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Chinese Chemical Letters 2014年第6期25卷 962-966页

作者： Feng-Jiao Chen Chang-Wang Shao Min-nan Zhao Zhao-Sheng Bu Yan Zhang xiao-nan dai Guo-Wei Zhou Key Laboratory of Fine Chemicals in Universities of Shandong School of Chemistry and Pharmaceutical EngineeringQilu University of Technology School of Chemical Engineering and Environment Weifang University of Science and Technology

Rod-shaped mesoporous titanosilicate composites （RMTSs） with controllable aspect ratios （ARs） were fabricated using cetyltrimethylammonium bromide （CTAB） and ammonium hydroxide （NH4OH） at a continuous stirring rate, resulting in ARs ranging from 1 to 5. Slowing the stirring rate or increasing the concentration of CTAB mainly impacted the length growth, whereas NH4OH affected the width growth. Photocatalytic activity studies revealed that the length of RMTSs played a more significant role than the width at lower ARs in their photocatalytic activity.

关键词： Titanosilicate Aspect ratio Growth direction Photocatalytic activity

Expression of the SET protein in testes of mice at different developmental stages

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Asian Journal of Andrology 2014年第5期16卷 689-693,I0006,I0007页

作者： xiao-nan dai Shan Liu Li Shao Chao Gao Li Gao Jia-Yin Liu Yu-Gui Cui State Key Laboratory of Reproductive Medicine Clinical Center of Reproductive Medicine First Affiliated Hospital Nanjing Medical University Nanjing China

SET is a multifunctional protein involved in regulating many biological processes of the cell cycle. It is also a regulator of steroidogenesis in the ovary. However, the expression of SET protein in testis, and its function, still remains ambiguous. In this study, we observed the expression of SET in the testes of mice at different developmental stages, and have discussed its potential function in regulating spermatogenesis and androgen production. Forty-eight male mice at different developmental stages （1 week old as the infancy group; 4 weeks old as the prepubertal group; 12 weeks old as the adult group; over 12 months old as the ageing group） were used. Cellular location of SET protein in the testes was observed by immuno-histochemistry. Expression levels of Set mRNA and SET protein were analyzed by quantitative polymerase chain reaction and Western blotting. SET protein was expressed in spermatogonial cells and spermatocytes; the highest level was mainly in haploid and tetraploid cells of the prepubertal and adult groups, and Leydig cells of the adult and ageing groups. There was a low expression in Sertoli cells. Expression of Set mRNA in the prepubertal group was significantly higher than that in the adult group （P 〈 0.05）, while expression of SET protein was at the highest level in the adult group （P 〈 0.05）. SET protein is mainly expressed in spermatogonial cells and spermatocytes, and poorly expressed in Sertoli cells, suggesting that it is involved in spermatogenesis. Expression of SET protein in Leydig cells suggests a possible role in steroidogenesis.

关键词： androgen production Leydig cell Sertoli cell SET spermatogenesis

负载重组人骨形态发生蛋白2的纳米羟基磷灰石/丝素蛋白复合材料重建脊柱稳定性

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中国组织工程研究 2017年第18期21卷 2802-2807页

作者：陈晓敏马霄邵南齐代永霞高青付金芳郑州澍青医学高等专科学校河南省郑州市450064

背景:随着骨修复支架在医学领域的广泛应用,具有良好生物学性能的纳米羟基磷灰石和丝素蛋白成为近年来的研究热点。目的:探讨负载重组人骨形态发生蛋白2的纳米羟基磷灰石/丝素蛋白复合材料重建兔脊柱节段初始稳定性的可行性。方法:将36... 详细信息

背景:随着骨修复支架在医学领域的广泛应用,具有良好生物学性能的纳米羟基磷灰石和丝素蛋白成为近年来的研究热点。目的:探讨负载重组人骨形态发生蛋白2的纳米羟基磷灰石/丝素蛋白复合材料重建兔脊柱节段初始稳定性的可行性。方法:将36只雄性新西兰兔随机分为3组,均制备脊柱失稳模型。自体骨组在L4、L5椎间植入自体髂骨,n HA/SF组将纳米羟基磷灰石/丝素蛋白复合材料植入椎间隙进行椎间融合,rhB MP-2/nH A/SF组将负载重组人骨形态发生蛋白2的纳米羟基磷灰石/丝素蛋白复合材料植入椎间隙进行椎间融合。术后12周,X射线观察手术节段的融合情况,然后处死实验动物进行大体观察。使用电子拉力机测试融合节段的稳定性。组织学观察手术部位的植骨融合情况。结果与结论:(1)术后各组标本融合部位质地均较硬。自体骨组融合迹象明显,rhB MP-2/nH A/SF组次之,n HA/SF组未见融合迹象;(2)自体骨组椎体与髂骨植骨块分界处有大量骨小梁长入,nH A/SF组分界处有少量骨小梁长入,rh BMP-2/nH A/SF组分界处骨小梁较多。经X射线评估分别有10只、3只和9只符合融合标准;(3)rh BMP-2/n HA/SF组脊柱活动度与自体骨组间比较差异无显著性意义,rh BMP-2/nH A/SF组脊柱活动度优于nH A/SF组,差异有显著性意义(P<0.05);(4)自体骨组髂骨周边可见骨性连接,n HA/SF组材料周边可见骨性连接,未见成熟骨组织,rh BMP-2/nH A/SF组周边有大量新生毛细血管,并渗入组织内部;(5)结果表明,负载重组人骨形态发生蛋白2的纳米羟基磷灰石/丝素蛋白复合材料具有良好的生物相容性、力学性能和骨诱导能力,能在较短时间内重建兔脊柱稳定性。

关键词：生物材料骨组织工程重组人骨形态发生蛋白2 支架材料纳米羟基磷灰石丝素蛋白脊柱融合兔生物相容性

The Effect of Electrolyte and Polymer on the Thixotropy of Mg-Al-Layered Double Hydroxides/Kaolinite Dispersions

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The Effect of Electrolyte and Polymer on the Thixotropy of M...

Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

中国化学会第十二届胶体与界面化学会议

作者： xiao-nan dai~1,Wan-Guo Hou~2,Hong-Dong Duan~1 1 Department of Chemical Engineering,Shandong Institute of Light Industry,Jinan,250353 2 Key Laboratory for Colloid and Interface Chemistry of Education Ministry,Shandong University,Jinan,250100

Rheological properties of dispersions are important in various industrial processes,such as paper,paint, cement,ceramics and pharmaceuticals,*** thixotropy is one of the most important rheological phenomena of *** this paper,the thixotropy of Mg-Al-layered double hydroxide (LDHs)/kaolinite dispersions has been investigated as a function of concentration of electrolytes(NaCl and CaCl) and polymers(CPAM and HPAM).It was observed that the thixotropy type of LDH/kaolinite

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao Peng Yuefeng Song Ihar Razanau Juanxiu xiao Wei xiao Di Hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Methane Electrochemical conversion Reaction mechanism Catalyst design Electrode Electrocatalysis

Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

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Science China Chemistry 2025年第1期 273-287页

作者： Shuguang Yang Lijun Hu Hong xiao Zecong xiao Xintao Shuai PCFM Lab of Ministry of Education School of Materials Science and Engineering Sun Yat-sen University Department of Ultrasound The Fifth Affiliated Hospital Sun Yat-sen University Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen University nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen University

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy. Nonetheless, the optimization of the catalytic efficiency is often impeded by the inefficient expression of enzymes. Herein, we reported a self-amplifying fluorescent molecular probe, Bis-HTPICG, for photodynamic therapy(PDT) and subsequent PDT-induced immunoreaction. The Bis-HTP-ICG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO), a crucial enzyme secreted by neutrophils at inflammation sites. Upon exposure to laser irradiation, Bis-HTP-ICG showed a high PDT efficacy, inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO secretion. The heightened level of MPO enhances the accumulation of the Bis-HTP-ICG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis, instigating a self-amplifying chain reaction cycle involving Bis-HTP-ICG, neutrophils and ***, PDT efficiently incites immunogenic cell death(ICD) in tumor cells, initiating an anti-tumor immune response including dendritic cells(DCs) maturation, T cell proliferation and reprogramming of tumor-associated neutrophils(TANs). This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

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Research status and prospects of the fractal analysis of metal material surfaces and interfaces

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 20-38页

作者： Qinjin dai Xuefeng Liu Xin Ma Shaojie Tian Qinghe Cui Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Beijing Laboratory of Metallic Materials and Processing for Modern Transportation University of Science and Technology BeijingBeijing 100083China Laboratory for Advanced Materials Processing of Ministry of Education University of Science and Technology BeijingBeijing 100083China School of Mechanical and Electrical Engineering Xinjiang Institute of EngineeringUrumqi 830023China

As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine *** analysis has been used to characterize the shapes of metal materials at various scales and *** methods make it difficult to quantitatively describe the relationship between the regular characteristics and properties of metal material surfaces and ***,fractal analysis can be used to quantitatively describe the shape characteristics of metal materials and to establish the quantitative relationships between the shape characteristics and various properties of metal *** the perspective of two-dimensional planes and three-dimensional curved surfaces,this paper reviews the current research status of the fractal analysis of metal precipitate interfaces,metal grain boundary interfaces,metal-deposited film surfaces,metal fracture surfaces,metal machined surfaces,and metal wear *** relationship between the fractal dimensions and properties of metal material surfaces and interfaces is *** from three perspectives of fractal analysis,namely,research scope,image acquisition methods,and calculation methods,this paper identifies the direction of research on fractal analysis of metal material surfaces and interfaces that need to be *** is believed that revealing the deep influence mechanism between the fractal dimensions and properties of metal material surfaces and interfaces will be the key research direction of the fractal analysis of metal materials in the future.

关键词： metal material surfaces and interfaces fractal analysis fractal dimension homogeneity

SensFL:Privacy-Preserving Vertical Federated Learning with Sensitive Regularization

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 385-404页

作者： Chongzhen Zhang Zhichen Liu Xiangrui Xu Fuqiang Hu Jiao dai Baigen Cai Wei Wang School of Automation and Intelligence Beijing Jiaotong UniversityBeijing100044China Shuohuang Railway Development Co. Ltd.National Energy GroupCangzhou062350China Beijing Key Laboratory of Security and Privacy in Intelligent Transportation School of Computer Science and TechnologyBeijing Jiaotong UniversityBeijing100044China

In the realm of Intelligent Railway Transportation Systems,effective multi-party collaboration is crucial due to concerns over privacy and data *** Federated Learning(VFL)has emerged as a promising approach to facilitate such collaboration,allowing diverse entities to collectively enhance machine learning models without the need to share sensitive training ***,existing works have highlighted VFL’s susceptibility to privacy inference attacks,where an honest but curious server could potentially reconstruct a client’s raw data from embeddings uploaded by the *** vulnerability poses a significant threat to VFL-based intelligent railway transportation *** this paper,we introduce SensFL,a novel privacy-enhancing method to against privacy inference attacks in ***,SensFL integrates regularization of the sensitivity of embeddings to the original data into the model training process,effectively limiting the information contained in shared *** reducing the sensitivity of embeddings to the original data,SensFL can effectively resist reverse privacy attacks and prevent the reconstruction of the original data from the *** experiments were conducted on four distinct datasets and three different models to demonstrate the efficacy of *** results show that SensFL can effectively mitigate privacy inference attacks while maintaining the accuracy of the primary learning *** results underscore SensFL’s potential to advance privacy protection technologies within VFL-based intelligent railway systems,addressing critical security concerns in collaborative learning environments.

关键词： Vertical federated learning privacy defenses

Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 377-384页

作者： Yawei xiao Qianqian Gu Haoyu Li Mengyao Li Yude Wang National Center for International Research on Photoelectric and Energy Materials School of Materials and Energy Yunnan University Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chemical Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** employing electrodeposition to coat MoS2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optimized Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@MoS2(7.5×10～8cm2s-1) surpasses that of most reported V-based ***,MoS2serving as a cathodic armor extends the cycling life of the Zn-CC@BaV6O16·3H2O@MoS2full batteries to over 10000 *** work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.

关键词： Internal electric field Cationic accelerator Ion diffusion kinetics Cathode modification strategy Aqueous zinc ion battery

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang Yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao dai Qi Han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation