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2012年江浙沪儿科学术年会暨浙江省医学会儿科学分会学术年会、儿内科疾病诊治新进展国家级学习班

作者： li Di li xiao-zhong Department of Nephrology Children's Hospital Affiliated to Soochow University

Group A Streptococci (GAS) is gram-positive cocci which can be found in the nasopharynx and infections by GAS are one of the major causes of morbidity and mortality in children. Over recent years, despite of the apparent decline of severe GAS disease resulted from the prompt use of antibiotics, the total incidence rate of GAS infections has been increased. Infections caused by GAS include pharyngotonsillitis, community-acquired bronchopneumonia, pyoderma, cellulitis, osteomyelitis, rheumatic fever and poststreptococcal glomerulonephritis, as well as invasive diseases including necrotizing fasciitis, streptococcal toxic shock syndrome. Meanwhile,there are more and more reports about the relationship between dental caries, meningitis, pediatric autoimmune neuropsychiatric disorders and GAS infections. In the classification of GAS, sequence typing of the 5′ end of the M protein (emm) gene which is the molecular gold standard for typing GAS has gradually replaced classic M-protein serological typing, and there are currently more than 180 emm types described globally. The identification of opacity factor and the T protein are the new 'markers' for both phenotypic and molecular typing. At present, the management of GAS infections ranges from no treatment for benign conditions to prompt and aggressive antibiotic therapy and the consideration of adjunctive therapies for severe diseases especially life-threatening disease such as streptococcal toxic shock syndrome. Concerning the use of antibiotic of GAS infections, penicillin still is considered the first-line therapy. Erythromycin is the antibiotic of choice in the penicillin-allergic patient. However, the choice of antimicrobial therapy of GAS infections will be more complex with the emergence of resistance of GAS to macrolide antibiotics. Guidelines have been recommended for prevention and control of group A streptococcal infection in some countries. Nevertheless controversies exist in the dosages, courses and routes of

关键词： Group A Streptococci, infection, treatment, children

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A review of the research on music therapy in hospice care

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Frontiers of Nursing 2020年第3期7卷 179-183页

作者： Meng-Xue Fu Qin lin Ji-Jun Wu xiao-li zhong ling-Na Yang Guo-Jing Han Department of Nursing People's Hospital of Jianyang CityJianyangSichuan 641400China Department of Nursing Sichuan Nursing Vocational CollegeChengduSichuan 610100China Department of Nursing People’s Hospital of Deyang CityDeyangSichuan 618000China Department of Nursing Panzhihua UniversityPanzhihuaSichuan 617000China Department of Scientific Research Sichuan Nursing Vocational CollegeChengduSichuan 610100China Department of Pediatrics Sichuan Provincial Hospital for Women and ChildrenChengduSichuan 610041China

Objective:To summarize the research progress of music therapy in hospice care and to provide reference for further ***:A wide range of literatures on music therapy and hospice care at home and abroad were searched and read,and the literature was integrated,judged,analyzed,and ***:The related research on music therapy in hospice care mainly focused on western developed countries such as Europe and the United *** is still in the stage of theoretical exploration,lacking qualitative research based on case investigation and empirical research based on data ***:Music therapy supports the management of symptoms in hospice care,which can meet the diverse needs of patients and their family members including physical,psychological,social,and spiritual.

关键词： music therapy hospice care application and mechanism research progress review

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Early diagnosis and management of neonatal sepsis:a perspective

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World Journal of Pediatrics 2024年第4期20卷 303-306页

作者： li‑zhong Du Neonatal Intensive Care Unit Children’s Hospital Zhejiang University School of MedicineNational Clinical Research Center for Child Health3333 Binsheng RoadHangzhou 310052China

Neonatal sepsis is an illness caused by bloodstream bacteria or fungal infections that affect newborn infants under 28 days of *** stands as a significant contributor to morbidity and mortality in neonatal intensive care units(NICUs).With the improved survival rates of very low-birth-weight or extremely premature infants,a growing number of these vulnerable infants are receiving intensive care and undergoing invasive procedures,making nosocomial infections a persistent challenge in *** mortality rate associated with neonatal sepsis varies depending on factors such as birth weight,gestational age,and other *** can also lead to a range of long-term health consequences,including neurodevelopmental disabilities like cerebral palsy,visual or hearing impairments,and cognitive ***,neonatal sepsis is linked to various adverse outcomes,including respiratory complications,bronchopulmonary dysplasia,nutritional and growth issues,and immunological dysfunction[1].Due to its atypical clinical presentation and the low rate of specific diagnostic indicators,such as a positive blood culture,accurately diagnosing neonatal sepsis is ***,the appropriateness of antibiotic treatment is often a matter of controversy.

关键词： neonatal mortality diagnosis

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A Possible X-ray Quasi-periodic Oscillation in the Narrow-line Seyfert 1 Galaxy Mrk 142

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Research in Astronomy and Astrophysics 2024年第6期24卷 191-200页

作者： xiao-Gu zhong Jian-Cheng Wang Yong-Yun Chen xiao-ling Yu College of Physics and Electronic Engineering Qujing Normal UniversityQujing 655011China Yunnan Observatories Chinese Academy of SciencesKunming 650216China

A possible quasi-periodic oscillation(QPO) at frequency 7.045 × 10^(-5) Hz is found in the narrow-line Seyfert 1galaxy Mrk 142 in the data of XMM-Newton collected on 2020 April *** find that the QPO signal is statistically significantly larger than the 5σ level and highly coherent with quality factor Q > 5 at the 0.3–10 keV band by using the method of the Lomb–Scargle Periodogram,the Weighted Wavelet Z-transform and the *** analyze the data in 0.3–0.6 keV,0.6–1 keV,1–3 keV and 3–10 keV energy bands,and find obvious QPO signals at 0.3–0.6 keV and 1–3 keV *** then analyze the time-average spectra and time variability at the QPO frequency of 7.045 × 10^(-5) Hz,and use a model to fit *** find that the QPO signal mainly comes from the X-ray hot corona.

关键词： X-rays:galaxies galaxies:Seyfert accretion accretion disks radiation mechanisms:general

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An intrinsically self-healing and anti-freezing molecular chains induced polyacrylamide-based hydrogel electrolytes for zinc manganese dioxide batteries

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Journal of Energy Chemistry 2024年第2期89卷 565-578,I0013页

作者： Haiyang liao Wenzhao zhong Chen li Jieling Han xiao Sun Xinhui Xia Ting li Abolhassan Noori Mir F.Mousavi Xin liu Yongqi Zhang Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 611731SichuanChina School of Mechanical Engineering Hunan University of TechnologyZhuzhou 412007HunanChina School of Materials Science and Engineering Zhejiang University of TechnologyHangzhou 310014ZhejiangChina Department of Chemistry Faculty of Basic SciencesTarbiat Modares UniversityTehran 14117-13116Iran State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200HubeiChina

The anti-freezing strategy of hydrogels and their self-healing structure are often contradictory,it is vital to break through the molecular structure to design and construct hydrogels with intrinsic anti-freezing/self-healing for meeting the rapid development of flexible and wearable devices in diverse service ***,we design a new hydrogel electrolyte(AF/SH-Hydrogel)with intrinsic anti-freezing/self-healing capabilities by introducing ethylene glycol molecules,dynamic chemical bonding(disulfide bond),and supramolecular interaction(multi-hydrogen bond)into the polyacrylamide molecular *** to the exceptional freeze resistance(84%capacity retention at-20℃)and intrinsic self-healing capabilities(95%capacity retention after 5 cutting/self-healing cycles),the obtained AF/SH-Hydrogel makes the zinc||manganese dioxide cell an economically feasible battery for the state-of-the-art *** Zn||AF/SH-Hydrogel||MnO_(2)device offers a near-theoretical specific capacity of 285 m A h g^(-1)at 0.1 A g^(-1)(Coulombic efficiency≈100%),as well as good self-healing capability and mechanical flexibility in an ice *** work provides insight that can be utilized to develop multifunctional hydrogel electrolytes for application in next generation of self-healable and freeze-resistance smart aqueous energy storage devices.

关键词： Flexible aqueous battery Hydrogel electrolyte Anti-freezing Self-healing Dual-dynamic reversible bond

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数字经济发展与企业价值提升——基于生命周期理论的视角

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经济问题 2021年第3期 116-121页

作者：李小忠太原市热力集团有限公司山西太原030006

有效地发挥数字经济的作用,引导和帮助企业进行数字化转型,对促进企业价值提升,进而驱动经济高质量发展有重要意义。以我国2011—2019年A股上市公司为研究样本,采用双重差分模型实证检验数字经济对企业价值的影响以及企业生命周期不同... 详细信息

有效地发挥数字经济的作用,引导和帮助企业进行数字化转型,对促进企业价值提升,进而驱动经济高质量发展有重要意义。以我国2011—2019年A股上市公司为研究样本,采用双重差分模型实证检验数字经济对企业价值的影响以及企业生命周期不同阶段数字经济对企业价值影响关系的差异。研究发现,数字经济发展有利于促进企业价值提升。对不同生命周期阶段的企业而言,数字经济发展对企业价值的影响效应差异明显,处于成熟期的企业,数字经济发展对企业价值提升具有显著的促进作用;而处于初创期和成长期的企业,数字经济发展对企业价值提升没有显著影响。进一步发现,数字经济发展能促进国有企业价值提升,也能促进非国有企业价值提升,但对非国有企业的影响更加显著,这种效应主要体现在成熟期企业之中,而对初创期和成长期企业的影响不显著。

关键词：数字经济企业价值生命周期产权性质

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Comprehensive Bile Acid Profiling of ABCB4-mutated Patients and the Prognostic Role of Taurine-conjugated􀀖􀄮􀀏􀀙􀄮􀀏􀀚􀄮􀀏􀀔􀀕􀄮􀀐􀀷􀁈􀁗􀁕􀁄􀁋􀁜􀁇􀁕􀁒􀁛􀁜􀁏􀁄􀁗􀁈􀁇􀀃􀀥􀁌􀁏􀁈􀀃􀀤􀁆􀁌􀁇􀀃􀁌􀁑􀀃􀀦􀁋􀁒􀁏􀁈􀁖􀁗􀁄􀁖􀁌􀁖

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Journal of Clinical and Translational Hepatology 2024年第2期12卷 151-161页

作者： Teng liu Ren-Xue Wang Jun Han zhong-Die li Jonathan ASheps li-Juan Zheng xiao-xiao Xu Victor ling Jian-She Wang Department of Pediatrics Shanghai Medical CollegeFudan UniversityThe Center for Pediatric Liver DiseasesChildren’s Hospital of Fudan UniversityShanghaiChina BC Cancer Agency VancouverBritish Columbia V5Z 1L3Canada University of Victoria-Genome BC Proteomics Center University of VictoriaVictoriaBritish Columbia V8Z 7X8Canada Shanghai Key Laboratory of Birth Defect ShanghaiChina

Background and Aims:We asked if comprehensive bile acid profiling could provide insights into the physiopathology of ABCB4-mutated patients and evaluated the prognostic value of taurine-conjugated tetrahydroxylated bile acid(tauro-THBA)in ***:Serum bile acid profiles were evaluated in 13 ABCB4-mutated patients with 65 healthy controls by ultra-high-performance liquid chromatography/multiple-reaction monitoring-mass spectrometry(UPLC/MRM-MS).The concentration of tauro-THBA was compared between ABCB4-mutated patients with different *** areas under the curve(AUCs)of tauro-THBA were compared between ABCB11-mutated patients with native liver survival and those who died or underwent liver transplantation before 3 years of age by receiver operating characteristic curve(ROC),with another patient cohort for further ***:The overall hydrophobicity indices of bile acids in ABCB4-mutated patients(12.99±3.25 m)were significantly lower than those of healthy controls(14.02±1.74 m,plinical outcome in low gammaglutamyl transferase intrahepatic cholestasis patients.

关键词： Bile acids MDR3 BSEP PFIC liquid chromatography-mass spectrometry

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Root cause of corrosion failure of tin coating on wire clamp in marine atmosphere

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Journal of Iron and Steel Research International 2024年第4期31卷 998-1014页

作者： Zhen zhong Wang-yan Ly Teng-yuan liu Yi Xie Yang Yang Zhen-zhu Wang Deng-ke li xiao-bo li Tang-qing Wu School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105HunanChina Electric Power Research Institute of Guangdong Power Grid Co. Ltd.Guangzhou 510080GuangdongChina Shenyang National L aboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina School of Materials Science and Engineering.University of Science and Technology of China Shenyang 110016LiaoningChina Electric Power Research Institute State Grid Hunan Electric Power CompanyChangsha 410007HunanChina School of Mechanical Engineering and Mechanics Xiangtan UniversityXiangtan 411105HunanChina School of Information Science and Engineering Changsha Normal UniversityChangsha 410199HunanChina

The failure cause of a tinned copper wire clamp in marine atmosphere was studied systematically by X-ray photoelectron spectroscopy,scanning electron microscopy with energy dispersive spectroscopy and electrochemical *** main components of the green rust on the surface of the damaged wire clamp are SnO_(2),CuO,Cu_(2)Cl(OH)_(3) and CuCO(OH)_(2).Much of green rust distributes at the platform edge along the axial direction on the crimp connection,and severe corrosion and corrosion pits occur at the platform edge zone along the axial *** enriching Cl-at the marine atmosphere and the existing O_(2) in air collectively enhance the corrosion process of the tin coating and the copper *** element model results show that the residual stress and strain of the tin coating are the largest at the platform edge along the axial direction on the crimp connection,and the corresponding electrode potential of the tin coating at this zone drops *** above results indicate that the residual strain increases the driving force of the corrosion electrochemical reactions and accelerates the corrosion rate and the pit corrosion of the tin coating at this zone.

关键词： Tin coating Marine atmosphere Residual strain-Chloride ion Corrosion failure

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Thermally modulated photoelectronic synaptic behavior in HfS_(2)/VO_(2) heterostructure

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Rare Metals 2024年第8期43卷 3798-3809页

作者： Le Wang lin Wang xiao-Yun Ye Xiong-Hu Xu li-Yan Shang Ya-Wei li Jin-zhong Zhang liang-Qing Zhu Zhi-Gao Hu Technical Center for Multifunctional Magneto-Optical Spectroscopy(Shanghai) Engineering Research Center of Nanophotonics&Advanced Instrument(Ministry of Education)Department of PhysicsSchool of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

Neuromorphic computing is known for its efficient computational speed,low latency,and reduced power consumption,which is considered a pivotal technology to overcome the von Neumann *** synapses are an indispensable component of neuromorphic computational artificial neural *** guarantee effective and precise processing of optical signals,it must have a high responsivity,detectivity,and the ability to adapt to various ***,a synaptic transistor based on the HfS_(2)/VO_(2) heterojunction with a responsivity of8.6×10^(3) A·W^(-1)and a detectivity of 1.26×10^(14)Jones at405 nm laser was ***,the typical synaptic behavior was successfully simulated,including postsynaptic currents(PSCs),the transition from shortterm plasticity(STP)to long-term plasticity(LTP).When VO_(2) converts from the semiconductor state to the metal state,the HfS_(2)/VO_(2) heterojunction transforms into a Schottky heterojunction from a TypeⅡheterojunction with ***'s important,the heterojunction still exhibits excellent responsivity and detectivity,as well as stability of synaptic *** addition,the classical Pavlovian conditioning experiment is simulated under different laser intensity to study the brain's associative learning *** results demonstrate that the HfS_(2)/VO_(2) heterojunction synapse exhibits significant responsivity and detectivity and is adaptable to high-temperature environments,showing great potential for neuromorphic computational applic ations.

关键词： HfS_(2) VO_(2) Phase transition Photoelectric synapse Heterojunction

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关于青年学生创造力培养的几个心理学问题

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东北师大学报（哲学社会科学版） 2000年第4期 77-83页

作者：李孝忠东北师范大学教育科学学院吉林长春130024

考查近七八十年心理学的相关研究 ,使我们看到 ,创造力是人才结构中最重要的因素。而培养青年学生的创造力 ,就必须了解创造能力及其结构。创造力是产生新颖而有价值成果的能力 ,它由创造性个性和发散思维等成分构成。笔者还构建了培养... 详细信息

考查近七八十年心理学的相关研究 ,使我们看到 ,创造力是人才结构中最重要的因素。而培养青年学生的创造力 ,就必须了解创造能力及其结构。创造力是产生新颖而有价值成果的能力 ,它由创造性个性和发散思维等成分构成。笔者还构建了培养青年学生创造力的模式 ,即创设障碍 ,激发奋斗 ,引导发散 ,体验灵感 ;主张用综合指标编制创造力测验。

关键词：青年学生创造力培养创造性个性发散思维

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