of approximately 1 *** applying ionic silver dressing,the wound was covered with sterile *** wound dressing was replaced every 2-3 *** the 4-mo follow-up,the treatment outcome was *** was minimal scar tissue formation,and limb function was not *** The combination of ionic silver dressing and MEBO to ACC is helpful.

关键词： Aplasia cutis congenita Newborns Ionic silver dressing Moist exposed burn ointment

Impact of proton pump inhibitors on clinical outcomes in patients after acute myocardial infarction: a propensity score analysis from China Acute Myocardial Infarction(CAMI) registry

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Journal of Geriatric Cardiology 2020年第11期17卷 659-665页

作者： Wen-Ce SHI Si-De GAO jin-Gang YANG xiao-Xue FAN Lin NI Shu-Hong SU mei YU Hong-mei YANG Meng-Yue YU Yue-jin YANG Department of Cardiology State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Research and Biometrics Center State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Xinxiang Central Hospital XinxiangHenan ProvinceChina Langfang People’s Hospital LangfangHebei ProvinceChina First Hospital of Qinhuangdao QinhuangdaoHebei ProvinceChina

Background Proton pump inhibitors(PPIs) are recommended by the latest guidelines to reduce the risk of bleeding in acute myocardial infarction(AMI) patients treated with dual antiplatelet therapy(DAPT). However, previous pharmacodynamic and clinical studies have reported controversial results on the interaction between PPI and the P2 Y12 inhibitor clopidogrel. We investigated the impact of PPIs use on in-hospital outcomes in AMI patients, aiming to provide a new insight on the value of PPIs. Methods A total of 23,380 consecutive AMI patients who received clopidogrel with or without PPIs in the China Acute Myocardial Infarction(CAMI) registry were analyzed. The primary endpoint was major adverse cardiovascular and cerebrovascular events(MACCE) defined as a composite of in-hospital cardiac death, re-infarction and stroke. Propensity score matching(PSM) was used to control potential baseline confounders. Multivariate logistic regression analysis was performed to evaluate the effect of PPIs use on MACCE and gastrointestinal bleeding(GIB). Results Among the whole AMI population, a large majority received DAPT and 67.5% were co-medicated with PPIs. PPIs use was associated with a decreased risk of MACCE(Before PSM OR: 0.857, 95% CI: 0.742-0.990, P = 0.0359;after PSM OR: 0.862, 95% CI: 0.768-0.949, P = 0.0245) after multivariate adjustment. Patients receiving PPIs also had a lower risk of cardiac death but a higher risk of complicating with stroke. When GIB occurred, an alleviating trend of GIB severity was observed in PPIs group. Conclusions Our study is the first nation-wide large-scale study to show evidence on PPIs use in AMI patients treated with DAPT. We found that PPIs in combination with clopidogrel was associated with decreased risk for MACCE in AMI patients, and it might have a trend to mitigate GIB severity. Therefore, PPIs could become an available choice for AMI patients during hospitalization.

关键词： Acute myocardial infarction Clopidogrel Drug interaction Propensity score

Spatial Variability of Soil Organic Carbon and Related Factors in Jiangsu Province,China

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Pedosphere 2012年第3期22卷 404-414页

作者： CHUAI xiao-Wei HUANG Xian-jin WANG Wan-jing ZHANG mei LAI Li LIAO Qi-Lin School of Geographic&Oceanographic Sciences Nanjing UniversityNanjing 210093(China) Land Development and Consolidation Technology Engineering Center of Jiangsu Province Nanjing 210093(China) Department of Urban and Resource Sciences Jinling CollegeNanjing UniversityNanjing 210093(China) jiangsu information Center Nanjing 210013(China) Geological Survey of Jiangsu Province Nanjing 210018(China)

Soil organic carbon (SOC) plays a key role in the global carbon *** this study,we used statistical and geostatistical methods to characterize and compare the spatial heterogeneity of SOC in soils of Jiangsu Province,China,and investigate the factors that influence it,such as topography,soil type,and land *** study was based on 24 186 soil samples obtained from the surface soil layer (0-0.2 m) and covering the entire area of the *** values of SOC density in the surface layer,obtained by kriging based on a spherical model,ranged between 3.25 and 32.43 kg m *** highest SOC densities tended to occur in the Taihu Plain,Lixia River Plain,along the Yangtze River,and in high-elevation hilly areas such as those in northern and southwest Jiangsu,while the lowest values were found in the coastal ***,slope,soil type,and land use type significantly affected SOC *** slope tended to result in SOC *** between elevation and SOC densities was positive in the hill areas but negative in the low plain areas,probably due to the effect of different land cover types,temperature,and soil *** SOC densities were usually found in limestone and paddy soils and low densities in coastal saline soils and alluvial soils,indicating that high clay and silt contents in the soils could lead to an increase,and high sand content to a decrease in the accumulation of *** densities were sensitive to land use and usually increased in towns,woodland,paddy land,and shallow water areas,which were strongly affected by industrial and human activities,covered with highly productive vegetation,or subject to long-term use of organic fertilizers or flooding conditions.

关键词： industrial and human activities land cover land use soil type topography

Optimization of Low Phosphorus Steel Production With Double Slag Process in BOF

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Journal of Iron and Steel Research International 2013年第8期20卷 41-47页

作者： YANG xiao SUN Feng-mei YANG jin-li LIU Fei CHENG Kui-sheng WANG Jian-hua Institute of Research of Iron and Steel (IRIS) Shasteel Hongfa Steelmaking Plant Shasteel

To produce the steel with phosphorus less than 0. 007% （mass percent）, the double slag process has been optimized in basic oxygen furnace （BOF）. Dephosphorization and decarburization are performed in sequence in the same converter. Deslagging is conducted twice, each at the end of dephosphorization and decarburization, by tilting the BOF. Production was tested in a 180 t BOF. Mass percent of phosphorus in steel at BOF blow end has been made to as low as 0. 004 2 % after optimizing operational parameters. Factors affecting dephosphorization performance were studied. Before intermediate deslagging, dephosphorization is determined by the mass transfer of phosphorus from metal/slag interface to bulk slag phase rather than equilibrium thermodynamic conditions. After intermediate deslag-ging, dephosphorization is deter/nined by the equilibriurn thermodynamic conditions such as slag composition and temperature.

关键词： dephosphorization double slag BOF

Synthesis of 12-alkoxycarbonylmethylene-1,15-pentadecanolides

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Chinese Chemical Letters 2007年第8期18卷 915-916页

作者： Jian Jun Li Shu Hui jin xiao mei Liang De Kai Yuan Dao Quan Wang Key Lab of Pesticide Chemistry and Application Technology Department of Applied Chemistry China Agricultural University Beijing 100094 China

Six novel 12-alkoxycarbonylmethylene-1,15-pentadecanolides （3） were synthesized from 2-nitrocyclo-dodecanone by the Michael addition with acrolein followed by ring enlargement, Nef reaction and Wittig-Homer reaction. Their structures were confirmed bv 1H NMR, IR and elemental analysis. The preliminary bioassay showed that they have some fungicidal activity.

关键词： 12-Alkoxycarbonylmethylene-1, 15-pentadecanolide Macrolide Acrylic ester Wittig-Horner reaction Fungicidal actictity

Features of Motion of Soliton Transported Bio-energy in Aperiodic α-Helix ProteinMolecules with Three Channels

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Communications in Theoretical Physics 2009年第1期51卷 170-180页

作者： PANG xiao-Feng LIU mei-Jie Institute of High-Energy Electronics University of Electronic Science and Technology of China Chengdu 610065 China International Center for Materials Physics Chinese Academy of Sciences Shenyang 110015 China

The structure aperiodicities can influence seriously the features of motion of soliton excited in the α-helix protein molecules with three channels. We study the influence of structure aperiodicities on the features of the soliton in the improved model by numerical simulation and Runge-Kulta method. The results obtained show that the new soliton is very robust against the structure aperiodieities including large disorder in the sequence of mass of the amino acids and fluctuations of spring constant, coupling constant, dipole-dipole interactional constant, ground state energy and chain-chain interaction. However, very strong structure aperiodieities can also destroy the stability of the soliton in the α-helix protein molecules.

关键词： structure aperiodicity soliton stability protein bio-energy Runge-Kulta method

Boundedness of fractional integral operators on α-modulation spaces

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Applied Mathematics(A Journal of Chinese Universities) 2014年第3期29卷 339-351页

作者： WU xiao-mei CHEN Jie-cheng Xingzhi Colledge Zhejiang Normal University Department of Mathematics Zhejiang Normal University

In this paper, we obtain the boundedness of the fractional integral operators, the bilineax fractional integral operators and the bilinear Hilbert transform on α-modulation spaces.

关键词： α-modulation space fractional integral operator bilinear fractional integral operator bilinearHilbert transform.

Bio-energy in s-Helix Protein Molecules with Three Properties of Soliton-Transported Channels

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Communications in Theoretical Physics 2007年第2X期48卷 369-376页

作者： PANG xiao-Feng LIU mei-Jie Institute of Life Science and Technology University of Electronic Science and Technology of China Chengdu 610054 China International Center for Material Physics the Chinese Academy of Sciences Shenyang 110015 China

We study numerically the propagating properties of soliton-transported bio-energy excited in the a-helix protein molecules with three channels in the cases of the short-time and long-time motions and its features of collision at temperature T = 0 and biological temperature T = 300 K by the dynamic equations in the improved Davydov theory and fourth-order Runge-Kutta method, respectively. From these simulation experiments we see that the new solitons in the improved model can move without dispersion at a constant speed retaining its shape and energy in the cases of motion of both short-time or T = 0 and long time or T = 300 K and can go through each other without scattering in their collisions. In these cases its lifetime is, at least, 120 ps at 300 K, in which the soliton can travel over about 700 amino acid residues. This result is consistent with analytic result obtained by quantum perturbed theory in this model. In the meanwhile, the influences of structure disorder of a-helix protein molecules, including the inhomogeneous distribution of amino acids with different masses and fluctuations of spring constant, dipole-dipole interaction, exciton-phonon coupling constant and diagonal disorder, on the solitons are also studied by the fourth-order Runge-Kutta method. The results show that the soliton still is very robust against the structure disorders and thermal perturbation of proteins at biological temperature 300 K. Therefore we can conclude that the new soliton in the a-helix protein molecules with three channels is a possible carrier of bio-energy transport and the improved model is possibly a candidate for the mechanism of this transport.

关键词： bio-energy transport soliton protein molecule Runge-Kutta method thermal stabilization