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Petroleum Science 2024年第2期21卷 1369-1384页

作者： Chong-Zheng Sun Yu-Xing Li Hui Han xiao-yi geng xiao Lu College of Energy Storage Technology Shandong University of Science and TechnologyQingdao 266590ShandongChina College of Pipeline and Civil Engineering/Shandong Provincial Key Laboratory of Oil&Gas Storage and Transportation Safety China University of PetroleumQingdao 266580ShandongChina

Liquid hydrogen storage and transportation is an effective method for large-scale transportation and utilization of hydrogen energy. Revealing the flow mechanism of cryogenic working fluid is the key to optimize heat exchanger structure and hydrogen liquefaction process(LH2). The methods of cryogenic visualization experiment, theoretical analysis and numerical simulation are conducted to study the falling film flow characteristics with the effect of co-current gas flow in LH2spiral wound heat *** results show that the flow rate of mixed refrigerant has a great influence on liquid film spreading process, falling film flow pattern and heat transfer performance. The liquid film of LH2mixed refrigerant with column flow pattern can not uniformly and completely cover the tube wall surface. As liquid flow rate increases, the falling film flow pattern evolves into sheet-column flow and sheet flow, and liquid film completely covers the surface of tube wall. With the increase of shear effect of gas-phase mixed refrigerant in the same direction, the liquid film gradually becomes unstable, and the flow pattern eventually evolves into a mist flow.

关键词： Hydrogen liquefaction Spiral wound heat exchanger Flow pattern transition Falling film flow

Simulation Research on a SVPWM Control Algorithm for a Four-Leg Active Power Filter

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Journal of China University of Mining and Technology 2007年第4期17卷 590-594页

作者： ZHOU Juan WU xiao-jie geng yi-wen DAI Peng School of Information and Electrical Engineering China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China

In this paper the topology of a four-leg shunt active-power filter (APF) is given. The APF compensates har-monic and reactive power in a three-phase four-wire system. The scheme adopted for control of the four-leg active power filter,a 3-Dimensional Pulse Width Modulation (PWM) technique,is presented. The theoretical deduction of a space vector PWM (SVPWM) algorithm is given in this paper. The paper also analyzes the distribution of the volt-age-space vector of the four-leg converter in αβγ coordinates and describes methods to determine the location of the voltage-space vector and to calculate duration time. Finally,the algorithm is implemented in simulation; the results show that the total harmonic distortion (THD) of the three phase-current waveforms is reduced. The neutral wire current,after compensation,is about 0 A showing that the topology of the four-leg shunt APF is feasible and the proposed scheme is effective.

关键词： three-phase four-wire system shunt active power filter 3-Dimensional space vector PWM

Interstitial carbon induces enriched Cu^(δ+) sites in Cu_(2)O nanoparticles to facilitate CO_(2) electroreduction to C_(2+) products

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Nano Research 2024年第8期17卷 7013-7019页

作者： Haoran Wang Rongbo Sun Peigen Liu Haohui Hu Chen Ling xiao Han yi Shi Xusheng Zheng geng Wu Xun Hong Center of Advanced Nanocatalysis(CAN) Department of Applied ChemistryHefei National Laboratory for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China Sinochem Holdings Co Ltd Xiongan New AreaHebei 071700China National Synchrotron Radiation Laboratory(NSRL) University of Science and Technology of ChinaHefei 230029China

The electrochemical CO_(2) reduction reaction(CO_(2)RR)holds significant promise in advancing carbon *** catalysts for the electrochemical CO_(2)RR to multi-carbon(C_(2+))products(e.g.,C_(2)H_(4))under industrial-level current density is urgently needed and ***,we report the Cu_(2)O nanoparticles doped with interstitial carbon atoms(denoted as C-Cu_(2)O NPs)for the conversion of CO_(2) to C_(2+)*** interstitial carbon promotes the C-Cu_(2)O NPs to possess abundant unsaturated Cu–O bonds,leading to a high-density Cu^(δ+)(0<δ<1)*** obtained C-Cu_(2)O NPs exhibited significant Faradic efficiency(FE)of C_(2+) products approaching 76.9%and a partial current density reaching 615.2 mA·cm^(–2)under an industrial-level current density of 800 mA·cm^(–2).Furthermore,the efficient electrosynthesis of C_(2)H_(4) achieved an FE of 57.4%with a partial current density of 459.2 mA·cm^(–2).In situ electrochemical attenuated total reflection Fourier transform infrared spectroscopy and in situ Raman spectroscopy analyses revealed that C-Cu_(2)O NPs stabilized the intermediate*CO and facilitated C–C coupling,leading to increased selectivity towards C_(2+) products.

关键词： CO_(2) electroreduction C-C coupling interstitial carbon *CO coverage industrial-level current density

Dual‑Atom Nanozyme Eye Drops Attenuate Inflammation and Break the Vicious Cycle in Dry Eye Disease

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Nano-Micro Letters 2024年第6期16卷 439-457页

作者： Dandan Chu Mengyang Zhao Shisong Rong Wonho Jhe xiaolu Cai yi xiao Wei Zhang Xingchen geng Zhanrong Li Xingcai Zhang Jingguo Li Henan Eye Hospital Henan Provincial People’s HospitalPeople’s Hospital of Zhengzhou UniversityZhengzhou 450003People’s Republic of China Department of Ophthalmology Mass Eye and EarMass General BrighamHarvard Medical SchoolBostonMA 02114USA School of Engineering and Applied Sciences Harvard UniversityCambridgeMA 02138USA College of Chemistry Zhengzhou UniversityZhengzhou 450001People’s Republic of China

Dry eye disease(DED)is a major ocular pathology worldwide,causing serious ocular discomfort and even visual *** incidence of DED is gradually increasing with the highfrequency use of electronic *** inflammation is core cause of the DED vicious cycle,reactive oxygen species(ROS)play a pivotal role in the vicious cycle by regulating inflammation from ***,current therapies merely targeting inflammation show the failure of DED ***,a novel dual-atom nanozymes(DAN)-based eye drops are *** antioxidative DAN is successfully prepared by embedding Fe and Mn bimetallic single-atoms in N-doped carbon material and modifying it with a hydrophilic *** in vitro and in vivo results demonstrate the DAN is endowed with superior biological activity in scavenging excessive ROS,inhibiting NLRP3 inflammasome activation,decreasing proinflammatory cytokines expression,and suppressing cell ***,the DAN effectively alleviate ocular inflammation,promote corneal epithelial repair,recover goblet cell density and tear secretion,thus breaking the DED vicious *** findings open an avenue to make the DAN as an intervention form to DED and ROSmediated inflammatory diseases.

关键词： Dry eye disease DAN Dual-atom nanozyme Vicious cycle NLRP3 inflammasome Nanomedicine

Identification of different degrees of processed ginger using GC-IMS combined with machine learning

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Journal of Pharmaceutical Analysis 2024年第1期14卷 149-151页

作者： Shuang Liu Hongjing Dong Minmin Zhang Wei geng xiao Wang Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province Shandong Analysis and Test CenterQilu University of Technology(Shandong Academy of Sciences)Jinan250014China Key Laboratory for Natural Active Pharmaceutical Constituents Research in Universities of Shandong Province School of Pharmaceutical SciencesQilu University of Technology(Shandong Academy of Sciences)Jinan250014China Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University Jinan250014China

Ginger,the rhizomes of Zingiber officinale Roscoe,was a wellknown edible plant species commonly used in China,which has pungent flavor[1].Ginger has numerous chemical compounds,such as phenolic constituents,volatile compounds(VOCs),and polysaccharides[2].Among them,VOCs are considered one of the effective compounds in ginger due to their functional properties,including anti-inflammatory,antioxidant,and analgesic[3].

关键词： phenolic edible rhizome

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IPSec虚拟专用网络服务质量研究与仿真

计算机仿真 2009年第8期26卷 137-142页

作者：肖耿毅桂林师范高等专科学校物理与信息技术系广西桂林541001

IPSec虚拟专用网在使用IPSec的加密、认证和封装等功能后,将会导致其服务质量(QoS)明显下降。为研究加密和认证这两个影响最大的因素,分析了目前IPSec虚拟专用网常用的加密算法和认证算法对QoS的影响,利用OPNET仿真工具建立了IPSec虚拟... 详细信息

IPSec虚拟专用网在使用IPSec的加密、认证和封装等功能后,将会导致其服务质量(QoS)明显下降。为研究加密和认证这两个影响最大的因素,分析了目前IPSec虚拟专用网常用的加密算法和认证算法对QoS的影响,利用OPNET仿真工具建立了IPSec虚拟专用网的仿真模型,把不同组合的常用加密算法和认证算法对QoS的影响分别进行仿真,并对仿真结果做了对比分析。结果表明,在隧道方式下,采用ESP/DES/MD5算法组合的IPSec_F irewall_VPN1的QoS性能最好,而加密对QoS的影响较大。今后在网络运行过程中,可以参考仿真优化结果提高网络安全和服务质量,按需求,灵活选择,使运行达到最佳的效果。

关键词：虚拟专用网服务质量加密认证仿真

Recent progress in single crystal perovskite X-ray detectors

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Science China(Information Sciences) 2024年第3期67卷 5-19页

作者： xiao LIU Jun REN Yu-Ang CHEN Xiangshun geng Dan XIE Tian-Ling REN School of Integrated Circuits Tsinghua University Beijing National Research Center for Information Science and Technology (BNRist)

Perovskites have attracted extensive attention as radiation detection material due to their long carrier diffusion length and lifetime, high absorption coefficient, and flexible manufacturing process. Compared with polycrystalline structures, single crystal perovskites improve the performance of optoelectronic devices due to their low defect state density, better photoelectric characteristics, and chemical ***, we review the recent progress of single crystal perovskite X-ray detectors. First, we briefly introduced the basic concepts, detection mechanisms, figure of merits of perovskite X-ray detectors, and the preparation methods of single crystal perovskites. Then, we summarized the significant advancements in single crystal perovskite X-ray detectors in recent times. Finally, we discussed the critical challenges and some practicable solutions for developing high-performance X-ray detectors.

关键词： single crystal perovskites carrier transport radiation detection X-ray detectors X-ray imaging

基于SPCSE与WKELM的网络入侵检测方法研究

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计算机仿真 2022年第6期39卷 425-429页

作者：肖耿毅桂林师范高等专科学校数学与计算机技术系广西桂林541199

网络入侵检测系统是用于保护系统免受非法攻击的重要网络防御工具,网络入侵行为复杂的、冗长的特征严重影响网络入侵的检测效果。现提出一种基于稀疏主成分空间嵌入与加权核极限学习机的网络入侵检测方法。为了有效约简网络入侵数据的特... 详细信息

网络入侵检测系统是用于保护系统免受非法攻击的重要网络防御工具,网络入侵行为复杂的、冗长的特征严重影响网络入侵的检测效果。现提出一种基于稀疏主成分空间嵌入与加权核极限学习机的网络入侵检测方法。为了有效约简网络入侵数据的特征,提出一种基于稀疏主成分的特征约简的降维算法,即稀疏主成分空间嵌入算法(SPCSE)。同时,为了改进极限学习机的检测效果,提出一种加权核极限学习机算法(WKELM),它采用核函数代替包含激活函数的加权极限学习机隐层随机特征映射,有利于提高算法的非线性处理能力和鲁棒性。仿真结果显示加权核极限学习机对于网络入侵的检测精度95%,极限学习机对于网络入侵的检测精度92%,而提出的网络入侵检测方法对于网络入侵的检测精度达到98.5%,表明提出的网络入侵检测方法对于网络入侵的检测结果优于传统极限学习机以及加权核极限学习机。

关键词：稀疏主成分空间嵌入加权核极限学习机网络入侵检测

Curcumin for gastric cancer:Mechanism prediction via network pharmacology,docking,and in vitro experiments

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3635-3650页

作者： Peng-Hui Yang Ya-Nan Wei Bi-Juan xiao Si-yi Li Xin-Long Li Liang-Jun Yang Hua-Feng Pan geng-Xin Chen The Second School of Clinical Medicine Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina Department of Traditional Chinese Medicine The People's Hospital of LonghuaShenzhen 518109Guangdong ProvinceChina Department of Gastroenterology Tongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Centre for Translational Medicine The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Curcumin originates from the natural herb turmeric,and its antitumor effects have been known about for a long ***,the mechanism by which curcumin affects gastric cancer(GC)has not been *** To elucidate the potential mechanisms of curcumin in the treatment of *** Network pharmacological approaches were used to perform network analysis of *** first analyzed Lipinski’s Rule of Five for the use of *** latent targets were predicted using the PharmMapper,SwissTargetPrediction and DrugBank network *** disease targets were mined through the GeneCard,OMIM,DrugBank and TTD network ***,GO enrichment,KEGG enrichment,protein-protein interaction(PPI),and overall survival analyses were *** results were further verified through molecular docking,differential expression analysis and cell *** We identified a total of 48 curcumin-related genes with 31 overlapping GC-related *** intersection targets between curcumin and GC have been enriched in 81 GO biological processes and 22 significant *** PPI analysis,6 hub targets were identified,namely,estrogen receptor 1(ESR1),epidermal growth factor receptor(EGFR),cytochrome P450 family 3 subfamily A member 4(CYP3A4),mitogen-activated protein kinase 14(MAPK-14),cytochrome P450 family 1 subfamily A member 2(CYP1A2),and cytochrome p450 family 2 subfamily B member 6(CYP2B6).These factors are correlated with decreased survival rates among patients diagnosed with *** docking analysis further substantiated the strong binding interactions between Curcumin and the hub target *** experimental findings demonstrated that curcumin not only effectively inhibits the growth of BGC-823 cells but also suppresses their *** levels of hub targets CYP3A4,MAPK14,CYP1A2,and CYP2B6 in BGC-823 cells were significantly increased in each dose *** Curcumin can play an anti-GC role through a variety of

关键词： Curcumin Gastric cancer Network pharmacology Molecular docking Survival analysis

Rare esophageal carcinoma-primary adenoid cystic carcinoma of the esophagus: A case report

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World Journal of Clinical Cases 2024年第3期12卷 630-636页

作者： Li-Dan geng Jie Li Li Yuan xiao-Bo Du Department of Oncology Mianyang Central HospitalMianyang 621000Sichuan ProvinceChina

BACKGROUND Esophageal adenoid cystic carcinoma(EACC)is an exceedingly rare malignant tumor of the esophagus,posing significant challenges in the *** SUMMARY This report detailed the case of a 72-year-old male whose diagnosis of EACC was confirmed through postoperative histopathological *** patient underwent thoracoscopy-assisted radical resection of the esophageal tumor,coupled with lymph node *** findings revealed an adenoid cystic carcinoma infiltrating the entire layer of the muscularis propria,locally extending into the outer membrane of the esophageal fiber,involving the cardia and exhibiting no lymph node *** patient’s condition was classified as primary EACC,T3N0M0,per the American Joint Committee on Cancer(2017;8th edition).One month after surgery,the patient received postoperative adjuvant radiation *** In addressing the rarity and high potential for biopsy misdiagnosis of EACC,this study delved into its diagnostic methods and treatment.

关键词： Esophageal adenoid cystic carcinoma Malignant tumor Lymph node dissection Adjuvant radiation therapy Misdiagnosis Case report