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Degrees of Diaphragma Sellae Descent during Transsphenoidal Pituitary Adenoma Resection:Predictive Factors and Effect on Outcome

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Current Medical Science 2018年第5期38卷 888-893页

作者： Ahmed Abdelmaksoud Peng FU Osamah Alwalid Ahmed Elazab Ahmed Zalloom Wei XIANG xiao-bing jiang Hong-yang ZHAO Department of Neurosurgery Union HospitalTongji Medical CollegeHuazhong University of Science and Technology Wuhan 430022China Department of Radiology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China School of Biomedical Engineering Health Science CenterShenzhen UniversityShenzhen 518060China Computer Science Department Misr Higher Institute for Commerce and ComputersMansoura 11001Egypt

This study is aimed to classify degrees of diaphragma sellae (DS) descent into sella turcica according to the surgical field block caused by the descent and to construct predictive imaging criteria for the degree of descent,and in addition,to determine whether there is any correlation between the degree of DS descent and the operative outcome (in the form of cerebrospinal fluid leak and/or presence of residual tumor).Totally,72 patients were enrolled in our *** clinical and radiological data as well as the high definition videos of operations were retrospectively *** degree of DS descent during the operation was classified into five degrees according to surgical field block caused by the *** investigated the correlation between these five degrees and the clinical findings,radiological findings as well as the surgical *** found that the most important determining factors of DS descent degree were the volume and the height of the tumor portion above diaphragma *** the other hand,the total tumor volume,the maximum tumor height and the morphological pattern according to Wilson's system (modified from Hardy) had no statistically significant correlation with DS degree of *** of residual tumor on postoperative magnetic resonance images was significantly correlated with Wilson's classification and with supradiaphragmatic tumor *** the other hand,cerebrospinal fluid leak showed no statistically significant difference between variable degrees of DS *** data of the tumor portion above the diaphragma opening are more important than morphological data for prediction of surgical field block caused by descended *** DS prolapse significantly increases the difficulty of the operative procedure,residual tumor presence is mainly dependent on morphological classification,especially cavernous sinus invasion.

关键词： diaphragma sellae pituitary macroadenoma transsphenoidal surgery cerebrospinal fluid leak

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Nanobody-based bispecific T-cell engager (Nb-BiTE): a new platform for enhanced T-cell immunotherapy

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Signal Transduction and Targeted Therapy 2023年第10期8卷 4444-4447页

作者： xiao-mei Yang Xuan-dong Lin Wei Shi Shen-xia Xie Xia-ning Huang Shi-hua Yin xiao-bing jiang Bruce D.Hammock Zhi Ping Xu xiao-ling Lu Guangxi Key Laboratory of Nanobody Research Guangxi Nanobody Engineering Research CenterCollege of StomatologyHospital of StomatologyLaboratory Animal CenterSchool of Basic Medical SciencePharmaceutical CollegeGuangxi Medical UniversityNanning CityGuangxi 530021P.R.China Department of Neurosurgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan CityHubei 430022P.R.China Department of Entomology and Nematology UCD Comprehensive Cancer CenterUniversity of CaliforniaDavisCA 95616USA Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbaneQLD 4072Australia Institute of Biomedical Health Technology and Engineering and Institute of Systems and Physical Biology Shenzhen Bay LaboratoryShenzhen 518107P.R.China

A novel bispecific T-cell engager(BiTE)has been developed as an efficient immunotherapeutic molecule specifically bringing the T-cell and the tumor target together for enhanced *** general BiTE construct consists of two single-chain variable antibody fragments(scFvs)targeting a tumor-associated antigen(TAA)and a T-cell marker in *** binding of BiTEs to tumor antigens induces immediate T-cells’cytotoxicity against tumor cells without involving any typical costimulatory signals,specific TCR and MHC recognition.

关键词： immunotherapy tumor cytotoxicity

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Control strategy for sulfur dioxide and acid rain pollution in China

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Journal of Environmental Sciences 2000年第4期12卷 385-393页

作者： HAO Ji ming, WANG Shu xiao, LIU bing jiang, HE Ke bin (Department of Environmental Science and Engineering, Tsinghua University, Beijing 100084, China.E\|mail:hjm\|den@***) 清华大学北京 100084

Several factors, namely, coal dominated primary energy mix, extensive economic development mode, inefficient energy utilization, and the imperfect environmental regulations, result in the serious urban sulfur dioxide pollution and large scale sulfate type acid precipitation in China. In 1995, China′s sulfur dioxide emissions reached 23.70 Mt, and the areas affected by acid rain accounted for 40% of the territory. Chinese government accords considerable importance to the sulfur dioxide and acid rain contamination. New sets of environmental friendly policies have been promulgated. But enforcement of laws and regulations on SO 2 emissions need to be further improved and broadened, especially those respond to market conditions. This paper focuses particular attention on the analysis of strategy, policies, and national actions which had or should be taken against sulfur dioxide emissions nationwide to achieve the environmental targets, on the basis of which gives the technical options in future.

关键词： sulfur dioxide acid rain control

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Electrode/Electrolyte Optimization‑Induced Double‑Layered Architecture for High‑Performance Aqueous Zinc‑(Dual)Halogen Batteries

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Nano-Micro Letters 2025年第3期17卷 121-137页

作者： Chengwang Zhou Zhezheng Ding Shengzhe Ying Hao jiang Yan Wang Timing Fang You Zhang bing Sun xiao Tang xiaomin Liu School of Textiles and Clothing School of Chemistry and Chemical EngineeringQingdao UniversityQingdao 266071ShandongPeople’s Republic of China Centre for Clean Energy Technology School of Mathematical and Physical SciencesFaculty of ScienceUniversity of Technology SydneyUltimoNSW 2007Australia School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007HenanPeople’s Republic of China

Aqueous zinc-halogen batteries are promising candidates for large-scale energy storage due to their abundant resources,intrinsic safety,and high theoretical ***,the uncontrollable zinc dendrite growth and spontaneous shuttle effect of active species have prohibited their practical ***,a double-layered protective film based on zinc-ethylenediamine tetramethylene phosphonic acid(ZEA)artificial film and ZnF2-rich solid electrolyte interphase(SEI)layer has been successfully fabricated on the zinc metal anode via electrode/electrolyte synergistic *** ZEA-based artificial film shows strong affinity for the ZnF2-rich SEI layer,therefore effectively suppressing the SEI breakage and facilitating the construction of double-layered protective film on the zinc metal *** double-layered architecture not only modulates Zn2+flux and suppresses the zinc dendrite growth,but also blocks the direct contact between the metal anode and electrolyte,thus mitigating the corrosion from the active *** employing optimized metal anodes and electrolytes,the as-developed zinc-(dual)halogen batteries present high areal capacity and satisfactory cycling *** work provides a new avenue for developing aqueous zinc-(dual)halogen batteries.

关键词： Zn metal anodes Double-layered protective film Electrode/electrolyte optimization Aqueous zinc-(dual)halogen batteries

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Peripheral blood RNA biomarkers can predict lesion severity in degenerative cervical myelopathy

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Neural Regeneration Research 2025年第6期20卷 1764-1775页

作者： Zhenzhong Zheng Jialin Chen Jinghong Xu Bin jiang Lei Li Yawei Li Yuliang Dai bing Wang Department of Spine Surgery The Second Xiangya Hospital of Central South UniversityChangshaHunan ProvinceChina

Degenerative cervical myelopathy is a common cause of spinal cord injury,with longer symptom duration and higher myelopathy severity indicating a worse *** numerous studies have investigated serological biomarkers for acute spinal cord injury,few studies have explored such biomarkers for diagnosing degenerative cervical *** study involved 30 patients with degenerative cervical myelopathy(51.3±7.3 years old,12 women and 18 men),seven healthy controls(25.7±1.7 years old,one woman and six men),and nine patients with cervical spondylotic radiculopathy(51.9±8.6 years old,three women and six men).Analysis of blood samples from the three groups showed clear differences in transcriptomic *** analysis identified 128 differentially expressed genes that were enriched in patients with neurological *** least absolute shrinkage and selection operator analysis,we constructed a five-gene model(TBCD,TPM2,PNKD,EIF4G2,and AP5Z1)to diagnose degenerative cervical myelopathy with an accuracy of 93.5%.One-gene models(TCAP and SDHA)identified mild and severe degenerative cervical myelopathy with accuracies of 83.3%and 76.7%,*** of two immune cell types(memory B cells and memory-activated CD4^(+)T cells)predicted levels of lesions in degenerative cervical myelopathy with 80%*** results suggest that peripheral blood RNA biomarkers could be used to predict lesion severity in degenerative cervical myelopathy.

关键词： biomarkers candidate genes degenerative cervical myelopathy gene expression analysis immune cell types neurological disabilities peripheral blood RNA profiles spinal cord injury

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基于信息融合的预装式变电站健康状态评估

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电力系统保护与控制 2017年第14期45卷 85-91页

作者：苗红霞萧旋旋江冰胡钢河海大学物联网工程学院江苏常州213000

预装式变电站将气体绝缘组合电器设备(GIS)、变压器、低压开关柜和二次设备等作为模块集成在一组外壳内,使得整个变电站成为了一个产品,故对预装式变电站的整站状态评估成为可能。提出了基于信息融合的评估方法。首先用多层模糊综合评... 详细信息

预装式变电站将气体绝缘组合电器设备(GIS)、变压器、低压开关柜和二次设备等作为模块集成在一组外壳内,使得整个变电站成为了一个产品,故对预装式变电站的整站状态评估成为可能。提出了基于信息融合的评估方法。首先用多层模糊综合评价法、BP神经网络和灰色关联法三种方法对预装式变电站中的GIS、变压器、低压开关柜和二次设备四大模块进行状态评估。再利用DS合成法则将三种方法得出的评估结果进行融合,分别得出各个模块的综合评估结果。最后将这四大模块作为预装式变电站的评价因素,使用单层模糊综合评价法对整站进行状态评估。仿真结果表明,该方法能正确评估出预装式变电站整站的健康状态。

关键词：预装式变电站状态评估信息融合模糊综合评判神经网络灰色关联

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Double-balloon enteroscopy in detecting small intestinal bleeding

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Chinese Medical Journal 2005年第21期118卷 1834-1837页

作者： ZHI Fa-chao xiao bing jiang Bo WAN Tian-mo GUO Yu ZHOU Dan WANG Li-hui CHEN Jin-feng XIE Lu PAN De-shou ZHOU Dian-yuan Institute of Digestive Medicine Nanfang Hospital Southern Medical University Guangzhou 510515 China

Digestive tract hemorrhage is a common disease of the digestive system, but about 0. 4% -5% intestinal bleeding can not be detected with gastroscope or colonscope. 1 Since the intestine is long, tortuous, far away from both ends of the digestive tract and unfixed in position, clinical diagnosis of the bleeding is relatively difficult. Yamamoto and Sugano2 reported the clinical application of double-balloon enteroscope at American DDW in 2003. Since this new instrument can help to observe the entire intestine, obtain biopsy sample, mark lesions and carry out treatments, it has drawn the attention of researchers all over the world. In 2003, we successfully used Japanese Fujinon double-balloon enteroscope in detecting suspected intestinal hemorrhage in 57 patients.

关键词： digestive tract bleeding small intestine enteroscope double-balloon

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Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang Chung Hsien Wu Jiwen jiang Fei Long Liyuan Han Qifeng Han Yi‑bing Cheng Yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

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Separation of the ionospheric and thermospheric contributions in the data from the Triple Ionosophere Photo Meter onboard the Feng-Yun 3E satellite

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Science China Earth Sciences 2025年第1期68卷 172-184页

作者： Fang jiang Tian MAO Jin-Song WANG Xiu-Qing HU xiao-Xin ZHANG Liping FU Nan JIA Tianfang WANG National Space Science Center Chinese Academy of Sciences Beijing Key Laboratory of Space Environment Exploration Key Laboratory of Environmental Space Situation Awareness Technology National Satellite Meteorological Center China Meteorological Administration

The Triple Ionosphere Photo Meter （TRIPM） is a far ultraviolet nadir-view photometer that is onboard the secondgeneration,polar-orbiting Chinese meteorological satellite Feng-Yun 3E （FY-3E）,which was launched on July 5,*** has three channels,and each is used to measure different types of emissions:（1） 135.6 nm airglow produced by the recombination of the O+ions and electrons in the absence of sunlight （nighttime channel）;（2） 135.6 nm airglow from the OI when sunlight is present （daytime/dusk-dawn 135.6 nm channel）;and （3） Airglow in the N2LBH of the TRIPM （daytime/dusk-dawn N2LBH channel）.FY-3E is a satellite operating in the early morning ***,the data are mostly distributed on the dawndusk side or at times when the solar zenith angle is relatively *** this study,combined with simulation calculations,the data are *** further explore the application value of the data products,a model is used to separate the ionospheric radiative recombination contribution from the thermosphere photoelectron impact excitation contribution in the data from the daytime/dusk-dawn 135.6 nm *** approach not only improves the accuracy of O/N2derived from the 135.6 nm channel and N2LBH channel but also provides the ionospheric 135.6 nm radiance at the same time as the *** results show that the 135.6 nm radiance originating from the combination of O+and electrons extracted from the measurement data exhibits similar equatorial anomaly peak structure characteristics and seasonal variations as the corresponding GPS total electron content （TEC） *** the other hand,the separated 135.6 nm radiance generated from the thermosphere photoelectron collision excitation does not contain radiative recombination contributions;thus,the ionosphere influence is greatly avoided when the O/N2is obtained.

关键词： Far ultraviolet 135.6 nm emission intensity Photoelectron impact excitation Radiative recombination excitation

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Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches

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Science China Life Sciences 2025年第1期68卷 232-248页

作者： Yaohan jiang xiao Chen Chundi Wang Liping Lyu Saleh A.Al-Farraj Naomi A.Stover Feng Gao Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity Ocean University of China Marine College Shandong University Zoology Department College of ScienceKing Saud University Department of Biology Bradley University Laboratory for Marine Biology and Biotechnology Qingdao Marine Science and Technology Center

Sexual reproduction first appeared in unicellular protists and has continued to be an essential biological process in almost all *** protists, which contain both germline and somatic genomes within a single cell, have evolved a special form of sexual reproduction called conjugation that involves mitosis, meiosis, fertilization, nuclear differentiation, genome rearrangement, and the development of unique cellular structures. The molecular basis and mechanisms of conjugation vary dramatically among ciliates, and many details of the process and its regulation are still largely unknown. In order to better comprehend these processes and mechanisms from an evolutionary perspective, this study provides the first comprehensive overview of the transcriptome and proteome profiles during the entire life cycle of the newly-established marine model ciliate Euplotes vannus. Transcriptome analyses from 14 life cycle stages(three vegetative stages and 11 sexual stages) revealed over 26,000 genes that are specifically expressed at different stages, many of which are related to DNA replication,transcription, translation, mitosis, meiosis, nuclear differentiation, and/or genome rearrangement. Quantitative proteomic analyses identified 338 proteins with homologs associated with conjugation and/or somatic nuclear development in other ciliates, including dicer-like proteins, Hsp90 proteins, RNA polymerase Ⅱ and transcription elongation factors, ribosomal-associated proteins, and ubiquitin-related proteins. Four of these homologs belong to the PIWI family, each with different expression patterns identified and confirmed by RT-qPCR,which may function in small RNA-mediated genome rearrangement. Proteins involved in the nonhomologous end-joining pathway are induced early during meiosis and accumulate in the developing new somatic nucleus, where more than 80% of the germline sequences are eliminated from the somatic genome. A number of new candidate genes and proteins likely t

关键词： sexual reproduction transcriptomic proteomic genome rearrangement PIWI NHEJ

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