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Smart Cellulose‑Based Janus Fabrics with Switchable Liquid Transportation for Personal Moisture and Thermal Management

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Nano-Micro Letters 2025年第1期17卷 333-347页

作者： Jianfeng Xi Yanling lou Liucheng Meng Chao Deng Youlu Chu Zhaoyang Xu Huining xiao Weibing Wu Jiangsu Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsJiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass MaterialsNanjing Forestry UniversityNanjing 210037People’s Republic of China College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada Macromolecular Chemistry and Bavarian Polymer Institute University of BayreuthBayreuth 95440Germany

The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human ***,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a ***,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/*** cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport ***,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability *** fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too *** addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic *** smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.

关键词： Directional water transport Cotton fabric Anti-gravity directional liquid transportation Janus wettability

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Study of the Transport Behavior of Multispherical Proppant in Intersecting Fracture Based on Discrete Element Method

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Energy Engineering 2025年第1期122卷 185-201页

作者： Chengyong Peng JianshuWu Mao Jiang Biao Yin Yishan lou CNOOC Research Institute Company Limited Beijing100028China School of Petroleum Engineering Yangtze UniversityWuhan430100China Hubei Key Laboratory of Oil and Gas Drilling and Production Engineering(Yangtze University) Wuhan430100China

To analyze the differences in the transport and distribution of different types of proppants and to address issues such as the short effective support of proppant and poor placement in hydraulically intersecting fractures,this study considered the combined impact of geological-engineering factors on *** reservoir production parameters and the discrete elementmethod,multispherical proppants were ***,a 3D fracture model,based on the specified conditions of the L block,employed coupled(Computational Fluid Dynamics)CFD-DEM(Discrete ElementMethod)for joint simulations to quantitatively analyze the transport and placement patterns of multispherical proppants in intersecting *** indicate that turbulent kinetic energy is an intrinsic factor affecting proppant ***,the efficiency of placement and migration distance of low-sphericity quartz sand constructed by the DEM in the main fracture are significantly reduced compared to spherical ceramic proppants,with a 27.7%decrease in the volume fraction of the fracture surface,subsequently affecting the placement concentration and damaging fracture *** to small-angle fractures,controlling artificial and natural fractures to expand at angles of 45°to 60°increases the effective support length by approximately 20.6%.During hydraulic fracturing of gas wells,ensuring the fracture support area and post-closure conductivity can be achieved by controlling the sphericity of proppants and adjusting the perforation direction to control the direction of artificial fractures.

关键词： Hydraulic fracturing discrete element method proppant sphericity CFD-DEM

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Prevention and control of coronavirus disease 2019 in Grade-III Class-A hospitals outside of Wuhan

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Chinese Medical Journal 2020年第16期133卷 1978-1980页

作者： Jian-Wen Gu Hong-Jiang Wang Quan-Xing Shi Yang Tao Feng Du Yun-Ming Li Yong-Xing Xu Li-Ping Jia He-Ming Yang xiao-tong lou Ye-Tang xiao Bin Shen Yu-Xia Cheng Yu-Wei Ding Zheng Zhang Xin Guan Shi Wang Li Zhang Yu-Zhong Duan Chuang Nie The Chinese People’s Liberation Army Strategic Support Force Characteristic Medical Center Beijing 100101China General Hospital of Western Theater Command ChengduSichuan 610083China

Now,a novel coronavirus epidemic has posed a major threat to human *** staff face a high risk of occupational exposure at very early stages of an *** the medical staff are infected,it will greatly affect the“fighting capacity”of medical institutions,and help the virus spread within *** issues strongly suggest the critical role of hospital management,prevention,and control systems in the fight against infectious diseases.

关键词： prevention outside fighting

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Multiple dynamic bonds enable high mechanical strength and efficient room-temperature self-healable polyurethane for triboelectric nanogenerators

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Science China Chemistry 2025年

作者： Wenwen Zhang Huixia Xuan xiaofei Xu Jiaming lou Qingbao Guan Zhengwei You State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Institute of Functional Materials College of Materials Science and Engineering Shanghai Key Laboratory of Lightweight Composite Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine Donghua University

For room temperature self-healing triboelectric nanogenerators（TENGs）, the inherent contradiction between mechanical strength and self-healing properties was an urgent problem to be solved. Based on the phenol-carbamate bond, this paper proposed a strategy to design a new molecular structure and coordinate the triple dynamic bonds, which provided a feasible strategy to solve this contradiction. With polytetramethylene ether glycol（M_n= 1,000） as the soft segment in the main chain of polyurethane（PU）, meanwhile methylene diphenyl diisocyanate and 4,4′-dihydroxybiphenyl（BP） as the hard segment and chain extension agent, respectively, the combination of tetrad benzene ring endowed the resultant 4BP-PU with π-π interaction. The effective reversible dissociation and association with hydrogen bond not only bestowed 4BP-PU with high mechanical strength（16.14 MPa）, but also promoted high self-healing efficiency（94.8%） at room temperature. 4BP-PU was selected as the elastic substrate between polydimethylsiloxane and copper sheet to prepare a self-healing TENG to collect energy from natural ***, the rational molecular structure design provided new ideas for developing self-healing materials and fabricating energy harvest electronics.

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Preparation of silver nanoparticles through the reduction of straw-extracted lignin and its antibacterial hydrogel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 504-514页

作者： lou Zhang Shuo Li Fu Tang Jingkai Zhang Yuetong Kang Hean Zhang Lidong Li State Key Laboratory for Advanced Metals and Materials School of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijing 100083China

Silver nanoparticles(Ag NPs)have attracted attention in the field of biomaterials due to their excellent antibacterial ***,the reducing and stabilizing agents used for the chemical reduction of Ag NPs are usually toxic and may cause water *** this work,Ag NPs(31.2 nm in diameter)were prepared using the extract of straw,an agricultural waste,as the reducing and stabilizing *** analysis revealed that the straw extract contained lignin,the structure of which possesses phenolic hydroxyl and methoxy groups that facilitate the reduction of silver salts into Ag *** surfaces of Ag NPs were negatively charged due to the encapsulation of a thin layer of lignin molecules that prevented their *** the prepared Ag NPs were added to the precursor solution of acrylamide,free radical polymerization was triggered without the need for extra heating or light irradiation,resulting in the rapid formation of an Ag NP-polyacrylamide composite *** inhibition zone test proved that the composite hydrogel possessed excellent antibacterial ability due to the presence of Ag *** prepared hydrogel may have potential applications in the fabrication of biomedical materials,such as antibacterial dressings.

关键词： silver nanoparticles hydrogel straw extraction antibacterial

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Role of the globus pallidus in motor and non-motor symptoms of Parkinson's disease

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Neural Regeneration Research 2025年第6期20卷 1628-1643页

作者： Yimiao Jiang Zengxin Qi Huixian Zhu Kangli Shen Ruiqi Liu Chenxin Fang Weiwei lou Yifan Jiang Wangrui Yuan Xin Cao Liang Chen Qianxing Zhuang Department of Physiology School of MedicineNantong UniversityNantongJiangsu ProvinceChina Department of Neurosurgery Huashan HospitalShanghai Medical CollegeFudan UniversityShanghaiChina National Center for Neurological Disorders ShanghaiChina Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration ShanghaiChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institute of Brain ScienceFudan UniversityShanghaiChina

The globus pallidus plays a pivotal role in the basal ganglia circuit. Parkinson's disease is characterized by degeneration of dopamine-producing cells in the substantia nigra, which leads to dopamine deficiency in the brain that subsequently manifests as various motor and non-motor symptoms. This review aims to summarize the involvement of the globus pallidus in both motor and non-motor manifestations of Parkinson's disease. The firing activities of parvalbumin neurons in the medial globus pallidus, including both the firing rate and pattern, exhibit strong correlations with the bradykinesia and rigidity associated with Parkinson's disease. Increased beta oscillations, which are highly correlated with bradykinesia and rigidity, are regulated by the lateral globus pallidus. Furthermore,bradykinesia and rigidity are strongly linked to the loss of dopaminergic projections within the cortical-basal ganglia-thalamocortical loop. Resting tremors are attributed to the transmission of pathological signals from the basal ganglia through the motor cortex to the cerebellum-ventral intermediate nucleus circuit. The cortico–striato–pallidal loop is responsible for mediating pallidi-associated sleep disorders. Medication and deep brain stimulation are the primary therapeutic strategies addressing the globus pallidus in Parkinson's disease. Medication is the primary treatment for motor symptoms in the early stages of Parkinson's disease, while deep brain stimulation has been clinically proven to be effective in alleviating symptoms in patients with advanced Parkinson's disease,particularly for the movement disorders caused by levodopa. Deep brain stimulation targeting the globus pallidus internus can improve motor function in patients with tremordominant and non-tremor-dominant Parkinson's disease, while deep brain stimulation targeting the globus pallidus externus can alter the temporal pattern of neural activity throughout the basal ganglia–thalamus network. Therefore, the comp

关键词： anxiety basal ganglia bradykinesia deep brain stimulation depression globus pallidus externus globus pallidus internus lateral globus pallidus medial globus pallidus neural circuit Parkinson's disease

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Research on Hepatocyte Regulation of PCSK9-LDLR and Its Related Drug Targets

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Chinese Journal of Integrative Medicine 2024年第7期30卷 664-672页

作者： LIU Su-su YU tong QIAO Yan-fang GU Shu-xiao CHAI Xin-lou School of Traditional Chinese Medicine Beijing University of Traditional Chinese MedicineBeijing102401China

The prevalence of hyperlipidemia has increased significantly due to genetic, dietary, nutritional and pharmacological factors, and has become one of the most common pathological conditions in humans. Hyperlipidemia can lead to a range of diseases such as atherosclerosis, stroke, coronary heart disease, myocardial infarction, diabetes, and kidney failure, etc. High circulating low-density lipoprotein cholesterol (LDL-C) is one of the causes of hyperlipidemia. LDL-C in the blood binds to LDL receptor (LDLR) and regulates cholesterol homeostasis through endocytosis. In contrast, proprotein convertase subtilisin/kexin type 9 (PCSK9) mediates LDLR degradation via the intracellular and extracellular pathways, leading to hyperlipidemia. Targeting PCSK9-synthesizing transcription factors and downstream molecules are important for development of new lipid-lowering drugs. Clinical trials regarding PCSK9 inhibitors have demonstrated a reduction in atherosclerotic cardiovascular disease events. The purpose of this review was to explore the target and mechanism of intracellular and extracellular pathways in degradation of LDLR and related drugs by PCSK9 in order to open up a new pathway for the development of new lipid-lowering drugs.

关键词： hyperlipidemia proprotein convertase subtilisin/kexin type 9 low-density lipoprotein receptor intracellular pathway extracellular pathway

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Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer's disease

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Acta Pharmaceutica Sinica B 2015年第1期5卷 25-33页

作者： Hongjuan tong Kaiyan lou Wei Wang Shanghai Key Laboratory of Chemical Biology School of Pharmacy State Key Laboratory of Bioengineering ReactorEast China University of Science and Technology Department of Chemistry and Chemical Biology University of New Mexico

One of the early pathological hallmarks of Alzheimer's disease(AD) is the deposition of amyloid-β(Aβ) plaques in the brain. There has been a tremendous interest in the development of Aβ plaques imaging probes for early diagnosis of AD in the past decades. Optical imaging, particularly near-infrared fluorescence(NIRF) imaging, has emerged as a safe, low cost, real-time, and widely available technique, providing an attractive approach for in vivo detection of Aβ plaques among many different imaging techniques. In this review,we provide a brief overview of the state-of-the-art development of NIRF Aβ probes and their in vitro and in vivo applications with special focus on design strategies and optical, binding, and brain-kinetic properties.

关键词： Alzheimer’s disease Blood-brain barrier Fluorescence probe Near-infrared fluorescence Optical imaging Amyloid-β plagues

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Mechanical Properties Study of Reinforced Thermoplastic Pipes Under A Tensile Load

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China Ocean Engineering 2020年第6期34卷 806-816页

作者： WANG Yang-yang lou Min tong Bing WANG Sen School of Petroleum Engineering China University of Petroleum(East China)Qingdao 266580China Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao 266580China Hoisting Machinery Business Division Xuzhou Construction Machinery Group(XCMG)Xuzhou 221000China Weihai Nacheon Pipeline Co. Ltd.Weihai 264400China

This paper presents a study on the tensile properties of reinforced thermoplastic pipes(RTPs). A mechanical model of RTPs with an arbitrary number of reinforced layers under tensile action is constructed by combining the constitutive relationship of elastoplastic materials with the continuous displacement condition. On this basis, the effects of various parameters such as the winding angle, the number of structurally reinforced layers, and the inner polyethylene(PE) liner thickness on the tensile properties of the RTPs were analyzed, and a tensile test was carried out for validation. The results showed that the winding angle of the structurally reinforced layers was the main factor affecting an RTP's tensile performance— decreases in the winding angle significantly improved its tensile ability,especially the longitudinal strength. With ±45° as the demarcation point, the winding angle smaller than ±45° will result in higher strength in longitudinal direction, and the lifting effect on RTP's mechanical properties of the increasing number of reinforcement layers was better than that of the increasing thickness of the lining layer;when the winding angle was larger than ±45°, the opposite results were obtained. The fibre load was more sensitive to the winding angle than the PE load.

关键词： reinforced thermoplastic pipes tensile properties winding angle polyethylene

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A system dynamics urban water management model for Macao, China

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Journal of Environmental Sciences 2016年第12期28卷 117-126页

作者： tong Wei Inchio lou Zhifeng Yang Yingxia Li State Key Laboratory of Water Environment Simulation School of Environment Beijing Normal University Beijing 100875 China. Department of Civil and Environmental Engineering University of Macao Macao 999078 China

Urban water resources have been facing significant pressure from population growth, urbanization, and climate change. A system dynamics urban water management model was proposed to simulate the dynamic interactions between urban water demands and society, economy, climate, and water conservation. The residents＇ water conseration willingness was incorporated in the model and water-saving effects were quantified. The simulation results for Macao showed that population size was the main driving force for urban water demand. The change of temperature and precipitation has obvious effects on the landscape water demand. The water demand output is sensitive to the change in population, per capita demand, and temperature. Increased precipitation will reduce urban water demand and increased economic growth will increase water demand. By implementing integrated water conservation measures and imoroved water conservation willinmaess, water demand could be reduced bv 17.5%.

关键词： Macao System dynamics Water conservation willingness Water demand

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