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Journal of China University of Mining and Technology 2008年第3期18卷 368-372页

作者： LI xiao-bo wang Chong-lin School of Information ＆ Electrical Engineering China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China

When, in a coal mine distribution network whose neutral point is grounded by an arc suppression coil (ASC), a fault occurs in the ASC, compensation cannot be properly realized. Furthermore, it can damage the safe and reliable run of the network. We first introduce a three-phase five-column arc suppression coil (TPFCASC) and discuss its autotracking compensation theory. Then we compare the single phase to ground fault of the coal mine distribution network with an open phase fault at the TPFCASC using the Thévenin theory, the symmetrical-component method and the complex sequence network respectively. The results show that, in both types of faults, zero-sequence voltage of the network will appear and the maximum magnitude of this zero-sequence voltage is different in both faults. Based on this situation, a protection for the open phase fault at the TPFCASC should be estab-lished.

关键词： open phase protection single phase to ground fault three-phase five-column arc suppression coil (TPFCASC)

Painlevé property, local and nonlocal symmetries, and symmetry reductions for a (2+1)-dimensional integrable KdV equation

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Chinese Physics B 2021年第1期30卷 178-184页

作者： xiao-bo wang Man Jia Sen-Yue Lou School of Physical Science and Technology Ningbo UniversityNingbo 315211China

The Painlevé property for a(2+1)-dimensional Korteweg–de Vries(KdV) extension, the combined KP3(Kadomtsev–Petviashvili) and KP4(cKP3-4), is proved by using Kruskal’s simplification. The truncated Painlevé expansion is used to find the Schwartz form, the Bäcklund/Levi transformations, and the residual nonlocal symmetry. The residual symmetry is localized to find its finite Bäcklund transformation. The local point symmetries of the model constitute a centerless Kac–Moody–Virasoro algebra. The local point symmetries are used to find the related group-invariant reductions including a new Lax integrable model with a fourth-order spectral problem. The finite transformation theorem or the Lie point symmetry group is obtained by using a direct method.

关键词： Painlevéproperty residual symmetry Schwartz form Bäcklund transforms D’Alembert waves symmetry reductions Kac–Moody–Virasoro algebra (2+1)-dimensional KdV equation

Immunotherapy with dendritic cells and cytokine-induced killer cells for hepatocellular carcinoma: A meta-analysis

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World Journal of Gastroenterology 2019年第27期25卷 3649-3663页

作者： Jing Cao Fan-Hua Kong Xi Liu xiao-bo wang Department of Surgery Technical University of MunichMunich 80333Germany Department of General Surgery The Second Xiangya HospitalCentral South UniversityChangsha 410011Hunan ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC) has been revealed as the second most common cause of cancer-related deaths worldwide. The introduction of cell-based immunotherapy, including dendritic cells(DCs) and cytokine-induced killer cells(CIKs), has brought HCC patients an effective benefit. However, the efficacy and necessity of cellular immunotherapy after different interventional therapy remains to be further *** To investigate the efficacy of cellular immunotherapy, involving DCs and CIKs,combined with different conventional treatments of *** We performed a literature search on PubMed and Web of Science up to February15, 2019. Long-term efficacy(overall survival and recurrence) and short-term adverse effects were investigated to assess the effectiveness of immunotherapy with DCs and/or CIKs. Review Manager 5.3 was used to perform the *** A total of 22 studies involving 3756 patients selected by eligibility inclusion criteria were forwarded for meta-analysis. Combined with the conventional clinical treatment, immunotherapy with DCs and/or CIKs was demonstrated to significantly improve overall survival at 6 mo [risk ratio(RR) = 1.07;95%confidence interval(CI): 1.01-1.13, P = 0.02], 1 year(RR = 1.12;95%CI: 1.07-1.17, P< 0.00001), 3 years(RR = 1.23;95%CI: 1.15-1.31, P < 0.00001) and 5 years(RR =1.26;95%CI: 1.15-1.37, P < 0.00001). Recurrence rate was significantly reduced by cellular immunotherapy at 6 mo(RR = 0.50;95%CI: 0.36-0.69, P < 0.0001) and 1 year(RR = 0.82;95%CI: 0.75-0.89, P < 0.00001). Adverse effect assessment addressed that immunotherapy with DCs and/or CIKs was accepted as a safe,feasible *** Combination immunotherapy with DCs, CIKs and DC/CIK with various routine treatments for HCC was evidently suggested to improve patients’ prognosis by increasing overall survival and reducing cancer recurrence.

关键词： Hepatocellular carcinoma Immunotherapy Dendritic cells Cytokine-induced killer cells

Novel mutation in ODF2 causes multiple morphological abnormalities of the sperm flagella in an infertile male

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Asian Journal of Andrology 2022年第5期24卷 463-472页

作者： Zi-Jue Zhu Yi-Zhou wang xiao-bo wang Chen-Cheng Yao Liang-Yu Zhao Zhen-bo Zhang Yu Wu Wei Chen Zheng Li Department of Andrology Urological Medical CenterShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China Department of Assisted Reproductive Technology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

Numerous genes have been associated with multiple morphological abnormalities of the sperm flagella(MMAF),which cause severe asthenozoospermia and lead to male infertility,while the causes of approximately 50%of MMAF cases remain *** reveal the genetic causes of MMAF in an infertile patient,whole-exome sequencing was performed to screen for pathogenic genes,and electron microscope was used to reveal the sperm flagellar ultrastructure.A novel heterozygous missense mutation in the outer dense fiber protein 2(ODF2)gene was detected,which was inherited from the patient’s mother and predicted to be potentially *** electron microscopy revealed that the outer dense fibers were defective in the patient’s sperm tail,which was similar to that of the reported heterozygous Odf2 mutation *** of ODF2 showed severe ODF2 expression defects in the patient’s ***,it was concluded that the heterozygous mutation in ODF2 caused MMAF in this *** evaluate the possibility of assisted reproductive technology(ART)treatment for this patient,intracytoplasmic sperm injection(ICSI)was performed,with the help of a hypo-osmotic swelling test and laser-assisted immotile sperm selection(LAISS)for available sperm screening,and artificial oocyte activation with ionomycin was applied to improve the fertilization *** ICSI cycles were performed,and live birth was achieved in the LAISS-applied cycle,suggesting that LAISS would be valuable in ART treatment for MMAF.

关键词： intracytoplasmic sperm injection laser-assisted immotile sperm selection multiple morphological abnormalities of the sperm flagella outer dense fiber protein 2(ODF2)

Permanent Magnetic Properties of Melt-Spun YCo5Cx Ribbons

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Chinese Physics Letters 2010年第6期27卷 210-212页

作者： wang Fei YAN Yu YUAN Zhou BAI Xue DU xiao-bo wang Wen-Quan SU Feng JIN Han-Min State key Laboratory for Superhard Materials and Department of Physics Jilin University Changchun 130012

Ribbons of nominal compositions YCo5 Cx （x = 0, 0.2, 0.4, 0.6） are prepared by melt spinning at surface velocities v = 5, 10, 15, 20, 25, 30 and 35 m/s. YCo5 ribbon is crystallized in a single YCo5 phase of hexagonal CaCu5 structure. A small quantity of YCoC2 phase appears in the ribbons with C addition besides the YCo5 phase. With the increase of x the lattice constant c increases and a along with the unit cell volume decreases. The largest values of iHc = 888 kA/m and （BH）max = 58.4 k Jim3 at present for the YCo5 ribbon system were obtained with x = 0.4 and v = 20 m/s. The improvement of the permanent magnetic properties is rooted in the refinement of the microstructure and the appearance of the YCoC2 phase which can act as domain wall pinning centers.

关键词： Lymphocytes Magnetic Properties Ribbons

Anisotropic Spin Cluster as a Qubit

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Communications in Theoretical Physics 2007年第7期48卷 90-92页

作者： YAN xiao-bo wang Ming-Ji Electronic Science Institute,Daqing Petroleum Institute,Daqing 163318,China Electronic Science Institute Daqing Petroleum Institute Daqing 163318 China

We study an anisotropic spin cluster of 3 spin S=1/2 particles with antiferromagnetic exchange interactionwith non-uniform coupling constants.A time-dependent magnetic field is applied to control the time evolution of *** is well known that for an odd number of sites a spin cluster qubit can be defined in terms of the ground *** universal one-qubit logic gate can be constructed from the time evolution operator of the non-autonomousmany-body system,and the six basic one-qubit gates can be realized by adjusting the applied time-dependent magneticfield.

关键词： algebraic dynamics anisotropic spin cluster universal one-qubit logic gate

Ultrasonographic evaluation of the rete testis thickness:a promising approach to differentiate obstructive from nonobstructive azoospermia

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Asian Journal of Andrology 2023年第6期25卷 725-730页

作者： Xin Li Ru-Hui Tian Peng Li Chun-xiao Li Ming-Hua Yao Chen-Cheng Yao xiao-bo wang Li-Ren Jiang Zheng Li Rong Wu Department of Ultrasound Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China Department of Andrology The Center for Men’s HealthUrologic Medical CenterShanghai Key Laboratory of Reproductive MedicineShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China Department of Pathology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

This study aimed to evaluate the ability of rete testis thickness(RTT)and testicular shear wave elastography(SWE)to differentiate obstructive azoospermia(OA)from nonobstructive azoospermia(NOA).We assessed 290 testes of 145 infertile males with azoospermia and 94 testes of 47 healthy volunteers at Shanghai General Hospital(Shanghai,China)between August 2019 and October *** testicular volume(TV),SWE,and RTT were compared among patients with OA and NOA and healthy *** diagnostic performances of the three variables were evaluated using the receiver operating characteristic *** TV,SWE,and RTT in OA differed significantly from those in NOA(all P≤0.001)but were similar to those in healthy *** with OA and NOA were similar at TVs of 9–11 cm^(3)(P=0.838),with sensitivity,specificity,Youden index,and area under the curve of 50.0%,84.2%,0.34,and 0.662(95%confidence interval[CI]:0.502–0.799),respectively,for SWE cut-off of 3.1 kPa;and 94.1%,79.2%,0.74,and 0.904(95%CI:0.811–0.996),respectively,for RTT cut-off of 1.6 *** results showed that RTT performed significantly better than SWE in differentiating OA from NOA in the TV overlap *** conclusion,ultrasonographic RTT evaluation proved a promising diagnostic approach to differentiate OA from NOA,particularly in the TV overlap range.

关键词： azoospermia differential diagnosis rete testis thickness shear wave elastography

Isolation and Expression Patterns of Rice WRKY82 Transcription Factor Gene Responsive to both Biotic and Abiotic Stresses

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Agricultural Sciences in China 2011年第6期10卷 893-901页

作者： PENG Xi-xu TANG Xin-ke ZHOU Ping-lan HU Yao-jun DENG xiao-bo HE Yan wang Hai-hua School of Life Sciences Hunan University of Science and Technology Xiangtan 411201 P.R.China

WRKY transcription factors are involved in the regulation of response to biotic and abiotic stresses in plants. A full-length cDNA clone of rice WRKY82 gene （OsWRKY82） was isolated from a cDNA library generated from leaves infected by Magnaporthe grisea. OsWRKY82 contained an entire open reading frame in length of 1 701 bp, and was predicted to encode a polypeptide of 566 amino acid residues consisting of two WRKY domains, each with a zinc finger motif of C2H2, belonging to the WRKY subgroup I. OsWRKY82 shared high identity at the amino acid level with those from Sorghum bicolor, Hordeum vulgare, and Zea mays. The transcript level of OsWRKY82 was relatively higher in stems, leaves, and flowers, and less abundant in grains. It was induced by inoculation with M. grisea and Rhizoctonia solani. However, the inducible expression in incompatible rice-M. grisea interactions was earlier and greater than that in compatible interactions. The expression of OsWRKY82 was up-regulated by methyl jasmonate and ethephon, whereas salicylic acid exerted no effects on its expression. Moreover, OsWRKY82 exhibited transcriptional activation ability in yeast. Additionally, OsWRKY82 transcripts could be induced by wounding and heat shocking, but not by abscisic acid, cold, high salinity and dehydration. By contrast, gibberellin suppressed the expression of OsWRKY82. These indicate that OsWRKY82 is a multiply stress-inducible gene responding to both biotic and abiotic stresses, and may be involved in the regulation of defense response to pathogens and tolerance against abiotic stresses by jasmonic acid/ethylene-dependent signaling pathway.

关键词： WRKY transcription factor biotic stress abiotic stress gene expression Oryza sativa

Validity and reliability testing of the Chinese (mainland) version of the 39-item Parkinson's Disease Questionnaire (PDQ-39)

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第7期11卷 531-538页

作者： Wei LUO xiao-hong GUI bo wang Wen-ying ZHANG Zhi-yuan OUYANG Yi GUO Bao-rong ZHANG Mei-ping DING Department of Neurology the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

The 39-item Parkinson's Disease Questionnaire (PDQ-39) has been tested in many languages, but not in Chinese mainland. We aimed to assess the Chinese (mainland) version of the PDQ-39. Seventy-one subjects with Parkinson's disease (PD) completed the PDQ-39 and the Medical Outcomes Study 36-item Short Form Health Survey (SF-36). All subjects were retested with the PDQ-39 a week later. The united Parkinson's disease rating scale (UPDRS) and the Hoehn and Yahr (H & Y) scale were also used to evaluate the subjects. Reliability was assessed by Cron- bach's α and intra-class correlation coefficient (ICC). Validity was examined in terms of agreement with SF-36, UPDRS, and H & Y scales. The Chinese (mainland) version of the PDQ-39 demonstrated acceptable reliability (Cronbach's α: 0.84-0.88; ICC: 0.56-0.82). The item-total correlations (0.33-0.88) and scaling success rates (77.56%) indicated satisfactory convergent and discriminant validity of the PDQ-39 items. The correlations between related constructs of the PDQ-39 and UPDRS (r=0.44-0.68) and between those of the PDQ-39 and SF-36 (r=(-0.46)-(-0.69)) were all statistically significant (Pbodily discomfort, all other dimensions of the PDQ-39 significantly discriminated patients at different H & Y stages indicated by the H & Y scale. Although our observations indicate that some problematic subscales of this version of the PDQ-39 could be improved upon, this study suggests acceptable reliability and validity of the Chinese (mainland) version of the PDQ-39.

关键词： 39-item Parkinson’s Disease Questionnaire (PDQ-39) Quality of life Validity Reliability

Novel deletion mutations of the PIH1D3 gene in an infertile young man with primary ciliary dyskinesia and his cousin with Kartagener’s syndrome

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Asian Journal of Andrology 2021年第3期23卷 330-332页

作者： Chuan Huang Na-Chuan Liu xiao-bo wang Ben-Hong Gu Jian-Xiong Zhang Li-Zhang Zheng Li Department of Andrology Center for Men's HealthShanghaiChina Department of ART Institute of Urologic Medical CenterShanghai General HospitalShanghaiKey Lab of Reproductive MedicineShanghai Jiao Tong UniversityShanghai 200080China The Human Sperm Bank Reproductive and Genetic Hospital of CITIC-XiangyaChangsha 410000China Department of Urology Tongren HospitalShanghai Jiao Tong UniversitySchool of MedicineShanghai 200080China.

Dear Editor,Male infertility is defined as the inability to achieve pregnancy in a fertile female partner even after 12 months of unprotected *** humans,it accounts for 40%-50%of cases of infertility,1 and it occurs most often due to problems with sperm production or sperm *** infertility is commonly due to deficiencies in semen,and semen quality is used as a surrogate measure of male *** ciliary dyskinesia(PCD)is a rare cause of male infertility.2,3 It is an autosomal recessive genetic condition that causes abnormal function of *** are microscopic finger-like projections on the surface of the cells.

关键词： partner protected cilia