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China Foundry 2019年第4期16卷 238-247页

作者： Xiong Yang Yuan-dong Li xiao-mei luo Hong-wei Zhou Qi-yong Cai Ming Li Ying Ma State Key Laboratory ofAdvanced Processing and Recycling of Non-ferrous Metals Lanzhou University of Technology Lanzhou 730050 China Key Lab of Non-ferrous Metal Alloys and Processing Ministry of Education Lanzhou University of Technology L anzhou 730050 China

In the present work, 7075 aluminum alloy(Al-Zn-Mg-Cu) was produced by both conventional casting(CC) and controlled diffusion solidification(CDS) methods. Each sample was subjected to different heat-treatment conditions: as-cast, T4, and T6;and their microstructural and mechanical properties were investigated by optical microscopy(OM), scanning electron microscopy(SEM) and X-ray diffractometry(XRD). It was found that CDS promoted the formation of non-dendritic primary α-Al phase and reduced shrinkage porosity, thus resulting in improved mechanical properties. In addition, the eutectic phase of the CDS samples mainly consisted of T(Al-ZnMg-Cu) phase, which manifested a well-developed lamellar eutectic structure. However, in the CC samples, the T(Al-Zn-Mg-Cu) phase was composed of rod-like eutectics. Moreover, the θ(Al2 Cu) eutectic contents in the CC samples were greater than those in the CDS samples. Each element in the CC samples had an obvious change in the grain boundary, whereas the change in element content in the CDS samples was gradual. Therefore, the non-dendritic morphology of the primary phase and the presence of rod-like eutectics in the matrix of the CDS samples led to enhanced tensile strength and elongation under different heat treatment conditions.

关键词： primary α-Al phase eutectic phase solute atoms tensile strength elongation

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Effect of Zn, Cu and Ni addition on microstructure and mechanical properties of ascast Mg-Dy alloys

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China Foundry 2016年第1期13卷 54-58页

作者： Guang-li Bi xiao-mei luo Jing Jiang Yong-gang Zhang Jian-ji Xu Jie-ming Chen Yuan-dong Li Ying Ma State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of Technology Key Laboratory of Nonferrous Metal alloys and Processing Ministry of Education Lanzhou University of Technology

This paper presents some research information on the effects of Zn, Cu and Ni on the microstructure and mechanical properties of as-cast Mg-2Dy(at.%) alloys. The Mg-2Dy alloy is composed of α-Mg and Mg24Dy5 phases. With the addition of 0.5at.%Zn, 0.5at.%Cu and 0.5at.%Ni, respectively, besides α-Mg, the long period stacking order(LPSO) phases containing Zn, Cu, and Ni precipitated in the α-Mg interdentritic boundary. The addition of Ni effectively refined the dendrite arm spacing. The as-cast Mg-2Dy-0.5Ni alloy exhibited the best tensile strengths and elongation. The better mechanical properties were mainly attributed to small secondry dendrite arm spacing(SDAS) and high volume fraction of LPSO phases.

关键词： Mg-Dy-Zn(Cu,Ni) alloys LPSO phase microstructure mechanical properties

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Adrenocorticotropic hormone combined with magnesium sulfate therapy for infantile epileptic spasms syndrome:a real-world study

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World Journal of Pediatrics 2024年第8期20卷 834-847页

作者： Wen He Qiu-Hong Wang Jiu-Wei Li Yang-Yang Wang xiao-mei luo Lin Wan Jing Wang Xiu-Yu Shi Wei-Hua Zhang Fang Fang Li-Ping Zou Senior Department of Pediatrics the Seventh Medical Center of Chinese PLA General HospitalDepartment of Pediatricsthe First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Neurology Beijing Children’s HospitalCapital Medical UniversityBeijingChina Center of Epilepsy Beijing Institute for Brain DisordersBeijing 100069China

Background Infantile epileptic spasms syndrome(IESS)is a serious disease in infants,and it usually evolves to other epilepsy types or syndromes,especially refractory or super-refractory focal *** adrenocorticotropic hormone(ACTH)is one of the first-line and effective treatment plans for IESS,it has serious side effects and is not sufficiently *** A retrospective study of the clinical outcomes of ACTH combined with magnesium sulfate(MgSO_(4))therapy for IESS in two hospital centers was *** major outcome of the single and combined treatment was evaluated by changes in seizure frequency and improvements in hypsarrhythmia electroencephalography(EEG).To reduce the confounding bias between the two groups,we used SPSS for the propensity score matching(PSM)*** We initially recruited 1205 IESS patients from two Chinese hospitals and treated them with ACTH combined with MgSO_(4) and ACTH *** 1005 patients were enrolled in the treatment(ACTH combined with MgSO_(4):744,ACTH:261),and both treatment plans had a more than 55% response ***,compared to patients treated with ACTH alone,those patients treated with ACTH combined with MgSO_(4) had better performance in terms of the seizure frequency and hypsarrhythmia *** PSM,the two groups also showed significant differences in responder rate[70.8%(95% confidence interval,CI)=66.7%–74.8%)vs.53.8%(95%CI=47.4%–60.2%),P3 months(P<0.05).In addition,the overall incidence of adverse reactions in the ACTH combined with MgSO_(4) group was much lower than that in the ACTH group(31.4%vs.63.1%,P<0.001).During th

关键词： Adrenocorticotropic hormone Clinical trial Infantile epileptic spasms syndrome Magnesium sulfate Real-world study

Advances in cryoablation for pancreatic cancer

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World Journal of Gastroenterology 2016年第2期22卷 790-800页

作者： xiao-mei luo Li-Zhi Niu Ji-Bing Chen Ke-Cheng Xu Medical College Jinan University Guangzhou Fuda Cancer Hospital School of Medicine Jinan University

Pancreatic carcinoma is a common cancer of the digestive system with a poor prognosis. It is characterized by insidious onset, rapid progression, a high degree of malignancy and early metastasis. Atpresent, radical surgery is considered the only curative option for treatment, however, the majority of patients with pancreatic cancer are diagnosed too late to undergo surgery. The sensitivity of pancreatic cancer to chemotherapy or radiotherapy is also poor. As a result, there is no standard treatment for patients with advanced pancreatic cancer. Cryoablation is generally considered to be an effective palliative treatment for pancreatic cancer. It has the advantages of minimal invasion and improved targeting, and is potentially safe with less pain to the patients. It is especially suitable in patients with unresectable pancreatic cancer. However, our initial findings suggest that cryotherapy combined with 125-iodine seed implantation, immunotherapy or various other treatments for advanced pancreatic cancer can improve survival in patients with unresectable or metastatic pancreatic cancer. Although these findings require further in-depth study, the initial results are encouraging. This paper reviews the safety and efficacy of cryoablation, including combined approaches, in the treatment of pancreatic cancer.

关键词： Pancreatic cancer Cryoablation Combinationtherapy Cryoimmunotherapy

Synergistically enhanced ORR and HER performance on Co-N-C coupled in-situ generated PtCo intermetallic

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Journal of Energy Chemistry 2025年第1期100卷 721-729页

作者： Guanyu luo Min Song Lulu An xiao Huang Qian Zhang Chenhao Zhang Tao Shen Shuang Wang Deli Wang Key Laboratory of Material Chemistry for Energy Conversion and Storage (Huazhong University of Science and Technology) Ministry of Education School of Chemistry and Chemical Engineering Huazhong University of Science and Technology

Integrating multi-scale sites in a composite catalyst is vital to realize efficient ***,a synergistic composite catalyst consisting of Co atomic sites and in-situ generated PtCo intermetallic compounds （IMCs）(o-PtCo@CoNC) is proposed through Co pre-anchoring and subsequent impregnation-reduction *** loading of Co atoms provides a chance for in-situ generating PtCo ordered intermetallic *** remaining Co single atoms and PtCo IMCs construct synergistic electrocatalytic *** from the ordered structure,synergistic effect of Pt Co IMCs and Co single atoms,o-PtCo@CoNC exhibits excellent electrocatalytic performance for oxygen reduction reaction （ORR） and hydrogen evolution reaction （HER） with mass activity of 1.21 A mgPt-1（at 0.9 V） and5.70 A mgPt-1（at an overpotential of 100 mV）,***,o-PtCo@CoNC delivers negligible loss of half-wave potential and overpotential during long-term stability test in acid solutions,with 13 mV decay after 50,000 potential cycles for ORR and a 2.7 mV decay after 20,000 potential cycles for *** integration strategy of single-atomic sites coupled IMCs paves the way for enhancing the activity and durability of Pt-based electrocatalysts.

关键词： Synergistic effect Intermetallics Single atomic sites Oxygen reduction reaction Hydrogen evolution reaction

Comparasion of Inhibitory Effects on Survivin Gene Expression in Prostate Cancer by Vector-based microRNA and siRNA

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Comparasion of Inhibitory Effects on Survivin Gene Expressio...

Modular assembly of complex C-alkyl glycoside enabled via cooperative NHC and photoredox catalysis

2008年全国生物化学与分子生物学学术大会

作者： Jia-yun Liu xiao-mei luo Ming-quan Su xiao-ke Hao (Center for Clinical Laboratory Medicine of PLA,Xijing Hospital,Fourth Military Medical Universty,Xian 710032,China)

Small interfering RNA (siRNA) and microRNA (miRNA) are small RNAs that play important roles in regu- lating gene *** serve as guides for silencing their corresponding target mRNAs and the promise of

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Science China Chemistry 2025年

作者： Rui-Qiang Jiao Ming Li Xi Chen mei-Ze Xu Tian Ding xiao-Ping Gong Zhuo-mei Li Xue-Yuan Liu Yong-Min Liang State Key Laboratory of Applied Organic Chemistry Lanzhou University College of Chemistry and Chemical Engineering Northwest Normal University

C-Alkyl glycosides are found in natural products and are indispensable in drug development programs,owing to their diverse range of medicinal ***-component reactions involving glycosyl radical addition are well documented and proved efficient for the C-alkyl glycosides ***,multicomponent reactions for the rapid and controllable construction of structurally diversified C-alkyl glycosides in a single step remains a significant challenge due to the issues associated with balancing reactivity,compatibility,and ***,we report an NHC and photoredox co-catalyzed three-component method to access complex and valuable C-alkyl *** protocol exhibits broad substrate scope and excellent chemoand ***,nine types of sugars are compatible with this *** addition,the generality of this catalytic strategy was further highlighted by the potential for scalable production,the feasibility of further modifications of the products and its successful application in the late-stage functionalization of pharmaceutical skeletons.

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Compressive anisotropy of extruded Mg-Dy-Zn alloy sheet

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Transactions of Nonferrous Metals Society of China 2016年第2期26卷 390-397页

作者：罗晓梅毕广利姜静李明李荣广李元东马颖郝远兰州理工大学省部共建有色金属先进加工与再利用国家重点实验室兰州730050 兰州理工大学有色金属合金及加工教育部重点实验室兰州730050 沈阳化工大学机械工程学院沈阳110142

Compressive anisotropy of extruded Mg-2Dy-0.5Zn （mole fraction, %） alloy sheet was investigated. The alloy sheet was mainly composed ofα-Mg, （Mg, Zn）xDy phase and a large number of long period stacking ordered （LPSO） phases distributed along the extrusion direction. The compressive experimental results show that the alloy sheet exhibits an obvious compressive anisotropy. The compressive strength of the specimen in the extrusion direction （ED） is higher than those of the specimens in the transverse direction （TD） and 45° inclined to the extrusion direction. The compressive yield strength （CYS）, ultimate compressive strength （UCS） and compressive strain of the specimen in the ED are 274.65 MPa, 518.94 MPa and 12.93%, respectively. The compressive anisotropy is mainly attributed to the distribution of LPSO phase and formation of〈10 10〉//ED fiber texture in the deformed grains.

关键词： Mg-Dy-Zn alloy microstructure texture LPSO phase compressive anisotropy

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非静水压作用下石膏电学性质的理论研究

原子与分子物理学报 2025年第6期42卷 129-135页

作者：周梅吴雷罗小松何宗润贵州民族大学物理与机电工程学院贵阳550025 重庆大学能源与动力工程学院重庆400044

地球内部广泛存在着差应力,这些外在因素的存在影响着矿物的性质,而矿物的电学性质与结构相变息息相关.为了更加了解地球内部结构与动力学过程,采用第一性原理方法,在等效平衡压0~10 GPa范围内计算地球内部浅层矿物石膏在静水压和非静... 详细信息

地球内部广泛存在着差应力,这些外在因素的存在影响着矿物的性质,而矿物的电学性质与结构相变息息相关.为了更加了解地球内部结构与动力学过程,采用第一性原理方法,在等效平衡压0~10 GPa范围内计算地球内部浅层矿物石膏在静水压和非静水压条件下的电学性质.计算结果表明:静水压和非静水压条件下无水石膏的密度和带隙变化基本一致,但二水石膏的密度和带隙在非静水压为6 GPa附近发生突变,这可能是由于非静水压环境使晶体结构更容易发生畸变,更有利于水分子氢键网络的重新排列和CaSO_(4)层间结构的塌缩,因此非静水压下可能更加有利于二水石膏在高温高压下的脱水反应.这对理解地幔中矿物的脱水和储水产生重大的影响,为理解地幔中矿物的脱氢和储水提供理论依据.

关键词：差应力石膏电学性质第一性原理

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Ag+-NH3-NS（亚氨基二磺酸盐）体系中的放电络离子

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西南师范学院学报(自然科学版) 1983年第1期 89-97页

作者：郑筱梅罗维忠曹克复西南师范学院化学系

本文用循环伏安法研究Ag+—NH3—NS双络合剂体系及相应的单络合剂体系的放电络离子,并用时间电位法测定了放电反应的iτ1/2—i关系。结果表明:在双络合剂体系中放电的是溶液中主要存在的复合络离子,此放电反应没有前置转化步骤存在,是... 详细信息

本文用循环伏安法研究Ag+—NH3—NS双络合剂体系及相应的单络合剂体系的放电络离子,并用时间电位法测定了放电反应的iτ1/2—i关系。结果表明:在双络合剂体系中放电的是溶液中主要存在的复合络离子,此放电反应没有前置转化步骤存在,是复合络离子直接放电,当放电离子是[Ag（NH3）2NS]时阴极析出银的电化学极化最大。

关键词：络离子反应双络合剂 NH3-NS Ag NS 亚氨基磺酸盐酸衍生物