检索结果-南通市图书馆

Observation and measurement of applied anatomical features for thoracic intervertebral foramen puncture on computed tomography images

引用

World Journal of Clinical Cases 2021年第18期9卷 4607-4616页

作者： Ran Wang Wei-Wei Sun Ying Han xiao-xue fan xue-Qin Pan Shi-Chong Wang Li-Juan Lu Department of Pain Management Nanjing Drum Tower HospitalClinical College of Xuzhou Medical UniversityNanjing 210008Jiangsu ProvinceChina Department of Pain Management Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210008Jiangsu ProvinceChina

BACKGROUND Thoracic intervertebral foramen puncture is the key step for interventional therapy on the thoracic nerve roots or dorsal root *** anatomical features of the thoracic spine are complex,and puncture injury to the pleura,blood vessels,spinal cord,and other tissues may cause serious *** spatial anatomical characteristics and related parameters for thoracic intervertebral foramen puncture remain poorly *** To observe and summarize the spatially applied anatomical characteristics for intervertebral foramen puncture on different vertebral *** A total of 88 patients(41 males and 47 females)who underwent thoracic minimally invasive interventional treatment at Nanjing Drum Tower Hospital from January 2019 to June 2020 were *** tomography images of 167 thoracic vertebral segments scanned in the prone position were *** width of the intertransverse space(D_(P)),the height of the rib neck/head above the lower transverse process(D_(R)),the width of the lateral border of the articular process/lamina(W_(P)),and the width of the posterior border of the vertebral body(W_(V))were *** the upper 1/3 of the intervertebral foramina,the horizontal inclination angle(α)from the lateral border of the articular process/lamina to the posterolateral border of the vertebral body was *** ratios D_(R)/D_(P) and W_(P)/W_(V) were *** intervertebral foramen parameters were compared between *** No rib head/neck occlusion(D_(R)/D_(P)>0)was found in the intertransverse spaces of T1-2 and *** incidence of occlusion for the upper thoracic segments(T1-5,n=138),middle thoracic segments(T5-9,n=116),and lower thoracic segments(T9-L1,n=80)were 76.81%,100%,and 82.50%,*** incidence of occlusion for the middle thoracic segments was significantly higher than that for the upper and lower thoracic segments(P1/2 occlusion(D_(R)/D_(P)>1/2)for the upper,mid

关键词： Thoracic intervertebral foramen Puncture Computed tomography Threedimensional reconstruction Rib

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of proton pump inhibitors on clinical outcomes in patients after acute myocardial infarction: a propensity score analysis from China Acute Myocardial Infarction(CAMI) registry

引用

Journal of Geriatric Cardiology 2020年第11期17卷 659-665页

作者： Wen-Ce SHI Si-De GAO Jin-Gang YANG xiao-xue fan Lin NI Shu-Hong SU Mei YU Hong-Mei YANG Meng-Yue YU Yue-Jin YANG Department of Cardiology State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Research and Biometrics Center State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Xinxiang Central Hospital XinxiangHenan ProvinceChina Langfang People’s Hospital LangfangHebei ProvinceChina First Hospital of Qinhuangdao QinhuangdaoHebei ProvinceChina

Background Proton pump inhibitors(PPIs) are recommended by the latest guidelines to reduce the risk of bleeding in acute myocardial infarction(AMI) patients treated with dual antiplatelet therapy(DAPT). However, previous pharmacodynamic and clinical studies have reported controversial results on the interaction between PPI and the P2 Y12 inhibitor clopidogrel. We investigated the impact of PPIs use on in-hospital outcomes in AMI patients, aiming to provide a new insight on the value of PPIs. Methods A total of 23,380 consecutive AMI patients who received clopidogrel with or without PPIs in the China Acute Myocardial Infarction(CAMI) registry were analyzed. The primary endpoint was major adverse cardiovascular and cerebrovascular events(MACCE) defined as a composite of in-hospital cardiac death, re-infarction and stroke. Propensity score matching(PSM) was used to control potential baseline confounders. Multivariate logistic regression analysis was performed to evaluate the effect of PPIs use on MACCE and gastrointestinal bleeding(GIB). Results Among the whole AMI population, a large majority received DAPT and 67.5% were co-medicated with PPIs. PPIs use was associated with a decreased risk of MACCE(Before PSM OR: 0.857, 95% CI: 0.742-0.990, P = 0.0359;after PSM OR: 0.862, 95% CI: 0.768-0.949, P = 0.0245) after multivariate adjustment. Patients receiving PPIs also had a lower risk of cardiac death but a higher risk of complicating with stroke. When GIB occurred, an alleviating trend of GIB severity was observed in PPIs group. Conclusions Our study is the first nation-wide large-scale study to show evidence on PPIs use in AMI patients treated with DAPT. We found that PPIs in combination with clopidogrel was associated with decreased risk for MACCE in AMI patients, and it might have a trend to mitigate GIB severity. Therefore, PPIs could become an available choice for AMI patients during hospitalization.

关键词： Acute myocardial infarction Clopidogrel Drug interaction Propensity score

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Theoretical Studies of oxetane,azetidine and cyclobutane derivatives

Theoretical Studies of oxetane,azetidine and cyclobutane der...

引用

第九届全国计算（机）化学学术会议

作者： xiao-WEI fan xue-HAI JU (Department of Chemistry,Nanjing University of Science and Technology,Nanjing 210094,

Oxetane,azetidine and cyclobutane derivations are important four-membered ring *** obtain novel high-density and high-energy materials,scientists have managed to attach groups that are essentially needed for the combustion(so-called energetic groups),such as NO,NF,ONO and N groups,to the strained heterocyclic or homocyclic ring to form its derivatives with good explosive *** functional theory(DFT)method has been employed to study the geometric and electronic structures of a scries of four-membered ring compounds at the B3LYP/6-311Gand the B3P86/*** the isedesmic reactions designed for the computation of heats of formation(HOFs),the 3,3-dimethyl-oxetane,azetidine and cyclobutane were chosen as reference *** HOFs for N substituted derivations are larger than that of oxetane compounds with -ONO and/or-NF substituent *** HOFs for oxetane with -ONO and/or -NF substituent groups are negative,while the HOFs for N substituted derivations are *** azetidine compounds,the substituent groups on the azetidine ring affect the HOFs,which increase as the difluoroamino group being replaced by the nitro *** magnitudes of intramolecular group interactions were predicted through the disproportionation *** cyclobutane derivations have the geminal groups,which have larger repulsion *** strain energy(SE)for the title compounds has been calculated using hornodesmotic *** azetidine compounds,the NF group connecting N atom on the ring decrease the SE of title *** stability were evaluated via bond dissociation energies(BDE)at the UB3LYP/*** the oxetane compounds,the O-NO bond is easier to break than that of the C-C bond on the *** the azetidine and cyclobutane compounds,the homolysises of C-NX and/or N-NX(X=O,F)bonds are primal,step for bond *** properties of the title compounds were evaluated by using the Karnlet-Jacobs equation based on the calcul

关键词： oxetane azetidine and cyclobutane derivatives heats of formation density functional theory isodesmic reaction homodesmotic reaction intramolccular group interaction strain energy bond dissociation energy detonation velocity detonation pressure

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

SIRT3在心血管疾病中的作用

引用

生理科学进展 2019年第4期50卷 256-258页

作者：薛晓帆齐丹周立春曲爱娟首都医科大学附属北京朝阳医院西院神经内科北京100043 首都医科大学基础医学院生理学与病理生理学系重塑相关心血管疾病教育部重点实验室代谢紊乱相关心血管疾病北京市重点实验室

沉默信息调节因子2相关酶类3(silent mating type information regulation2 homolog-3,SIRT3)是一种依赖于烟酰胺腺嘌呤二核苷酸(nicotinamide-adenine dinucleotide,NAD)的III类去乙酰化酶。SIRT3主要定位于线粒体,广泛分布于肾脏、脑、心脏及肝脏等富含线粒体的组织器官中,其可对组蛋白和非组蛋白去乙酰化在调控细胞代谢、细胞周期、细胞凋亡及细胞寿命方面起着重要的作用。SIRT3通过去乙酰化相关靶蛋白调节其生物活性,在抵抗氧化应激反应,改善血管内皮细胞功能等多种心血管疾病中,都起到了保护性作用。该文旨在对SIRT3在常见的心血管疾病中的作用的研究进展进行综述。

关键词： Sirtuin 3 线粒体去乙酰化心血管疾病

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

高陡复杂区速度研究及应用

引用

石油地球物理勘探 2004年第3期39卷 300-303页

作者：何诚袁勇游文秀唐晓雪杨帆四川石油管理局地质调查处

本文以准噶尔盆地南缘 GMD地区的资料为例 ,阐述了时深转换速度场的建立过程。首先通过拉格朗日公式对叠加速度进行编辑 (基准面的校正、异常值的剔除、叠加速度的加密内插 ) ,然后将叠加速度进行倾角校正转换成均方根速度 ,再由迪克斯... 详细信息

本文以准噶尔盆地南缘 GMD地区的资料为例 ,阐述了时深转换速度场的建立过程。首先通过拉格朗日公式对叠加速度进行编辑 (基准面的校正、异常值的剔除、叠加速度的加密内插 ) ,然后将叠加速度进行倾角校正转换成均方根速度 ,再由迪克斯公式换算为层速度 ,随后对每条线的层速度剖面进行内插得到速度场 ,最后利用该速度场进行时深转换 ,从而校正了同相轴的畸变 ,得到地下准确的构造形态。通过实际应用表明 ,本文提出的求取速度场方法是合理的。值得提及的是在对速度场平面插值时 ,除用井约束外 ,还必须考虑构造的变化情况 ,才能获得更为准确的速度场。

关键词：准噶尔盆地速度场均方根速度层速度叠加速度时深转换技术地震勘探技术

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias

引用

Neural Regeneration Research 2025年第9期20卷 2585-2586页

作者： Andrew Gregory Chengyun Tang fan fan Department of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global *** the World Health Organization,AD/ADRD has affected more than 55 million individuals worldwide,with an additional 10 million cases diagnosed each year.

关键词： Alzheimer population drug

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tackling the microlensing wave effects of strong lensing gravitational waves with TAAH

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 257-258页

作者： Zuhui fan South-Western Institute for Astronomy Research Yunnan University

The rapid development of gravitational wave（GW） observations since their first detection in 2015 [1] has opened a completely new window for exploring the Universe. Consequently, astronomical research has entered the multimessenger era, allowing us to use different tracers to view the cosmos from various perspectives. Among others, the appealing application of gravitational wave events from compact binary mergers is that they can act as standard sirens to determine absolute cosmic distances entirely independent of standard candles. This approach is one of the most promising means to solve the current H0tension problem.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

伴自身免疫性甲状腺炎的肾上腺皮质激素反应性脑病临床分析

引用

中国现代神经疾病杂志 2013年第6期13卷 538-543页

作者：陈海贾建平许二赫薛晓帆笪宇威首都医科大学宣武医院神经内科北京100053

目的探讨伴自身免疫性甲状腺炎的肾上腺皮质激素反应性脑病的发病形式、临床表现、实验室检查以及影像学特点,以期早期明确诊断和及时治疗。方法回顾分析17例临床诊断明确的伴自身免疫性甲状腺炎的肾上腺皮质激素反应性脑病患者的临床资... 详细信息

目的探讨伴自身免疫性甲状腺炎的肾上腺皮质激素反应性脑病的发病形式、临床表现、实验室检查以及影像学特点,以期早期明确诊断和及时治疗。方法回顾分析17例临床诊断明确的伴自身免疫性甲状腺炎的肾上腺皮质激素反应性脑病患者的临床资料,总结其发病特点、诊断及治疗原则。结果 17例患者分别以癫发作(4例)、精神情绪异常(4例)、记忆力减退(4例)、行走不稳(2例)、头痛(2例)、构音障碍(1例)发病;其中急性发病3例、亚急性发病5例、慢性发病9例。所有患者血清抗甲状腺过氧化物酶抗体水平均升高,15例抗甲状腺球蛋白抗体水平升高;脑脊液蛋白定量轻度升高;脑电图以慢波(5例)或样放电(2例)为主,MRI表现为颅内多发病灶(11例);临床免疫学指标及肿瘤标志物均于正常值范围。甲泼尼龙(11例)或地塞米松(3例)治疗有效且预后良好,仅2例复发。结论伴自身免疫性甲状腺炎的肾上腺皮质激素反应性脑病发病形式多样,以癫发作、认知功能障碍、情绪改变为主要表现,血清抗甲状腺抗体水平升高,MRI可见灰质和白质多发病变。

关键词：甲状腺炎自身免疫性脑疾病自身抗体碘化物过氧化物酶甲状腺球蛋白

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

引用

Science China Chemistry 2025年第1期 174-180页

作者： fan-xiao Meng Xing-Yu Wang Ka Lu Ju-Song Yang Fu-Min Zhang Ai-Jun Ma Bao Du Yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integration of perioperative features and intragraft TCF7L2 expression to predict lipid metabolic disorder in liver transplant recipients

引用

Science China Life Sciences 2025年第1期 297-299页

作者： Junbin Zhou Rongli Wei Guanghan fan Zhengxing Lian Xuanyu Zhang Linsong Tang Zhetuo Qi Haiyang Xie Shusen Zheng Qiang Wei xiao Xu Department of Hepatobiliary and Pancreatic Surgery People's Hospital of LishuiAffiliated Lishui Hospital of Wenzhou Medical UniversityThe First Affiliated Hospital of Lishui University NHFPC Key Laboratory of Combined Multi-Organ Transplantation Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryHangzhou First People's Hospital Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of Medicine Department of Urology The Second Affiliated HospitalZhejiang University School of Medicine Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan (Hangzhou) Hospital Hangzhou Medical College Zhejiang University School of Medicine

Dear Editor, Liver transplantation(LT) is the only curative therapy for patients with endstage liver disease(He et al., 2023; Ling et al., 2022). Post-transplant hypertriglyceridemia(PTHT), which has an incidence of up to 32.8% in 6 months after LT, is one of the major post-transplant complications(Toshima et al., 2020).

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：