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Production line 3D visualization monitoring system design based on OpenGL

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Advances in Manufacturing 2018年第1期6卷 126-135页

作者： Jian-Fei Chai xiao-mei hu He-Wei Qu Ming-Hang Li hui-Jing Xu Yu Liu Tao Yu Shanghai Key Laboratory of Intelligent Manufacture and Robotics School of Mechatronic Engineering andAutomation Shanghai University Shanghai 200072People's Republic of China

New production line management technologiesare required and adopted recently with the development ofmodern manufacturing industry. In this study, a productionline three-dimensional （3D） visualization monitoring sys-tem based on OpenGL modeling, open database connec-tivity （ODBC）, and database management technology isestablished on a VC＋＋6.0 platform to satisfy effectiveproduction. A client/server model is adopted in the system,and data on processing information, interactive operation,and failure process are stored in the server side database. Aclient reads the workpiece process information from theserver, and the machining process of every workpiece isvisually represented in the form of 3D visualization. Pro-duction line 3D visualization provides production capacitysimulation to optimize the parameter settings. Whencompared with the analysis results of production linecapacity, the key parameters possess the same optimalvalues, and this proves the accuracy of production line 3Dvisualization monitoring system. The system provideseffective data support for production line monitoring andmanagement in enterprises.

关键词： Production line Visualization monitoring OpenGL Open database connectivity (ODBC)

Novel deletion mutation in Bruton’s tyrosine kinase results in X-linked agammaglobulinemia:A case report

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World Journal of Clinical Cases 2020年第17期8卷 3859-3866页

作者： xiao-mei hu Ke Yuan Hong Chen Chun Chen Yan-Lan Fang Jian-Fang Zhu Li Liang Chun-Lin Wang Department of Pediatrics The First Affiliated Hospital of Zhejiang UniversityHangzhou 310003Zhejiang ProvinceChina

BACKGROUND X-linked agammaglobulinemia is a primary immunodeficiency disease caused by gene mutations of Bruton’s tyrosine kinase(BTK).We found a new mutation point and summarized the correlation analysis and performed a literature *** SUMMARY The proband was a 5-year-old *** was admitted to our hospital due to a recurrent cough and a fever that had persisted for a *** had a history of multiple respiratory infections and *** was no immunodeficiency or recurrent infection history among his family *** was characterized as follows:Immunoglobulin(Ig)A,90.0 mg/dL(90-450 mg/dL);IgG,20.0 mg/dL(800-1800 mg/dL);and IgM,18.0 mg/dL(60-280 mg/dL).Notably,the assessment of IgG subtypes revealed the following very low levels:Subtype 1,0.26 g/L(3.62-12.28 g/L);subtype 2,0.10 g/L(0.57-2.9 g/L);subtype 3,0.009 g/L(0.129-0.789 g/L);and subtype 4,0.003 g/L(0.013-1.446 g/L).Cellular immunological test results were as follows:CD3,74.6%(50%-84.0%);CD4,47.3%(27.0%-51.0%);and CD8,24.9%(15.0%-44.0%).A de novo hemizygous deletion in BTK was detected:c.902_c.904delAAG/*** levels of the mutant BTK were similar to those of the wild-type gene,though overexpression resulted in markedly reduced levels of mutant BTK(9.49%±1.58%),relative to the wildtype BTK(75.8%±2.98%,P<0.01).CONCLUSION This case of X-linked agammaglobulinemia was attributed to a de novo hemizygous deletion mutation in BTK(c.902_c.904delAAG/p.E301del).The mutation resulted in markedly reduced BTK protein stability in vitro.

关键词： Agammaglobulinemia Bruton’s tyrosine kinase Mutation Immunodeficiency Case report

Teaching Form Reform of "Prevention and Control of Poultry and Poultry Diseases" Course in Higher Vocational Colleges

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Animal husbandry and Feed Science 2011年第3期3卷 45-48页

作者： OUYANG Qing-fang WEI xiao-mei ZENG xiao-hu Jiangxi Biotech Vocational College Nanchang 330200 China

[ Objective] To meet the needs of ＂Prevention and Control of Poultry and Poultry Diseases＂ course in higher vocational colleges in new period. [Method] In order to introduce theoretical knowledge, enhance practical ability and train quality, teaching content, teaching methods and practical teaching of the course were explored according to trends of academic development and personnel training. [ Result] The reform of teaching form improved the teaching effect, mobilized the learning enthusiasm and initiative of students, and enhanced their ability to solve practical prob- lems. [ Conclusion] The teaching form of ＂Prevention and Control of Poultry and Poultry Diseases＂ course has been successfully reformed.

关键词： Prevention and control of poultry and poultry diseases Teaching form Teaching effect

固化工艺对食品罐内涂膜中双酚A二环氧甘油醚分配系数的影响

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食品工业科技 2017年第6期38卷 239-244页

作者：任小玲梅小虎胡英平叶敏立向红华南农业大学食品学院广东广州510642

本文根据Box-Beknhen的中心组合实验设计原理,在单因素实验的基础上,采用三因素三水平的响应曲面分析法,考察烘烤温度、涂膜厚度和烘烤时间对食品罐内涂膜中双酚A二环氧甘油醚(BADGE)的分配系数的影响,建立食品罐内涂膜固化工艺参数优... 详细信息

本文根据Box-Beknhen的中心组合实验设计原理,在单因素实验的基础上,采用三因素三水平的响应曲面分析法,考察烘烤温度、涂膜厚度和烘烤时间对食品罐内涂膜中双酚A二环氧甘油醚(BADGE)的分配系数的影响,建立食品罐内涂膜固化工艺参数优化的二次多项式数学模型。结果表明:三因素影响程度大小次序为:涂膜厚度>烘烤温度>烘烤时间,且三因素两两交互作用均为极显著(p<0.01),最优固化工艺为:烘烤温度200℃、涂膜厚度12 g/m^2、烘烤时间12 min,此时BADGE的分配系数值为2313.04,且与实验值较为接近。说明该响应面得到的工艺参数准确可靠,对提高食品罐的安全性具有一定的指导意义。

关键词： BADGE 分配系数固化工艺响应面法食品罐内涂膜

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辣木叶多糖结构及其降血糖功效研究

粮食与油脂 2024年第4期37卷 129-134页

作者：何萍冯伟聂健梅小虎冯晓丽广东岭南职业技术学院广东广州511510

以辣木叶多糖(MOP)为研究对象,通过H2O2-维生素C法制备4种低相对分子质量的辣木叶多糖(MOP-1、MOP-2、MOP-3和MOP-4),研究其降血糖能力,并从多糖结构上分析其活性差异原因。结果表明:MOP-4对α-淀粉酶和α-葡萄糖苷酶有最强的抑制能力,... 详细信息

以辣木叶多糖(MOP)为研究对象,通过H2O2-维生素C法制备4种低相对分子质量的辣木叶多糖(MOP-1、MOP-2、MOP-3和MOP-4),研究其降血糖能力,并从多糖结构上分析其活性差异原因。结果表明:MOP-4对α-淀粉酶和α-葡萄糖苷酶有最强的抑制能力,而MOP对α-淀粉酶和α-葡萄糖苷酶抑制效果最差。对MOP和MOP-4进行结构表征,发现MOP和MOP-4的官能团和糖苷键种类未发生变化,但糖苷键数量比例发生变化,造成差示扫描量热(DSC)有差异,且影响多糖颗粒大小及表面结构。MOP-4多糖颗粒更为细腻、含有更多的活性Galp-(1,3→糖残基),可作为具有降血糖功效的食品添加剂。

关键词：辣木叶多糖结构降血糖功效

Exploring the performance of large language models on hepatitis B infection-related questions:A comparative study

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World Journal of Gastroenterology 2025年第3期31卷 103-112页

作者： Yu Li Chen-Kai huang Yi hu xiao-Dong Zhou Cong He Jia-Wei Zhong Department of Gastroenterology Jiangxi Provincial Key Laboratory of Digestive DiseasesJiangxi Clinical Research Center for GastroenterologyDigestive Disease HospitalThe First Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina huanKui Academy Nanchang UniversityNanchang 330006Jiangxi ProvinceChina

BACKGROUND Patients with hepatitis B virus(HBV)infection require chronic and personalized care to improve *** language models(LLMs)can potentially provide medical information for *** To examine the performance of three LLMs,ChatGPT-3.5,ChatGPT-4.0,and Google Gemini,in answering HBV-related *** LLMs’responses to HBV-related questions were independently graded by two medical professionals using a four-point accuracy scale,and disagreements were resolved by a third *** question was run three times using three *** was assessed via the Gunning Fog index and Flesch-Kincaid grade *** Overall,all three LLM chatbots achieved high average accuracy scores for subjective questions(ChatGPT-3.5:3.50;ChatGPT-4.0:3.69;Google Gemini:3.53,out of a maximum score of 4).With respect to objective questions,ChatGPT-4.0 achieved an 80.8%accuracy rate,compared with 62.9%for ChatGPT-3.5 and 73.1%for Google *** the six domains,ChatGPT-4.0 performed better in terms of diagnosis,whereas Google Gemini demonstrated excellent clinical ***,in the readability analysis,the mean Gunning Fog index and Flesch-Kincaid grade level scores of the three LLM chatbots were significantly higher than the standard level eight,far exceeding the reading level of the normal *** Our results highlight the potential of LLMs,especially ChatGPT-4.0,for delivering responses to HBV-related *** may be an adjunctive informational tool for patients and physicians to improve ***,current LLMs should not replace personalized treatment recommendations from physicians in the management of HBV infection.

关键词： ChatGPT-3.5 ChatGPT-4.0 Google Gemini Hepatitis B infection Accuracy

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固化工艺对食品罐内涂双酚A分配系数的影响

包装工程 2017年第13期38卷 66-71页

作者：梅小虎任小玲孙魁魁叶敏立向红华南农业大学广州510642

目的研究食品罐内涂膜的固化工艺对涂膜中双酚A迁移分配系数的影响。方法在单因素实验的基础上,采用响应面分析法对固化工艺参数进行优化分析,使得双酚A的分配系数最大。结果三因素对迁移物双酚A分配系数的影响主次顺序为涂膜量>固化温... 详细信息

目的研究食品罐内涂膜的固化工艺对涂膜中双酚A迁移分配系数的影响。方法在单因素实验的基础上,采用响应面分析法对固化工艺参数进行优化分析,使得双酚A的分配系数最大。结果三因素对迁移物双酚A分配系数的影响主次顺序为涂膜量>固化温度>固化时间,其中固化温度和涂膜量对双酚A迁移的影响极为显著(P<0.0001),且固化温度与固化时间之间,涂膜量与固化时间之间的交互作用极为显著(P<0.0001)。在固化温度为200℃,涂膜量为12 g/m^2,固化时间为12 min条件下,双酚A迁移的分配系数最大,为5993.02。结论最佳工艺条件下得到的分配系数与实验值较为接近,说明该响应面得到的工艺参数准确可靠,确保了BPA食品罐的安全性。

关键词：双酚A 分配系数固化工艺食品罐内涂膜响应面法

Computed tomography enterography-based radiomics for assessing mucosal healing in patients with small bowel Crohn's disease

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World Journal of Gastroenterology 2025年第3期31卷 62-72页

作者： Hao Ding Yuan-Yuan Fang Wen-Jie Fan Chen-Yu Zhang Shao-Fei Wang Jing hu Wei Han Qiao mei Department of Gastroenterology The First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Radiation Oncology The First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Gastroenterology Suzhou First People's HospitalSuzhou 234099Anhui ProvinceChina

BACKGROUND Mucosal healing(MH)is the major therapeutic target for Crohn's disease(CD).As the most commonly involved intestinal segment,small bowel(SB)assessment is crucial for CD ***,it poses a significant challenge due to its limited accessibility through conventional endoscopic *** To establish a noninvasive radiomic model based on computed tomography enterography(CTE)for MH assessment in SBCD *** Seventy-three patients diagnosed with SBCD were included and divided into a training cohort(n=55)and a test cohort(n=18).Radiomic features were obtained from CTE images to establish a radiomic *** demographics were analysed to establish a clinical model.A radiomic-clinical nomogram was constructed by combining significant clinical and radiomic *** diagnostic efficacy and clinical benefit were evaluated via receiver operating characteristic(ROC)curve analysis and decision curve analysis(DCA),*** Of the 73 patients enrolled,25 patients achieved *** radiomic-clinical nomogram had an area under the ROC curve of 0.961(95%confidence interval:0.886-1.000)in the training cohort and 0.958(0.877-1.000)in the test cohort and provided superior clinical benefit to either the clinical or radiomic models alone,as demonstrated by *** These results indicate that the CTE-based radiomic-clinical nomogram is a promising imaging biomarker for MH and serves as a potential noninvasive alternative to enteroscopy for MH assessment in SBCD patients.

关键词： Crohn’s disease Computed tomography enterography Mucosal healing Nomogram Radiomics

Laparoscopic liver resection utilizing the ventral avascular area of the inferior vena cava:A retrospective cohort study

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World Journal of Gastroenterology 2025年第1期31卷 42-57页

作者： Kun huang Zhu Chen Heng xiao Hai-Yang hu Xing-Yu Chen Cheng-You Du Xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Department of General Surgery Mianyang Hospital of Traditional Chinese MedicineMianyang 621000Sichuan ProvinceChina

BACKGROUND Laparoscopic liver resection(LLR)can be challenging due to the difficulty of establishing a retrohepatic tunnel under *** the third hepatic hilum before parenchymal transection often leads to significant liver mobilization,tumor compression,and bleeding from the short hepatic veins(SHVs).This study introduces a novel technique utilizing the ventral avascular area of the inferior vena cava(IVC),allowing SHVs to be addressed after parenchymal transection,thereby reducing surgical complexity and improving outcomes in in situ *** To introduce and evaluate a novel LLR technique using the ventral avascular area of the IVC and compare its short-term outcomes with conventional *** The clinical cohort data of patients with pathologically confirmed hepatocellular carcinoma or intrahepatic cholangiocarcinoma who underwent conventional LLR and novel LLR between July 2021 and July 2023 at the First Affiliated Hospital of Chongqing Medical University were retrospectively *** novel LLR,we initially separated the caudate lobe from the IVC using dissecting forceps along the ventral avascular area of the ***,we transected the parenchyma of the left and right caudate lobes from the caudal side to the cephalic side using the avascular area as a ***,we addressed the SHVs and finally dissected the root of the right hepatic vein or left hepatic *** short-term postoperative outcomes and oncological results of the two approaches were evaluated and *** A total of 256 patients were included,with 150(58.59%)undergoing conventional LLR and 106(41.41%)undergoing novel *** novel technique resulted in significantly larger tumor resections(6.47±2.96 cm vs 4.01±2.33 cm,P<0.001),shorter operative times(199.57±60.37 minutes vs 262.33±83.90 minutes,P<0.001),less intraoperative blood loss(206.92±37.09 mL vs 363.34±131.27 mL,P<0.001),and greater resection volume(345.11±31.40 mL vs 264.38±31.98 mL,P<0.001)comp

关键词： Laparoscopic liver resection Inferior vena cava Retrohepatic tunnel Short hepatic veins Complex liver tumors Intraoperative bleeding control