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Galvanic Corrosion Behavior of Copper-Drawn Steel for Grounding Grids in the Acidic Red Soil Simulated Solution

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Acta Metallurgica Sinica(English Letters) 2020年第11期33卷 1571-1582页

作者： xiao-lei fan Yun-Xiang Chen Jun-Xi Zhang De-Yuan Lin Xuan-Xuan Liu xiao-Jian Xia Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power Shanghai University of Electric PowerShanghai 200090China Electric Power Research Institute of State Grid Fujian Electric Power Company Limited Fuzhou 350007China

The influence of pH and metallographic structure on the corrosion behavior of copper-drawn steel is studied with the simulated *** effect of pH on the corrosion behavior of copper-drawn steel has been investigated using open-circuit potential,potentiodynamic polarization,galvanic current measurement,scanning electron microscopy and scanning vibrating electrode technique *** steel is corroded as anode,while the corrosion of copper plate is protected as *** the results revealed that pH and metallographic structure had a significant influence on the corrosion behavior of copper-drawn *** the decrease in pH value from 6 to 2.4,the corrosion rate of copper-drawn steel galvanic couple(Cu-Fe GC)obviously increased in the simulated solution of acidic red *** electric field formed by the Cu-Fe GC changes the direction of ion migration between the copper and drawn steel electrodes,which impacts the composition and microstructure of corrosion products formed on the electrode surface.

关键词： Cu-Fe galvanic couple Electrochemical test Scanning vibrating electrode technique(SVET)measurement Soil corrosion

Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin xiao fangqing Zhao Jing-Dong J.Han Qi Liu xiaohui fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

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SCADA系统在长输原油管道上的应用

自动化与仪表 2012年第5期27卷 42-45页

作者：雷小凡李睿王秀全中石化管道储运分公司洪荆输油处荆门448000

以洪荆、钟荆原油管道SCADA系统为例,阐述了该系统的架构、通讯设计、SCADA系统功能等。长输原油管道采用密闭输送工艺,其自动控制系统为SCADA系统,实现在调度中心对全线进行监控、调度和管理,沿线各个工艺站场达到无人操作,有人值守。... 详细信息

以洪荆、钟荆原油管道SCADA系统为例,阐述了该系统的架构、通讯设计、SCADA系统功能等。长输原油管道采用密闭输送工艺,其自动控制系统为SCADA系统,实现在调度中心对全线进行监控、调度和管理,沿线各个工艺站场达到无人操作,有人值守。介绍了洪荆、钟荆原油管线的工艺流程和主要设备,并详细描述了SCADA系统的硬件、软件配置,以及所实现的功能。

关键词：输油管道数据采集与监控系统配置系统功能

Effects of carbon content on the microstructure and tensile properties of a low-density steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 391-401页

作者： Yongxuan Shang Mingyu fan Shuyong Jiang Zhongwu Zhang Key Laboratory of Superlight Materials and Surface Technology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China State Key Laboratory of Metal Material for Marine Equipment and Application Iron&Steel Research Institute of Ansteel Group CorporationAnshan 114009China

Carbon can change the phase components of low-density steels and influence the mechanical *** this study,a new method to control the carbon content and avoid the formation ofδ-ferrite by decarburization treatment was *** microstructural changes and mechanical characteristics with carbon content induced by decarburization were systematically ***-Jaoul(C-J)analysis was employed to examine the work hardening characteristics during the tensile *** decarburization by heat treatments,the carbon content within the austenite phase decreased,while Mn and Al were almost unchanged;this made the steel with full austenite transform into the austenite and ferrite dual ***,(Ti,V)C carbides existed in both matrix phase and the mole fraction almost the *** addition,the formation of other carbides *** loss induced a decrease in strength due to the weakening of the carbon solid *** the steel with the single austinite,the deformation mode of austenite was the dislocation planar glide,resulting in the formation of *** the dual-phase steel,the deformation occurred by the dislocation planar glide of austenite first,with the increase in strain,the cross slip of ferrite took place,forming dislocation cells in *** the late stage of deformation,the work hardening of austinite increased rapidly,while that of ferrite increased slightly.

关键词： low-density steels carbon content decarburization strengthening mechanisms work hardening behavior

THE ANTAGONISM OF ANGIOTENSIN Ⅱ ON THE DEPRESSOR EFFECT OF CLONIDINE IN RAT SPINAL CORD

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Chinese Science Bulletin 1989年第8期34卷 688-692页

作者：徐晓军范镭于英心韩济生 Department of Physiology Beijing Medical University

There is a large body of evidence to suggest existence of endogenous anti-opioid substances (AOS) in central nervous system to antagonize the actions of endogenous opioid peptides. Angiotensin Ⅱ has been considered as one of the AOS because it was found to antagonize opioid activity in various physiological and pharmacological systems. In present work, we studied the antagonistic effect of angiotensin Ⅱ on the cardiovascular activities of endogenous opioids.

关键词： clonidine angiotensin Ⅱ anti-opioid substane.

Soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias

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Neural Regeneration Research 2025年第9期20卷 2585-2586页

作者： Andrew Gregory Chengyun Tang fan fan Department of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global *** the World Health Organization,AD/ADRD has affected more than 55 million individuals worldwide,with an additional 10 million cases diagnosed each year.

关键词： Alzheimer population drug

Tackling the microlensing wave effects of strong lensing gravitational waves with TAAH

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 257-258页

作者： Zuhui fan South-Western Institute for Astronomy Research Yunnan University

The rapid development of gravitational wave（GW） observations since their first detection in 2015 [1] has opened a completely new window for exploring the Universe. Consequently, astronomical research has entered the multimessenger era, allowing us to use different tracers to view the cosmos from various perspectives. Among others, the appealing application of gravitational wave events from compact binary mergers is that they can act as standard sirens to determine absolute cosmic distances entirely independent of standard candles. This approach is one of the most promising means to solve the current H0tension problem.

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Three‑Dimensional Numerical Study on the Metal Rotating Spray Transfer Process of High‑Current GMAW

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Chinese Journal of Mechanical Engineering 2022年第6期35卷 234-246页

作者： lei xiao Ding fan Jiankang Huang School of Materials Science and Engineering Lanzhou Jiaotong UniversityLanzhou 730070China State Key Laboratory of Advanced Processing and Recycling of Non‑ferrous Metals Lanzhou University of TechnologyLanzhou 730050China School of Materials Science and Engineering Lanzhou University of TechnologyLanzhou 730050China

A three-dimensional numerical model based on the volume-of-fluid(VOF)method is typically preferred for studying high-current gas metal arc welding(GMAW)metal transfer mechanism and then controlling *** is informed that the rotating spray transfer is extremely complicated,and some researchers have focused on simplified models without considering the energy conservation to make analysis manageable for the unstable metal transfer *** our created numerical model,the metal transfer of high-current GMAW with shielding gas of different conductivities has been studied by analyzing acting forces and fluid flows in the metal liquid column,especially for the contributions of the self-induced electromagnetic force,equivalent volume force of the capillary pressure of the surface tension(Named surface tension force in this work),static arc *** is found that the unbalanced electromagnetic force greatly promotes the metal rotating motion in 500 A metal inert gas(MIG)welding with pure argon shielding gas and it pushes the metal liquid column to *** the arc constricting effect in active shielding gas by simply changing the arc conductivity,it is found that the metal liquid column no longer rotates,it turns to swing since the unbalanced electromagnetic force is large enough to break the rotating *** calculated results of the metal liquid column deflected angle and rotating/swing frequency agree well with the experiment of high-speed camera observations.

关键词： Gas metal arc welding Rotating spray transfer Three-dimensional model Electromagnetic force Surface tension

Zwitterionic hyaluronic acid derivatives for co-delivery of both chemotherapeutic and nucleic acid drugs in breast cancer treatment

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Nano Research 2025年第1期18卷 607-617页

作者： Ruo-Lin Jiang Hui-Na Liu Yu-fan Yang Zhi-Cheng Zhang Qi Dai xiao-Yan Bao Lin-Jie Wu Ya-Xin Qin Xin Tan xiao-Yan Sun Xu-fang Ying Zhi-Qing Ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin