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World Journal of Clinical Cases 2024年第9期12卷 1649-1659页

作者： Tie-Gong Wang Liang Tian xiao-ling zhang Lei zhang Xiu-Lei Zhao De-Shuai Kong Department of Surgery Cangzhou Central HospitalCangzhou 061000Hebei ProvinceChina Department of Pathology Cangzhou Central HospitalCangzhou 061000Hebei ProvinceChina

BACKGROUND Postoperative pancreatic fistula(POPF)contributes significantly to morbidity and mortality after pancreaticoduodenectomy(PD).However,the underlying mechanisms remain *** study explored this pathology in the pancreatic stumps and elucidated the mechanisms of POPF following *** SUMMARY Pathological analysis and 16S rRNA gene sequencing were performed on specimens obtained from two patients who underwent complete pancreatectomy for grade C POPF after *** inflammation is present in the pancreatic *** apoptosis was lower than that in the normal ***,neu-trophildominated inflammatory cells are concentrated in the ductal ***-tably,neutrophils migrated through the ductal wall in acinar duct metaplasia-formed ***,evidence indicates that gut microbes migrate from the digestive *** inflammation occurs in pancreatic stumps after *** The mechanisms underlying POPF include high biochemical activity in the pancreas,mechanical injury,and digestive *** prevent POPF and address pancreatic inflammation and reflux,breaking the link with anastomotic dehi-scence is practical.

关键词： Pancreaticoduodenectomy Postoperative pancreatic fistula Inflammation Digestive reflux Case report

Therapeutic Effectiveness of Leukocyte-and Platelet-rich Fibrin for Diabetic Foot Ulcers:A Retrospective Study

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Current Medical Science 2024年第3期44卷 568-577页

作者： Fen WANG xiao-ling zhang Jing zhang Song GONG Jing TAO Hui XIANG xiao-qing FU Xu-na BIAN Xue-feng YU An-hui XU Cheng-la YI Shi-ying SHAO Department of Endocrinology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Branch of National Clinical Research Center for Metabolic Diseases Wuhan430030China Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Trauma Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Diabetic foot ulcer(DFU)is one of the most serious complications of ***-and platelet-rich fibrin(L-PRF)is a second-generation autologous platelet-rich *** study aims to investigate the clinical effects of L-PRF in patients with diabetes in real clinical *** Patients with DFU who received L-PRF treatment and standard of care(SOC)from 2018 to 2019 in Tongji Hospital were *** clinical information including patient characteristics,wound evaluation(area,severity,infection,blood supply),SOC of DFU,and images of ulcers was retrospectively extracted and analyzed.L-PRF treatment was performed every 7±2 days until the ulcer exhibited complete epithelialization or an overall percent volume reduction(PVR)greater than 80%.Therapeutic effectiveness,including overall PVR and the overall and weekly healing rates,was *** Totally,26 patients with DFU were enrolled,and they had an ulcer duration of 47.0(35.0,72.3)*** severity and infection of ulcers varied,as indicated by the Site,Ischemia,Neuropathy,Bacterial Infection,and Depth(SINBAD)scores of 2–6,Wagner grades of 1–4,and the Perfusion,Extent,Depth,Infection and Sensation(PEDIS)scores of 2–*** initial ulcer volume before L-PRF treatment was 4.94(1.50,13.83)cm3,and the final ulcer volume was 0.35(0.03,1.76)*** median number of L-PRF doses was 3(2,5).A total of 11 patients achieved complete epithelialization after the fifth week of treatment,and 19 patients achieved at least an 80%volume reduction after the seventh *** overall wound-healing rate was 1.47(0.63,3.29)cm3/week,and the healing rate was faster in the first 2 weeks than in the remaining *** treatment did not change the percentage of complete epithelialization or healing *** Adding L-PRF to SOC significantly improved wound healing in patients with DFU independent of the ankle brachial index,SINBAD score,or Wagner grade,indicating that this method is appropriate for D

关键词： diabetic foot ulcer autologous platelet-rich plasma leukocyte-and platelet-rich fibrin standard of care percentage volume reduction

Conformal Vector Fields on Finsler Warped Product Manifolds

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Acta Mathematica Sinica,English Series 2023年第8期39卷 1624-1634页

作者： xiao ling zhang Ya Lu FENG College of Mathematics and Systems Science Xinjiang UniversityUrumqi 830046P.R.China

In this paper,we study the conformal vector fields on Finsler warped product *** obtain a system of equivalent equations that the conformal vector fields on Finsler warped product manifolds satisfy and completely char... 详细信息

关键词： Finsler warped product manifold conformal vector field homothetic vector field Killing vector field

S-curvature of Doubly Warped Product of Finsler Manifolds

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Acta Mathematica Sinica,English Series 2020年第11期36卷 1292-1298页

作者： Zhao YANG Yong HE xiao ling zhang College of Mathematics and Systems Science Xinmjiang UniversityUrumqi 830046P.R.China Department of Mathematics Xinjiang Normal UnitersityUrumqi 830017P.R.China College of Mathematics and Systems Science Xinjiang UniversityUrumqi 830046P.R.China

Doubly warped product of Finsler manifolds is useful in theoretical physics,particularly in general *** this paper,we study doubly warped product of Finsler manifolds with isotropic mean Berwald curvature or weak isot... 详细信息

关键词： Doubly warped product of Finsler manifold weak isotropic S-curvature isotropic mean Berwald curvature weakly Berwald manifolds

Investigation of shale gas microflow with the Lattice Boltzmann method

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Petroleum Science 2015年第1期12卷 96-103页

作者： xiao-ling zhang Li-Zhi xiao Long Guo Qing-Ming Xie State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum Key Laboratory of Shale Gas Exploration Ministry of Land and Resources Chongqing Institute of Geology and Mineral Resources

In contrast to conventional gas-bearing rocks, gas shale has extremely low permeability due to its nano- scale pore networks. Organic matter which is dispersed in the shale matrix makes gas flow characteristics more complex. The traditional Darcy＇s law is unable to estimate matrix permeability due to the particular flow mechanisms of shale gas. Transport mechanisms and influence factors are studied to describe gas transport in extremely tight shale. Then Lattice Boltzmann simulation is used to establish a way to estimate the matrix permeability numerically. The results show that net desorption, diffu- sion, and slip flow are very sensitive to the pore scale. Pore pressure also plays an important role in mass fluxes of gas. Temperature variations only cause small changes in mass fluxes. The Lattice Boltzmann method can be used to study the flow field in the micropore spaces and then provides numerical solutions even in complex pore structure models. Understanding the transport characteristics and establishing a way to estimate potential gas flow is very important to guide shale gas t＇eserve estimation and recovery schemes.

关键词： Shale gas Permeability Adsorption Desorption Diffusion Slip effect

Low temperature fabrication of flexible carbon counter electrode on ITO-PEN for dye-sensitized solar cells

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Chinese Chemical Letters 2010年第9期21卷 1137-1140页

作者： Li Li Chen Jia Liu Jing Bo zhang xiao Wen Zhou xiao ling zhang Yuan Lin Department of Chemistry School of Science Beijing Institute of Technology Beijing 100081 China Beijing National Laboratory for Molecular Sciences Key Laboratory. of Photochemistry Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China

A novel low temperature method was used to prepare the mesoporous carbon（MC） counter electrode（CE） on indium-doped tin oxide coated polyethylene naphthalate（ITO-PEN） for flexible dye-sensitized solar cells（DSSCs）.The obtained flexible MC CEs with carbon loading of 280μg cm^（-2） were characterized by SEM,XRD and electrochemical *** light-to-electricity conversion efficiency of the DSSC fabricated with the prepared flexible MC CE was 86%of that of DSSC based on the decomposited Pt CE.

关键词： Mesoporous carbon Flexible counter electrode Dye-sensitized solar cells

China's ETS pilots: Program design, industry risk, and long-term investment

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Advances in Climate Change Research 2022年第1期13卷 82-96页

作者： Kai LI Shao-Zhou QI Ya-Xue YAN xiao-ling zhang Climate Change and Energy Economics Study Center Wuhan UniversityWuhan 430070China Institute of Sociology Zhongnan University of Economics and LawWuhan 430073China Department of Public Policy City University of Hong KongHong Kong 999077China Shenzhen Research Institute City University of HongKongShenzhen 518057China

The emissions trading scheme(ETS)is considered an effective policy tool for achieving emission *** present,China's ETS pilots have completed several compliance periods and provided rich experience for a national *** advantage of the variations in the regional ETS pilots across regions and sectors and over time,this study used a difference-in-difference-in-differences(DDD)model to examine the effects of ETS pilots and differential program design on industry risk and the impacts of risk on future investment ***,we found that the ETS pilots significa ntly increase profit variability(total risk)in China's industry;that is,ETS in duces greater uncertainty in the covered *** terms of industry heterogeneity,non-eleclricily sectors(specifically ferrous metal)engage in higher levels of risk ***,the influence of such program features as the allowance allocation(total amounts and approaches),China Certification Emission Reduction(CCER)trading volumes,and penalties are ***,during the period around the treatment,industry risk can significantly encourage longer rather than shorter *** particular,the punishment mechanism and benchmarking allocation play a positive role in regulating the risk-investment relationship.

关键词： ETS Program design:Industry risk Long-term investment China

Epidemic Spread in Networks Induced by Deactivation Mechanism

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Communications in Theoretical Physics 2008年第5期49卷 1357-1360页

作者： YU xiao-ling WU xiao zhang Duan-Ming LI Zhi-Hao LIANG Fang WANG xiao-Yu Department of Physics Huazhong University of Science and Technology Wuhan 430074 China

We have studied the topology and epidemic spreading behaviors on the networks in which deactivation mechanism and long-rang connection are coexisted. By means of numerical simulation, we find that the clustering coefficient C and the Pearson correlation coefficient r decrease with increasing long-range connection μ and the topological state of the network changes into that of BA model at the end （when μ = 1）. For the Susceptible-Infect-Susceptible model of epidemics, the epidemic threshold can reach maximum value at μ = 0.4 and presents two different variable states around μ= 0.4.

关键词： epidemic threshold deactivation mechanism long-rang connection

Fc effector of anti-Aβ antibody induces synapse loss and cognitive deficits in Alzheimer’s disease-like mouse model

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Signal Transduction and Targeted Therapy 2023年第2期8卷 813-826页

作者： xiao-ying Sun xiao-lin Yu Jie Zhu ling-jie Li Lun zhang Ya-ru Huang Dong-qun Liu Mei Ji Xun Sun ling-xiao zhang Wei-wei Zhou Dongming zhang Jianwei Jiao Rui-tian Liu State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemistry and Chemical Engineering University of Chinese Academy of ScienceBeijing 100049China Innovation Academy for Green Manufacture Institute Chinese Academy of SciencesBeijing 100190China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China

Passive immunotherapy is one of the most promising interventions for Alzheimer’s disease(AD).However,almost all immune-modulating strategies fail in clinical trials with unclear causes although they attenuate neuropathology and cognitive deficits in AD animal ***,we showed that Aβ-targeting antibodies including their lgG1 and lgG4 subtypes induced microglial engulfment of neuronal synapses by activating CR3 or FcγRIIb via the complex of Aβ,antibody,and ***,anti-Aβantibodies without Fc fragment,or with blockage of CR3 or FcγRIIb,did not exert these adverse ***,Aβ-targeting antibodies,but not their Fab fragments,significantly induced acute microglial synapse removal and rapidly exacerbated cognitive deficits and neuroinflammation in APP/PS1 mice post-treatment,whereas the memory impairments in mice were gradually rescued *** the recovery rate of synapses in humans is much lower than that in mice,our findings may clarify the variances in the preclinical and clinical studies assessing AD ***,Aβ-targeting antibodies lack of Fc fragment,or with reduced Fc effector function,may not induce microglial synaptic pruning,providing a safer and more efficient therapeutic alternative for passive immunotherapy for AD.

关键词： Aβ Alzheimer inflammation

Intravitreal triamcinolone versus intravitreal bevacizumab for diabetic macular edema:a meta-analysis

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International Journal of Ophthalmology(English edition) 2013年第4期6卷 546-552页

作者： xiao-ling zhang Jian Chen Ri-Jia zhang Wen-Jie Wang Qing Zhou xiao-Yan Qin Department of Ophthalmology the First Affiliated Hospital of Jinan University

AIMTo compare the efficacy of the sole intravitreal triamcinolone (IVT) versus intravitreal bevacizumab (IVB) alone or IVB combined with IVT in the treatment of diabetic macular edema (DME).

关键词： triamcinolone bevacizumab diabetic macular edema meta-analysis