检索结果-南通市图书馆

Modular construction mechanics of a European pressurized reactor steel containment liner

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第6期18卷 467-486页

作者： Jia-chuan YAN xiao-fei jin Feng QIN Zheng LI Feng FAN jin-ping OU Key Lab of Structures Dynamic Behavior and Control of the Ministry of Education Harbin Institute of Technology Harbin 150090 China School of Civil Engineering Harbin Institute of Technology Harbin 150090 China China Construction First Engineering Division Corporation Limited Beijing 101300 China Country Garden Foshan 528312 China China Construction Second Engineering Bureau Nuclear Power Plants Branch Shenzhen 518034 China

A European pressurized reactor （EPR） steel containment liner structure is comprised of the cylinder part and the dome part. An introduction of the steel liner structure is presented, followed by studies on the key mechanical features of the construction process using a refined finite element method. The steel liner was divided into several modules and then assembled during construction. Firstly, the equipment structure used to hoist the liner module was optimized, the lifting lug was analyzed using a multi-scale finite element model; the wind speed limit during lifting was also studied. Subsequently, the effect of internal forces during assembly between the liner modules, the lateral pressure of fresh concrete, the non-uniform temperature load, and the wind load on the cylinder module was analyzed. According to the time-varying structural performance during continuous concrete pouring and the hardening construction, an ＂overlapping element and birth-death element＂ technique was adopted to analyze the deformation and stress of the long-span steel dome liner. In addition, the stability-bearing capacities of the dome structure during construction were also studied, which took into consideration the effect of the initial geometrical imperfections and the elasto-plasticity of the material. This study presents a reference in terms of the mechanics of the construction scheme and the safety of such a type of structure.

关键词： Containment Construction mechanics Steel liner Overlapping element Birth-death element

Clinical Value of Hepatoma-Specific Alpha-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Clinical Oncology 2006年第3期3卷 153-157页

作者： Runzhou Ni Mingbing xiao fei jin Cuihua Lu Jiefei Huang Xianyong Meng Department of Gastroenterology Affiliated Hospital of Nantong University Nantong 226001 Jiangsu Province China.

OBJECTIVE To study the clinical value of hepatoma-specific alpha-feto- protein (HS-AFP) in the diagnosis and differential diagnosis of hepato- cellular carcinoma (HCC). METHODS A method of vertical slab polyacrylamide gel electrophoresis with discontinuous buffer system was developed to separate AFP sub- types. After separation, the AFP subtypes were transferred to nitrocellu- lose and reacted first with rabbit anti-human AFP and then with goat an- ti-rabbit IgG -HRP. Finally, AFP subtypes were visualized by reacting with 3,3’-diaminobenzidine tetrahydrochloride. A HS-AFP band was de- termined in 82 cases with HCC and 95 cases with benign liver diseases. The correlations between the positive rates of HS-AFP and serum AFP concentration, tumor size as well as portal vein metastasis were analyzed. RESULTS Serum AFP in the cases with various liver diseases was sepa- rated into one to several bands. The fastest band on electrophoresis (F- AFP) was found in all patients, while the band at the cathodal site (HS- AFP) was detected predominantly in HCC but rarely in benign liver dis- eases. The positive rate of HS-AFP in HCC was 74.4%, which was sig- nificantly higher than that in benign liver diseases (9.1%, 7.3% and 10.0% in liver cirrhosis, chronic hepatitis and acute hepatitis respectively). HS- AFP was detected in 3 out of 9 HCC cases with AFP<50 μg/L , but in none of 22 cases of benign liver diseases with the same AFP concentra- tion. HS-AFP correlated with serum AFP concentration and tumor size to some extent, but not with portal vein metastasis. CONCLUSION HS-AFP increases the sensitivity of diagnosing HCC in patients with negative AFP, and is useful in distinguishing high AFP due to HCC from that caused by benign liver diseases.

关键词： hepatoma alpha-fetoprotein heterogeneity diagnosis.

生物肽不同结构肽链对生物修饰金属材料疏水性能的影响

在线全文

学校读者我要写书评

暂无评论

表面技术 2019年第1期48卷 141-146页

作者：麻春英袁成清肖劲飞武汉理工大学武汉430063 华东交通大学南昌330013

目的通过调整与金属反应的肽的肽链结构,提高反应后金属表面的疏水性。方法取同种肽两种不同结构(L-型和D-型反序结构)分别与金属不锈钢作用,通过CA测定材料疏水性的变化,采用FTIR显示有机肽在材料表面的附着情况。分别在L-型和D-型肽... 详细信息

目的通过调整与金属反应的肽的肽链结构,提高反应后金属表面的疏水性。方法取同种肽两种不同结构(L-型和D-型反序结构)分别与金属不锈钢作用,通过CA测定材料疏水性的变化,采用FTIR显示有机肽在材料表面的附着情况。分别在L-型和D-型肽上接入疏水基团十二烷酸,获得两种新的不同结构的肽:L'-型肽和D'-型肽。两种肽分别与金属不锈钢作用,利用FTIR和CA研究疏水基团的接入及其对材料疏水性的影响情况。结果与金属不锈钢作用之后,D型肽反序结构修饰的不锈钢表面接触角比L型肽修饰有所提高,由原来的39.7°变成80.1°。接入疏水基团后的肽在PBS中的溶解度减小,用有机溶剂初溶之后再溶入PBS中,生物肽全部溶解。该肽溶液与金属材料作用之后,D'型肽比L'型肽作用的表面接触角更高,分别为89.4°和87.4°,前者作用效果更好。结论通过调整生物肽肽链的结构,可以改变改性金属材料表面的疏水特性,为进一步通过调整金属反应肽的肽链结构和疏水基团的种类得到具有良好疏水性能的金属材料提供了有力的数据支撑。

关键词：生物肽肽链结构手性异构表面改性疏水性接触角

基于K-L变换和模糊集理论的彩色字符图像分割

在线全文

学校读者我要写书评

暂无评论

计算机应用 2010年第9期30卷 2464-2466页

作者：肖劲飞王晓宇陈斌孙晓刚刘兵中国科学院成都计算机应用研究所成都610041

根据彩色印刷字符图像的特点,在Lab颜色空间下提取a分量,将彩色图像转换为灰度图像。根据模糊逻辑和阈值分割方法将图像分为目标区域、背景区域以及模糊区域。用K-L变换组合邻域的区域隶属信息和灰度信息,将灰度域换成模糊域,在该模糊... 详细信息

根据彩色印刷字符图像的特点,在Lab颜色空间下提取a分量,将彩色图像转换为灰度图像。根据模糊逻辑和阈值分割方法将图像分为目标区域、背景区域以及模糊区域。用K-L变换组合邻域的区域隶属信息和灰度信息,将灰度域换成模糊域,在该模糊域上进行分割。经实践,该算法在工业环境中对复杂背景的彩色印刷图像可以得到较好的分割效果,其时间复杂度不高于传统的阈值分割算法,并且在分割的精确度上要优于传统的阈值分割算法。

关键词：模糊逻辑彩色印刷图像分割阈值分割 K-L变换模糊域

在线全文

学校读者我要写书评

暂无评论

基于生物修饰的304不锈钢表面抗菌性能

中国表面工程 2017年第3期30卷 1-7页

作者：曹攀杨膺袁成清肖劲飞白秀琴武汉理工大学能源与动力工程学院武汉430063 英国基尔大学医药科技研究所

为了研究生物修饰对材料表面抗菌性能的影响,利用多巴胺及三种生物多肽修饰304不锈钢的表面,利用傅里叶变换红外光谱仪(FTIR)和接触角测量仪研究修饰后的材料表面性质,选用金黄色葡萄球菌(***)作为试验菌株研究样本表面抗菌性能,并通过... 详细信息

为了研究生物修饰对材料表面抗菌性能的影响,利用多巴胺及三种生物多肽修饰304不锈钢的表面,利用傅里叶变换红外光谱仪(FTIR)和接触角测量仪研究修饰后的材料表面性质,选用金黄色葡萄球菌(***)作为试验菌株研究样本表面抗菌性能,并通过超景深三维显微系统初步研究了样本表面形貌对抗菌性能的影响。结果表明,多巴胺和生物肽修饰后,样本表面的湿润性发生了改变,且都具有抗菌效果,1号多肽抗菌效果最好,多巴胺修饰样本的抗菌效果最差;不同颗粒度砂纸、不同抛磨压力处理的样本表面会影响材料表面性能,600号砂纸抛光的样本经生物修饰后抗菌效果优于2 000号砂纸抛光的样本,这个结论同样适用于开放环境中。

关键词：生物膜抗菌吸附量

在线全文

学校读者我要写书评

暂无评论

甲醛对作业工人免疫系统的损伤作用

环境与职业医学 2010年第10期27卷 640-640,644页

作者：童智敏施健杜成费小进江苏省昆山市疾病预防控制中心职业病防治科江苏昆山215301

[目的]探讨甲醛对作业工人免疫系统的影响。[方法]调查分析昆山市存在甲醛职业危害的企业,选择65名甲醛作业工人和非甲醛暴露工人70名为研究对象,采集工人静脉血,经仪器自动分析,测定作业工人血清补体C3、C4及血清免疫球蛋白IgA、IgG、... 详细信息

[目的]探讨甲醛对作业工人免疫系统的影响。[方法]调查分析昆山市存在甲醛职业危害的企业,选择65名甲醛作业工人和非甲醛暴露工人70名为研究对象,采集工人静脉血,经仪器自动分析,测定作业工人血清补体C3、C4及血清免疫球蛋白IgA、IgG、IgM。[结果]18家企业甲醛最高浓度达3.11mg/m3,超标作业点达29.09%。暴露组作业工人血清补体C3(0.99±0.31)、IgM(1.16±0.51);≥5年组作业工人血清补体C(30.85±0.15)、C4(0.20±0.05)及血清IgA(1.28±0.57)、IgM(0.90±0.35)明显降低,与对照组比较差异有统计学意义(P<0.01)。[结论]接触甲醛导致作业工人免疫功能抑制。

关键词：甲醛补体免疫球蛋白免疫抑制

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong jing-jing Hu Yan Yu xiao-Li Li xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu xiao-Jia Yang Qian-Ru He fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： xiaoqin Li Jian Xiang Lu Qiu xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan xiao Zhaoyu jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

低对比度下水印图像缺陷检测

计算机应用 2010年第11期30卷 2983-2985,3031页

作者：李全文阮波徐可佳于勇肖劲飞中国科学院成都计算机应用研究所成都610041

在主成分分析(PCA)及核主成分分析(KPCA)进行特征提取基本原理的基础上,提出了一种改进的提取非线性的图像特征来重建图像方法,应用于嵌入式防伪水印图案缺陷的检测。该方法使得图像协方差矩阵维数大幅下降,且有效地保留了嵌入式防伪水... 详细信息

在主成分分析(PCA)及核主成分分析(KPCA)进行特征提取基本原理的基础上,提出了一种改进的提取非线性的图像特征来重建图像方法,应用于嵌入式防伪水印图案缺陷的检测。该方法使得图像协方差矩阵维数大幅下降,且有效地保留了嵌入式防伪水印图案的信息,通过比较检测出图像的缺陷。实验结果表明,该方法对输入数据实现了有效的降维,缩短了计算时间,提高了检测效果和精确度。KPCA算法相比原有的PCA算法具有更高的性能指标,适用范围更广。

关键词：核主成分分析水印图案缺陷检测