检索结果-南通市图书馆

Value of elastography point quantification in improving the diagnostic accuracy of early diabetic kidney disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第23期7卷 3945-3956页

作者： Qiu-Yun Liu Qi Duan xiao-hong fu Li-Qian fu hong-Wei Xia Yong-Lin Wan Department of Ultrasound Naval Military Medical University Affiliated Gongli HospitalShanghai 200135Chi Department of Ultrasound Shanghai Hemujia HospitalShanghai 200336China Department of Nephrology Naval Military Medical University Affiliated Gongli HospitalShanghai 200135China

BACKGROUND Diabetic kidney disease(DKD)is a common complication of *** patient’s prognosis is poor once DKD progresses to advanced *** diagnosis and timely treatment of early DKD are important for improving patient’s prognosis and reducing *** To explore the value of elastography point quantification(ElastPQ)in improving the accuracy of early DKD *** A total of 69 patients with type 2 diabetes were recruited from Naval Military Medical University Affiliated Gongli *** were divided into early DKD group and medium DKD group according to pathological results and urinary albumin excretion rate(UAER).Another 40 patients with simple diabetes were included as the diabetes *** baseline data,laboratory diagnostic indicators,and ultrasound indicators for each patient were *** differences of the indicators in the three groups were *** logistic regression was used to analyze the influencing factors of the development from simple diabetes into early DKD and from early DKD into medium *** operating characteristic analyses of potential indicators in identifying early DKD and medium DKD,and early DKD and simple diabetes were *** Multivariate logistic regression analysis showed that UAER(P0.9].The accuracy of UAER(AUC=0.744),diabetes duration(AUC=0.757),and renocortical YM(AUC=0.782)for the diagnosis of early DKD and simple diabetes were limi

关键词： Diabetic kidney disease Elastography point quantification Young's Modulus Urinary albumin excretion rate Combined diagnosis Diabetes

Activation of the Notch signaling pathway promotes neurovascular repair after traumatic brain injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2015年第8期10卷 1258-1264页

作者： Qi-shan Ran Yun-hu Yu xiao-hong fu Yuan-chao Wen Department of Neurosurgery the First People’s Hospital of Zun Yi/the Third Affiliated Hospital of Zun Yi Medical College

The Notch signaling pathway plays a key role in angiogenesis and endothelial cell formation, but it remains unclear whether it is involved in vascular repair by endothelial progenitor cells after traumatic brain injury. Therefore, in the present study, we controlled the Notch signaling pathway using overexpression and knockdown constructs. Activation of the Notch signaling pathway by Notch1 or Jagged1 overexpression enhanced the migration, invasiveness and angiogenic ability of endothelial progenitor cells. Suppression of the Notch signaling pathway with Notch1 or Jagged1 si RNAs reduced the migratory capacity, invasiveness and angiogenic ability of endothelial progenitor cells. Activation of the Notch signaling pathway in vivo in a rat model of mild traumatic brain injury promoted neurovascular repair. These findings suggest that the activation of the Notch signaling pathway promotes blood vessel formation and tissue repair after brain trauma.

关键词： nerve regeneration endothelial progenitor cells traumatic brain injury Notch signaling pathway cell migration invasion angiogenesis jet PEI? system neural regeneration

The Isometric Extension of the Into Mapping from the Unit Sphere S_1(E) to S_1(l~∞(Г))

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2008年第9期24卷 1475-1482页

作者： xiao hong fu Department of Mathematics,Jiaying College,Meizhou 514015,P.R.China Department of Mathematics Jiaying College Meizhou P. R. China

This paper considers the isometric extension problem concerning the mapping from the unitsphere S(E)of the normed space E into the unit sphere S(l~∞(Γ)).We find a condition under whichan isometry from S,(E)into S1(l~∞(Γ))can be linearly and isometrically extended to the whole *** l~∞(Γ)is universal with respect to isometry for normed spaces,isometric extension problemson a class of normed spaces are *** precisely,if E and F are two normed spaces,and ifV:S(E)→S(F)is a surjective isometry,where c(Γ)■(Γ),then Vcan be extended tobe an isometric operator defined on the whole space.

关键词： l~∞(F) space isometric mapping isometric extension

Wall shear stress can improve prediction accuracy for transient ischemic attack

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第18期7卷 2722-2733页

作者： Qiu-Yun Liu Qi Duan xiao-hong fu Mei Jiang hong-Wei Xia Yong-Lin Wan Department of Ultrasound Naval Military Medical University Affiliated Gongli HospitalShanghai 200000China Department of Ultrasound Shanghai Hemujia HospitalShanghai 200000China Department of Neurology Naval Military Medical University Affiliated Gongli HospitalShanghai 200000China

BACKGROUND Early prediction of transient ischemic attack (TIA) has important clinical value. To date, systematic studies on clinical, biochemical, and imaging indicators related to carotid atherosclerosis have been carried out to predict the occurrence of TIA. However, their prediction accuracy is limited. AIM To explore the role of combining wall shear stress (WSS) with conventional predictive indicators in improving the accuracy of TIA prediction. METHODS A total of 250 patients with atherosclerosis who underwent carotid ultrasonography at Naval Military Medical University Affiliated Gongli Hospital were recruited. Plaque location, plaque properties, stenosis rate, peak systolic velocity, and end diastolic velocity were measured and recorded. The WSS distribution map of the proximal and distal ends of the plaque shoulder was drawn using the shear stress quantitative analysis software, and the average values of WSS were recorded. The laboratory indicators of the subjects were recorded. The patients were followed for 4 years. Patients with TIA were included in a TIA group and the remaining patients were included in a control group. The clinical data, laboratory indicators, and ultrasound characteristics of the two groups were analyzed. Survival curves were plotted by the Kaplan-Meier method. Receiver operating characteristic curves were established to evaluate the accuracy of potential indicators in predicting TIA. Logistic regression model was used to establish combined prediction, and the accuracy of combined predictive indicators for TIA was *** The intraclass correlation coefficients of the WSS between the proximal and distal ends of the plaque shoulder were 0.976 and 0.993, respectively, which indicated an excellent agreement. At the end of the follow-up, 30 patients suffered TIA (TIA group) and 204 patients did not (control group). Hypertension (P = 0.037), diabetes (P = 0.026), homocysteine (Hcy)(P = 0.022), fasting blood glucose (P = 0.034), pla

关键词： Transient ischemic attack Acute ischemic stroke Wall shear stress Atherosclerosis Plaque

Effect of Tillage System on Distribution of Aggregates and Organic Carbon in a Hydragric Anthrosol

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedosphere 2008年第5期18卷 574-581页

作者： GAO Ming LUO You-Jin WANG Zi-Fang TANG xiao-hong WEI Chao-fu College of Resources and Environment Southwest University Chongqing 400716 （China）.

The effect of different tillage systems on the size distribution of aggregates and organic carbon distribution and storage in different size aggregates in a Hydragric Anthrosol were studied in a long-term experiment in Chongqing,China. The experiment included three tillage treatments:conventional tillage with rotation of rice and winter fallow(CT-r) system,no-till and ridge culture with rotation of rice and rape(RT-rr) system,and conventional tillage with rotation of rice and rape(CT-rr) system. The results showed that the aggregates 0.02-0.25 mm in diameter accounted for the largest portion in each soil layer under all treatments. Compared with the CT-r system,in the 0-10 cm layer,the amount of aggregates > 0.02 mm was larger under the RT-rr system,but smaller under the CT-rr system. In the 0-20 cm layer,the organic carbon content of all fractions of aggregates was the highest under the RT-rr system and lowest under the CT-rr system. The total organic carbon content showed a positive linear relationship with the amount of aggregates with diameter ranging from 0.25 to 2 mm. The storage of organic carbon in all fractions of aggregates under the RT-rr system was higher than that under the CT-r system in the 0-20 cm layer,but in the 0-60 cm soil layer,there was no distinct difference. Under the CT-rr system,the storage of organic carbon in all fractions of aggregates was lower than that under the CT-r system;most of the newly lost organic carbon was from the aggregates 0.002-0.02 and 0.02-0.25 mm in diameter.

关键词： aggregates Hydragric Anthrosol organic carbon tillage system

A meta-regression evaluating the effectiveness and prognostic factors of oral phosphodiesterase type 5 inhibitors for the treatment of erectile dysfunction

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2016年第1期18卷 60-65页

作者： Jin-Qiu Yuan Chen Mao Zu-Yao Yang xiao-hong fu Samuel Y Wong Jin-Ling Tang Division of Epidemiology School of Public Health and Primary Care The Chinese University of Hang Kong Hang Kong China Shenzhen Municipal Key Laboratory for Health Risk Analysis Shenzhen Research Institute of The Chinese University of Hang Kong Shenzhen 518055 China Department of Community and Family Medicine The Chinese University of Hang Kong Hang Kong China

The effectiveness of phosphodiesterase type 5 inhibitors （PDE5-1s） for erectile dysfunction （ED） varies considerably among trials, but available studies investigating the factors that affect the effectiveness are few and findings are not consistent. A systematic search was performed in PubMed, Cochrane Library, and EMBASE to identify randomized controlled trials comparing PDE5-1s with placebo for the treatment of ED. The methodological quality of included studies was assessed by the Cochrane Collaboration＇s tool for assessing risk of bias. The associations between prespecified study-level factors and effectiveness were tested by a random effects meta-regression model. This study included 93 trials with 26 139 patients. When all PDE5-1s were grouped together, Caucasian ethnicity was associated with 15.636% （95% confidence interval [CI]： 0.858% to 32.579%） increase in risk ratio （RR） for Global Assessment Questionnaire question-1 （GAQ-1）, and 1.473 （95% CI： 0.406 to 2.338） score increase in mean difference （MD） for posttreatment International Index of Erectile function-Erectile function domain score （IIEF-EF）, compared to Asian ethnicity. A one-score increase in baseline IIEF-EF was associated with -5.635% （95% CI： -9.120% to -2.017%） reduction in RR for GAQ-1, and -0.229 （95% CI： -0.425 to -0.042） score decrease in MD for posttreatment IIEF-EF. In conclusion, PDE5-1s are more effective in Caucasians than Asians, and in patients with more severe ED.

关键词： erectile dysfunction meta-regression phosphodiesterase type 5 inhibitors systematic review

QoS Guaranteed and Adaptive Downstream Bandwidth Utilization Scheme for Ethernet Passive Optical Networks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Electronic Science and Technology 2011年第2期9卷 145-154页

作者： Chen Liu xiao-Mei fu hong-Wei Zhang School of Electronic Information Engineering Tianjin UniversityTianjin 300072China

Dynamic bandwidth allocation（DBA） is an open and hot topic in the Ethernet passive optical network（EPON） ,which is regarded as one of the best choices for next-generation access networks. However,most proposed DBA schemes ignore the quality of service（QoS） guarantee on maximum delay and delay jitter for the real-time traffic and the downstream bandwidth utilization under light upstream load in EPON. In this paper,a new DBA scheme,QoS guaranteed adaptive downstream bandwidth utilization（QoS-ADBU）,is proposed. This scheme can provide better QoS assurance by determining the maximum transmission cycle time according to the maximum acceptable packet delay and delay jitter for real-time traffic. Besides,the downstream utilization can also be improved by adapting the polling frequency to downstream traffic load.

关键词： Downstream bandwidth utilization dynamic bandwidth allocation Ethernet passive optical network quality of service guarantee

Clinical　significance　of　PCR　in　Helicobacter　pylori　DNA　detection　in　human　gastric　disorders

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 1997年第2期3卷 41-43页

作者： XU Guo Ming, JI Xu Huai, LI Zhao Shen, MAN xiao Hua and ZHANG hong fu

AIM To investigate the clinical significance of the PCR assay in the diagnosis of gastric H. pylori infection. METHODS HP infection in gastric antral biopsied specimens was identified by the polymerase chain reaction (PCR) to amplify the specific HP urease gene fragments (PCR HP DNA) in 154 patients with gastrointestinal disorders. HP urease genes oligonucleotide primers specific for HP (16s rRNA) were used. Urease test and ELISA for serum anti HP IgG were also used as control. RESULTS PCR HP DNA was detected in 140(91%) of the 154 patients, 114 and 125 were found infected with HP by urease test and ELISA HP IgG, respectively. There was a marked difference in the HP positive rate between the PCR HP DNA and the urease test or ELISA HP IgG ( P <0 05). The rate of HP infection increased with age although a minority of infected people develop signs and symptoms of gastric disorders. HP infection is closely related to adenocarcinoma in gastric antrum and the downbody of the stomach. CLNCLUSION PCR is a sensitive and specific method for the detection of HP in human gastric tissues. Detection of HP DNA in vivo by this approach might improve the clinical diagnosis and epidemiological research of H. pylori infection.

关键词： peptic ulcer gastritis stomach neoplasms Helicobacter pylori Helicobacter infections polymerase chain reaction

基于约束最小二乘与信赖域的储层参数反演方法

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

地球物理学报 2017年第10期60卷 3969-3983页

作者：林恬孟小红张致付地下信息探测技术与仪器教育部重点实验室中国地质大学(北京)地球物理与信息技术学院中国地质大学(北京) 北京100083

基于包体岩石物理模型的储层参数地震反演方法面临数学形式复杂、多解性强、适应性差、涉及迭代运算等问题,本文提出一种基于约束最小二乘与信赖域的储层参数地震反演方法.该方法基于储层参数与弹性参数关联岩石物理模型,使用最小二乘... 详细信息

基于包体岩石物理模型的储层参数地震反演方法面临数学形式复杂、多解性强、适应性差、涉及迭代运算等问题,本文提出一种基于约束最小二乘与信赖域的储层参数地震反演方法.该方法基于储层参数与弹性参数关联岩石物理模型,使用最小二乘方法构建目标函数和信赖域约束全局寻优求解,有效降低了地震反演多解性,极大提高了收敛速度.特别是通过在最小二乘求解中引入垂向约束,有效提高反演结果的抗噪声能力.经过模型测试和实际资料的应用,验证了方法的可行性和适用性.

关键词：储层参数岩石物理反演最小二乘信赖域算法