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A low prevalence of H pylori and endoscopic findings in HIV-positive Chinese patients with gastrointestinal symptoms

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World Journal of Gastroenterology 2007年第41期13卷 5492-5496页

作者： fu-Jing Lv xiao-lan Luo Xin Meng Rui Jin Hui-Guo Ding Shu-Tian Zhang Department of Digestive Diseases Beijing You'an Hospital Capital Medical University Beijing 100069 China Pathology Department Beijing You'an Hospital Capital Medical University Beijing 100069 China Department of Digestive Diseases Beijing Friendship Hospital Capital Medical University Beijing 100050 China

AIM： To compare the prevalence of H pylori infection, peptic ulcer, cytomegalovirus （CNV） infection and Candida esophagitis in human immunodeficiency virus （HIV）- positive and HIV-negative patients, and evaluate the impact of CD4 lymphocyte on H pylori and opportunistic infections. METHODS： A total of 151 patients （122 HIV-positive and 29 HIV-negative） with gastrointestinal symptoms were examined by upper endoscopy and biopsy. Samples were assessed to determine the prevalence of Hpylori infection, CMV, candida esophagitis and histologic chronic gastritis. RESULTS： The prevalence of Hpylori was less common in HIV-positive patients （22.1%） than in HIV-negative controls （44.8%; P 〈 0.05）, and the prevalence of H pylori displayed a direct correlation with CD4 count stratification in HIV-positive patients. In comparison with HIV-negative group, HIV-positive patients had a lower incidence of peptic ulcer （20.7% vs 4.1%; P 〈 0.01）, but a higher prevalence of chronic atrophy gastritis （6.9% vs 24.6%; P 〈 0.05）, Candida esophagitis and CMV infection. Unlike HIV-negative group, H pylori infection had a close relationship to chronic active gastritis （P 〈 0.05）. In HIV-positive patients, chronic active gastritis was not significantly different between those with Hpylori infection and those without. CONCLUSION： The lower prevalence of H pylori infection and peptic ulcer in HIV-positive patients with gastrointestinal symptoms suggests a different mechanism of peptic ulcerogenesis and a different role of H pylori infection in chronic active gastritis and peptic ulcer. The pathogen of chronic active gastritis in HIV-positive patients may be different from the general population that is closely related to Hpylori infection.

关键词： Human immunodeficiency virus Endoscopy Cytomegalovirus Candida esophagitis H pylori Peptic ulcer Chronic gastritis

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Aerobic exercise suppresses hepatocellular carcinoma by downregulating dynamin-related protein 1 through PI3K/AKT pathway

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Journal of Integrative Medicine 2021年第5期19卷 418-427页

作者： Tong Zhao Bing-jie Guo Chu-lan xiao Jiao-jiao Chen Can Lü Fan-fu Fang Bai Li School of Traditional Chinese Medicine Naval Medical UniversityShanghai 200433China Nanjing University of Chinese Medicine.Nanjing 210023 Jiangsu ProvinceChina

Objective: Exercise, as a common non-drug intervention, is one of several lifestyle choices known to reduce the risk of cancer. Mitochondrial division has been reported to play a key role in the occurrence and transformation of hepatocellular carcinoma(HCC). This study investigated whether exercise could regulate the occurrence and development of HCC through ***: Bioinformatics technology was used to analyze the expression level of dynamin-related protein1(DRP1), a key protein of mitochondrial division. The effects of DRP1 and DRP1 inhibitor(mdivi-1) on the proliferation and migration of liver cancer cells BEL-7402 were observed using cell counting kit-8, plate colony formation, transwell cell migration, and scratch experiments. Enzyme-linked immunosorbent assay, Western blot and real-time polymerase chain reaction were used to detect the expression of DRP1 and its downstream phosphoinositide 3-kinase(PI3 K)/protein kinase B(AKT) pathway. A treadmill exercise intervention was tested in a nude mouse human liver cancer subcutaneous tumor model expressing different levels of DRP1. The size and weight of subcutaneous tumors in mice were detected before and after ***: The expression of DRP1 in liver cancer tissues was significantly upregulated compared with normal liver tissues(P<0.001). The proliferation rate and the migration of BEL-7402 cells in the DRP1 overexpression group were higher than that in the control group. The mdivi-1 group showed an inhibitory effect on the proliferation and migration of BEL-7402 cells at 50 lmol/L. Aerobic exercise was able to inhibit the expression of DRP1 and decrease the size and weight of subcutaneous tumors. Moreover,the expression of phosphorylated PI3 K(p-PI3 K) and phosphorylated AKT(p-AKT) decreased in the exercise group. However, exercise could not change p-PI3 K and p-AKT levels after knocking down DRP1 or using mdivi-1 on subcutaneous ***: Aerobic exercise can suppress the development of

关键词： Aerobic exercise Hepatocellular carcinoma Dynamin-related protein PI3K/AKT pathway

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Remote Sensing Image Registration Based on Improved KAZE and BRIEF Descriptor

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International Journal of Automation and computing 2020年第4期17卷 588-598页

作者： Huan Liu Gen-fu xiao College of Electronic and Information Engineering Jinggangshan University&Jiangxi Engineering Laboratory of Internet of Things(IoT)Technologies for Crop GrowthJi'an 343009China College of Mechanical and Electronic Jinggangshan UniversityJi'an 343009China

Remote sensing image registration is still a challenging task owing to the significant influence of nonlinear differences between remote sensing *** solve this problem,this paper proposes a novel approach with regard to feature-based remote sensing image *** are two key contributions:1)we bring forward an improved strategy of composite nonlinear diffusion filtering according to the scale factors in multi-scale space and 2)we design a gradually decreasing resolution of multi-scale pyramid *** a binary code string is served as feature descriptors to improve matching *** experiments of different categories of remote image datasets on feature extraction and feature registration are *** experimental results demonstrate the superiority of our proposed scheme compared with other classical algorithms in terms of correct matching ratio,accuracy and computation efficiency.

关键词： Remote sensing image image registration composite nonlinear diffusion filter binary code string multi-scale pyramid space

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High order symplectic conservative perturbation method for time-varying Hamiltonian system

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Acta Mechanica Sinica 2012年第3期28卷 885-890页

作者： Ming-Hui fu Ke-lang Lu Lin-Hua lan Department of Applied Mechanics and Engineering Sun Yat-sen University510275 GuangzhouChina

This paper presents a high order symplectic con- servative perturbation method for linear time-varying Hamil- tonian system. Firstly, the dynamic equation of Hamilto- nian system is gradually changed into a high order pertur- bation equation, which is solved approximately by resolv- ing the Hamiltonian coefficient matrix into a ＂major compo- nent＂ and a ＂high order small quantity＂ and using perturba- tion transformation technique, then the solution to the orig- inal equation of Hamiltonian system is determined through a series of inverse transform. Because the transfer matrix determined by the method in this paper is the product of a series of exponential matrixes, the transfer matrix is a sym- plectic matrix; furthermore, the exponential matrices can be calculated accurately by the precise time integration method, so the method presented in this paper has fine accuracy, ef- ficiency and stability. The examples show that the proposed method can also give good results even though a large time step is selected, and with the increase of the perturbation or- der, the perturbation solutions tend to exact solutions rapidly.

关键词： Time-varying Hamiltonian system High ordermultiplicative perturbation Symplectic conservation expo-nential matrix Precise time integration method

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Fabrication and properties of Al matrix composites strengthened by in situ alumina particulates

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Journal of University of Science and Technology Beijing 2006年第3期13卷 263-266页

作者： Gaofeng fu lan Jiang Ji Liu Yue Wang School of Materials and Metallurgy Northeastern University Shenyang 110004 China

New aluminum matrix composites strengthened by Al2O3 particulates through stirring cast by adding NH4Al（SO4）2 to the molten aluminum have been fabricated. TEM observation shows that in-situ Al2O3 particulates are generally spherical and they are uniformly distributed in the Al matrix. Dry sliding wear test results show that the volume loss of the unreinforced Al matrix is about three times that of the Al2O3 reinforced metal matrix composite （MMC） and the volume loss of the MMC fabricated by adding Al2O3 is larger than that of the MMC by adding NH4Al（SO4）2. Lubricating sliding wear test results show that the volume loss of the MMCs increases more slowly than that of the matrix with the increasing of the load.

关键词： aluminum matrix composite alumina microstructure wear

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辽朝详稳渊源新论

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古代文明（中英文） 2025年第1期19卷 117-127,M0006,M0007页

作者：田富吉林大学历史文化学院吉林长春130012

以往学界多认为辽朝详稳源于突厥语“sangun”,为将军之意。本文通过考证详稳与相温、相公、将军等概念的异同,认为辽朝详稳一词源自汉语“相”,“稳”是指契丹语语法中修饰“详”字的附加成分。辽朝详稳官职来源于突厥、回鹘、吐蕃等... 详细信息

以往学界多认为辽朝详稳源于突厥语“sangun”,为将军之意。本文通过考证详稳与相温、相公、将军等概念的异同,认为辽朝详稳一词源自汉语“相”,“稳”是指契丹语语法中修饰“详”字的附加成分。辽朝详稳官职来源于突厥、回鹘、吐蕃等边疆民族之“相”制,又在“会同改制”过程中脱离其原义,遂成为一种特殊的部族官职。

关键词：辽朝详稳相相温国相

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Heteroscedastic regression analysis method for mixed data

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航空动力学报 2011年第4期26卷 721-726页

作者： fu Hui-min YUE xiao-rui Research Center of Small Sample Technology Beijing University of Aeronautics and Astronautics Beijing 100191 China

The heteroscedastic regression model was established and the heteroscedastic regression analysis method was presented for mixed data composed of complete data,type-Ⅰ censored data and type-Ⅱ censored data from the location-scale *** best unbiased estimations of regression coefficients,as well as the confidence limits of the location parameter and scale parameter were ***,the point estimations and confidence limits of percentiles were ***,the traditional multiple regression analysis method which is only suitable to the complete data from normal distribution can be extended to the cases of heteroscedastic mixed data and the location-scale *** the presented method has a broad range of promising applications.

关键词： heteroscedastic regression analysis censored data performance test life prediction reliability analysis

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Combustion instability of pilot flame in a pilot bluff body stabilized combustor

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Chinese Journal of Aeronautics 2015年第6期28卷 1606-1615页

作者： fu xiao Yang fujiang Guo Zhihui National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics School of Energy and Power Engineering Beihang University

Combustion instability of pilot flame has been investigated in a model pilot bluff body stabilized combustor by running the pilot flame only. The primary objectives are to investigate the pilot flame dynamics and to provide bases for the study of the interaction mechanisms between the pilot flame and the main flame. Dynamic pressures are measured by dynamic pressure transduc- ers. A high speed camera with CH＊ bandpass filter is used to capture the pilot flame dynamics. The proper orthogonal decomposition （POD） is used to further analyze the high speed images. With the increase of the pilot fuel mass flow rate, the pilot flame changes from stable to unstable state grad- ually. The combustion instability frequency is 136 Hz when the pilot flame is unstable. Numerical simulation results show that the equivalence ratios in both the shear layer and the recirculation zone increase as the pilot fuel mass flow rate increases. The mechanism of the instability of the pilot flame can be attributed to the coupling between the second order acoustic mode and the unsteady heat release due to symmetric vortex shedding. These results illustrate that the pilot fuel mass flow rate has significant influences on the dynamic stability of the pilot flame.

关键词： Combustion instability High speed image Pilot flame Proper orthogonal decom-position (POD) Vortex shedding

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Malicious code passive propagation model and vaccine distribution model of P2P networks

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Journal of Systems Engineering and Electronics 2010年第1期21卷 161-167页

作者： xiaolong Xu Ruchuan Wang fu xiao School of Computer Nanjing University of Posts and Telecommunications Nanjing 210003 E R. China State Key Laboratory for Novel Software Technology Nanjing University Nanjing 210093 P. R. China

To fight against malicious codes of P2P networks, it is necessary to study the malicious code propagation model of P2P networks in depth. The epidemic of malicious code threatening P2P systems can be divided into the active and passive propagation models and a new passive propagation model of malicious code is proposed, which differentiates peers into 4 kinds of state and fits better for actual P2P networks. From the propagation model of malicious code, it is easy to find that quickly making peers get their patched and upgraded anti-virus system is the key way of immunization and damage control. To distribute patches and immune modules efficiently, a new exponential tree plus （ET＋） and vaccine distribution algorithm based on ET＋ are also proposed. The performance analysis and test results show that the vaccine distribution algorithm based on ET＋ is robust, efficient and much more suitable for P2P networks.

关键词： data security and computer security computer virus,peer-to-peer computing propagation immune exponential tree.

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Research on new type of fast-opening mechanism in steam turbine regulating system and optimization of operation tactic

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第5期9卷 633-639页

作者： xiao-xiao LI Xuan-yin WANG fu-shang LI The State Key Laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China Shandong Electrical Power Institute Jinan 250002 China

With the analysis on regulating system in 200 MW steam turbine, the necessity of appending the fast-opening function to the original system is set forth and a new type of fast-opening mechanism is devised. The mathematical model of system is built up. With the use of AMESIM software, the displacement curve of the piston, the force curve of the cartridge valve spool, the pressure curve and the flux curve in the regulation process are obtained based on simulation. The performances of three fast-opening systems composed of cartridge valves with different diameters are compared. Based on the analysis on factors that affect the execution time of fast-opening, the dead zone of the fast-opening system is put forward. To overcome the defect, dif- ferent operation modes are adopted for different zones. The result shows that with the increase of the valve diameter, the regulating time in the dead zone significantly exceeds the fast-opening time in the whole journey. Accordingly, the optimization operation tactic in the dead zone and the qualification conditions are brought forward. The fast-opening system composed of 32 mm cartridge valves is taken as an example with use of the tactic. The simulation result shows that the maximum regulating time is shortened by 509 ms.

关键词： Steam turbine Fast-opening Regulating system AMESIM

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