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TKN3 affects cell expansion to regulate fruit development in tomato

Horticultural Plant Journal 2025年第1期11卷 251-263页

作者： Shuai Sun Yaqin Yuan Meng Xu Zhiqiang Liu xiaowei Yuan Xingsheng Li Ren Li Xia cui Key Laboratory of Biology and Genetic Improvement of Horticultural Crops of the Ministry of Agriculture Sino-Dutch Joint Laboratory of Horticultural GenomicsInstitute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory of Qualityand Safety Control for Subtropical Fruitand Vegetable Ministry of Agriculture and Rural AffairsCollege of Horticulture ScienceZhejiang A&F UniversityHangzhouZhejiang 311300China Huasheng Agriculture Limited Liability Company QingzhouShangdong 262500China

Tomato is a model system for studying fleshy fruit *** fertilization,cell division and expansion in the pericarp are crucial for fruit development and determine the final fruit ***3 was found to be expressed in the tomato ovary wall/pericarp of zero to two days post-anthesis fruits as a KNOX I class member,but its function in fruit development was ***,we found that mutations of TKN3 by CRISPR/Cas9 caused fruit developmental defects,and fruit weight was dramatically reduced in the tkn3cr *** observation of fruit pericarps revealed that mutation of TKN3 repressed cell expansion after fertilization,leading to flattened cells in the mesocarp and thereby thinner pericarps in red ***,tkn3cr mutants also displayed pleiotropic phenotypes including enlarged leaves and floral organs,indicating conserved functions in meristem maintenance and leaf *** two-hybrid and BiFC assays further showed that TKN3 could interact with Solyc10g086640(a homolog of Arabidopsis PNY),which has a similar expression pattern as ***-wide identification of genes regulated by TKN3 indicated that the auxin and gibberellin(GA)pathways might mediate the function of *** works revealed that TKN3 controls cell expansion in pericarps,and provides new insights into the roles of KNOX proteins in fruit development.

关键词： Solanum lycopersicum TKN3 Tomato fruits Cell expansion BELLs Transcription factor

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Genetic diversity and population genetic structure of Paeonia suffruticosa by chloroplast DNA simple sequence repeats(cpSSRs)

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Horticultural Plant Journal 2025年第1期11卷 367-376页

作者： Qi Guo Xian Xue Duoduo Wang Lixia Zhang Wei Liu Erqiang Wang xiaoqiang cui xiaogai Hou College of Agriculture/College of Tree Peony Henan University of Science and TechnologyLuoyangHenan 471023China Luoyang Academy of Agricultural and Forestry Science LuoyangHenan 471027China Luanchuan County Agriculture and Rural Affairs Bureau Agricultural Technology Extension Service CenterLuoyangHenan 471599China

Paeonia suffruticosa *** an endemic shrub flower in China with 2n=*** study used 228 cultivars from four populations,i.e.,Jiangnan,Japan,Northwest,and Zhongyuan,as materials to explore the genetic diversity levels among different populations of tree peony *** results showed that 34 bands were amplified using five pairs of cp SSR primers,with an average of 6.8 bands per primer *** average number of different alleles(N_(a)),effective alleles(N_(e)),Shannon's information index(I),diversity(H),and polymorphic information content(PIC)were 3.600,2.053,0.708,0.433,and 0.388,*** PIC value was between 0.250 and 0.500,indicating a moderate level of polymorphism for the five cp SSR primer *** genetic diversity levels of peony cultivars varied among different populations,with the Northwest population showing relatively lower levels(I=0.590,H=0.289,and PIC=0.263).A total of 52 haplotypes were identified in the four examined populations,and the number of haplotypes per population ranged from 11 to ***-four private haplotypes were detected across populations,and the Northwest population exhibiting the highest count of private haplotypes with *** mean number of effective number of haplotypes(N_(eh)),haplotypic richness(R_(h)),and diversity(H)were 8.351,6.824,and 0.893,*** of molecular variance indicated that genetic variation within tree peony germplasm was greater than that between germplasm resources,and the main variation was found within individuals of peony *** analysis,principal coordinate analysis,and genetic structure analysis classified tree peonies from different origins into two groups,indicating a certain degree of genetic differentiation among these four tree peony cultivation *** study provides a theoretical basis for the exploration,utilization,and conservation of peony germplasm resources,as well as for research on the breeding of excellent varieties.

关键词： Paeonia suffruticosa Chloroplast microsatellites(cp SSR) Genetic diversity Haplotypes Germplasm resources

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抗阻训练改善乳腺癌术后患者淋巴水肿的效果评价

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中华护理杂志 2025年第2期60卷 185-193页

作者：王玲尚少梅施月仙王翠北京大学护理学院北京市100191

目的构建乳腺癌相关淋巴水肿抗阻训练方案并验证其可行性和有效性,旨在为乳腺癌术后患者康复锻炼提供借鉴。方法根据淋巴回流动力源中的肌肉收缩和胸腔负压2个可干预因素,结合乳腺癌相关淋巴水肿患者抗阻训练的最佳证据,制订乳腺癌相关... 详细信息

目的构建乳腺癌相关淋巴水肿抗阻训练方案并验证其可行性和有效性,旨在为乳腺癌术后患者康复锻炼提供借鉴。方法根据淋巴回流动力源中的肌肉收缩和胸腔负压2个可干预因素,结合乳腺癌相关淋巴水肿患者抗阻训练的最佳证据,制订乳腺癌相关淋巴水肿患者抗阻训练方案初稿。通过2轮专家论证和预试验对方案进行修订和可行性分析。采用便利抽样法,选取2022年1月—5月在合肥市某三级甲等医院的34例乳腺癌相关淋巴水肿患者作为试验组,2022年9月—2023年1月在芜湖市某三级甲等医院的34例乳腺癌相关淋巴水肿患者作为对照组。试验组和对照组都进行为期12周的综合消肿疗法(手法淋巴引流、穿戴压力衣和皮肤护理),试验组在此基础上进行为期12周的抗阻训练。收集干预前和干预后第2、4、8、12周两组患侧上肢的握力、患侧上肢细胞外液量与细胞内液量比值、第1秒用力呼气容积。结果乳腺癌相关淋巴水肿患者抗阻训练方案包括抗阻呼吸训练、抗阻肌肉训练、热身训练、放松训练4个部分。专家的权威系数为0.89,第1轮专家论证的肯德尔和谐系数为0.42,变异系数为0.08~0.27。第2轮专家论证的肯德尔和谐系数为0.67,变异系数为0~0.19。预试验结果显示,5例患者训练完成度为62.50%~100%,训练过程中无不良事件发生。试验组31例、对照组30例完成了12周的干预。重复测量方差分析显示,试验组的患侧上肢握力、第1秒用力呼气容积的增加幅度大于对照组(P<0.05),试验组的患侧上肢细胞外液量与细胞内液量比值的下降幅度大于对照组(P<0.05)。结论该研究构建的乳腺癌相关淋巴水肿患者抗阻训练方案具有一定的科学性、可行性,可以提高淋巴回流动力源中的肌肉收缩和胸腔负压,缓解淋巴水肿。

关键词：乳腺癌淋巴水肿抗阻训练淋巴回流动力源护理

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Impact of warming and nitrogen addition on soil greenhouse gas fluxes:A global perspective

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Journal of Environmental Sciences 2025年第5期151卷 88-99页

作者： Hongze Ma xiaoyu Jia Weiguang Chen Jingyi Yang Jin Liu xiaoshan Zhang Ke cui Zhouping Shangguan Weiming Yan State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau College of Soil and Water Conservation Science and EngineeringNorthwest A&F UniversityYanglingShaanxi 712100China Institute of Soil and Water Conservation Chinese Academy of SciencesYanglingShaanxi 712100China University of Chinese Academy of Sciences Beijing 100049China Shaanxi Institute of Geo-Environment Monitoring Xi’an 710000China

Global warming and nitrogen(N)deposition have a profound impact on greenhouse gas(GHG)fluxes and consequently,they also affect climate ***,the global combined effects of warming and N addition on GHG fluxes remain to be fully *** address this knowledge gap,a globalmeta-analysis of 197 datasets was performed to assess the response of GHG fluxes to warming and N addition and their interactions under various climate and experimental *** results indicate that warming significantly increased CO_(2)emissions,while N addition and the combined warming and N addition treatments had no impact on CO_(2)***,both warming and N addition and their interactions exhibited positive effects on N_(2)O *** the combined warming and N addition treatments,warming was observed to exert a positive main effect on CO_(2)emissions,while N addition had a positive main effect on N_(2)O *** interactive effects of warming and N addition exhibited antagonistic effects on CO_(2),N_(2)O,and CH_(4)emissions,with CH_(4)uptake dominated by additive ***,we identified biome and climate factors as the two *** findings indicate that both warming and N addition substantially impact soil GHG fluxes and highlight the urgent need to investigate the influence of the combination of warming and N addition on terrestrial carbon and N cycling under ongoing global change.

关键词： Warming Nitrogen(N)addition Greenhouse gas(GHG)fluxes Interactive effects Biome

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Physical Modeling of Reconfigurable Intelligent Surface for Channel Modeling

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China Communications 2025年第2期22卷 128-142页

作者： MiaoWei Dou Jianwu cui Yijun Yang Zhenyu School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Mobile Network and Multimedia Technology Shenzhen 518005China ZTE Corporation Shenzhen 518005China

In this paper,a physical model of RIS of bistatic polarized radar cross section is derived starting from the Stratton-Chu equations under the assumptions of physical optics,PEC,far field and rectangular RIS *** the context of important physical characteristics of the backscattering polarization of RIS,the modeling of the RIS wireless channel requires a tradeoff between complexity and accuracy,as well as usability and *** channel modeling of RIS systems,RIS is modelled as multi-equivalent virtual base stations(BSs)induced by multi polarized electromagnetic waves from different incident *** comparison between test and simulation results demonstrates that the proposed algorithm effectively captures the key characteristics of the general RIS element polarization physical model and provides accurate results.

关键词： channel modeling map-based hybrid channel model polarized model Reconfigurable intelligent surface(RIS)

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Synergistic promotion strategy of “dual-site” and “dual-path” to enhance the C–C coupling between CO_(2) and HCHO driven by photoelectrocatalysis

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Journal of Energy Chemistry 2025年第1期100卷 39-49页

作者： Hongqiang Yang Jianfeng Zheng Guoyu Wang Yifei Gao Yatao Yang Jia Li xiaojin Han Yan cui Zhanggen Huang National Key Laboratory of High Efficiency and Low Carbon Utilization of Coal Institute of Coal ChemistryChinese Academy of ScienceTaiyuan 030001ShanxiChina University of Chinese Academy of Science Beijing 100049China Shenyang University of Chemical Technology Shenyang 110142LiaoningChina

Photoelectrocatalytic coupling CO_(2)and volatile organic compounds (VOCs) is a promising green strategy for the synergistic conversion of the two carbon-containing resources to *** catalytic efficiency is always at the mercy of chemical inertness of CO_(2)and the competitive hydrogen evolution of ***,a modified g-C_(3)N_(4)/ZnAl-LDH Z-scheme heterojunction catalyst with dual reaction site was rationally designed and precisely *** Faraday efficiency of ethanol reached 68.67%with a corresponding formation rate of 227.3μmol g^(-1)h^(-1).As revealed by in-situ characterizations and density functional theory calculations,CO_(2)and HCHO were absorbed at Zn site and N site,***,*CO generated from CO_(2)and HCHO was converted to*CH_(3)O and*CHO on the dual-active-site *** detailed reaction mechanism experiments indicated that C–C coupling only occurred between*CO and*CH_(3)O in electrocatalysis *** from the“*CO+*CH_(3)O”path,another“*CO+*CHO”coupling path was also detected in photoelectrocatalytic *** selectivity of ethanol was significantly enhanced due to the synthesis of dual-site catalyst and the dual-path coupling path between CO_(2)and HCHO simultaneously driven by light and electricity.

关键词： g-C_(3)N_(4)/ZnAl-LDH heterojunction Z-scheme C-C coupling Ethanol

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Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance

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Chinese Journal of Natural Medicines 2025年第1期23卷 54-63页

作者： Pingping Lin Hong Chen Zekun cui Boyang Yu Junping Kou Fang Li Jiangsu Key Laboratory of TCM Evaluation and Translational Research Research Center for Traceability and Standardization of TCMs School of Traditional Chinese PharmacyChina Pharmaceutical University

Astragali Radix(AR) and Notoginseng Radix et Rhizoma(NR) are frequently employed in cardiovascular disease treatment. However, the efficacy of the AR-NR medicine pair(AN) in improving cardiac remodeling and its underlying mechanism remains unclear. This study aimed to evaluate AN's cardioprotective effect and potential mechanism on cardiac remodeling using transverse aortic constriction(TAC) in mice and angiotensin II(Ang II)-induced neonatal rat cardiomyocytes(NRCMs) and fibroblasts in vitro. High-performance liquid chromatography-quadrupole-time of flight tandem mass spectrometry(HPLC-Q-TOF-MS/MS) characterized 23 main components of AN. AN significantly improved cardiac function in the TAC-induced mice. Furthermore, AN considerably reduced the serum levels of N-terminal pro-B-type natriuretic peptide(NT-pro BNP), cardiac troponin T(CTn-T), and interleukin-6(IL-6) and mitigated inflammatory cell infiltration. Post-AN treatment, TAC-induced heart size approached normal. AN decreased cardiomyocyte cross-sectional area and attenuated the upregulation of cardiac hypertrophy marker genes(ANP, BNP, and MYH7) in vivo and in ***, AN alleviated collagen deposition in TAC-induced mice. AN also reduced the expression of fibrosis-related indicators(COL1A1 and COL3A1) and inhibited the activation of the transforming growth factor-β1(TGF-β1)/mothers against decapentaplegic homolog 3(Smad3) pathway. Thus, AN improved TAC-induced cardiac remodeling. Moreover, AN downregulated p-dynamin-related protein(Drp1)(Ser616) expression and upregulated mitogen 2(MFN-2) and optic atrophy 1(OPA1) expression in vivo and in vitro, thereby restoring mitochondrial fusion and fission balance. In conclusion, AN improves cardiac remodeling by regulating mitochondrial dynamic balance, providing experimental data for the rational application of Chinese medicine prescriptions with AN as the main component in clinical practice.

关键词： Astragali Radix−Notoginseng Radix et Rhizoma medicine pair Cardiac fibrosis Cardiac hypertrophy Mitochondrial dynamics Transforming growth factor-β1/Smad3 pathway

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Strategies for achieving fast-charge and high-voltage polymer-based solid-state lithium metal batteries

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Science China Chemistry 2025年

作者： Zitian Lin Sucheng Liu Ce cui Wuhua Liu Yufeng Su Huiyu Song Li Du Jianqiang Hu Zhiming cui Guangdong Provincial Key Laboratory of Fuel Cell Technology School of Chemistry and Chemical Engineering South China University of Technology

Solid-state polymer electrolytes hold the potential for market application due to the combination of advantageous properties,such as flexibility,ease of processing and low ***,the sluggish ion transport and poor high-voltage stability pose significant challenges for the practical application of polymer-based solid-state lithium metal batteries (SSLMBs).Therefore,the design and development of polymer-based SSLMBs toward fast-charge and high-voltage is of great significance in high-energydensity ***,this review deeply analyzes the mechanism of ion transport and anti-oxidation of polymer-based solidstate ***,we also systematically and comprehensively summarize the factors that affect ionic conductivity and the electrochemical ***,we outline the solution strategies for simultaneously enhancing both ionic conductivity and high-voltage ***,we discuss the main challenges and the future prospects of polymer-based SSLMBs for further *** is hoped that this review can provide both advances and fundamentals to the research community and pave the way for the development of SSLMBs

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NFT数字作品著作权侵权的风险检视与防治

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科技与法律(中英文) 2025年第2期 93-102页

作者：崔晓武汉大学法学院武汉430072

基于区块链技术的NFT数字作品具有确权优势,成为著作权保护的新形态。区块链的信任机制能够保证作品上链后版权信息的不可篡改,但当原作品存在著作权瑕疵时,NFT数字作品仍然面临侵犯复制权和信息网络传播权风险。数字时代的网络著作权... 详细信息

基于区块链技术的NFT数字作品具有确权优势,成为著作权保护的新形态。区块链的信任机制能够保证作品上链后版权信息的不可篡改,但当原作品存在著作权瑕疵时,NFT数字作品仍然面临侵犯复制权和信息网络传播权风险。数字时代的网络著作权侵权治理亟须实现从行政监管向平台共治的范式转型,这一转向得到了现有规范性文件、行政监管策略以及司法判例的支持。当下NFT数字作品平台在防治著作权侵权中的职能角色与责任承担范围并不合理,“避风港原则”与“红旗原则”不应被视为其免责的正当性理据。基于平台的控制能力和营利模式等因素,NFT数字作品平台应当构建与完善著作权审核机制,并在获知侵权线索后及时采取必要措施遏止侵权结果的扩散。

关键词：区块链 NFT数字作品著作权保护平台共治注意义务

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Metal-free construction of diverse 1,2,4-triazolo[1,5-a]pyridines on water

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Chinese Chemical Letters 2025年第1期36卷 244-247页

作者： Chunhua Ma Mengjiao Liu Siyu Ouyang Zhenwei cui Jingjing Bi Yuqin Jiang Zhiguo Zhang Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and ReactionsMinistry of EducationHenan Engineering Research Centre of Chiral Hydroxyl PharmaceuticalHenan Engineering Laboratory of Chemical Pharmaceutical and Biomedical MaterialsSchool of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiang 453007China Chongqing Aoshe Bio-chemical Co.Ltd. Chongqing 400000China

A transition-metal-and oxidant-free amination/cyclization reaction to access 1,2,4-triazolo[1,5-a]pyridines was realized in water by using amino diphenylphosphinate as amino source.A broad array of readily accessible N-(pyridyl)amides could be converted into the products featuring a diverse set of functional *** sustainable methodology was successfully applied to the late-stage functionalization of natural products and drugs.

关键词： 1,2,4-Triazolo[1,5-a]pyridines On water N-(Pyridyl)amides Cyclization Metal-free

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