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Holographic technicolor model and dark matter

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Chinese Physics C 2020年第9期44卷 16-24页

作者： Yidian Chen xiao-jun bi Mei Huang Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China School of Physics University of Chinese Academy of SciencesBeijing 100049China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

We investigate the strongly coupled minimal walking technicolor model(MWT)in the framework of a bottom-up holographic model,where the global SU(4)symmetry breaks into SO(4)*** the holographic model,we found that 125 GeV composite Higgs particles and small Peskin–Takeuchi S parameter can be achieved *** addition,the model predicts a large number of particles at the TeV scale,including dark matter candidates Technicolor Interacting Massive Particles(TIMPs).If we consider the dark matter nuclear spin-independent cross-section in the range of 10^−45∼10^−48cm^2,which can be detected by future experiments,the mass range of TIMPs predicted by the holographic technicolor model is 2∼4 TeV.

关键词： dark matter holography technicolor

Feedback of Efficient Shock Acceleration on Magnetic-field Structure Inside Young Type Ia Supernova Remnants

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Research in Astronomy and Astrophysics 2024年第6期24卷 234-244页

作者： jun-Yu Shen bi-Wen Bao Li Zhang Department of Astronomy Key Laboratory of Astroparticle Physics of Yunnan ProvinceYunnan UniversityKunming 650091China Key Laboratory of Statistical Modeling and Data Analysis of Yunnan Province Yunnan UniversityKunming 650091China

Using an effective adiabatic index γ_(eff) to mimic the feedback of efficient shock acceleration,we simulate the temporal evolution of a young type Ia supernova remnant (SNR) with two different background magnetic field(BMF) topologies:a uniform and a turbulent *** density distribution and magnetic-field characteristics of our benchmark SNR are studied with two-dimensional cylindrical magnetohydrodynamic *** γ_(eff)is considered,we find that:(1) the two-shock structure shrinks and the downstream magnetic-field orientation is dominated by the Rayleigh–Taylor instability structures;(2) there exists more quasi-radial magnetic fields inside the shocked region;and (3) inside the intershock region,both the quasi-radial magnetic energy density and the total magnetic energy density are enhanced:in the radial direction,with γ_(eff)=1.1,they are amplified about 10–26 times more than those with γ_(eff)=5/*** in the angular direction,the total magnetic energy densities could be amplified about 350 times more than those with γ_(eff)=5/3,and there are more grid cells within the intershock region where the magnetic energy density is amplified by a factor greater than 100.

关键词： methods:numerical ISM:magnetic fields ISM:supernova remnants magnetohydrodynamics(MHD)

Recent Advances in Deciphering the Mechanisms and biological Functions of DNA Demethylation

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Chinese Journal of Chemistry 2024年第6期42卷 645-651页

作者： Yang Feng Sheng-jun Chen bi-Feng Yuan Key Laboratory of Aquatic Product Processing Ministry of Agriculture and Rural AffairsNational R&D Center for Aquatic Product ProcessingSouth China Sea Fisheries Research InstituteChinese Academy of Fishery SciencesGuangzhouGuangdong510300 China School of Public Health Research Center of Public HealthRenmin Hospital of Wuhan UniversityWuhan UniversityWuhanHubei430071 China

5-Methylcytosine (5mC) is a dynamic and reversible epigenetic modification in genomic DNA of higher *** has been well-established that the demethylation of 5mC occurs through the ten-eleven translocation (TET)-mediated oxidation of 5mC followed by thymine DNA glycosylase (TDG)-initiated base excision repair (BER).Recent findings also have identified an alternative pathway of DNA *** this pathway,TET enzymes directly oxidize 5mC to form 5-formylcytosine (5fC) or 5-carboxylcytosine (5caC).These modified bases can undergo direct deformylation or decarboxylation,***,DNA demethylation can also occur through the deamination of 5mC and 5hmC,resulting in the production of thymine and 5-hydroxymethyluracil (5hmU),*** DNA demethylation pathways possess critical functional implications and roles in biological *** Recent Advances article will focus on the studies of mechanisms and biological functions of DNA demethylation,shedding light on the reversible nature of the epigenetic modification of 5mC.

关键词： Epigenetics DNA DNA methylation 5-Methylcytosine Demethylation Mechanisms biological functions C—C bond cleavage Mass spectrometry

bioinspired nanomaterials for wearable sensing and human–machine interfacing

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Nano Research 2024年第2期17卷 445-461页

作者： Vishesh Kashyap junyi Yin xiao xiao jun Chen Department of bioengineering University of CaliforniaLos AngelesLos AngelesCA 90095USA Department of Mechanical and Aerospace Engineering University of CaliforniaLos AngelesLos AngelesCA 90095USA

The inculcation of bioinspiration in sensing and human–machine interface(HMI)technologies can lead to distinctive characteristics such as conformability,low power consumption,high sensitivity,and unique properties like self-healing,self-cleaning,and *** sensing and HMI are fields rife with opportunities for the application of bioinspired nanomaterials,particularly when it comes to wearable sensory systems where biocompatibility is an additional *** review discusses recent development in bioinspired nanomaterials for wearable sensing and HMIs,with a specific focus on state-of-the-art bioinspired capacitive sensors,piezoresistive sensors,piezoelectric sensors,triboelectric sensors,magnetoelastic sensors,and electrochemical *** also present a comprehensive overview of the challenges that have hindered the scientific advancement in academia and commercialization in the industry.

关键词： bioinspired nanomaterials human–machine interface wearable sensors wearable bioelectronics

Potential for Constraining Propagation Parameters of Galactic Cosmic Rays with the High Energy Cosmic-radiation Detection Facility on Board China's Space Station

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Research in Astronomy and Astrophysics 2023年第8期23卷 290-296页

作者： Zhi-Hui Xu Qiang Yuan Zhi-Cheng Tang xiao-jun bi Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China

Precise measurements of the spectra of secondary and primary cosmic rays are crucial for understanding the origin and propagation of those energetic *** High Energy Cosmic-radiation Detection(HERD)facility on board China's Space Station,which is expected to operate in 2027,will push the direct and precise measurements of cosmic-ray fluxes up to PeV *** this work,we investigate the potential of HERD for studying the propagation of cosmic rays using measurements of boron,carbon,and oxygen *** find that,compared with the current results,the new HERD measurements can improve the accuracy of the propagation parameters by 8%–40%.The constraints on the injection spectra at high energies will also be improved.

关键词： (ISM:)cosmic rays-instrumentation detectors-The Galaxy

Computational Experiments for Complex Social Systems:Integrated Design of Experiment System

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1175-1189页

作者： xiao Xue Xiangning Yu Deyu Zhou xiao Wang Chongke bi Shufang Wang Fei-Yue Wang College of Intelligence and Computing Tianjin UniversityTianjin 300350China School of Software Shandong UniversityJinan 250101China School of Artificial Intelligence Anhui UniversityHefei 230601China School of Geographic and Environmental Sciences Tianjin Normal UniversityTianjin 300387China Institute of Automation Chinese Academy of Sciences Beijing 100190China

Powered by advanced information industry and intelligent technology,more and more complex systems are exhibiting characteristics of the cyber-physical-social systems(CPSS).And human factors have become crucial in the operations of complex social *** mechanical analysis and social simulations alone are powerless for analyzing complex social *** this backdrop,computational experiments have emerged as a new method for quantitative analysis of complex social systems by combining social simulation(e.g.,ABM),complexity science,and domain ***,in the process of applying computational experiments,the construction of experiment system not only considers a large number of artificial society models,but also involves a large amount of data and *** a result,how to integrate various data,model and knowledge to achieve a running experiment system has become a key *** paper proposes an integrated design framework of computational experiment system,which is composed of four parts:generation of digital subject,generation of digital object,design of operation engine,and construction of experiment ***,this paper outlines a typical case study of coal mine emergency management to verify the validity of the proposed framework.

关键词： artificial system operations

Chapter 2 Galactic Gamma-ray Sources

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Chinese Physics C 2022年第3期46卷 36-62页

作者： Yang Chen xiao-jun bi Kun Fang Yi-Qing Guo Ye Liu P.H.Thomas Tam S.Vernetto Zhong-Xiang Wang Rui-Zhi Yang xiao Zhang School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsCASP.O.Box 918Beijing 100049China School of Management Science and Engineering Hebei University of Economics and BusinessShijiazhuangHebei 050061China School of Physics and Astronomy Sun Yat-Sen UniversityGuangzhou 510275China Istituto Nazionale di Astrofisica OATOTorinoItaly Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of Sciences80 Nandan RoadShanghai 200030China Department of Astronomy School of Physical SciencesUniversity of Science and Technology of ChinaHefe 230026China CAS Key Laboratory for Research in Galaxies and Cosmology University of Science and Technology of ChinaHefei 230026China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China

In theγ-ray sky,the highest fluxes come from Galactic sources:supernova remnants(SNRs),pulsars and pulsar wind nebulae,star forming regions,binaries and micro-quasars,giant molecular clouds,Galactic center,and the large extended area around the Galactic *** radiation mechanisms ofγ-ray emission and the physics of the emitting particles,such as the origin,acceleration,and propagation,are of very high astrophysical significance.A variety of theoretical models have been suggested for the relevant physics,and emission with energies E≥10^(14) eV are expected to be crucial in testing *** particular,this energy band is a direct window to test at which maximum energy a particle can be accelerated in the Galactic sources and whether the most probable source candidates such as Galactic center and SNRs are“PeVatrons”.Designed aiming at the very high energy(VHE,>100 GeV)observation,LHAASO will be a very powerful instrument in these astrophysical *** the past decade,great advances have been made in the VHEγ-ray *** than 170 VHEγ-ray sources have been observed,and among them,42 Galactic sources fall in the LHAASO *** a sensitivity of 10 milli-Crab,LHAASO can not only provide accurate spectra for the knownγ-ray sources,but also search for new TeV-PeVγ-ray *** the following sub-sections,the observation of all the Galactic sources with LHAASO will be discussed in details.

关键词： γ-rays cosmic rays radiation mechanisms PeVatrons

An unexpected approach to enhance specific surface area and mesopore amount of polyaniline by Zn doping

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Rare Metals 2024年第9期43卷 4585-4594页

作者： Zhi-Da Zhu Yu-Zhe Han xiao-bi Jing School of Mechanical Engineering Yangzhou University School of Chemistry and Chemical Engineering Yangzhou University

Poly-p-anisidine could be easily fabricated via the oxidative polymerization reaction of p-anisidine using H2O2as the green oxidant. It was unexpectedly found that zinc doping could significantly improve the adsorption ability of the material versus heavy metals such as Pb, Cu,Pd, Ag and Hg. Results of nitrogen adsorption–desorption experiments demonstrated that Zn doping could enhance the specific surface area and mesopore amount of the prepared material, which might facilitate its absorption to metals. This work not only provides a novel material for the treatment of heavy metal-polluted water but also leads to a nice mesoporous catalyst support for environment protection and organic synthesis, i.e. the Zn-doped poly-panisidine can be employed as the catalyst support to prepare Cu@PANI-OMe/Zn or Pd@PANI-OMe/Zn for the oxidative degradation reaction of phenol or Suzuki–Miyaura coupling reactions, respectively. It discloses a new strategy for fabricating the mesoporous polyaniline materials with profound application potential.

关键词： Adsorption Catalysis Porous materials Rare metal concentration Surfaces

bioinformatic approaches of liquid–liquid phase separation in human disease

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中华医学杂志(英文版) 2024年第16期137卷 2024 Jul 19页

作者： Sun jun Chen Yilong bi Ruiye Yuan Yong Yu Haopeng Department of Thoracic Surgery and West China biomedical big Data Center West China Hospital Sichuan University Chengdu Sichuan China Med-X Center for Informatics Sichuan University Chengdu Sichuan China Department of Orthognathic and TMJ Surgery State Key Laboratory of Oral Diseases National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu Sichuan China

biomolecular aggregation within cellular environments via liquid–liquid phase separation (LLPS) spontaneously forms droplet-like structures, which play pivotal roles in diverse biological processes. These structures are closely associated with a range of diseases, including neurodegenerative disorders, cancer and infectious diseases, highlighting the significance of understanding LLPS mechanisms for elucidating disease pathogenesis, and exploring potential therapeutic interventions. In this review, we delineate recent advancements in LLPS research, emphasizing its pathological relevance, therapeutic considerations, and the pivotal role of bioinformatic tools and databases in facilitating LLPS investigations. Additionally, we undertook a comprehensive analysis of bioinformatic resources dedicated to LLPS research in order to elucidate their functionality and applicability. By providing comprehensive insights into current LLPS-related bioinformatics resources, this review highlights its implications for human health and disease.

关键词： Phase separation Liquid–liquid phase separation Disease Phase separation databases bioinformatic tools