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Cretaceous crown male ant reveals the rise of modern lineages

Zoological Research 2024年第5期45卷 983-989页

作者： Qiong Wu Alexander g.Radchenko Michael S.Engel xiao-Qin Li Hong-Ru Yang Xing-Ru Li Chung-Kun Shih Dong Ren Tai-Ping gao College of Life Sciences Capital Normal UniversityBeijing 100048China I.I.Schmalhausen Institute of Zoology NAS of UkraineKiev 01054Ukraine Division of Invertebrate Zoology American Museum of Natural HistoryNew York 10024-5192USA Facultad de Ciencias Biológicas Universidad Nacional Mayor de San MarcosLima 11-0058Perú Departamento de Entomología Museo de Historia NaturalUniversidad Nacional Mayor de San MarcosLima 15072Perú Department of chemistry Analytical and Testing CenterCapital Normal UniversityBeijing 100048China Department of Paleobiology National Museum of Natural HistorySmithsonian InstitutionWashington DC 20013-7012USA

Most described Mesozoic ants belong to stem groups that existed only during the Cretaceous ***,the earliest known crown ants were dated to the Turonian(Late Cretaceous,ca.94-90 million years ago(Ma))deposits found in the USA,Kazakhstan,and ***,the recent discovery of an alate male ant in Kachin amber from the earliest Cenomanian(ca.99 Ma),representing a new genus and species,Antiquiformica alata,revises the narrative on ant *** can be distinctly differentiated from all known male stem ants by its geniculate antennae with elongated scape,extending far beyond the occipital margin of the head and half the length of the funiculus,as well as its partly reduced forewing ***,the combination of a one-segmented waist with a well-developed node,elongated scape extending beyond the occipital margin,and reduced forewing venation,particularly the completely reduced m-cu and rs-m crossveins and absence of rm and mcu closed cells,firmly places the fossil within the extant subfamily *** transform infrared spectroscopy(FTIR)confirmed that the amber containing Antiquiformica alata originated from the Kachin mines in *** discovery significantly revises our understanding of the early evolution of *** presence of Antiquiformica in Cenomanian amber indicates that the subfamily Formicinae emerged at least by the start of the Late Cretaceous,with crown ants likely originating earlier during the earliest Cretaceous or possibly the Late Jurassic,although paleontological evidence is lacking to support the latter hypothesis.

关键词： Formicidae Formicinae Morphology Taxonomy Antiquiformica alata Paleontology Kachin amber

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瑞典体医融合服务模式经验及启示

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体育文化导刊 2024年第1期 48-55页

作者：刘晓旭车磊山西师范大学体育学院太原030031 北京大学体育教研部北京100080

运用文献资料,逻辑分析等方法,阐述瑞典体医融合服务模式概况、经验,并提出对我国的启示。从形成动因、指导思想、流程内容三方面阐述了瑞典体医融合服务模式概况。经验:国家战略推动,提供方向指导;多方共同参与,倡导资源整合;基于循证... 详细信息

运用文献资料,逻辑分析等方法,阐述瑞典体医融合服务模式概况、经验,并提出对我国的启示。从形成动因、指导思想、流程内容三方面阐述了瑞典体医融合服务模式概况。经验:国家战略推动,提供方向指导;多方共同参与,倡导资源整合;基于循证实践,提供循证建议;以个人为中心,重视社区基础。启示:强化支撑体系,健全制度保障;强调循证依据,落实运动处方;夯实社区基础,提升健康服务;强调随访追踪,完善持续监督。

关键词：群众体育体医融合体力活动初级保健瑞典

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Self‑Assembly MXene‑rgO/CoNi Film with Massive Continuous Heterointerfaces and Enhanced Magnetic Coupling for Superior Microwave Absorber

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Nano-Micro Letters 2022年第5期14卷 20-33页

作者： xiao Li Zhengchen Wu Wenbin You Liting Yang Renchao che Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsFudan UniversityShanghai 200438People’s Republic of China Department of Materials Science Fudan UniversityShanghai 200438People’s Republic of China

MXene, as a rising star of two-dimensional(2 D) materials, has been widely applied in fields of microwave absorption and electromagnetic shielding to cope with the arrival of the 5 g era. However, challenges arise due to the excessively high permittivity and the difficulty of surface modification of few-layered MXenes severely, which infect the microwave absorption performance. Herein, for the first time, a carefully designed and optimized electrostatic selfassembly strategy to fabricate magnetized MXene-r gO/Co Ni film was reported. Inside the synthesized composite film, r gO nanosheets decorated with highly dispersed Co Ni nanoparticles are interclacted into MXene layers, which effectively suppresses the originally self-restacked of MXene nanosheets, resulting in a reduction of high permittivity. In addition, owing to the strong magnetic coupling between the magnetic Fe Co alloy nanoparticles on the r gO substrate, the entire MXener gO/Co Ni film exhibits a strong magnetic loss capability. Moreover, the local dielectric polarized fields exist at the continuous heterointerfaces between 2 D MXene and r gO further improve the capacity of microwave loss. Hence, the synthesized composite film exhibits excellent microwave absorption property with a maximum reflection loss value of-54.1 d B at 13.28 gHz. The electromagnetic synergy strategy is expected to guide future exploration of high-efficiency MXene-based microwave absorption materials.

关键词： MXene Microwave absorption Composite materials graphene Electron holography

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Synthesis and Crystal Structure of a Novel Three-dimensional Complex Ni(Iz)_2(Bdc)(H_2O)_2 (Iz = Imidazole,Bdc = 1,4-Benzenedicarboxylate)

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Chinese Journal of Structural chemistry 2006年第7期25卷 818-822页

作者： TAN xiao-Na che Yun-Xia ZHENg Ji-Min Department of chemistry Nankai University Tianjin 300071 China

A novel nickel（Ⅱ） complex Ni（Iz）2（Bdc）（H2O）2 （Iz = imidazole, Bdc = 1,4-benzenedicarboxylate） has been synthesized and structurally characterized by X-ray analysis. The crystal is of monoclinic, space group P2 1/n with a = 5.5079（5）, b = 15.0973, c = 9.9825（9） A, β = 90.2380（10）°, C14H16N4NiO6, Mr = 395.02, Z = 2, V = 830.08（13） A^3 Dc = 1.580 g/cm^3, μ（MoKa） = 1.208 mm^-1, F（000） = 408, R = 0.0234 and wR = 0.0603 for 1379 observed reflections （I 〉 2σ（I））. In the title complex, adjacent nickel（Ⅱ） ions are bridged through the oxygen atoms of carboxylic groups in syn-anti conformation, yielding an infinite one-dimensional chain. These chains are linked to each other to form a 3-D network structure by three kinds of hydrogen-bonding interactions.

关键词： synthesis crystal structure nickel(Ⅱ) complex 1,4-benzenedicarboxylate

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富硒对纳豆菌发酵鹰嘴豆产血管紧张素转化酶抑制肽的影响

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食品研究与开发 2024年第13期45卷 39-47页

作者：徐颖车佳瑞王洋肖斌陕西科技大学食品科学与工程学院陕西西安710021

该研究将富硒能力较强的纳豆芽孢杆菌作为发酵菌种,鹰嘴豆为原料,以血管紧张素转化酶(angiotensin I converting enzyme,ACE)抑制率为指标,采用单因素试验和响应面优化法对纳豆芽孢杆菌富硒后产ACE抑制肽的最佳条件进行优化。同时采用... 详细信息

该研究将富硒能力较强的纳豆芽孢杆菌作为发酵菌种,鹰嘴豆为原料,以血管紧张素转化酶(angiotensin I converting enzyme,ACE)抑制率为指标,采用单因素试验和响应面优化法对纳豆芽孢杆菌富硒后产ACE抑制肽的最佳条件进行优化。同时采用超高效液相色谱-电喷雾电离-串联质谱(ultra performance liquid chromatography electrospray ionization tandem mass spectrometry,UPLC-ESI-MS/MS)法对鹰嘴豆纳豆富硒后硒代氨基酸进行定性定量分析。结果表明,L-硒代胱氨酸是鹰嘴豆纳豆富硒后主要的硒代氨基酸,纳豆芽孢杆菌富硒后产ACE抑制肽的最佳条件为接种量2%、液料比18∶1(mL/g)、发酵温度40℃,ACE抑制率可达89.24%。对比试验的结果显示,纳豆芽孢杆菌不富硒发酵鹰嘴豆产ACE抑制肽活性为66.35%,表明富硒纳豆芽孢杆菌发酵鹰嘴豆对ACE活性有良好的抑制作用。

关键词：富硒鹰嘴豆血管紧张素转化酶抑制率降血压活性硒代氨基酸

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兔豆状囊尾蚴Ⅰ型胱抑素对脂多糖诱导小鼠脓毒症防治机制的研究

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中国预防兽医学报 2024年第8期46卷 837-846页

作者：车亮王由森石正发李甲羊倩倩肖琴孙晓林甘肃农业大学动物医学院寄生虫实验室甘肃兰州730070 中牧实业股份有限公司兰州生物药厂甘肃兰州730070

为深入探究兔豆状囊尾蚴半胱氨酸蛋白酶抑制剂(CPI)超家族成员I型胱抑素(Stefin)对脂多糖(LPS)诱导的小鼠脓毒症的治疗效果,本研究将重组菌pgEX-4T-CpStefin/BL21经IPTg诱导表达重组Stefin蛋白(r-Stefin),采用gST试剂盒纯化上述蛋白,并... 详细信息

为深入探究兔豆状囊尾蚴半胱氨酸蛋白酶抑制剂(CPI)超家族成员I型胱抑素(Stefin)对脂多糖(LPS)诱导的小鼠脓毒症的治疗效果,本研究将重组菌pgEX-4T-CpStefin/BL21经IPTg诱导表达重组Stefin蛋白(r-Stefin),采用gST试剂盒纯化上述蛋白,并去除内毒素后,采用SDS-PAgE检测r-Stefin的纯化效果。结果显示,r-Stefin在大肠杆菌中获得了表达且纯化效果较好。将雄性BALB/c小鼠随机分为6组,每组16只,分别为A组(生理盐水100μL/只,阴性对照组)、B组:gST蛋白对照组(25μg/只)、C组:r-Stefin组(25μg/只)、D组:脓毒症组(0.2 mg/100μL LPS/只)、E组:gST蛋白干预组(0.2 mg/100μL/只LPS+gST蛋白25μg/只)、F组:r-Stefin干预组(0.2 mg/100μL LPS/只+r-Stefin 25μg/只)。经腹腔注射后观察各组小鼠的临床症状、绘制各组小鼠在LPS诱导后不同时间的生存率曲线。在LPS诱导后12 h和24 h对各组小鼠采血,采用ELISA检测各组小鼠血清中各炎性细胞因子的含量,通过全自动生化仪测定各组小鼠血清中肝、肾功能指标。结果显示,D、E组小鼠经LPS诱导后很快出现被毛发凌乱、活动量减少、精神沉郁等症状。F组小鼠上述症状在一定程度上得到改善。A、B、C组小鼠均健活。生存率曲线显示,D组小鼠在36 h内全部死亡,E组小鼠在48 h~60 h时的生存率由75%快速降至72 h时的37.5%,F组小鼠的生存率在72 h时达75%。A~C组小鼠生存率均达100%。ELISA结果显示,LPS诱导12 h时,D组、E组和F组小鼠血清中促炎细胞因子(IL-6、TNF-α和TNF-β)及抑炎细胞因子(IL-10)的含量与A组相比均极显著升高;D组小鼠血清中IL-10含量显著低于F组。TNF-α及TNF-β含量分别极显著和显著高于F组。LPS诱导24 h时,D组小鼠血清中IL-6、TNF-α和TNF-β含量极显著高于F组,IL-10含量极显著低于F组。经LPS诱导后12 h,D组、E组、F组小鼠血清中肝脏指标ALB的含量与A组相比均极显著下降(P<0.001),ALT含量均极显著升高。D组小鼠血清中ALB和ALT含量显著或极显著高于F组;LPS诱导24 h时,D组小鼠血清中ALB的含量极显著低于F组,ALT的含量极显著高于F组。LPS诱导12 h时,D组、E组、F组小鼠血清中肾脏指标BUN和CREA的含量与A组相比均极显著升高,D组小鼠血清中BUN和CREA的含量均显著高于F组。LPS诱导24 h时,D组小鼠血清中BUN和CREA的含量均极显著高于F组。病变观察结果显示,LPS诱导后12 h,各组小鼠各脏器组织病变均无差别;LPS诱导后24 h,D组和E组小鼠肺、肝、肾组织均出现较严重的病理改变,而F组小鼠上述各组织病变均得到了改善。A、B、C组小鼠各组织均无明显病变。上述结果表明,r-Stefin干预可减轻脓毒症小鼠的炎症反应,使其肝肾功能明显好转,各组织病变明显减轻。综上所述,本研究首次证实Stefin蛋白对LPS诱导的小鼠脓毒症有明显的治疗作用,具有成为治疗脓毒症候选药物的潜力,为深入探究脓毒症的发病机制及开发新的治疗药物提供实验依据。

关键词：半胱氨酸蛋白酶抑制剂小鼠脓毒症脂多糖

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滋阴凉血方联合泼尼松对免疫性血小板减少性紫癜小鼠免疫功能及ST2/IL-33通路的影响

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中国实验血液学杂志 2024年第1期32卷 202-207页

作者：赵冰洁车虹胡琏易文静肖利刘培佳刘松山成都中医药大学附属医院血液科四川成都610072

目的:探讨滋阴凉血方联合泼尼松对免疫性血小板减少性紫癜小鼠免疫功能及ST2/IL-33通路的影响。方法:40只BALB/c小鼠,其中32只采用注射抗血小板血清构建免疫性血小板减少性紫癜小鼠模型,造模成功后,随机分为模型、滋阴凉血方(0.2 ml/10... 详细信息

目的:探讨滋阴凉血方联合泼尼松对免疫性血小板减少性紫癜小鼠免疫功能及ST2/IL-33通路的影响。方法:40只BALB/c小鼠,其中32只采用注射抗血小板血清构建免疫性血小板减少性紫癜小鼠模型,造模成功后,随机分为模型、滋阴凉血方(0.2 ml/10 g)、泼尼松(0.2 ml/10 g)和滋阴凉血方+泼尼松(0.2 ml/10 g)共4组,每组8只,剩余8只小鼠设为空白组。分别按剂量灌胃给药,模型组与空白组灌胃等量生理盐水,1次/d×2周。采集血样和脾脏组织,使用全自动血液分析仪测定外周血小板数;HE染色观察脾脏组织病理学变化;酶联免疫吸附法检测血清转化生长因子β、白细胞介素(IL)-17及外周血血小板生成素水平;Western blot检测脾脏组织IL-33、s ST2、ST2表达;流式细胞术检测外周血Th17、Treg细胞数。结果:与空白组相比,模型组小鼠血小板数、血小板生成素、转化生长因子β水平及Treg细胞均明显降低(Pg细胞均明显上升(Pg平衡,进而有效改善免疫性血小板减少性紫癜,其机制可能与调节ST2/IL-33信号通路有关。

关键词：免疫性血小板减少性紫癜滋阴凉血方泼尼松免疫功能 ST2/IL-33通路

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EDA: an enhanced dual-active algorithm for location privacy preservation in mobile P2P networks

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Journal of Zhejiang University-Science C(Computers and Electronics) 2013年第5期14卷 356-373页

作者： Yan-zhe che Kevin CHIEW xiao-yan HONg Qiang YANg Qin-ming HE College of Computer Science and Technology Zhejiang University School of Engineering Tan Tao University Department of Computer Science University of Alabama College of Electrical Engineering Zhejiang University

Various solutions have been proposed to enable mobile users to access location-based services while preserving their location privacy. Some of these solutions are based on a centralized architecture with the participation of a trustworthy third party, whereas some other approaches are based on a mobile peer-to-peer (P2P) architecture. The former approaches suffer from the scalability problem when networks grow large, while the latter have to endure either low anonymization success rates or high communication overheads. To address these issues, this paper deals with an enhanced dual-active spatial cloaking algorithm (EDA) for preserving location privacy in mobile P2P networks. The proposed EDA allows mobile users to collect and actively disseminate their location information to other users. Moreover, to deal with the challenging characteristics of mobile P2P networks, e.g., constrained network resources and user mobility, EDA enables users (1) to perform a negotiation process to minimize the number of duplicate locations to be shared so as to significantly reduce the communication overhead among users, (2) to predict user locations based on the latest available information so as to eliminate the inaccuracy problem introduced by using some out-of-date locations, and (3) to use a latest-record-highest-priority (LRHP) strategy to reduce the probability of broadcasting fewer useful locations. Extensive simulations are conducted for a range of P2P network scenarios to evaluate the performance of EDA in comparison with the existing solutions. Experimental results demonstrate that the proposed EDA can improve the performance in terms of anonymity and service time with minimized communication overhead.

关键词： Location-based service Privacy preservation Spatial cloaking Mobile peer-to-peer networks

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血清CTRP3、BMP-7及petCO_(2)对呼吸窘迫综合征患儿机械通气撤机的预测价值

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医学检验与临床 2024年第8期35卷 10-14,38页

作者：王楠车晓晴王浩然刘卫平漯河市中心医院儿一科河南漯河462000

目的:探讨新生儿呼吸窘迫综合征(NRDS)血清补体C1q-肿瘤坏死因子相关蛋白3(CTRP3)、骨形态发生蛋白-7(BMP-7)及呼吸末二氧化碳分压(petCO_(2))对机械通气撤机的预测价值。方法:选取80例NRDS患儿为研究对象,依据撤机结局分为成功组54例... 详细信息

目的:探讨新生儿呼吸窘迫综合征(NRDS)血清补体C1q-肿瘤坏死因子相关蛋白3(CTRP3)、骨形态发生蛋白-7(BMP-7)及呼吸末二氧化碳分压(petCO_(2))对机械通气撤机的预测价值。方法:选取80例NRDS患儿为研究对象,依据撤机结局分为成功组54例、失败组26例。比较2组基线资料。分析不同组、不同严重程度患儿petCO_(2)、血清CTRP3、BMP-7水平,分析其与生化指标、疾病严重程度相关性。评价petCO_(2)、血清CTRP3、BMP-7对撤机结局的预测价值。采用SPSS24.0对数据进行分析,计数资料采用×^(2)检验,计量资料采用t检验。结果:治疗12h、24h后成功组petCO_(2)分别为(36.32±1.88)(mmHg)4、(33.06±1.79)(mmHg)4,血清BMP-7水平分别为(44.03±5.17)pg/mL、(41.16±4.88)pg/mL,血清℃TRP3水平分别为(345.59±60.03)μg/L、(377.41±75.80)μg/L;治疗12h、24h后失败组petCO_(2),分别为(38.62±1.93)(mmHg)4、(38.57±1.90)(mmHg)4,血清BMP-7水平分别为(48.82±5.96)pg/mL、(48.39±5.63)pg/mL,血清CTRP3水平分别为(316.68±55.56)μg/L、(320.03±66.67)μg/L,治疗12h、24h后成功组petCO_(2)、血清BMP-7水平低于失败组,血清CTRP3水平高于失败组(PpetCO_(2)、BMP-7与PaO,呈负相关,且与PaCO_(2)、SNAPpe-ⅡI评分、TgF-β1、IL-6、TNF-α、病情严重程度呈正相关,而CTRP3与之相反(PpetCO_(2),联合预测撤机结局的AUC大于单项预测(PpetCO_(2),对NRDS患儿撤机结局预测具有应用价值。

关键词：新生儿呼吸窘迫综合征补体C1q-肿瘤坏死因子相关蛋白3 骨形态发生蛋白-7 呼吸末二氧化碳分压

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genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

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Zoological Research 2024年第4期45卷 833-844页

作者： Ying Liu Lin Yang Hong-Yong Xiang Ming Niu Jia-che.g Deng Xue-Yuan Li Wen-Jie Hao Hong-Sheng Ou-Yang Tong-Yu Liu xiao-Chun Tang Da-Xin Pang Hong-Ming Yuan State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Animal Genome Editing Technology Innovation CenterCollege of Animal SciencesJilin UniversityChangchunJilin 130062China Chifeng Best genetics Technology Co. Ltd.ChifengNei Mongol 024000China Chongqing Jitang Biotechnology Research Institute Co. Ltd.Chongqing 400015China

Porcine reproductive and respiratory syndrome(PRRS)is a globally prevalent contagious disease caused by the positive-strand RNA PRRS virus(PRRSV),resulting in substantial economic losses in the swine *** the CD163 SRCR5 domain,either through deletion or substitution,can eff1ectively confer resistance to PRRSV infection in ***,large fragment modifications in pigs inevitably raise concerns about potential adverse effects on growth *** the impact of genetic modifications on normal physiological functions is a promising direction for developing PRRSV-resistant *** the current study,we identified a specific functional amino acid in CD163 that influences PRRSV *** infection experiments conducted on Marc145 and PK-15CD163 cells illustrated that the mE535g or corresponding pe529g mutations markedly inhibited highly pathogenic PRRSV(HP-PRRSV)proliferation by preventing viral binding and ***,individual viral challenge tests revealed that pigs with the E529g mutation had viral loads two orders of magnitude lower than wild-type(WT)pigs,confirming effective resistance to *** of the physiological indicators and scavenger function of CD163 verified no significant differences between the WT and E529g *** findings suggest that E529g pigs can be used for breeding PRRSV-resistant pigs,providing novel insights into controlling future PRRSV outbreaks.

关键词： PRRSV CD163 Point mutation E529g Pigs

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