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Therapeutic effect of manual massage on early postpartum rectus abdominis separation and postpartum depression

World Journal of Psychiatry 2024年第5期14卷 678-685页

作者： Yun chen xiao-Yan Sun cheng Qian xiao-Xing Zhang Yin-Jian Zhou hong-Yun Zhang Zhen-Wei Xie Department of Gynecology Women’s Hospital School of Medicine Zhejiang UniversityHangzhou 310006Zhejiang ProvinceChina Department of Obstetrics and Gynecology Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina Department of Surgery Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina Department of Obstetrics Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina Department of Ultrasound Women’s Hospital School of Medicine Zhejiang UniversityHangzhou 310006Zhejiang ProvinceChina

BACKGROUND Rectus abdominis separation(DRA)affects pelvic stability and body *** studies have explored the effects of manual massage on early postpartum DRA and postpartum *** To analyze the curative effect of massage on early postpartum DRA and its impact on postpartum depression and thus its ability promote the overall psychosomatic rehabilitation of postpartum *** Data were retrospectively collected on 70 primiparous women with postpartum DRA who underwent rehabilitation at the Postpartum Rehabilitation Center of Huzhou Maternal and Child Health Hospital from October 2022 to September *** patients were divided into the Group S(35 cases,biomimetic electrical stimulation treatment)and Group L(35 cases,biomimetic electrical stimulation combined with manual massage treatment).Baseline data,the edinburgh postpartum depression scale(EPDS)score,and the visual analog scale(VAS)scores for rectus abdominis distance,waist circumference,and lower back pain before and after treatment were *** No significant differences were found in the baseline data,rectus abdominis distance,waist circumference,and VAS and EPDS scores between the two groups before treatment(P>0.05).After treatment,the distance between rectus abdominis and waist circumference in Group L were significantly smaller than those in Group S(P<0.05).Furthermore,lower back pain(VAS score)and the EPDS score in Group L were significantly lower than those in Group S(P<0.05).CONCLUSION Manual massage can significantly reduce early postpartum DRA,waist circumference,and back pain and improve the patient’s mental state and postpartum depression.

关键词： Manual massage Postpartum Rectus abdominis muscle separation Postpartum depression

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Situational Analysis of Malaria Incidence Under Integrated Malaria Service in Hotspot Township-Minbya Township,Rakhine State,Myanmar,2017–2020

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China CDC weekly 2024年第17期6卷 374-377页

作者： Aung Than Oo hong chen ASEAN Centre for Biodiversity Ringgold standard institution D.M.Lantican AvenueUniversity of the Philippines Los Baños LagunaLos BañosPhilippines Center for Global Public Health Chinese Center for Disease Control and PreventionBeijingChina

Introduction:Malaria is a significant public health concern and tropical disease,particularly affecting Myanmar within the Greater Mekong *** annual parasite index(API)exceeds 1 per 10,000 population in the northern seven townships of Rakhine State,with Minbya Township designated as a highburden area for malaria by the World Health Organization(WHO)Myanmar and the National Malaria Control Programme(NMCP).Since 2017,the Malaria reduction intensification plan has been in place in this township to combat the high disease transmission *** study aims to assess the malaria epidemiology in Minbya Township from 2017 to 2020 under the intensification plan for elimination,as well as to evaluate the effectiveness of the integrated strategy in reducing cases in hotspot ***:The study utilized a surveillance study design to collect secondary data from the Malaria surveillance system(MSS)and the epidemiologic monitoring dashboard of Minbya Township,Maruk-U District,located in Rakhine ***:Since 2017,the Malaria prevention and control(P&C)Program in Minbya Township has successfully decreased malaria morbidity,eliminated malaria-related deaths,and bolstered malaria testing capabilities through the participation of village health volunteers(VHVs).Approximately 87%of malaria prevention and control services are executed by the township’s malaria elimination and disease control programs,with additional support from *** API dropped from 13 in 2017 to 2.5 in 2020,with Plasmodium vivax being the most prevalent malaria species,accounting for 55%of ***:The study suggests that early diagnosis and promotion of artemisinin-based combination treatment(ACT),along with strategic planning including expanding active case detection in rural health centers and implementing a communitybasedcommunitybased integrated healthcare approach,are effective and efficient strategies for malaria elimination.

关键词： Malaria prevention epidemiology

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Bending Analysis of Circular Piezoelectric Semiconductor Plates Incorporating Flexoelectricity

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ACTA MECHANICA SOLIDA SINICA 2024年第4期37卷 613-621页

作者： Sun, Liang xiao, Zhengguang Zhang, Chunli chen, Weiqiu Zhejiang Univ Dept Engn Mech Hangzhou 310027 Peoples R China Naval Univ Engn Dept Basic Courses Wuhan 430033 Peoples R China Huanjiang Lab Zhuji 311816 Peoples R China

Based on the three-dimensional (3D) basic equations of piezoelectric semiconductors (PSs), we establish a two-dimensional (2D) deformation-polarization-carrier coupling bending model for PS structures, taking flexoelectricity into consideration. The analytical solutions to classical flexure of a clamped circular PS thin plate are derived. With the derived analytical model, we numerically investigate the distributions of electromechanical fields and the concentration of electrons in the circular PS thin plate under an upward concentrated force. The effect of flexoelectricity on the multi-field coupling responses of the circular PS plate is studied. The obtained results provide theoretical guidance for the design of novel PS devices.

关键词： Piezoelectric semiconductor Plate model Flexoelectricity Multi-field coupling CARRIER DISTRIBUTION PIEZOTRONICS NANOWIRE

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Broadband and fabrication-tolerant 3-dB couplers with topological valley edge modes

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Light(Science & Applications) 2024年第8期13卷 1623-1630页

作者： Guo-Jing Tang xiao-Dong chen Lu Sun Chao-Heng Guo Meng-Yu Li Zhong-Tao Tian Hou-hong chen hong-Wei Wang Qi-Yao Sun Ying-Di Pan Xin-Tao He Yi-Kai Su Jian-Wen Dong School of Physics&State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Advanced Optical Communication Systems and Networks Department of Electronic EngineeringShanghai Jiao Tong UniversityShanghai 200240China

3-dB couplers,which are commonly used in photonic integrated circuits for on-chip information processing,precision measurement,and quantum computing,face challenges in achieving robust performance due to their limited 3-dB bandwidths and sensitivity to fabrication *** address this,we introduce topological physics to nanophotonics,developing a framework for topological 3-dB *** couplers exhibit broad working wavelength range and robustness against fabrication dimensional *** leveraging valley-Hall topology and mirror symmetry,the photonic-crystal-slab couplers achieve ideal 3-dB splitting characterized by a wavelength-insensitive scattering *** analysis confirms the superiority on broad bandwidth of 48 nm and robust splitting against dimensional errors of 20 *** further propose a topological interferometer for on-chip distance measurement,which also exhibits robustness against dimensional *** extension of topological principles to the fields of interferometers,may open up new possibilities for constructing robust wavelength division multiplexing,temperature-drift-insensitive sensing,and optical coherence tomography applications.

关键词： topological splitting insensitive

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Interstitial carbon induces enriched Cu^(δ+) sites in Cu_(2)O nanoparticles to facilitate CO_(2) electroreduction to C_(2+) products

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Nano Research 2024年第8期17卷 7013-7019页

作者： Haoran Wang Rongbo Sun Peigen Liu Haohui Hu chen Ling xiao Han Yi Shi Xusheng Zheng Geng Wu Xun hong Center of Advanced Nanocatalysis(CAN) Department of Applied ChemistryHefei National Laboratory for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China Sinochem Holdings Co Ltd Xiongan New AreaHebei 071700China National Synchrotron Radiation Laboratory(NSRL) University of Science and Technology of ChinaHefei 230029China

The electrochemical CO_(2) reduction reaction(CO_(2)RR)holds significant promise in advancing carbon *** catalysts for the electrochemical CO_(2)RR to multi-carbon(C_(2+))products(e.g.,C_(2)H_(4))under industrial-level current density is urgently needed and ***,we report the Cu_(2)O nanoparticles doped with interstitial carbon atoms(denoted as C-Cu_(2)O NPs)for the conversion of CO_(2) to C_(2+)*** interstitial carbon promotes the C-Cu_(2)O NPs to possess abundant unsaturated Cu–O bonds,leading to a high-density Cu^(δ+)(0<δ<1)*** obtained C-Cu_(2)O NPs exhibited significant Faradic efficiency(FE)of C_(2+) products approaching 76.9%and a partial current density reaching 615.2 mA·cm^(–2)under an industrial-level current density of 800 mA·cm^(–2).Furthermore,the efficient electrosynthesis of C_(2)H_(4) achieved an FE of 57.4%with a partial current density of 459.2 mA·cm^(–2).In situ electrochemical attenuated total reflection Fourier transform infrared spectroscopy and in situ Raman spectroscopy analyses revealed that C-Cu_(2)O NPs stabilized the intermediate*CO and facilitated C–C coupling,leading to increased selectivity towards C_(2+) products.

关键词： CO_(2) electroreduction C-C coupling interstitial carbon *CO coverage industrial-level current density

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A survey of decision making in adversarial games

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Science China(Information Sciences) 2024年第4期67卷 85-112页

作者： Xiuxian LI Min MENG Yiguang hong Jie chen College of Electronics and Information Engineering Tongji University Shanghai Research Institute for Intelligent Autonomous Systems

In many practical applications, such as poker, chess, drug interdiction, cybersecurity, and national defense, players often have adversarial stances, i.e., the selfish actions of each player inevitably or intentionally inflict loss or wreak havoc on other players. Therefore, adversarial games are important in realworld applications. However, only special adversarial games, such as Bayesian games, are reviewed in the literature. In this respect, this study aims to provide a systematic survey of three main game models widely employed in adversarial games, i.e., zero-sum normal-form and extensive-form games, Stackelberg(security) games, and zero-sum differential games, from an array of perspectives, including basic knowledge of game models,(approximate) equilibrium concepts, problem classifications, research frontiers,(approximate) optimal strategy-seeking techniques, prevailing algorithms, and practical applications. Finally, promising future research directions are also discussed for relevant adversarial games.

关键词： adversarial games zero-sum games Stackelberg games differential games Nash equilibrium correlated equilibrium regret

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Extraction of Valuable Metals from Titanium-bearing Blast Furnace Slag by Acid Leaching

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Journal of Wuhan University of Technology(Materials Science) 2024年第2期39卷 376-385页

作者：刘燕 chen Xuegui MAO Shuaidong xiao Yadong LI Jiacong School of Metallurgy Northeastern UniversityShenyang 110819China Key Laboratory of Ecological Metallurgy of Multi-metal Intergrown Ores of Ministry of Education Shenyang 110819China

To realize the resource utilization of the valuable metals in the titanium-containing blast furnace slag,the process route of “hydrochloric acid leaching-electrolysis-carbonization and carbon dioxide capture-preparation of calcium carbonate” was *** this study,the influences of process conditions on the leaching rates of calcium,magnesium,aluminum,and iron and the phases of the leaching residue were investigated for the leaching *** experimental results show that the HCl solution could selectively leach the elements from the titanium-containing blast furnace *** better leaching conditions are the HCl solution concentration of 4 mol/L,the leaching time of 30 min,the ratio of liquid volume to solid gas of 10 mL/g,and the stirring paddle speed of 300 r/*** the conditions,the leaching rates of calcium,magnesium,aluminum,and iron can reach 85.87%,73.41%,81.35%,and 59.08%,and the leaching rate of titanium is 10.71%.The iron and the aluminum are removed from the leachate to obtain iron-aluminum water purification agents,and the magnesium is removed from the leachate to obtain magnesium *** leaching residue phase is dominated by perovskite,followed by magnesium silicate and tricalcium aluminate,and the titaniumrich material could be obtained from the leaching residue by desiliconization.

关键词： titanium-containing blast furnace slag acid leaching valuable metals comprehensive utilization

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Nitrite-catalyzed economic and sustainable bromocyclization of tryptamines/tryptophols to access hexahydropyrrolo[2,3-b]indoles/tetrahydrofuroindolines in batch and flow

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Chinese Chemical Letters 2024年第7期35卷 247-252页

作者： xiao xiao Biao chen Jia-Wei Li Jun-Bo Zheng Xu Wang Hang Zhao Fen-Er chen Institute of Pharmaceutical Science and Technology Collaborative Innovation Center of Yangtze River Delta Region Green PharmaceuticalsZhejiang University of TechnologyHangzhou 310014China College of Chemistry and Chemical Engineering Jiangxi Normal UniversityNanchang 330022China Engineering Center of Catalysis and Synthesis for Chiral Molecules Department of ChemistryFudan UniversityShanghai 200433China Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs Shanghai 200433China

A highly efficient and concise bromocyclization has been successfully achieved,in which tryptamine/tryptophol derivates can be transformed to valuable HPI/TFI scaffolds with economic and green ***,a controllable cascade transformation of bromocyclization and aromatic bromination has also been smoothly achieved to form dibrominated HPIs and *** could be successfully scaled up under both the batch process and a continuous flow *** most remarkable peculiarity of our process over all previous methods is that the generated water is the major ***,successful application of this new protocol has been demonstrated by the pharmaceutical and natural products syntheses.

关键词： Tryptamines and tryptophols Nitrite Economic and sustainable bromocyclization HPI and TFI structures Bath and flow

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SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2285-2297页

作者： Hui Qian chen-hong Ding Fang Liu Shi-Jie chen chen-Kai Huang Meng-Chao xiao Xia-Lu hong Ming-chen Wang Fang-Zhi Yan Kai Ding Ya-Lu Cui Bai-Nan Zheng Jin Ding cheng Luo Xin Zhang Wei-Fen Xie Department of Gastroenterology Changzheng HospitalNaval Medical UniversityShanghaiChina Department of Gastroenterology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Drug Discovery and Design Center CAS Key Laboratory of Receptor ResearchState Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghaiChina Department of Gastroenterology First Affiliated Hospital of Nanchang UniversityNanchangChina Clinical Cancer Institute Center for Translational MedicineNaval Medical UniversityShanghaiChina

The translocation of YAP from the cytoplasm to the nucleus is critical for its activation and plays a key role in tumor ***,the precise molecular mechanisms governing the nuclear import of YAP are not fully *** this study,we have uncovered a crucial role of SOX9 in the activation of ***9 promotes the nuclear translocation of YAP by direct ***,we have identified that the binding between Asp-125 of SOX9 and Arg-124 of YAP is essential for SOX9-YAP interaction and subsequent nuclear entry of ***,we have discovered a novel asymmetrical dimethylation of YAP at Arg-124(YAP-R124me2a)catalyzed by ***-R124me2a enhances the interaction between YAP and SOX9 and is associated with poor prognosis in multiple ***,we disrupted the interaction between SOX9 and YAP using a competitive peptide,S-A1,which mimics anα-helix of SOX9 containing Asp-125.S-A1 significantly inhibits YAP nuclear translocation and effectively suppresses tumor *** study provides the first evidence of SOX9 as a pivotal regulator driving YAP nuclear translocation and presents a potential therapeutic strategy for YAP-driven human cancers by targeting SOX9-YAP interaction.

关键词： interaction interaction precise

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Integrated transcriptomics and metabolomics analysis reveal the molecular mechanism of unsaponifiable matter in delaying aging

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Food Science and Human Wellness 2024年

作者： Dan hong Aijin Ma xiao xiao Mengge Ma Zhou chen Siting Li Yingmin Jia School of Food and Health， Beijing Technology and Business University

Aging is one of the causes of cognitive dysfunction， which seriously affects people's quality of life. Unsaponifiable matter (USM) has antioxidant potential， but the molecular mechanisms that ameliorate aging and cognitive dysfunction are unknown. In this study， we used a galactose-induced brain aging mouse model and systematically analyzed the mechanism of USM in delaying aging in mice by detecting changes in serum and brain by metabolomics and *** was compared with the model group， and non-targeted metabolomics identified 68 (15 up- regulated，53down-regulated) differentially metabolites，andtranscriptomics identified 303 differentially expressed genes (228 up-regulated， 75 down-regulated). Combined multi-omics analyses showed that USM maintains normal brain function by regulating glycolytic processes， the tricarboxylic acid cycle (TCA)， tryptophan metabolism， pyrimidine metabolism， the alanine， aspartate， and glutamate metabolism， and P38MAPK pathway. Meanwhile， USM increased neurotransmitter release from GABAergic synapses and cholinergic synapses by regulating synaptic vesicle cycling. In summary， USM increased energy metabolism and enhanced brain nerve signaling in the mouse brain， thereby delaying brain aging. This investigation offers novel perspectives into the molecular mechanism of USM to mitigate brain aging.

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