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China Foundry 2019年第4期16卷 238-247页

作者： Xiong Yang Yuan-dong Li xiao-mei luo Hong-wei Zhou Qi-yong Cai Ming Li Ying Ma State Key Laboratory ofAdvanced Processing and Recycling of Non-ferrous Metals Lanzhou University of Technology Lanzhou 730050 China Key Lab of Non-ferrous Metal Alloys and Processing Ministry of Education Lanzhou University of Technology L anzhou 730050 China

In the present work, 7075 aluminum alloy(Al-Zn-Mg-Cu) was produced by both conventional casting(CC) and controlled diffusion solidification(CDS) methods. Each sample was subjected to different heat-treatment conditions: as-cast, T4, and T6;and their microstructural and mechanical properties were investigated by optical microscopy(OM), scanning electron microscopy(SEM) and X-ray diffractometry(XRD). It was found that CDS promoted the formation of non-dendritic primary α-Al phase and reduced shrinkage porosity, thus resulting in improved mechanical properties. In addition, the eutectic phase of the CDS samples mainly consisted of T(Al-ZnMg-Cu) phase, which manifested a well-developed lamellar eutectic structure. However, in the CC samples, the T(Al-Zn-Mg-Cu) phase was composed of rod-like eutectics. Moreover, the θ(Al2 Cu) eutectic contents in the CC samples were greater than those in the CDS samples. Each element in the CC samples had an obvious change in the grain boundary, whereas the change in element content in the CDS samples was gradual. Therefore, the non-dendritic morphology of the primary phase and the presence of rod-like eutectics in the matrix of the CDS samples led to enhanced tensile strength and elongation under different heat treatment conditions.

关键词： primary α-Al phase eutectic phase solute atoms tensile strength elongation

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Effect of Zn, Cu and Ni addition on microstructure and mechanical properties of ascast Mg-Dy alloys

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China Foundry 2016年第1期13卷 54-58页

作者： Guang-li Bi xiao-mei luo Jing Jiang Yong-gang Zhang Jian-ji Xu Jie-ming Chen Yuan-dong Li Ying Ma State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of Technology Key Laboratory of Nonferrous Metal alloys and Processing Ministry of Education Lanzhou University of Technology

This paper presents some research information on the effects of Zn, Cu and Ni on the microstructure and mechanical properties of as-cast Mg-2Dy(at.%) alloys. The Mg-2Dy alloy is composed of α-Mg and Mg24Dy5 phases. With the addition of 0.5at.%Zn, 0.5at.%Cu and 0.5at.%Ni, respectively, besides α-Mg, the long period stacking order(LPSO) phases containing Zn, Cu, and Ni precipitated in the α-Mg interdentritic boundary. The addition of Ni effectively refined the dendrite arm spacing. The as-cast Mg-2Dy-0.5Ni alloy exhibited the best tensile strengths and elongation. The better mechanical properties were mainly attributed to small secondry dendrite arm spacing(SDAS) and high volume fraction of LPSO phases.

关键词： Mg-Dy-Zn(Cu,Ni) alloys LPSO phase microstructure mechanical properties

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Adrenocorticotropic hormone combined with magnesium sulfate therapy for infantile epileptic spasms syndrome:a real-world study

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World Journal of Pediatrics 2024年第8期20卷 834-847页

作者： Wen He Qiu-Hong Wang Jiu-Wei Li Yang-Yang Wang xiao-mei luo Lin Wan Jing Wang Xiu-Yu Shi Wei-Hua Zhang Fang Fang Li-Ping Zou Senior Department of Pediatrics the Seventh Medical Center of Chinese PLA General HospitalDepartment of Pediatricsthe First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Neurology Beijing Children’s HospitalCapital Medical UniversityBeijingChina Center of Epilepsy Beijing Institute for Brain DisordersBeijing 100069China

Background Infantile epileptic spasms syndrome(IESS)is a serious disease in infants,and it usually evolves to other epilepsy types or syndromes,especially refractory or super-refractory focal *** adrenocorticotropic hormone(ACTH)is one of the first-line and effective treatment plans for IESS,it has serious side effects and is not sufficiently *** A retrospective study of the clinical outcomes of ACTH combined with magnesium sulfate(MgSO_(4))therapy for IESS in two hospital centers was *** major outcome of the single and combined treatment was evaluated by changes in seizure frequency and improvements in hypsarrhythmia electroencephalography(EEG).To reduce the confounding bias between the two groups,we used SPSS for the propensity score matching(PSM)*** We initially recruited 1205 IESS patients from two Chinese hospitals and treated them with ACTH combined with MgSO_(4) and ACTH *** 1005 patients were enrolled in the treatment(ACTH combined with MgSO_(4):744,ACTH:261),and both treatment plans had a more than 55% response ***,compared to patients treated with ACTH alone,those patients treated with ACTH combined with MgSO_(4) had better performance in terms of the seizure frequency and hypsarrhythmia *** PSM,the two groups also showed significant differences in responder rate[70.8%(95% confidence interval,CI)=66.7%–74.8%)vs.53.8%(95%CI=47.4%–60.2%),P3 months(P<0.05).In addition,the overall incidence of adverse reactions in the ACTH combined with MgSO_(4) group was much lower than that in the ACTH group(31.4%vs.63.1%,P<0.001).During th

关键词： Adrenocorticotropic hormone Clinical trial Infantile epileptic spasms syndrome Magnesium sulfate Real-world study

Advances in cryoablation for pancreatic cancer

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World Journal of Gastroenterology 2016年第2期22卷 790-800页

作者： xiao-mei luo Li-Zhi Niu Ji-Bing Chen Ke-Cheng Xu Medical College Jinan University Guangzhou Fuda Cancer Hospital School of Medicine Jinan University

Pancreatic carcinoma is a common cancer of the digestive system with a poor prognosis. It is characterized by insidious onset, rapid progression, a high degree of malignancy and early metastasis. Atpresent, radical surgery is considered the only curative option for treatment, however, the majority of patients with pancreatic cancer are diagnosed too late to undergo surgery. The sensitivity of pancreatic cancer to chemotherapy or radiotherapy is also poor. As a result, there is no standard treatment for patients with advanced pancreatic cancer. Cryoablation is generally considered to be an effective palliative treatment for pancreatic cancer. It has the advantages of minimal invasion and improved targeting, and is potentially safe with less pain to the patients. It is especially suitable in patients with unresectable pancreatic cancer. However, our initial findings suggest that cryotherapy combined with 125-iodine seed implantation, immunotherapy or various other treatments for advanced pancreatic cancer can improve survival in patients with unresectable or metastatic pancreatic cancer. Although these findings require further in-depth study, the initial results are encouraging. This paper reviews the safety and efficacy of cryoablation, including combined approaches, in the treatment of pancreatic cancer.

关键词： Pancreatic cancer Cryoablation Combinationtherapy Cryoimmunotherapy

Influencing factors of early post-traumatic stress disorder in young and middle-aged individuals with open globe injuries in west China:a cross-sectional study

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International Journal of Ophthalmology(English edition) 2025年第1期18卷 146-153页

作者： Yi-Man Li Xin Zhang Ji-Hong Zeng Hong-mei luo Department of Ophthalmology West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

AIM:To evaluate the prevalence of early post-traumatic stress disorder(PTSD)among young and middle-aged patients who have suffered open globe injuries,and to identify the psychosocial factors influencing PTSD in these ***:A total of 280 patients who underwent ocular trauma surgery between January 2023 and January 2024 were selected through convenience *** were collected using a custom-designed demographic questionnaire,the Connor-Davidson Resilience Scale(CDRISC),the Cognitive Emotion Regulation Questionnaire(C-ERRI),and the PTSD Checklist-Civilian Version(PCL-C).Univariate analysis and stepwise multiple linear regression analysis were performed to determine the factors affecting PTSD in these ***:The average PTSD score for the patients was 33.22±*** scores for individual PTSD dimensions,ranked from highest to lowest,were recurrent traumatic experiences,heightened arousal,avoidance reactions,and social *** PTSD symptoms were observed in 85 patients(30.36%).Univariate analysis indicated that gender,postoperative vision,marital status,psychological resilience,and rumination were significant factors affecting PTSD symptoms(χ^(2)/t=6.53,17.88,8.83,2.17,and 14.1,respectively;all P<0.05).Pearson correlation analysis showed a positive correlation between rumination and PTSD symptoms(r=0.73,P<0.01)and a negative correlation between psychological resilience and PTSD symptoms(r=-0.14,P<0.05).Stepwise multiple linear regression analysis identified postoperative vision(notably eye removal),rumination levels,and psychological resilience(optimism)as major factors influencing PTSD in these patients(R^(2)=0.57,P<0.001).CONCLUSION:Young and middle-aged patients with open globe injuries have a high incidence of *** risk factors for early PTSD include primary enucleation,high levels of rumination,and low psychological resilience(optimism).Conversely,patients with good postoperative vision recovery,low rumination l

关键词： young and middle-aged open globe injuries post-traumatic stress disorder rumination psychological resilience

Retrospective analysis of pathological types and imaging features in pancreatic cancer: A comprehensive study

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 121-129页

作者： Yang-Gang luo mei Wu Hong-Guang Chen Pathology Department Xuanhan County People’s HospitalDazhou 636150Sichuan ProvinceChina

BACKGROUND Pancreatic cancer remains one of the most lethal malignancies worldwide,with a poor prognosis often attributed to late *** the correlation between pathological type and imaging features is crucial for early detection and appropriate treatment *** To retrospectively analyze the relationship between different pathological types of pancreatic cancer and their corresponding imaging *** We retrospectively analyzed the data of 500 patients diagnosed with pancreatic cancer between January 2010 and December 2020 at our *** types were determined by histopathological examination of the surgical spe-cimens or biopsy *** imaging features were assessed using computed tomography,magnetic resonance imaging,and endoscopic *** analyses were performed to identify significant associations between pathological types and specific imaging *** There were 320(64%)cases of pancreatic ductal adenocarcinoma,75(15%)of intraductal papillary mucinous neoplasms,50(10%)of neuroendocrine tumors,and 55(11%)of other rare *** imaging features were identified in each pathological *** ductal adenocarcinoma typically presents as a hypodense mass with poorly defined borders on computed tomography,whereas intraductal papillary mucinous neoplasms present as characteristic cystic lesions with mural *** tumors often appear as hypervascular lesions in contrast-enhanced *** analysis revealed significant correlations between specific imaging features and pathological types(P<0.001).CONCLUSION This study demonstrated a strong association between the pathological types of pancreatic cancer and imaging *** findings can enhance the accuracy of noninvasive diagnosis and guide personalized treatment approaches.

关键词： Pancreatic cancer Pathological types Imaging features Retrospective analysis Diagnostic accuracy

Prevalence of Helicobacter pylori infection in Chinese military personnel:A cross-sectional,multicenter-based study

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World Journal of Gastroenterology 2025年第3期31卷 42-49页

作者： Han-Chen Min Chun-Yan Zhang Fang-Yu Wang xiao-Hui Yu Shan-Hong Tang Hong-Wu Zhu Ya-Gang Zhao Ji-luo Liu Jian Wang Jing-Han Guo xiao-mei Zhang Yun-Sheng Yang Chinese People’s Liberation Army Medical School Chinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology and Hepatology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Sixth Healthcare Department The Second Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation ArmyLanzhou 730050Gansu ProvinceChina Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610011Sichuan ProvinceChina Department of Gastroenterology General Hospital of Southern Theater CommandGuangzhou 510010Guangdong ProvinceChina Department of Epidemiology Naval Medical UniversityShanghai 200433China School of Medicine Nankai UniversityTianjin 300071China National Clinical Research Center for Geriatric Diseases Chinese People’s Liberation Army General HospitalBeijing 100853China

BACKGROUND Helicobacter pylori(***)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military *** guidelines in China state all patients with evidence of active infection with *** are offered ***,the prevalence of *** infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment *** the prevalence of *** infection in the military population will aid in the development of customized strategies to better manage this infectious *** To investigate the prevalence of *** infection in the Chinese military population in different geographic *** This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of *** infection was identified using the urea breath test,which had been performed between January 2020 and December *** Of the 22421 military service members,7416(33.1%)were urea breath *** highest prevalence of *** was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected *** individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,*** *** infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.

关键词： Helicobacter pylori Prevalence Military personnel Urea breath test Multicenter study

Comparasion of Inhibitory Effects on Survivin Gene Expression in Prostate Cancer by Vector-based microRNA and siRNA

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Comparasion of Inhibitory Effects on Survivin Gene Expressio...

Efficacy and safety of JAK inhibitors in connective tissue disease-associated interstitial lung disease

2008年全国生物化学与分子生物学学术大会

作者： Jia-yun Liu xiao-mei luo Ming-quan Su xiao-ke Hao (Center for Clinical Laboratory Medicine of PLA,Xijing Hospital,Fourth Military Medical Universty,Xian 710032,China)

Small interfering RNA (siRNA) and microRNA (miRNA) are small RNAs that play important roles in regu- lating gene *** serve as guides for silencing their corresponding target mRNAs and the promise of

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中华医学杂志(英文版) 2025年第1期138卷 1-4页

作者： Wu Jiajia mei Chunli luo Zhijun Yuan Xujing Lin Wenxun Du Rong Department of Rheumatology and Immunology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China

Calibration of the Solar X-ray Detector on-board the Macao Science Satellite-1B for Soft X-ray Detection

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Science China Earth Sciences 2025年第1期68卷 11-26页

作者： Man-Hei NG xiaoping ZHANG Jianwu CHEN Yongqiang SHI Fuchang ZUO Wenxi PENG Weichun FU Liansheng LI Pengwei luo Chi-Long TANG Guozheng ZHANG Zhiwu mei Li WANG Cunhui LI Jiaming OU Yanyan Xu State Key Laboratory of Lunar and Planetary Sciences Macao University of Science and TechnologyMacao999078China Space Optoelectronic Measurement and Perception Laboratory Beijing Institute of Control EngineeringBeijing100190China Institute of High Energy Physics Chinese Academy of SciencesBeijing100049China Science and Technology on Vacuum Technology and Physics Laboratory Lanzhou Institute of PhysicsLanzhou730000China China National Space Administration(CNSA) Macao Center for Space Exploration and ScienceMacao999078China

The Solar X-ray Detector(SXD)on-board the Macao Science Satellite-1B(MSS-1B)was successfully launched via the Chinese Long March-2C rocket on 21 May 2023,and commenced operations in early June of the same *** MSS-1B/Soft X-ray Detection Units(SXDUs)employ two silicon drift detectors(SDDs),providing a wide range of energy spectra spanning from 0.7 to 24 ***,the SXDUs deliver a high-resolution capability of 0.14 keV@5.9 keV and operate with a time cadence of 1 ***,we perform thorough calibrations of the MSS-1B/SXDUs,employing a combination of ground experiments and *** addition,quantitative analysis comparing the flux measurements obtained by the MSS-1B/SXDUs to the data collected by the Geostationary Operational Environmental Satellite(GOES),provides compelling evidence of their ***,the preliminary spectral analysis results showcase the robustness and expected performance of the MSS-1B/SXDUs,unlocking their potential for facilitating the study of dynamic evolution of solar ***,the innovative MSS-1B/Solar X-ray Detector facilitates concurrent observations of solar soft and hard X-rays,thereby making valuable contributions to the advancements in solar research.

关键词： Macao Science Satellite-1B(MSS-1B) Calibration Solar X-Ray Detector Spectrometer Soft X-rays Solar flares Solar abundances

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