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Pre-stack basis pursuit seismic inversion for brittleness of shale

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Petroleum Science 2015年第4期12卷 618-627页

作者： Xing-Yao Yin xiao-jing liu Zhao-Yun Zong School of Geosciences China University of Petroleum (Huadong)

Brittleness of rock plays a significant role in exploration and development of shale gas reservoirs. Young＇s modulus and Poisson＇s ratio are the key param- eters for evaluating the rock brittleness in shale gas exploration because their combination relationship can quantitatively characterize the rock brittleness. The high- value anomaly of Young＇s modulus and the low-value anomaly of Poisson＇s ratio represent high brittleness of shale. The technique of pre-stack amplitude variation with angle inversion allows geoscientists to estimate Young＇s modulus and Poisson＇s ratio from seismic data. A model constrained basis pursuit inversion method is proposed for stably estimating Young＇s modulus and Poisson＇s ratio. Test results of synthetic gather data show that Young＇s modulus and Poisson＇s ratio can be estimated reasonably. With the novel method, the inverted Young＇s modulus and Poisson＇s ratio of real field data focus the layer boundaries better, which is helpful for us to evaluate the brittleness of shale gas reservoirs. The results of brittleness evaluation show a good agreement with the results of well interpretation.

关键词： Brittleness Shale gas Amplitude variationwith angle Basis pursuit Bayesian framework

Probiotic Mixture VSL#3 Alleviates Dextran Sulfate Sodium-induced Colitis in Mice by Downregulating T Follicular Helper Cells

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Current Medical Science 2019年第3期39卷 371-378页

作者： xiao-jing liu Ran YU Kai-fang ZOU Division of Gastroenterology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022 China Department of Stomatology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Clinical trials have shown beneficial effects of probiotics on inflammatory bowel diseases (IBD), although the exact mechanism remains unknown. VSL#3, a mixture of 8 probiotic bacteria, has been confirmed to have adjunctive therapeutic effects on colitis. T follicular helper (Tfh) cells, a new separate subset of CD4+ T helper cells, have been proved to play a vital role in autoimmunity. The present study aimed to identify the beneficial effect of the probiotic mixture VSL#3 on the mouse model of colitis by regulating Tfh cells. Dextran sulfate sodium (DSS) was used to induce chronic colitis in C57BL/6 mice. VSL#3 (3x109 live bacteria) was given to C57BL/6 mice every other day for 60 days by gavage. The disease activity index (DAI), histological activity index (HAI), colon length and myeloperoxidase (MPO) activity were detected. Immunofluorescence was used to visualize the location of Tfh cells. Immunoglobulins, Tfh cells and plasma cells were quantified by enzyme-linked immunosorbent assay (ELISA), flow cytometry, real-time PCR or Western blotting. The results showed that after DSS treatment, the humoral immunity was disordered in C57BL/6 mice, with increased IgM, IgG and IgA levels in colonic mucus and increased Tfh cells in mesenteric lymph nodes (MLN). VSL#3 treatment showed anti-inflammatory effects as evidenced by reduced DAI score, HAI score and MPO activity. IgM, IgG and IgA levels were significantly reduced in colon mucus, and the number of Tfh cells was markedly decreased in MLN after VSL#3 treatment. It was concluded that VSL#3 alleviates DSS-induced colitis by downregulating Tfh cells, and Tfh cells may become a potential therapeutic target for IBD.

关键词： T follicular helper cells probiotics VSL#3 humoral immunity inflammatory bowel disease

SP3-coupled global variance reduction method based on RMC code

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Nuclear Science and Techniques 2021年第11期32卷 42-51页

作者： Qing-Quan Pan Teng-Fei Zhang xiao-jing liu Hui He Kan Wang School of Nuclear Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Engineering Physics Tsinghua UniversityBeijing 100084Chin

A global variance reduction(GVR)method based on the SPN method is ***,the global multi-group cross-sections are obtained by Monte Carlo(MC)global ***,the SP3 equation is solved to obtain the global flux ***,the global weight windows are approximated by the global flux distribution,and the GVR simulation is *** GVR method is implemented as an automatic process in the RMC *** SP3-coupled GVR method was tested on a modified version of C5 G7 benchmark with a thickened water *** results show that the SP3-coupled GVR method can improve the efficiency of MC criticality calculation.

关键词： RMC code Global homogenization Variance reduction SPN theory

Semi-empirical and semi-quantitative lightweight shielding design method

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Nuclear Science and Techniques 2023年第3期34卷 109-124页

作者： Song-Chuan Zheng Qing-Quan Pan Huan-Wen Lv Song-Qian Tang xiao-jing liu College of Smart Energy Shanghai Jiao Tong UniversityShanghai 200240China School of Nuclear Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of ChinaChengdu 610200China

The lightweight shielding design of small reactors is a popular research *** on a small helium-xenon-cooled solid reactor,the effects of neutron and photon shielding sequence and the number of shielding layers on the radiation dose were first *** was found that when photons were shielded first and the number of shielding layers was odd,the radiation dose could be significantly *** reduce the weight of the shielding body,the relative thickness of the shielding layers was optimized using the genetic *** optimized scheme can reduce the radiation dose by up to 57%and reduce the weight by 11.84%.To determine the total thickness of the shielding layers and avoid the local optimal solution of the genetic algorithm,a series of formulas that describes the relationship between the total thickness and the radiation dose was developed through large-scale calculations.A semi-empirical and semi-quantitative lightweight shielding design method is proposed to integrate the above shielding optimization method that verified by the Monte Carlo ***,a code,SDIC1.0,was developed to achieve the optimized lightweight shielding design for small *** was verified that the difference between the SDIC1.0 and the RMC code is approximately 10%and that the computation time is shortened by 6.3 times.

关键词： Small reactor Lightweight Shielding calculation Genetic algorithm

Syntheses,structures,luminescent and magnetic properties of two coordination polymers based on a flexible multidentate carboxylate ligand

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Chinese Chemical Letters 2015年第5期26卷 499-503页

作者： Dan Tian xiao-jing liu Rong-Ying Chen Ying-Hui Zhang Department of Chemistry and TKL of Metal-and Molecule-Based Material Chemistry Key Laboratory of Advanced Energy Materials Chemistry(MOE)and Collaborative Innovation Center of Chemical Science and Engineering(Tianjin)Nankai University

Two coordination polymers, {[Cu3（tci）2（DMAc）3].6DMAc-2H2O}n （1[） and {[Cu3（tci）2（tpt）2（H2O）2]- 2DMAc-2H2O}n （2）（H3tci = tris（2-carboxyethyl）isocyanurate, tpt = 2,4,6-tris（4-pyridyl）-l,3,5-triazine, DMAc = N,N-dimethylacetamide）, have been constructed under solvothermal conditions. Both polymers were structurally characterized by single crystal X-ray diffraction, elemental analyses, IR spectra, thermogravimetric （TG） analyses and powder X-ray diffraction （RXPD）. 1 shows a （3,4）-connected 2D layer structure comprising Cu2（CO2）4 paddle-wheel units, which are further bridged by C-H.--O interactions to give a 3D supramolecular network. The introduction oftpt produces different framework for 2 that comprises a dinuclear and a mononuclear Cu（II） building units, which are further bridged together by tci3- and tpt ligands to give a 4-connected 2D topological net. Adjacent 2D layers are packed together via C-H...O interactions and π...π stacking interactions to form a 3D supramolecular structure. In addition, the luminescent properties and the solid-state UV-vis spectra of I and 2 were explored. Furthermore, antiferromagnetic exchange interactions were unveiled in the Cu2（COO）4 units of 1. ~ 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

关键词： Coordination polymers X-ray crystallography Copper Magnetic properties Luminescence

One inorganic–organic hybrid derived from reduced molybdophosphate and trinuclear cadmium(II) fragment

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Chinese Chemical Letters 2013年第10期24卷 877-880页

作者： Xiu-Li Wang jing-jing Cao Ji-Lin Hou Guo-Cheng liu Dan Zhao xiao-jing liu Na Li Ai-Xiang Tian Department of Chemistry Bohai UniversityLiaoning Province Silicon Materials Engineering Technology Research Center

One new polyoxometalate （POM）-based inorganic-organic hybrid [Cdn3~HPO4）（Hbpp）（H20）2]{CdII[P4_ Mo6028H3.s（OH）312}.（H4tpb）.7H20 （1）（bpp = 1,3-bis-（4-pyridyl）propane, tpb = 1,2,4,5-tetra（4-pyridyl）- benzene） constructed from reduced molybdophosphate [P4Mo6028H3.5（OH）3]s＇5- （P4Mo6）, trinuclear Cdn-phosphate-Hbpp fragment and protonated tpb has been hydrothermally synthesized and structurally characterized by IR, elemental analyses and single crystal X-ray diffraction. The complex 1 crystallizes in the monoclinic system with the space group P21]c and cell parameters of a=15.672（12）A, b=23.839（19）A, c=27.654（2）,~, fl=115.850（10）~, V=9297.9（12） ~3, Z=4, R1 ~0.0534 and wR2 ~0.1135. In complex 1, the P4Mo6 units are bridged by CdII ions to form the classic sandwich-type [Cd（P4Mo6）2] dimers, which are further connected into a two dimensional network via the trinuclear Cdn subunits. The tpb is synthesized in situ from the bpp ligands and connects the adjacent 2D layers into a 3D supramolecular framework through hydrogen bonding interactions. The electrochemical and fluorescent properties of complex 1 have been investigated.

关键词： Reduced molybdophosphate Cadmium(ll) complex In situ synthesis Multi-pyridine ligand

Numerical and theoretical investigations of heat transfer characteristics in helium-xenon cooled microreactor core

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Nuclear Science and Techniques 2023年第11期34卷 1-19页

作者： Tian‑Shi Wang Xiang Chai Chao‑Ran Guan Xin‑Yue liu Jiao‑Long Deng Hui He xiao‑jing liu School of Nuclear Science and Engineering Shanghai JiaoTong UniversityShanghai 200240China

Helium-xenon cooled microreactors are a vital technological solution for portable nuclear reactor power *** exam-ine the convective heat transfer behavior of helium-xenon gas mixtures in a core environment,numerical simulations are conducted on a cylindrical coolant channel and its surrounding solid *** numerical methods are used to determine the effect and mechanisms of power and its distribution,inlet temperature and velocity,and outlet pressure on the distribution and change trend of the axial Nusselt ***,a theoretical framework that can describe the effect of power variation on the evolution of the thermal boundary layer is employed to formulate an axial distribution cor-relation for the Nusselt number of the coolant channel,under the assumption of a cosine distribution for the axial *** on the simulation results,the correlation coefficients are determined,and a semi-empirical relationship is identified under the corresponding operating *** correlation derived in this study is consistent with the simulations,with an average relative error of 5.3%under the operating ***,to improve the accuracy of the predictions near the entrance,a segmented correlation is developed by combining the Kays correlation with the aforementioned *** new correlation reduces the average relative error to 2.9%and maintains satisfactory accuracy throughout the entire axial range of the channel,thereby demonstrating its applicability to turbulent heat transfer calculations for helium-xenon gas mixtures within the core *** findings provide valuable insights into the convective heat transfer behavior of a helium-xenon gas mixture in a core environment.

关键词： Helium-xenon gas mixture Convective heat transfer Power distribution Numerical simulation Nusselt number correlation

The receptor tyrosine kinase torso regulates ecdysone homeostasis to control developmental tinning in Bombyx mori

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Insect Science 2021年第6期28卷 1582-1590页

作者： Zhong-Jie Zhang xiao-jing liu Ye Yu Fang-Ying Yang Kai Li School of Life Science East China Normal UniversityShanghai 200062China Key Laboratory of Insect Developmental and Evolution-ary Biology Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China

Insect growth and development are precisely controlled by hormone *** prothoracicotropic hormone(PTTH)receptor,Torso,is a member of the receptor tyrosine kinase family in *** of Torso by PTTH triggers biosynthesis and release of the steroid hormone in the prothoracic gland(PG).Although numbers of genes functioning in steroid hormone synthesis and metabolism have been identified in insects,the PTTH transduction pathway via its receptor Torso is poorly *** the current study,we describe a loss-of-function analysis of Torso in the silkworm,Bombyx mori,by targeted gene disruption using the transgenic CRISPR/Cas9(clustered regularly interspaced short palindromic repeats/RNA-guided Cas9 nucleases)*** of *** Torso(BmTorso)did not eventually affect larval ecdysis and metamorphosis ***,BmTorso deficiency resulted in significant extension of developing time during larval and pupal stages with increased pupa and cocoon *** eedysteriod titers in the hemolymph of BmTorso mutants sharpy *** levels of genes involved in ecdysone biosynthesis and eedysteroid signaling pathways were significantly reduced in BniTorso-defic'iQnt ***,RNA-Seq analysis revealed that genes involved in the longevity pathway and protein processing in the endoplasmic reticulum pathway were affected after BmTorso *** results indicate that Torso is critical for maintaining steroid hormone homeostasis in insects.

关键词： Bombyx mori CRISPR/Cas9 developmental timing Torso

Dynamic evaluation of a scaled-down heat pipe-cooled system during start-up/shut-down processes using a hardware-in-the-loop test approach

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Nuclear Science and Techniques 2023年第11期34卷 174-198页

作者： Jiao‑Long Deng Tian‑Shi Wang En‑Ping Zhu Shuo Yuan xiao‑jing liu Xiang Chai School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Micro-mobile heat pipe-cooled nuclear power plants are promising candidates for distributed energy resource power genera-tors and can be flexibly deployed in remote places to meet increasing electric power ***,previous steady-state simulations and experiments have deviated significantly from actual micronuclear system ***,a transient analysis is required for performance optimization and safety *** this study,a hardware-in-the-loop(HIL)approach was used to investigate the dynamic behavior of scaled-down heat pipe-cooled *** real-time features of the HIL architecture were interpreted and validated,and an optimal time step of 500 ms was selected for the thermal *** power transient was modeled using point kinetic equations,and a scaled-down thermal prototype was set up to avoid mod-eling unpredictable heat transfer behaviors and feeding temperature samples into the main program running on a desktop PC.A series of dynamic test results showed significant power and temperature oscillations during the transient process,owing to the inconsistency of the rapid nuclear reaction rate and large thermal *** proposed HIL approach is stable and effective for further studying of the dynamic characteristics and control optimization of solid-state small nuclear-powered systems at an early prototyping stage.

关键词： Micro-heat pipe-cooled nuclear reactor Hardware-in-the-loop Dynamic evaluation Start-up/shut-down processes