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Robust twin-field quantum key distribution through sending or not sending

National Science Review 2023年第4期10卷 76-85页

作者： Cong Jiang Zong-Wen Yu xiao-long hu Xiang-Bin Wang Jinan Institute of Quantum Technology State Key Laboratory of Low Dimensional Quantum Physics Department of Physics Tsinghua University Data Communication Science and Technology Research Institute School of Physics State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen University Shanghai Branch CAS Center for Excellence and Synergetic Innovation Center in Quantum Information and Quantum Physics University of Science and Technology of China Shenzhen Institute for Quantum Science and Engineering and Physics Department Southern University of Science and Technology Frontier Science Center for Quantum Information

The sending-or-not-sending(SNS) protocol is one of the most major variants of the twin-field(TF)quantum key distribution(QKD) protocol and has been realized in a 511-km field fiber, the farthest field experiment to date. In practice, however, all decoy-state methods have unavoidable source errors, and the source errors may be non-random, which compromises the security condition of the existing TF-QKD protocols. In this study, we present a general approach for efficiently calculating the SNS protocol’s secure key rate with source errors, by establishing the equivalent protocols through virtual atenuation and the tagged model. This makes the first result for TF QKD in practice where source intensity cannot be controlled exactly. Our method can be combined with the two-way classical communication method such as active odd-parity pairing to further improve the key rate. The numerical results show that if the intensity error is within a few percent, the key rate and secure distance only decrease marginally. The key rate of the recent SNS experiment in the 511-km field fiber is still positive using our method presented here, even if there is a ±9.5% intensity fluctuation. This shows that the SNS protocol is robust against source errors.

关键词： quantum information quantum key distribution sending or not sending twin field source error

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Immobilization of foreign protein into polyhedra of Bombyx mori nucleopolyhedrovirus(BmNPV)

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第2期13卷 111-117页

作者： Xing-wei XIANG Rui YANG Lin CHEN xiao-long hu Shao-fang YU Cui-ping CAO xiao-feng WU College of Animal Sciences Zhejiang UniversityHangzhou 310058China

In the late phase of Bombyx mori nucleopolyhedrovirus(BmNPV)infection,a large amount of polyhedra appear in the infected cell nucleolus,these polyhedra being dense protein crystals protecting the incorporated virions from the harsh *** investigate whether the foreign protein could be immobilized into the polyhedra of BmNPV,two recombinant baculoviruses were generated by a novel BmNPV polyhedrin-plus(polh +)Bac-to-Bac system,designated as vBmBac(polh +)-enhanced green fluorescent protein(EGFP)and vBmBac(polh +)-LacZ,which can express the polyhedrin and foreign protein *** microscopy analysis showed that all viruses produced polyhedra of normal *** fluorescence can be apparently detected on the surface of the vBmBac(polh +)-EGFP polyhedra,but not the BmNPV *** analysis and anti-desiccation testing confirmed that EGFP was embedded in the *** expected,the vBmBac(polh +)-LacZ polyhedra contained an amount of LacZ and had a higherβ-galactosidase *** dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE)and Western blotting were also performed to verify if the foreign proteins were immobilized into *** study provides a new inspiration for efficient preservation of useful proteins and development of new pesticides with toxic proteins.

关键词： Bombyx mori nucleopolyhedrovirus Polyhedra Foreign protein Protein immobilization

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Expression analysis of chlorophyllid a binding protein a secretory, red fluorescence protein in the midgut of silkworm, Bombyx mori

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Insect Science 2014年第1期21卷 20-30页

作者： Lin Chen Rui Yang xiao-long hu Xing-Wei Xiang xiao-Feng Wu Institute of Sericulture and Apiculture College of Animal Sciences Zhejiang University Hangzhou China

Chlorophyllid a binding protein （ chbp） was recently characterized by its ability to bind the prosthetic group of chlorophylls and little information is known regarding its expression. In the present study, we found that chpb was expressed highly and exclusively in the midgut of silkworm, Bombyx mori. The expression level of chbp was very high in the newly molted fifth instar larvae followed by gradual decline in the same instar. Our results demonstrated that CHBP was a secretory protein and located mainly in the apical of midgut epithelial cells. Real-time polymerase chain reaction analysis results showed that chpb highly expressed in the anterior midgut, threefold and sixfold higher compared with that of the middle midgut and posterior midgut, respectively, and chpb expression declined in darkness. In addition, the expression of chbp was affected by high-dose virus or bacterium infection.

关键词： Bombyx mori chlorophyllid binding protein expression midgut

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Measurement-device-independent quantum key distribution protocol with phase post-selection

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Photonics Research 2022年第7期10卷 1703-1711页

作者： CONG JIANG xiao-long hu ZONG-WEN YU XIANG-BIN WANG Jinan Institute of Quantum Technology Jinan 250101China State Key Laboratory of Low Dimensional Quantum Physics Department of PhysicsTsinghua UniversityBeijing 100084China School of Physics State Key Laboratory of Optoelectronic Materials and TechnologiesSun Yat-sen UniversityGuangzhou 510275China Data Communication Science and Technology Research Institute Beijing 100191China Shanghai Branch CAS Center for Excellence and Synergetic Innovation Center in Quantum Information and Quantum PhysicsUniversity of Science and Technology of ChinaShanghai 201315China Shenzhen Institute for Quantum Science and Engineering and Physics DepartmentSouthern University of Science and TechnologyShenzhen 518055China Frontier Science Center for Quantum Information BeijingChina

Measurement-device-independent quantum key distribution(MDI-QKD)protocol can remove all the loopholes of the detection devices and,thus,has attracted much *** on the technique of single-photon interference,we propose a modified MDI-QKD protocol with phase *** prove the security of the announcement of the private phases in the X basis and show how to apply the phase post-selection method to the double-scanning four-intensity MDI-QKD *** numerical results show that the phase postselection method can significantly improve the key rates at all *** the double-scanning method,two parameters need to be scanned in the calculation of the final key rate,and the global parameter optimization is pretty *** propose an accelerated method that can greatly reduce the running time of the global parameter optimization *** makes the method practically useful in an unstable channel.

关键词： distribution phase quantum

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Efficacy and safety of targeted therapy plus immunotherapy combined with hepatic artery infusion chemotherapy (FOLFOX) for unresectable hepatocarcinoma

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World Journal of Gastroenterology 2024年第17期30卷 2321-2331页

作者： Zhi-Peng Lin xiao-long hu Du Chen Da-Bei huang Xu-Gong Zou Hai Zhong Sheng-Xiang Xu Yuan Chen xiao-Qun Li Jian Zhang Department of Interventional Medicine Zhongshan People’s HospitalZhongshan 528400Guangdong ProvinceChina

BACKGROUND The advent of cutting-edge systemic therapies has driven advances in the treatment of hepatocellular carcinoma(HCC),and therapeutic strategies with multiple modes of delivery have been shown to be more efficacious than ***,the mechanisms underlying this innovative treatment modality have not been *** To evaluate the clinical efficacy of targeted therapy plus immunotherapy combined with hepatic arterial infusion chemotherapy(HAIC)of FOLFOX in patients with unresectable *** We enrolled 53 patients with unresectable HCC who received a combination of targeted therapy,immunotherapy,and HAIC of FOLFOX between December 2020 and June 2021 and assessed the efficacy and safety of the treatment *** The objective response rate was 60.4%(32/53),complete response was 24.5%(13/53),partial response was 35.9%(19/53),and stable disease was 39.6%(21/53).The median duration of response and median progression-free survival were 9.1 and 13.9 months,*** surgical conversion rate was 34.0%(18/53),and 1-year overall survival was 83.0%without critical complicating diseases or adverse events(AEs).CONCLUSION The regimen of HAIC of FOLFOX,targeted therapy,and immunotherapy was curative for patients with unresectable HCC,with no serious AEs and a high rate of surgical conversion.

关键词： Hepatocellular carcinoma Hepatic arterial infusion chemotherapy Targeted therapy Immunotherapy Adverse events

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State transfer and entanglement between two-and four-level atoms in a cavity

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Chinese Physics B 2023年第10期32卷 522-530页

作者：李思吾冯田峰胡骁龙周晓祺 School of Physics Sun Yat-Sen UniversityGuangzhou 510275China

Qudits with a large Hilbert space to host quantum information are widely utilized in various applications, such as quantum simulation and quantum computation, but the manipulation and scalability of qudits still face challenges. Here, we propose a scheme to directly and locally transfer quantum information from multiple atomic qubits to a single qudit and vice versa in an optical cavity. With the qubit–qudit interaction induced by the cavity, our scheme can transfer quantum states efficiently and measurement-independently. In addition, this scheme can robustly generate a high-dimensional maximal entangled state with asymmetric particle numbers, showing its potential in realizing an entanglement channel. Such an information interface for qubits and qudit may have enlightening significance for future research on quantum systems in hybrid dimensions.

关键词： quantum state transfer quantum entanglement cavity quantum eletrodynamics

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Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao Peng Yuefeng Song Ihar Razanau Juanxiu xiao Wei xiao Di hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Activation energy

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Three-dimensional Potential Energy Surface and Bound States of the Ar2-Ne Complex

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Chinese Journal of Chemical Physics 2010年第5期23卷 549-552,621页

作者：牛梅许小涛陈侠胡小龙凤尔银安徽师范大学物理系芜湖241000

The first three-dimensional interaction potential energy surface （PES） of the Ar2-Ne complex is developed using the single and double excitation coupled cluster theory with noniterative treatment of triple excitations CCSD（T）. The aug-cc-pVQZ basis sets are employed for all atoms, including an additional （3s3p2d2flg） set of midpoint bond functions. The calculated single point energies are fitted to an analytic two-dimensional potential model at each of seven fixed rAr~ values. The seven model potentials are then used to construct the three- dimensional PES by interpolating along （r-re） using a sixth-order polynomial. The PES is used in the following rovibrational energy levels calculations. The comparisons of theoretical transition frequencies and spectroscopic constants with the experimental results are given.

关键词： Ar2-Ne complex Potential energy surface Rotational spectra

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Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

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Science China Chemistry 2025年第1期 273-287页

作者： Shuguang Yang Lijun hu Hong xiao Zecong xiao Xintao Shuai PCFM Lab of Ministry of Education School of Materials Science and Engineering Sun Yat-sen University Department of Ultrasound The Fifth Affiliated Hospital Sun Yat-sen University Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen University Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen University

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy. Nonetheless, the optimization of the catalytic efficiency is often impeded by the inefficient expression of enzymes. Herein, we reported a self-amplifying fluorescent molecular probe, Bis-HTPICG, for photodynamic therapy(PDT) and subsequent PDT-induced immunoreaction. The Bis-HTP-ICG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO), a crucial enzyme secreted by neutrophils at inflammation sites. Upon exposure to laser irradiation, Bis-HTP-ICG showed a high PDT efficacy, inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO secretion. The heightened level of MPO enhances the accumulation of the Bis-HTP-ICG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis, instigating a self-amplifying chain reaction cycle involving Bis-HTP-ICG, neutrophils and ***, PDT efficiently incites immunogenic cell death(ICD) in tumor cells, initiating an anti-tumor immune response including dendritic cells(DCs) maturation, T cell proliferation and reprogramming of tumor-associated neutrophils(TANs). This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

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具有3或4位全局校验的SD码和PMDS码的构造

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密码学报 2018年第2期5卷 151-166页

作者：荣幸杨小龙胡红钢中国科学技术大学中国科学院电磁空间信息重点实验室合肥230027

存储系统中的纠删码用在整个磁盘被擦除的错误模式下恢复丢失的数据.但在实际应用中,磁盘和扇区同时被擦除的情况更易发生.针对这种更一般的错误模式,Blaum等学者提出了SD码和PMDS码.相较应用于RAID存储架构中的纠删码,在磁盘和扇区同... 详细信息

存储系统中的纠删码用在整个磁盘被擦除的错误模式下恢复丢失的数据.但在实际应用中,磁盘和扇区同时被擦除的情况更易发生.针对这种更一般的错误模式,Blaum等学者提出了SD码和PMDS码.相较应用于RAID存储架构中的纠删码,在磁盘和扇区同时被擦除的错误模式下,SD码和PMDS码能够节省更多的存储空间.设计具有良好容错能力的SD码和PMDS码是一个公开问题.对SD码和PMDS码的构造主要基于校验矩阵或生成矩阵,但局部校验数m和全局校验数s均有限制.在已知的基于校验矩阵构造的SD码和PMDS码中,当全局校验个数s=3或4时,局部校验个数m满足m≤2;当局部校验个数m≥1时,全局校验个数s满足s≤2.在本文中,我们给出具有更高容错能力的SD码和PMDS码,参数满足m≥1且s=3.在已知的基于生成矩阵构造的SD码中,参数满足m≥1且s=3.在本文中,我们给出参数满足m≥1且s=4的SD码.

关键词：磁盘阵列 RAID SD码 PMDS码纠删码

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