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Chinese Chemical Letters 2015年第1期26卷 124-128页

作者： Wei Wei ling-xiao song Lin Guo School of Chemistry and Chemical Engineering Shangqiu Normal University School of Chemistry and Environment Beijing University of Aeronautics & Astronautics College of Chemistry and Molecular Engineering Zhengzhou University

SnO2 hollow nanospheres were successfully synthesized via a facile one-step solvothermal *** show that the as-prepared SnO2 spheres are of hollow structure with a diameter at around 50 nm,and especially,the shell of the spheres is assembled by single layer SnO2 *** surface area of the material reaches up to 202.5 m^2/*** an anode material for Li ion batteries,the sample exhibited improved electrochemical performance compared with commercial SnO2 *** cycled at high current rate of 0.5 C,1 C and 0.5 C for 20 cycles,respectively,the electrode can maintain a capacity of 509 mAh/*** suitable shell thickness/diameter ratio endows the good structural stability of the material during cycling,which promises the excellent cycling performance of the *** large surface area and the ultra thin shell ensure the high rate performance of the material.

关键词： SnO2 Hollow nanospheres Single layer Li ion batteries

Colonoscopy-induced acute appendicitis: A case report

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World Journal of Clinical Cases 2023年第36期11卷 8563-8567页

作者： xiao-ling song Jin-You Ma Zhi-Gao Zhang Department of Gastroenterology Sunshine Union HospitalWeifang 261000Shandong ProvinceChina

BACKGROUND Colonoscopy is widely used for examination,diagnosis,and treatment because of its low incidence of associated ***-colonoscopy appendicitis(PCA)is very rare and is easily misdiagnosed as electrocoagulation syndrome or colon ***,clinicians should pay close attention to this *** SUMMARY A 47-year-old female patient underwent a colonoscopy for a systematic physical examination,and the procedure was uneventful with normal endoscopic and histologic ***,the bowel preparation was suboptimal(Boston 2-3-2).After the examination,the patient experienced pain in the lower abdomen,which progressively *** tomography of the lower abdomen and pelvis revealed appendiceal calcular obstruction and *** the patient refused surgery,she was managed with antibiotics and recovered *** In the current literature,the definition of PCA remains ***,abdominal pain after colonoscopy should be differentiated from acute appen-dicitis.

关键词： Colonoscopy Complications Appendicitis Differential diagnosis Case report

抗草甘膦转基因油菜和野芥菜回交1代子2代-子6代在无除草剂选择压下的适合度

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Journal of Plant Ecology 2024年第1期17卷 135-147页

作者： Lei Huang Zi-Cheng Shao ling-ling Dai Ai-Qin Zheng Qing-ling Zhang xiao-Lei Wang Sheng Qiang xiao-ling song Weed Research Laboratory College of Life SciencesNanjing Agricultural UniversityNanjing 210095China

抗草甘膦转基因油菜和野芥菜回交1代子2代-子6代在无除草剂选择压下的适合度转基因作物的抗性基因能否成功渗入野生或近缘杂草取决于携带转基因回交后代的适合度。为深入了解转基因油菜(Brassica napus)向野芥菜(wild ***)基因流动的生... 详细信息

抗草甘膦转基因油菜和野芥菜回交1代子2代-子6代在无除草剂选择压下的适合度转基因作物的抗性基因能否成功渗入野生或近缘杂草取决于携带转基因回交后代的适合度。为深入了解转基因油菜(Brassica napus)向野芥菜(wild ***)基因流动的生态风险,本文研究了在低密度(5株/m^(2))和高密度(10株/m^(2))下,以及单种和混合种植(野芥菜:BC1F2R-BC1F6R=1:1)下抗草甘膦转基因油菜与野芥菜回交1代子2代到子6代(BC1F2R-BC1F6R)的适合度;并分析回交后代的适合度成分、种植密度和种植方式之间的相关性。研究结果表明:在单种低密度下,与野芥菜相比,回交1代子2代(BC1F2R)和子3代(BC1F3R)具有较低的适合度,而回交1代子4代-子6代(BC1F4R-BC1F6R)具有较高的适合度;无论是单种还是混种,高密度下所有回交后代的适合度均低于野芥菜。相关性分析结果显示,种植密度和种植方式对回交后代(BC1F2R-BC1F6R)的适合度成分有显著影响。这些结果表明,转基因从栽培油菜渗入到野芥菜很大程度上取决于回交后代的特定生长环境。

关键词：野芥菜抗草甘膦转基因油菜回交后代适合度基因漂移

An experimental study of microwave tissue coagulation on SD-rat submandibular gland tumor

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中国口腔颌面外科杂志 2008年第B5期6卷 125-126页

作者： Shu Zhong Xing Hong Bin Jiang xiao ling song Department of Oral and Maxillofacial Surgery Affiliated Stomatological Hospital Nanjing Medical University Nanjing 210029 China Department of Oral Pathology Affiliated Stomatological Hospital Nanjing Medical University Nanjing 210029 China

Application of single balloon enteroscopy-assisted therapeutic endoscopic retrograde cholangiopancreatography in patients after bilioenteric Roux-en-Y anastomosis: Experience of multi-disciplinary collaboration

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World Journal of Gastroenterology 2019年第36期25卷 5505-5514页

作者： Wen-Guang Wu Lu-Cui Qin xiao-ling song Ming-Ning Zhao Wen-Jie Zhang Jun Gu Hao Weng Ying-Bin Liu Yi Zhang Chun-Ying Qu Lei-Ming Xu Xue-Feng Wang Department of General Surgery and Laboratory of General Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200092 China Department of Operating Room Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200092 China Shanghai Key Laboratory of Biliary Tract Disease Research Shanghai 200092 China Department of Gastroenterology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200092 China

BACKGROUND Bilioenteric Roux-en-Y anastomosis is one of the most complicated approaches for reconstructing the gastrointestinal tract, and endoscopic retrograde cholangiopancreatography (ERCP) is technically challenging in patients after bilioenteric Roux-en-Y anastomosis. The optimal endoscopic strategies for such cases remain unknown. AIM To explore the feasibility and effectiveness of single balloon enteroscopy-assisted (SBE-assisted) therapeutic ERCP in patients after bilioenteric Roux-en-Y anastomosis based on multi-disciplinary collaboration between endoscopists and surgeons as well as report the experience from China. METHODS This is a single center retrospective study. All of the SBE-assisted therapeutic ERCP procedures were performed by the collaboration between endoscopists and surgeons. The operation time, success rate, and complication rate were calculated. RESULTS Forty-six patients received a total of 64 SBE-assisted therapeutic ERCP procedures, with successful scope intubation in 60 (93.8%) cases and successful diagnosis in 59 (92.2%). All successfully diagnosed cases received successful therapy. None of the cases had perforation or bleeding during or after operation, and no post-ERCP pancreatitis occurred. CONCLUSION Based on multi-disciplinary collaboration, SBE-assisted therapeutic ERCP in patients after bilioenteric Roux-en-Y anastomosis is relatively safe and effective and has a high success rate.

关键词： Bilioenteric Roux-en-Y anastomosis Single balloon enteroscopy Multidisciplinary cooperation Hepaticojejunostomy Pancreaticoduodenectomy

Modified FOLFIRINOX for unresectable locally advanced or metastatic gallbladder cancer,a comparison with GEMOX regimen

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Hepatobiliary Surgery and Nutrition 2021年第4期10卷 498-506页

作者： Xu-Ya Cui Xue-Chuan Li Jiu-Jie Cui Xiang-song Wu Lu Zou xiao-ling song Tai Ren Yi-Di Zhu Huai-Feng Li Yang Yang Ke Liu Xu-Sheng Han Zi-Yao Jia Wen-Guang Wu Xu-An Wang Wei Gong Li-Wei Wang Mao-Lan Li Ying-Bin Liu Department of General Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Biliary-Pancreatic Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Biliary Tract Disease Research ShanghaiChina State Key Laboratory of Oncogenes and Related Genes ShanghaiChina Shanghai Research Center of Biliary Tract Disease ShanghaiChina Shanghai Cancer Institute ShanghaiChina Department of Medical Oncology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Background:The first-line chemotherapy regimen for advanced gallbladder cancer(GBC)is gemcitabine plus platinum(GP),despite its efficacy is *** current investigation is a retrospective study to compare the safety and efficacy between the modified FOLFIRINOX(mFOLFIRINOX)and gemcitabine plus oxaliplatin(GEMOX)as the first-line chemotherapy for unresectable locally advanced or metastatic ***:The data of patients with unresectable locally advanced or metastatic GBC,who were treated with mFOLFIRINOX or GEMOX as the first-line therapy between April 2014 and April 2018 at Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,were *** retrospective study evaluated the clinical characteristics,survival outcomes and adverse ***:A total of 44 patients(n=25 in mFOLFIRINOX,n=19 in GEMOX)were *** were no significant differences between groups in baseline *** median progression free survival(mPFS)was 5.0 months in the mFOLFIRINOX group and 2.5 months in the GEMOX group[P=0.021;hazard ratio(HR),0.499;95%CI,0.266 to 0.937].The median overall survival(mOS)was 9.5 months in the mFOLFIRINOX group and 7.0 months in the GEMOX group(P=0.019;HR,0.471;95%CI,0.239 to 0.929).Disease control rate(DCR)was 76.0%in the mFOLFIRINOX group and 47.4%in the GEMOX group(P=0.051).The rate of grade 3-4 adverse events was 48%in the mFOLFIRINOX group and 36.8%in the GEMOX group(P=0.459).The incidence of grade 3-4 neutropenia and diarrhea were more common in the mFOLFIRINOX group,while the incidence of grade 3-4 thrombocytopenia and peripheral neuropathy were more common in the GEMOX ***:mFOLFIRINOX might improve the poor prognosis of unresectable locally advanced or metastatic GBC,and the results need to be further verified by prospective clinical studies.

关键词： Gallbladder cancer(GBC) modified FOLFIRINOX(mFOLFIRINOX) gemcitabine plus oxaliplatin(GEMOX) chemotherapy

Cross-reactivity of hypervariable region 1 chimera of hepatitis C virus

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World Journal of Gastroenterology 2003年第6期9卷 1256-1260页

作者： Bing-Shui Xiu Shi-Gan ling xiao-Guo song He-Qiu Zhang Kun Chen Cui-Xia Zhu Laboratory of Molecular Virology,Institute of Basic Medical Sciences,Academy of Military Medical Sciences,Beijing 100850,China Laboratory of Molecular Virology Institute of Basic Medical Sciences Academy of Military Medical Sciences Beijing 100850 P.R.China.

AIM: To analyze the amino acid sequences of hypervariable region 1 (HVR1) of HCV isolates in China and to construct a combinatorial chimeric HVR1 protein having a very broad high cross-reactivity.METHODS: All of the published HVR1 sequences from China were collected and processed with a computer *** representative HVR1's sequences were formulated based on a consensus profile and homology within certain subdivision. A few reported HVR1 mimotope sequences were also included for a broader representation. All of them were cloned and expressed in ***. The cross-reactivity of the purified recombinant HVR1 antigens was tested by ELISA with a panel of sera from HCV infected patients in *** of them were further ligated together to form a combinatorial HVR1 chimera.RESULTS: Altogether 12 HVR1s were selected and expressed in E. coli and purified to homogeneity. All of these purified antigens showed some cross-reactivity with sera in a 27 HCV positive panel. Recombinant HVR1s of No. 1, 2, 4, and 8# showing broad cross-reactivities and complementarity with each other, were selected for the ligation elements. The chimera containing these 4 HVR1s was highly expressed in E. coli. The purified chimeric antigen could react not only with all the HCV antibody positive sera in the panel but also with 90/91 sera of HCV -infected patients.CONCLUSION: The chimeric antigen was shown to have a broad cross-reactivity. It may be helpful for solving the problem caused by high variability of HCV, and in the efforts for a novel vaccine against the virus.

关键词：丙型肝炎病毒超变量区域1 基因序列分析交叉反应性嵌合体抗原

Passive activity enhances residual control ability in patients with complete spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing xiao Mingming Gao Zejia He Jia Zheng Hongming Bai Jia-Sheng Rao Guiyun song Wei song xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

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医用电子内窥镜畸变实时校正系统的视频控制

天津大学学报（自然科学与工程技术版） 2004年第12期37卷 1073-1076页

作者：陈晓冬宋玲玲张树华谢洪波郁道银天津大学精密仪器与光电子工程学院光电信息技术科学教育部重点实验室天津300072

针对内窥镜系统光学畸变问题,提出了医用电子内窥镜畸变实时校正系统的原理和硬件系统的实现.系统采用基于点阵样板的校正方法,拟合理想像与实际像的关系,完成像素点的几何位置校正和灰度校正;采用FP GA作为控制中心,设计了I2C串行总线... 详细信息

针对内窥镜系统光学畸变问题,提出了医用电子内窥镜畸变实时校正系统的原理和硬件系统的实现.系统采用基于点阵样板的校正方法,拟合理想像与实际像的关系,完成像素点的几何位置校正和灰度校正;采用FP GA作为控制中心,设计了I2C串行总线通信,协调了解码器与编码器的同步控制,最终利用硬件实现了畸变实时校正功能.图像采样频率13.5MHz,帧频达25帧/s.

关键词：医用电子内窥镜畸变实时校正编码器视频控制

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MR阻尼器的半主动控制研究

力学季刊 2001年第4期22卷 471-476页

作者：任晓崧凌海梅同济大学结构工程与防灾研究所上海200092

MR阻尼器能提供可以调节的阻尼力,适合用作减少结构地震响应的半主动控制器。本文对MR阻尼器的半主动控制进行研究,提出了状态跳跃控制算法,根据结构响应的大小实现MR阻尼器的状态切换,使结构响应得到有效的控制。这种控制策略简便,不... 详细信息

MR阻尼器能提供可以调节的阻尼力,适合用作减少结构地震响应的半主动控制器。本文对MR阻尼器的半主动控制进行研究,提出了状态跳跃控制算法,根据结构响应的大小实现MR阻尼器的状态切换,使结构响应得到有效的控制。这种控制策略简便,不需要在线计算,便于实施。由于速度响应直接影响MR阻尼器的阻尼力,建议用速度响应作为MR阻尼器进行状态切换的变量。文中给出了两个算例,进行了计算分析和比较,说明了状态跳跃控制算法的特点。

关键词： MR阻尼器阻尼力状态跳跃控制算法结构响应状态切换速度响应结构控制半主动控制系统 MR液体