检索结果-南通市图书馆

Associations between residence and cognitive function among Chinese older adults: the mediating role of leisure activity

在线全文

学校读者我要写书评

暂无评论

Medical Data Mining 2024年第3期7卷 46-52页

作者： xiao-Dong Leng Wen-Ping zeng Mao-Rui Qian School of Public Health Chongqing Medical UniversityChongqing 401331China

Background:Cognitive function is a current research hotspot,residence may be related to differences in cognitive function,and the mediating role of leisure activities are limited in Chinese *** study used leisure activities as a mediating variable to investigate the mediating role of leisure activity between place of residence(city-town-rural)and cognitive function among Chinese older,this is where the innovation of the article comes ***:Using cross-sectional data from the 2018 Chinese Longitudinal Healthy Longevity Survey,Pearson correlation analyses were employed to examine the relationships among various *** analyses were conducted using the SPSS PROCESS macro program,version 3.5,written by Hayes,to explore the mediating effects of leisure activity between place of residence and cognitive function in older ***:A total of 10955 older adults were included in this study,with a mean age of(84.23±11.57)*** them,2739(24.8%)lived in the city,3627(33.1%)in town,and 4615(42.1%)in rural areas;their leisure activity score was(5.34±3.77),and their cognitive function score was(24.69±6.65).Place of residence,leisure activities,and cognitive function were significantly correlated(P<0.01).Using city as a reference,place of residence is negatively associated with cognitive function,and place of residence not only had a direct effect on cognitive function in older adults:town-cognitive function(effect=–0.399;95%confidence interval(CI)=(–0.685,–0.113));rural-cognitive function(effect=–0.42;95%CI=(–0.698,–0.141)).There were also indirect effects on cognitive function through the pathway of leisure activity:town-leisure activity-cognitive function(effect=–0.17;95%CI=(–0.246,–0.1)),rural-leisure activity-cognitive function(effect=–0.199;95%CI=(–0.272,–0.13)).Conclusion:Leisure activities play a partially mediating role between the impact of place of residence and cognitive function in Chinese older adults,and it is vital to pay atte

关键词： residence leisure activity cognitive function intermediary role older adults

Effective time, correction speed and termination time of hemiepiphysiodesis in children

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2024年第1期15卷 1-10页

作者： Jian-Fa zeng Yu-Yin Xie Can Liu Zhen-Qi Song Zheng Xu Zhong-Wen Tang Jie Wen Sheng xiao Department of Pediatric Orthopedics Hunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 410013Hunan ProvinceChina Department of Anatomy Hunan Normal University school of MedicineChangsha 410003Hunan ProvinceChina

In children with asymmetric growth on the medial and lateral side of limbs,if there still remains growth potential,the guided growth technique of hemiepiphysiodesis on one side of the epiphysis is recognized as a safe and effective ***,when the hemi-epiphysiodesis start to correct the deformities,how many degrees could hemi-epiphysiodesis bring every month and when to remove the hemi-epiphysiodesis implant without rebound phenomenon are still on *** article reviews the current studies focus on the effective time,correction speed and termination time of hemi-epiphysiodesis.

关键词： Hemi-epiphysiodesis Percutaneous epiphysiodesis Transphyseal screws Eight plate

Roles of combined femoral and acetabular anteversion in pathological changes of hip dysplasia and hip reconstructive surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2024年第5期15卷 390-399页

作者： Can Liu Zheng Xu Jian-Fa zeng Zhen-Qi Song Yu-Yin Xie Zhong-Wen Tang Jie Wen Sheng xiao Department of Anatomy Hunan Normal University School of MedicineChangsha 410003Hunan ProvinceChina Department of Pediatric Orthopedics Hunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 410013Hunan ProvinceChina

Combined femoral and acetabular anteversion is the sum of femoral and acetabular anteversion,representing their morphological relationship in the axial *** with the increasing understanding of hip dysplasia in recent years,numerous scholars have confirmed the role of combined femoral and acetabular anteversion in the pathological changes of hip *** present,the reconstructive surgery for hip dysplasia includes total hip replacement and redirectional hip preservation *** an important surgery index,combined femoral and acetabular anteversion have a crucial role in these ***,we discuss the role of combined femoral and acetabular anteversion in pathological changes of hip dysplasia,total hip replacement,and redirectional hip preservation surgery.

关键词： Combined anteversion Femoral anteversion Acetabular anteversion Hip dysplasia Hip preservation surgery Total hip replacement

Accurate prediction of myopic progression and high myopia by machine learning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Precision Clinical Medicine 2024年第1期7卷 14-20页

作者： Jiahui Li Simiao zeng Zhihuan Li Jie Xu Zhuo Sun Jing Zhao Meiyan Li Zixing Zou Taihua Guan Jin zeng Zhuang Liu Wenchao xiao Ran Wei Hanpei Miao Ian Ziyar Junxiong Huang Yuanxu Gao Yangfa zeng Xing-Tao Zhou Kang Zhang Guangzhou Women and Children's Medical Center Guangzhou Medical UniversityGuangzhou 510120China Guangzhou National Laboratory Guangzhou 510o0oChina Zhuhai International Eye Center of the First Affiliated Hospital of Faculty of Medicine Macao University of Science and TechnologyZhuhai 519000China Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing 100069China Key Laboratory of Myopia Ministry of HealthShanghai Key Laboratory of Visual Impairment and RestorationDepartment of OphthalmologyEye InstituteEye and EarNoseand Throat HospitalFudan UniversityShanghai 200031China DongguanPeople's Hospital The First School of Clinical MedicinelSouthern Medical UniversityDongguan 523059China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060China Wenzhou Eye Hospital and Institute for Advanced Study on Eye Health and Diseases Wenzhou Medical UniversityWenzhou 32500oChina

Background Myopia is a leading cause of visual impairment in Asia and ***,accurately predicting the progression of myopia and the high risk of myopia remains a *** study aims to develop a predictive model for the development of *** We first retrospectively gathered 612530 medical records from five independent cohorts,encompassing 227543 patients ranging from infants to young ***,we developed a multivariate linear regression algorithm model to predict the progression of myopia and the risk of high *** The model to predict the progression of myopia achieved an R^(2) value of 0.964 vs a mean absolute error(MAE)of 0.119D[95%confidence interval(CI):0.119,1.146]in the internal validation *** demonstrated strong generalizability,maintaining consistent performance across external validation sets:R^(2)=0.950 vs MAE=0.119D(95%CI:0.119,1.136)in validation study 1,R^(2)=0.950 vs MAE=0.121D(95%CI:0.121,1.144)in validation study 2,and R^(2)=0.806 vs MAE=−0.066D(95%CI:−0.066,0.569)in the Shanghai Children Myopia *** the Beijing Children Eye Study,the model achieved an R^(2) of 0.749 vs a MAE of 0.178D(95%CI:0.178,1.557).The model to predict the risk of high myopia achieved an area under the curve(AUC)of 0.99 in the internal validation set and consistently high area under the curve values of 0.99,0.99,0.96 and 0.99 in the respective external validation *** Our study demonstrates accurate prediction of myopia progression and risk of high myopia providing valuable insights for tailoring strategies to personalize and optimize the clinical management of myopia in children.

关键词： myopia progression machine learning prevention precision medicine

Integrated ribosome and proteome analyses reveal insights into sevoflurane-induced long-term social behavior and cognitive dysfunctions through ADNP inhibition in neonatal mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2024年第3期45卷 663-678页

作者： Li-Rong Liang Bing Liu Shu-Hui Cao You-Yi Zhao Tian zeng Mei-Ting Zhai Ze Fan Dan-Yi He San-Xin Ma xiao-Tong Shi Yao Zhang Hui Zhang State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration National Clinical Research Center for Oral DiseasesShaanxi Engineering Research Center for Dental Materials and Advanced ManufactureDepartment of AnesthesiologySchool of StomatologyAir Force Medical UniversityXi’anShaanxi 710032China Department of Anesthesiology 986th Air Force HospitalAir Force Medical UniversityXi’anShaanxi 710032China

A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive ***,an active fragment of the activity-dependent neuroprotective protein(ADNP),has been implicated in social and cognitive ***,the potential of davunetide to attenuate social deficits following sevoflurane exposure and the underlying developmental mechanisms remain poorly *** this study,ribosome and proteome profiles were analyzed to investigate the molecular basis of sevoflurane-induced social deficits in neonatal *** neuropathological basis was also explored using Golgi staining,morphological analysis,western blotting,electrophysiological analysis,and behavioral *** indicated that ADNP was significantly down-regulated following developmental exposure to *** adulthood,anterior cingulate cortex(ACC)neurons exposed to sevoflurane exhibited a decrease in dendrite number,total dendrite length,and spine ***,the expression levels of Homer,PSD95,synaptophysin,and vglut2 were significantly reduced in the sevoflurane ***-clamp recordings indicated reductions in both the frequency and amplitude of miniature excitatory postsynaptic currents(mEPSCs).Notably,davunetide significantly ameliorated the synaptic defects,social behavior deficits,and cognitive impairments induced by *** analysis revealed that loss of ADNP led to dysregulation of Ca^(2+)activity via the Wnt/β-catenin signaling,resulting in decreased expression of synaptic *** of Wnt signaling was restored in the davunetide-treated ***,ADNP was identified as a promising therapeutic target for the prevention and treatment of neurodevelopmental toxicity caused by general *** study provides important insights into the mechanisms underlying social and cognitive disturbances caused by sevoflurane exposure in neonatal

关键词： Davunetide Sevoflurane Abnormal social behaviors ADNP Neurotoxicity

Electromagnetic dispersion characteristics of a high energy electron beam guided with an ion channel

在线全文

学校读者我要写书评

暂无评论

Plasma Science and Technology 2017年第2期19卷 20-27页

作者：肖集雄曾中王之江夏冬辉刘昌海 Institute of fusion and plasma research Huazhong University of Science and TechnologyWuhan 430074People's Republic of China

Taking self-fields into consideration, dispersion properties of two types of electromagnetic modes for a high energy electron beam guided with an ion channel are investigated by using the linear perturbation theory. The dependences of the dispersion frequencies of electromagnetic waves on the electron beam radius, betatron frequency and boundary current are revealed. It is found that the electron beam radius and betatron frequency have different influences on the electromagnetic waves dispersion behavior by compared with the previous works. As the boundary current is taken into account, the TM modes will have two branches and a lowfrequency branch emerged as the new branch in strong ion channel case. This new branch has similar dispersion behavior to the betatron modes. For TE modes, there are two branches and they have different dispersion behaviors in strong ion channel case. However, in weak ion channel case, the dispersion behaviors for both of the low frequency and high frequency branches are similar.

关键词： dispersion behavior electromagnetic eigenmodes betatron oscillation ion channel

Two-dimensional atomically thin Pt layers on MXenes: The role of electronic effects during catalytic dehydrogenation of ethane and propane

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第3期17卷 1251-1258页

作者： Zhe Li Tobias K.Misicko Fan Yang xiaopeng Liu Zhenwei Wu xiaoyang Gao Tao Ma Jeffrey T.Miller Daniela S.Mainardi Collin D.Wick Zhenhua zeng Yang xiao Yue Wu Department of Chemical and Biological Engineering Iowa State University618 Bissell RoadAmesIA 50011USA Institute for Micromanufacturing Louisiana Tech University505 Tech DriveRustonLA 71272USA Davidson School of Chemical Engineering Purdue University480 Stadium Mall DriveWest LafayetteIN 47907USA Michigan Center for Materials Characterization University of Michigan2800 Plymouth RdAnn Arbor MI 48109USA College of Engineering and Science Louisiana Tech UniversityRustonLA 71272USA

Atomically thin Pt nanolayers were synthesized on the surface of Mo2TiC2 MXenes and used for the catalytic dehydrogenation of ethane and propane into ethylene and propylene,two important chemicals for the petrochemical *** compared with Pt nanoparticles,the atomically thin Pt nanolayer catalyst showed superior coke-resistance(no deactivation for 24 h),high activity(turnover frequencies(TOFs)of 0.4–1.2 s^(-1)),and selectivity(>95%)toward ethylene and *** unique Pt nanolayer has a similar geometric surface to Pt nanoparticles,enabling the investigations of the electronic effect on the catalytic performance,where the geometric effect is *** is found that the electronic effect plays a critical role in dehydrogenative product selectivity and catalyst *** metal–support interaction is found dependent on the substrate and metal components,providing wide opportunities to explore high-performance MXene-supported metallic catalysts.

关键词： MXene catalysis alkane dehydrogenation nanolayers

Changes of Terrestrial Water Storage in the Yellow River Basin Under Global Warming

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Tropical Meteorology 2024年第2期30卷 132-148页

作者：曾昕瑞管晓丹陈涵魏志敏王国栋 Collaborative Innovation Center for Western Ecological Safety College of Atmospheric SciencesLanzhou UniversityLanzhou 730000 China

The increasing temperature in the Yellow River Basin has led to a rapid rise in the melting level height,at a rate of 5.98 m yr^(-1)during the cold season,which further contributes to the transition from snowfall to rainfall *** 1979 and 2020,there has been a decrease in snowfall in the Yellow River Basin at a rate of-3.03 mm dec^(-1),while rainfall has been increasing at a rate of 1.00 mm dec^(-1).Consequently,the snowfall-to-rainfall ratio(SRR)has *** directly replenishes terrestrial water storage(TWS)in solid form until it melts,while rainfall is rapidly lost through runoff and evaporation,in addition to infiltrating underground or remaining on the ***,the decreasing SRR accelerates the depletion of water *** to the surface water balance equation,the reduction in precipitation and runoff,along with an increase in evaporation,results in a decrease in TWS during the cold season within the Yellow River *** addition to climate change,human activities,considering the region's dense population and extensive agricultural land,also accelerate the decline of ***,irrigation accounts for the largest proportion of water withdrawals in the Yellow River Basin(71.8%)and primarily occurs during the warm season(especially from June to August).The impact of human activities and climate change on the water cycle requires further in-depth research.

关键词： terrestrial water storage melting level height surface water balance human activities Yellow River Basin

Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese medicine and Western medicine

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2024年第3期11卷 313-322页

作者： Ying-Hui Jin Yan-Ping wang Ying-Lan Xie Gui-Hua Tian xiao-Yu Zhang Nan-Nan Shi Ke-Hu Yang Xin Sun Yao-Long Chen Da-Rong Wu Xin-Feng Guo Long Ge Chen Zhao Cheng Lu Yin Jiang Jing Guo Si-Yu Yan Yong-Bo wang Qiao Huang Xiang-Ying Ren Ying-Yue Rao Yun-Yun wang Meng-Qian Yuan Xian-Tao zeng Hong-Cai Shang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China China Center for Evidence Based Traditional Chinese Medicine Beijing 100029China Hubei Provincial Hospital of Traditional Chinese Medicine Wuhan 430074China Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000China China Center for Evidence-Based Medicine West China Hospital of Sichuan UniversityChengdu 610041China State Key Laboratory of Dampness Syndrome of Chinese Medicine the Second Affliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120China Evidence-based Medicine Team Guangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120China Nanjing University of Chinese Medicine Nanjing 210023China Jiangsu Province Hospital of Chinese Medicine Nanjing 210029China

Integrated traditional Chinese medicine(TCM)and Western medicine(WM)is a new medical science grounded in the knowledge bases of both TCM and WM,which then forms a unique modern medical system in *** TCM and WM has a long history in China,and has made important achievements in the process of clinical diagnosis and ***,the methodological defects in currently published clinical practice guidelines(CPGs)limit its *** organic integration of TCM and WM is a deeper integration of TCM and *** realize the progression of"integration"to"organic integration",a targeted and standardized guideline development methodology is ***,the purpose of this study is to establish a standardized development procedure for clinical practice guidelines for the organic integration of TCM and WM to promote the systematic integration of TCM and WM research results into clinical practice guidelines in order to achieve optimal results as the whole is greater than the sum of the parts.

关键词： Methodology Traditional Chinese medicine Western medicine Organic integration Clinical practice guidelines(CPGs)