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Feeding methods, sleep arrangement, and infant sleep patterns: a Chinese population-based study

World Journal of Pediatrics 2016年第1期12卷 66-75页

作者： xiao-na huang Hui-Shan Wang Jen-Jen Chang Lin-Hong Wang Xi-Cheng Liu Jing-Xiong Jiang Lin An Department of Children Health National Center for Maternal and Children HealthChinese Center for Disease Control and PreventionBeijingChina Department of Epidemiology Saint Louis University College for Public Health and Social JusticeSt.Louis.MOUSA The national Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Bronchoscopy Center Affi liated Children Hospital of Beijing Capital Medical UniversityBeijingChina Department of Public Health Peking University Health Science CenterBeijingChina

Background:Findings from prior research into the effect of feeding methods on infant sleep are *** objectives of this study were to examine infants'sleep patterns by feeding methods and sleep arrangement from birth to eight months ***:This longitudinal cohort study enrolled 524 pregnant women at 34-41 weeks of gestation and their infants after delivery in 2006 and followed up until eight months *** study subjects were recruited from nine women and children hospitals in nine cities in China(Beijing,Chongqing,Wuhan,Changsha,nanning,Xiamen,Xi'an,Jinan,and Hailin).Participating infants were followed up weekly during the first month and monthly from the second to the eighth month after ***-four hour sleep diaries recording infants'sleeping and feeding methods were administered based on caregiver's *** mixed growth curve models were fi tted to estimate the effects of feeding methods and sleep arrangement on infants'sleep patterns over time,controlling for maternal and paternal age,maternal and paternal education level,household income,supplementation of complementary food,and infant birth weight and ***:Exclusively formula fed infants had the greatest sleep percentage/24 h,followed by exclusively breast milk fed infants and partially breast milk fed infants(P<0.01).Night waking followed a similar ***,the differences in sleep percentage and night waking frequency between exclusively formula and exclusively breast milk fed infants weakened over time as infants *** addition,compared to infants with bed-sharing sleep arrangement,those with room sharing sleep arrangement had greater daytime and 24-hour infant sleep percentage,whereas those with sleeping alone sleep arrangement had greater nighttime sleep ***:Our data based on caregiver's selfreport suggested that partial breastfeeding and bedsharing may be associated with less sleep in *** care professio

关键词： breast feeding feeding method infant sleep sleep arrangement

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Outcomes of the national programme on prevention of mother-to-child transmission of hepatitis B virus in China,2016-2017

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Infectious Diseases of Poverty 2019年第4期8卷 102-102页

作者： Ya-Ping Qiao Min Su Yao Song xiao-Yan Wang Zhen Li Yan-Lin Li Li-Xia Dou Qian Wang Katrina Hann Guo-Min Zhang xiao-na huang Yu-Ning Yang Xi Jin Ai-Ling Wang national Centre for Women and Children's Health China CDCBeijingChina 不详

Background:In addition to providing free hepatitis B vaccine(HBvacc)series to all infants in China since 2005,the national programme on prevention of mother-to-child transmission(PMTCT)of hepatitis B virus(HBV)started providing free hepatitis B immunoglobulin for all new-borns born to hepatitis B surface-antigen(HBsAg)positive mothers in ***,few studies have evaluated the effectiveness of the PMTCT ***,we aimed to investigate the outcomes of the programme and identify associated ***:Using a cross-sectional study design,we collected data on 4112 pairs of HBsAg-positive mothers and their children aged 7-22 months in four representative provinces through interviews and medical record *** tested HBsAg and hepatitis B surface antibody(anti-HBs)of children by enzyme-linked immunosorbent assay at designated maternal and child hospital *** used logistic regression to analyse factors associated with child HBsAg and anti-HBs ***:Thirty-five children were HBsAg positive,indicating the mother-to-child transmission(MTCT)rate was 0.9%(0.6-1.1%).The anti-HBs positive rate was 96.8%(96.3-97.4%).Children receiving HBvacc between 12 and 24h of birth were 2.9 times more likely to be infected than those vaccinated in less than 12 h(adjusted odds ratio[aOR]=2.9,95%confidence interval[CI]:1.4-63,P=0.01).Maternal hepatitis B e-antigen(HBeAg)positivity was associated with higher MTCT rate(aOR=79.1,95%Cl:10.8-580.2,Pnation goal,which implies the programme is on track to achieve this *** earlier HBvacc birth dose(HBvcc-BD)was associated with lower MTCT rate,we suggest that the PMTCT programme work with the Expanded Programme on Immunization(EPI)to mod

关键词： Perinatal Birth dose Immunization elimination Vaccination guideline

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肺良性转移性平滑肌瘤4例及文献复习(英文)

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复旦学报（医学版） 2011年第2期38卷 185-188页

作者：李晓亮黄娜高俊刘丹刘韶华杨小东四川大学华西医院呼吸内科成都610041 四川大学华西医院病理科成都610041

Benign metastasizing leiomyoma(BML)is a rare lesion characterized by benign-appearing smooth muscle tumor most frequently occurring

关键词： benign pulmonary metastasizing leiomyoma pulmonary nodule estrogen progesterone

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Exploring the performance of large language models on hepatitis B infection-related questions:A comparative study

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World Journal of Gastroenterology 2025年第3期31卷 103-112页

作者： Yu Li Chen-Kai huang Yi Hu xiao-Dong Zhou Cong He Jia-Wei Zhong Department of Gastroenterology Jiangxi Provincial Key Laboratory of Digestive DiseasesJiangxi Clinical Research Center for GastroenterologyDigestive Disease HospitalThe First Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina HuanKui Academy Nanchang UniversityNanchang 330006Jiangxi ProvinceChina

BACKGROUND Patients with hepatitis B virus(HBV)infection require chronic and personalized care to improve *** language models(LLMs)can potentially provide medical information for *** To examine the performance of three LLMs,ChatGPT-3.5,ChatGPT-4.0,and Google Gemini,in answering HBV-related *** LLMs’responses to HBV-related questions were independently graded by two medical professionals using a four-point accuracy scale,and disagreements were resolved by a third *** question was run three times using three *** was assessed via the Gunning Fog index and Flesch-Kincaid grade *** Overall,all three LLM chatbots achieved high average accuracy scores for subjective questions(ChatGPT-3.5:3.50;ChatGPT-4.0:3.69;Google Gemini:3.53,out of a maximum score of 4).With respect to objective questions,ChatGPT-4.0 achieved an 80.8%accuracy rate,compared with 62.9%for ChatGPT-3.5 and 73.1%for Google *** the six domains,ChatGPT-4.0 performed better in terms of diagnosis,whereas Google Gemini demonstrated excellent clinical ***,in the readability analysis,the mean Gunning Fog index and Flesch-Kincaid grade level scores of the three LLM chatbots were significantly higher than the standard level eight,far exceeding the reading level of the normal *** Our results highlight the potential of LLMs,especially ChatGPT-4.0,for delivering responses to HBV-related *** may be an adjunctive informational tool for patients and physicians to improve ***,current LLMs should not replace personalized treatment recommendations from physicians in the management of HBV infection.

关键词： ChatGPT-3.5 ChatGPT-4.0 Google Gemini Hepatitis B infection Accuracy

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Laparoscopic liver resection utilizing the ventral avascular area of the inferior vena cava:A retrospective cohort study

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World Journal of Gastroenterology 2025年第1期31卷 42-57页

作者： Kun huang Zhu Chen Heng xiao Hai-Yang Hu Xing-Yu Chen Cheng-You Du Xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Department of General Surgery Mianyang Hospital of Traditional Chinese MedicineMianyang 621000Sichuan ProvinceChina

BACKGROUND Laparoscopic liver resection(LLR)can be challenging due to the difficulty of establishing a retrohepatic tunnel under *** the third hepatic hilum before parenchymal transection often leads to significant liver mobilization,tumor compression,and bleeding from the short hepatic veins(SHVs).This study introduces a novel technique utilizing the ventral avascular area of the inferior vena cava(IVC),allowing SHVs to be addressed after parenchymal transection,thereby reducing surgical complexity and improving outcomes in in situ *** To introduce and evaluate a novel LLR technique using the ventral avascular area of the IVC and compare its short-term outcomes with conventional *** The clinical cohort data of patients with pathologically confirmed hepatocellular carcinoma or intrahepatic cholangiocarcinoma who underwent conventional LLR and novel LLR between July 2021 and July 2023 at the First Affiliated Hospital of Chongqing Medical University were retrospectively *** novel LLR,we initially separated the caudate lobe from the IVC using dissecting forceps along the ventral avascular area of the ***,we transected the parenchyma of the left and right caudate lobes from the caudal side to the cephalic side using the avascular area as a ***,we addressed the SHVs and finally dissected the root of the right hepatic vein or left hepatic *** short-term postoperative outcomes and oncological results of the two approaches were evaluated and *** A total of 256 patients were included,with 150(58.59%)undergoing conventional LLR and 106(41.41%)undergoing novel *** novel technique resulted in significantly larger tumor resections(6.47±2.96 cm vs 4.01±2.33 cm,P<0.001),shorter operative times(199.57±60.37 minutes vs 262.33±83.90 minutes,P<0.001),less intraoperative blood loss(206.92±37.09 mL vs 363.34±131.27 mL,P<0.001),and greater resection volume(345.11±31.40 mL vs 264.38±31.98 mL,P<0.001)comp

关键词： Laparoscopic liver resection Inferior vena cava Retrohepatic tunnel Short hepatic veins Complex liver tumors Intraoperative bleeding control

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Effects of Shenqi Xiangyi granules in advanced gastric cancer chemotherapy

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 169-175页

作者： xiao-Jing Shi Yu Song Xue-Xue Liang Ting Chen huang-Yu Hao Xue Han Ya-nan Chen Department of Oncology Zhangjiagang First People's HospitalSuzhou 215600Jiangsu ProvinceChina

BACKGROUND Owing to the absence of specific symptoms in early-stage gastric cancer,most patients are diagnosed at intermediate or advanced *** a result,treatment often shifts from surgery to other therapies,with chemotherapy and targeted therapies being the primary options for advanced gastric cancer treatment.A total of 116 patients with advanced gastric cancer,admitted from January 2021 to December 2023,were selected and divided into two groups of 58 each using the random number table *** control group received FOLFOX4 chemothe-rapy(oxaliplatin+calcium+folinate+5-fluorouracil)combined with intravenous *** observation group received the same treatment as the control group,supplemented by oral administration of Senqi Shiyiwei *** groups underwent treatment cycles of 3 weeks,with a minimum of two *** therapeutic efficacy,immune mechanisms,and treatment-related toxicity and side effects were compared between the *** objective remission rate in the observation group(55.17%)was higher than that of the control group(36.21%)(Pnatural killer cells were lower(Pnally,the incidence of leukopenia,nausea,and vomiting was lower in observed group(P0.05).CONCLUSION Adjuvant therapy with Shenqixian granules may enhance the efficacy of simudizumab combined with FOLFOX4 chemotherapy in advanced gastric cancer and the immune function by increasing immune cell counts,making it a valuable option in clinical treatment.

关键词： Sindilizumab FOLFOX4 chemotherapy Advanced gastric cancer Ginseng Qi Xiangyi granule Clinic treatment

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婴儿期睡眠／觉醒时间的观察

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中华儿科杂志 2009年第7期47卷 499-503页

作者：黄小娜王惠珊刘玺诚蒋竞雄安琳中国疾病预防控制中心妇幼保健中心儿童保健部北京100013 首都医科大学附属北京儿童医院支气管镜中心北京大学医学部公共卫生学院

目的本研究在家庭自然环境下，通过对婴儿生后第一年睡眠／觉醒行为的纵向随访，探索婴儿期睡眠、觉醒时间的发展变化过程。方法研究对象来自全国9个城市，共524名足月健康新生儿，自婴儿生后2d始，通过家长睡眠日记采集新生儿期每周连... 详细信息

目的本研究在家庭自然环境下，通过对婴儿生后第一年睡眠／觉醒行为的纵向随访，探索婴儿期睡眠、觉醒时间的发展变化过程。方法研究对象来自全国9个城市，共524名足月健康新生儿，自婴儿生后2d始，通过家长睡眠日记采集新生儿期每周连续3d，2～12月龄连续7d婴儿睡眠／觉醒行为的相关信息。结果婴儿白天睡眠时间在0～2、3—4、5～6和8—9月龄变化显著，其中生后第1个月发展速率最快，白天睡眠时间构成比从生后2d的82．4％下降至1月龄的62．8％；2、4、6和9月龄的睡眠时间构成比分别为56．6％、48．2％、42．7％和35．7％；白天睡眠次数从生后2d的3．7次减少为12月龄的2次。婴儿夜间连续睡眠能力从生后1个月起逐步增强，4月龄时最长连续睡眠时间延长至6．8h，6月龄后夜醒次数少于0．5次；同时夜晚睡眠时间在4和9月龄时显著增加，夜间睡眠时间构成比从生后2d的55．8％分别增加至4月龄的64．3％和9月龄的71．2％。整体上，婴儿期24h睡眠时间随月龄增加呈下降趋势。结论0～6和8～9月龄是婴儿睡眠／觉醒时间发展的关键阶段。

关键词：睡眠觉醒婴儿日记

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A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： xiao Liang Xingping Quan xiaorui Geng Yujing huang Yonghua Zhao Lei Xi Zhen Yuan Ping Wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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红烧肉加工过程中脂肪降解、氧化和挥发性风味物质的变化研究

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现代食品科技 2017年第3期33卷 257-265页

作者：史笑娜黄峰张良周芳伊赵志磊张春江张泓中国农业科学院农产品加工研究所农业部农产品加工综合性重点实验室北京100193 河北大学质量技术监督学院河北保定071002 中国农业科学院农产品加工研究所主食加工技术研究院黑龙江哈尔滨151900

本文研究了原料肉、料酒腌制、油炸、大火炖煮0.5 h、小火炖煮0.5 h、小火炖煮1 h和成品红烧肉7个不同工艺阶段红烧肉基本理化指标及脂质降解、脂肪氧化和挥发性风味物质的变化状态。结果表明,成品肉水分含量比原料肉显著下降10.5%(p0.0... 详细信息

本文研究了原料肉、料酒腌制、油炸、大火炖煮0.5 h、小火炖煮0.5 h、小火炖煮1 h和成品红烧肉7个不同工艺阶段红烧肉基本理化指标及脂质降解、脂肪氧化和挥发性风味物质的变化状态。结果表明,成品肉水分含量比原料肉显著下降10.5%(p0.05),成品红烧肉时达到最大值为6.29。盐分含量在成品肉时达到最大为0.73%。硫代巴比妥酸值(TBA)在大火炖煮0.5 h后显著增加(p<0.05),然后下降,成品红烧肉时又显著上升(p<0.05),达到了0.62 mg MDA/kg。亚油酸(C18:2)、棕榈酸(C16:0)和硬脂酸(C18:0)是肉中的主要脂肪酸,加工过程中饱和脂肪酸总体呈下降趋势。加工过程中共检出挥发性风味物质86种,其中醛类,脂类和呋喃类是红烧肉中重要的挥发性风味物质。

关键词：红烧肉加工过程脂肪酸脂肪氧化挥发性风味物质

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Sulfolane‑Based Flame‑Retardant Electrolyte for High‑Voltage Sodium‑Ion Batteries

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nano-Micro Letters 2025年第2期17卷 498-516页

作者： Xuanlong He Jie Peng Qingyun Lin Meng Li Weibin Chen Pei Liu Tao huang Zhencheng huang Yuying Liu Jiaojiao Deng Shenghua Ye Xuming Yang Xiangzhong Ren xiaoping Ouyang Jianhong Liu Biwei xiao Jiangtao Hu Qianling Zhang Graphene Composite Research Center College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen 518060People’s Republic of China Center of Electron Microscopy State Key Laboratory of Silicon and Advanced Semiconductor MaterialsSchool of Materials Science and EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China GRINM(Guangdong)Research Institute for Advanced Materials and Technology FoshanGuangdong 528051People’s Republic of China College of Energy Engineering Zhejiang UniversityHangzhouZhejiang 310027People’s Republic of China School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105People’s Republic of China Shenzhen Eigen-Equation Graphene Technology Co.Ltd Shenzhen 518000People’s Republic of China

Sodium-ion batteries hold great promise as next-generation energy storage ***,the high instability of the electrode/electrolyte interphase during cycling has seriously hindered the development of *** particular,an unstable cathode–electrolyte interphase(CEI)leads to successive electrolyte side reactions,transition metal leaching and rapid capacity decay,which tends to be exacerbated under high-voltage ***,constructing dense and stable CEIs are crucial for high-performance *** work reports localized high-concentration electrolyte by incorporating a highly oxidation-resistant sulfolane solvent with non-solvent diluent 1H,1H,5H-octafluoropentyl-1,1,2,2-tetrafluoroethyl ether,which exhibited excellent oxidative stability and was able to form thin,dense and homogeneous *** excellent CEI enabled the O3-type layered oxide cathode naNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)(naNMF)to achieve stable cycling,with a capacity retention of 79.48%after 300 cycles at 1 C and 81.15%after 400 cycles at 2 C with a high charging voltage of 4.2 *** addition,its nonflammable nature enhances the safety of *** work provides a viable pathway for the application of sulfolane-based electrolytes on SIBs and the design of next-generation high-voltage electrolytes.

关键词： Sodium-ion batteries Sulfolane-based electrolyte High voltage Layered oxide cathode Flame retardant

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