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Clinical study of anesthetization by dezocine combined with propofol for indolent colonoscopy

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World Journal of Gastroenterology 2016年第24期22卷 5609-5615页

作者： Bin-Bin Xu xiao-liang zhao Gui-ping Xu Department of Endoscopy Center People’s Hospital of Xinjiang Uygur Autonomous Region

AIM: To assess the use of dezocine combined with propofol for the anesthetization of patients undergoing indolent ***: A cross-sectional survey of patients undergoing indolent colonoscopy in the Xinjiang people's Hospital was conducted from April 1 to April 30, 2015. The survey collected patient general information and anesthesia data, including overall medical experience and pain management. Thirty minutes after colonoscopy surgery, samples of venous blood were collected and the biochemical indicators of gastrointestinal function were analyzed. RESULTS: There were 98 female and 62 male respondents. Indolent colonoscopy was found to be more suitable for mid to older-aged patients. The necessary conditions for the diagnosis of digestive diseases were required in 65 of the 73 inpatients. Adverse reactions to the intraoperative process included two cases of body movement and two cases of respiratory depression. Gastrin and vasoactive intestinal peptide levels were slightly increased. However, somatostatin and endothelin levels were slightly decreased. CONCLUSION: This study revealed that dezocine combined with propofol can be successfully used for the anesthetization of indolent colonoscopy patients without pain and should be widely used.

关键词： Dezocine propofol Colonoscopy patient assessment Anesthetization Cross-sectional

Intraneuronal accumulation of Aβ42 induces age-dependent slowing of neuronal transmission in Drosophila

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Neuroscience Bulletin 2014年第2期30卷 185-190页

作者： Jing-Ya Lin Wen-An Wang xiao Zhang Hai-Yan Liu xiao-liang zhao Fu-De Huang Department of Neurology Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Center for Stem Cell and Nanomedicine Laboratory for System Biology Shanghai Advanced Research Institute Chinese Academy of Sciences Department of Neurology Xin Hua Hospital Affiliated to Shanghai Jiaotong University School of Medicine Chongming Branch Institute of Neuroscience and State Key Laboratory of Neuroscience Shanghai Institutes for Biological Sciences Chinese Academy of Sciences

Beta amyloid （Aβ42）-induced dysfunction and loss of synapses are believed to be major underlying mechanisms for the progressive loss of learning and memory abilities in Alzheimer＇s disease （AD）. The vast majority of investigations on AD-related synaptic impairment focus on synaptic plasticity, especially the decline of long-term potentiation of synaptic transmission caused by extracellular Aβ42. Changes in other aspects of synaptic and neuronal functions are less studied or undiscovered. Here, we report that intraneuronal accumulation of Aβ42 induced an age- dependent slowing of neuronal transmission along pathways involving multiple synapses.

关键词： neuronal transmission synaptic dysfunction latency Alzheimer's disease intraneuronal betaamyloid

A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： xiao liang Xingping Quan xiaorui Geng Yujing Huang Yonghua zhao Lei Xi Zhen Yuan Ping Wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

Study on the Formation Mechanism of the Solid Siliconized Layer on TJ-48A1 Alloy

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材料热处理学报 2004年第5期 681-683页

作者： MA xiao-xia, liang Wei, zhao Xing-guo, SHI Ju-yan, BIAN Li-ping School of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, China

The microstructures of the siliconized specimens of Ti-48Al alloy were analyzed by SEM equipped with XEDS. The specimens were pack siliconized with the two different cementations, 15%Si+85% A12O3 and 15%Si+85%ZrO2. The results show that a composite siliconized layer is formed on the surface of the TiAl alloy. The outer layer is the continuous A12O3 where a lot of Si particles adhered; the inner layer is most of Ti5Si3 with amount of ALjOs particles dispersed in. It was deduced that the A12O3 in the cementation layer is formed by the Al atoms in the TiAl substrate react with the residual O in the furnace and in the TiAl substrate.

关键词： Ti-48Al alloy chemical heat-treatment siliconization microstructure

Radiofrequency catheter ablation of idiopathic ventricular tachycardia and symptomatic premature ventricular contraction originating from valve annulus

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Chinese Medical Journal 2008年第22期121卷 2241-2245页

作者： WU xiao-yu liang zhao-guang TAN Zhen GU Hong-yue ZHANG Shu LI Wei-min Department of Cardiology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiangl50001 China

Background Radiofrequency catheter ablation （RFCA） has been established as an effective and curative therapy for ventricular tachycardia （VT） and severely symptomatic premature ventricular contraction （PVC） from the outflow tract in structurally normal hearts. This study aimed to investigate electrophysiologic characteristics and effects of RFCA for patients with idiopathic VT and symptomatic PVC originating from the valve annulus. Methods Characteristics of body surface electrocardiogram （ECG） and endocardiogram in a successful RFCA target were analyzed in 16 patients with idiopathic VT and symptomatic PVC originating from the valve annulus. Additionally, the ECG characteristics of VT or PVC were compared with those of manifest Wolff-Parkinson-White （WPW） syndrome originating from the same site of origin in 15 patients. Results Thirteen patients were successful, 2 recurrent and 1 failed. The recurrent cases underwent successful ablation the second time guided by the Ensite 3000 mapping system. In all patients with the WPW syndrome, the characteristics of QRS morphology were well matched with those of the VT and PVC that originated from corresponding sites of origin. Conclusions RFCA is an effective curative therapy for VT and There are specific characteristics in ECG and the ablation site accessory pathway＇s algorithm. symptomatic PVC originating from the valve annulus. could be located by means of the WPW syndrome

关键词： ventricular tachycardia valve annulus radiofrequency catheter ablation

Establishing a new testing protocol of the electrochemical stability window for electric double-layer capacitors

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Science China Chemistry 2025年第1期68卷 217-225页

作者： Ruilin Hou xiaoxi zhao Tingting liang Qingyun Dou Shan Xu Xingbin Yan School of Materials Science and Engineering Sun Yat-sen University Laboratory of Clean Energy Chemistry and Materials Lanzhou Institute of Chemical Physics Chinese Academy of Sciences College of Engineering and Applied Sciences Nanjing University Center of Industrial Analysis and Testing Guangdong Academy of Science

The electrochemical stability window(ESW) is crucial for determining the energy density of electric double-layer capacitors(EDLCs). However, current ESW testing protocols of EDLCs are strongly affected by artificial factors, thereby leading to unreliable result. To solve this problem, we first identify the key shortcomings of the traditional protocols by analyzing their test principles. Subsequently, taking an aqueous carbon-based EDLC as an example, we design a side reaction descriptor to represent the response difference in the charging capacitance to side reactions between the cyclic voltammetry and galvanostatic chargedischarge methods. With the aid of this descriptor, we propose a new ESW testing protocol, which is not only able to completely avoid the adverse influence of subjective factors but also fully consider the operating condition limitations. The protocol can be extended from the single electrode to the full device. This work proposes a more rigorous definition of ESW and provides a reliable protocol for evaluating the ESW of EDLCs.

关键词： electric double-layer capacitors electrochemical stability window testing protocol side reaction descriptor operating limitation

CRC-AIDED TURBO EQUALIZATION FOR MIMO FREQUENCY SELECTIVE FADING CHANNELS

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Journal of Electronics(China) 2007年第1期24卷 69-74页

作者： Liu Zhanli liang xiao zhao Chunming Wang Jing National Mobile Commun. Research Lab. Southeast Univ. Nanjing i10096 China SEUCOMM Corporation Ltd Nanjing 2100P6 China

This paper presents a CRC (Cyclic Redundancy Check)-aided turbo equalization approach to reduce the computational complexity. In this approach,CRC code bits are padded to the end of each transmit block,and a cyclic redundancy check is performed after decoding each block at the receiver end. If the check sum is zero,which means the receive block is correct,the corresponding LLRs (Log Likelihood Ratios) of this block are set high reliable values,and all the computations corresponding to this block can be cancelled for the subsequent outer iterations. With a lower computational complexity the proposed approach can achieve the same as or even better performance than the conventional non-CRC method.

关键词： Cyclic Redundancy Check (CRC) Turbo equalization Multi-Input Multi-Output (MIMO)

COMPrompter: reconceptualized segment anything model with multiprompt network for camouflaged object detection

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Science China(Information Sciences) 2025年第1期68卷 189-203页

作者： xiaoqin ZHANG Zhenni YU Li zhao Deng-Ping FAN Guobao xiao Zhejiang Province Key Laboratory of Intelligent Informatics for Safety and Emergency Wenzhou University Nankai International Advanced Research Institute (SHENZHEN FUTIAN) College of Computer Science Nankai University School of Computer Science and Technology Tongji University

We rethink the segment anything model(SAM) and propose a novel multiprompt network called COMPrompter for camouflaged object detection(COD). SAM has zero-shot generalization ability beyond other models and can provide an ideal framework for COD. Our network aims to enhance the single prompt strategy in SAM to a multiprompt strategy. To achieve this, we propose an edge gradient extraction module, which generates a mask containing gradient information regarding the boundaries of camouflaged objects. This gradient mask is then used as a novel boundary prompt, enhancing the segmentation process. Thereafter, we design a box-boundary mutual guidance module, which fosters more precise and comprehensive feature extraction via mutual guidance between a boundary prompt and a box prompt. This collaboration enhances the model's ability to accurately detect camouflaged objects. Moreover, we employ the discrete wavelet transform to extract high-frequency features from image embeddings. The high-frequency features serve as a supplementary component to the multiprompt ***, our COMPrompter guides the network to achieve enhanced segmentation results, thereby advancing the development of SAM in terms of COD. Experimental results across COD benchmarks demonstrate that COMPrompter achieves a cutting-edge performance, surpassing the current leading model by an average positive metric of 2.2% in COD10K. In the specific application of COD, the experimental results in polyp segmentation show that our model is superior to top-tier methods as well. The code will be made available at https://***/guobaoxiao/COMPrompter.

关键词： segment anything model camouflaged object detection boundary prompt

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Experimental study of dual nano-network, high-temperature resistant aerogel material as an integration of thermal management functions

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Journal of Energy Chemistry 2025年第1期100卷 157-170页

作者： Yueyue xiao Tianke Mao Zun zhao Yuelei Pan Heping Zhang Xudong Cheng State Key Laboratory of Fire Science University of Science and Technology of China

Thermal management system is highly desirable to guarantee the performance and thermal safety of lithium-ion batteries,but it reduces the energy density of battery modules and even is unable to provide highly effective ***,a thermal management function integrated material is presented based on high-temperature resistant aerogel and phase change material and is applied at both charge–discharge process and thermal runaway *** this sandwich structure Paraffin@SiC nanowire/Aerogel sheet （denoted as PA@SAS） system,SiC nanowires endow the middle aerogel sheet （SAS） a dual nano-network *** enhanced mechanical properties of SAS were studied by compressive tests and dynamic mechanical ***,the thermal conductivity of SAS at 600°C is only 0.042 W/（m K）.The surface phase change material layers facilitate temperature uniformity of batteries （surface temperature difference less than 1.82°C） through latent ***,a large-format battery module with four 58 Ah LiNi0.5Co0.2Mn0.3O2LIBs was ***@SAS successfully prevents thermal runaway propagation,yielding a temperature gap of 602°C through the 2 mm-thick cross ***@SAS also exhibits excellent performance in other safety issues such as temperature rise rate,flame heat flux,*** lightweight property and effective insulation performance achieves significant safety enhancement with mass and volume energy density reduction of only 0.79%and 5.4%,*** originality of the present research stems from the micro and macro structure design of the proposed thermal management material and the combination of intrinsic advantages of every *** work provides a reliable design of achieving the integration of thermal management functions into an aerogel composite and improves the thermal safety of lithium-ion batteries.

关键词： Thermal insulation