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GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms:A Chinese multicenter study of 12-year experience

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World Journal of Gastroenterology 2024年第28期30卷 3403-3417页

作者： Xin-Yu Zeng Ming Zhong Guo-Le Lin Cheng-Guo Li Wei-Zhong Jiang Wei Zhang Li-Jian Xia Mao-Jun Di Hong-Xue Wu xiao-feng liao Yue-Ming Sun Min-Hao Yu Kai-Xiong Tao Yong Li Rui Zhang Peng Zhang Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074Hubei ProvinceChina Department of Gastrointestinal Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of General Surgery Peking Union Medical College HospitalPeking Union Medical CollegeBeijing 100730China Department of Colorectal Surgery Fujian Medical UniversityFuzhou 350401Fujian ProvinceChina Department of Colorectal Surgery Changhai HospitalShanghai 200433China Department of Gastrointestinal Surgery The First Affiliated Hospital of Shandong First Medical UniversityJinan 250118Shandong ProvinceChina Department of Gastrointestinal Surgery Taihe HospitalHubei University of MedicineShiyan 442099Hubei ProvinceChina Department of Gastrointestinal Surgery I Section Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of General Surgery Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and ScienceXiangyang 441021Hubei ProvinceChina Department of Colorectal Surgery Jiangsu Province HospitalNanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina Department of Gastrointestinal Surgery School of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of General Surgery Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080Guangdong ProvinceChina Department of Colorectal Surgery Liaoning Cancer HospitalShenyang 110042Liaoning ProvinceChina

BACKGROUND There is currently a shortage of accurate,efficient,and precise predictive instruments for rectal neuroendocrine neoplasms(NENs).AIM To develop a predictive model for individuals with rectal NENs(R-NENs)using data from a large *** Data from patients with primary R-NENs were retrospectively collected from 17 large-scale referral medical centers in *** forest and Cox proportional hazard models were used to identify the risk factors for overall survival and progression-free survival,and two nomograms were *** A total of 1408 patients with R-NENs were *** grade,T stage,tumor size,age,and a prognostic nutritional index were important risk factors for *** GATIS score was calculated based on these five *** overall survival prediction,the respective C-indexes in the training set were 0.915(95%confidence interval:0.866-0.964)for overall survival prediction and 0.908(95%confidence interval:0.872-0.944)for progression-free survival *** to decision curve analysis,net benefit of the GATIS score was higher than that of a single *** time-dependent area under the receiver operating characteristic curve showed that the predictive power of the GATIS score was higher than that of the TNM stage and pathological grade at all time *** The GATIS score had a good predictive effect on the prognosis of patients with R-NENs,with efficacy superior to that of the World Health Organization grade and TNM stage.

关键词： Rectal neuroendocrine neoplasm Nomogram Random forest Prognosis Overall survival Progression-free survival

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Fast nuclear-spin gates and electrons−nuclei entanglement of neutral atoms in weak magnetic fields

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Frontiers of physics 2024年第2期19卷 179-203页

作者： xiao-feng Shi School of Physics Xidian UniversityXi’an 710071China

We present a novel class of Rydberg-mediated nuclear-spin entanglement in divalent atoms with global laser ***,we show a fast nuclear-spin controlled phase gate of an arbitrary phase realizable either with two laser pulses when assisted by Stark shifts,or with three ***,we propose to create an electrons−nuclei-entangled state,which is named a super bell state(SBS)for it mimics a large Bell state incorporating three small Bell ***,we show a protocol to create a three-atom electrons-nuclei entangled state which contains the three-body W and Greenberger−Horne−Zeilinger(GHZ)states *** protocols possess high intrinsic fidelities,do not require single-site Rydberg addressing,and can be executed with large Rydberg Rabi frequencies in a weak,Gauss-scale magnetic *** latter two protocols can enable measurement-based preparation of Bell,hyperentangled,and GHZ states,and,specifically,SBS can enable quantum dense coding where one can share three classical bits of information by sending one particle.

关键词： nuclear-spin qubit electrons−nuclei entanglement super Bell state Greenberger−Horne−Zeilinger state Rydberg-mediated entanglement quantum dense coding

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Technology of comprehensive disposal and utilization of municipal solid waste (MSW)

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Journal of Environmental Sciences 1999年第3期11卷 378-380页

作者： Liu xiao\|feng, liao Yin\|zhang, Liu Ke\|xin Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu\ 610041, China 中科院成都生物所四川成都 610041 中科院成都生物所四川成都

The project for treating MSW of 200 tons each day was built in Yibin, Sichuan Province of China. The disposal processes are: separation and selection of usable resources; compost and fermentation of “heavy” organic waste (kitchen, garden composting rubbish); incineration of “light” waste (plastic, paper, wood and bamboo etc.) and landfill of inorganic waste. The thermal energy generated in the process can be used as 1/3 of the whole energy for drying fertilizers. In the process, there is no wastewater drainage, and air emissions can be effectively controlled by a series of measures. The sanitary and environmental indicators of disposal site meet the national standards. This project has worked well for two years. It not only disposes of and reduces the MSW, but also retrieves the resource effectively. The organic fertilizer has been applied in the ten thousand acres of fields, with productivity increase by more than 10%.

关键词： municipal solid waste (MSW) comprehensive utilization composted fertilizer.

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Inter-annual variations of dissolved oxygen and hypoxia off the northern Changjiang River(Yangtze River) Estuary in summer from 1997 to 2014

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Acta Oceanologica Sinica 2024年第6期43卷 119-130页

作者： Anqi Liu feng Zhou xiao Ma Qiang Zhao Guanghong liao Yuntao Zhou Di Tian xiaobo Ni Ruibin Ding College of Oceanography Hohai UniversityNanjing 210098China State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Observation and Research Station of Changjiang River Delta Marine Ecosystems Ministry of Natural ResourcesZhoushan 316022China Ningbo Marine Center Ministry of Natural ResourcesNingbo 315000China School of Oceanography Shanghai Jiao Tong UniversityShanghai 200240China Institute of Polar and Ocean Technology Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China

Hypoxia off the Changjiang River Estuary has been the subject of much attention,yet systematic observations have been lacking,resulting in a lack of knowledge regarding its long-term change and *** revisiting the repeated surveys of dissolved oxygen(DO) and other relevant hydrographic parameters along the section from the Changjiang River Estuary to the Jeju-do in the summer from 1997 to 2014,rather different trends were revealed for the dual low-DO *** nearshore low-DO core,located close to the river mouth and relatively stable,shows that hypoxia has become more severe with the lowest DO descen ding at a rate of -0.07 mg/(L·a) and the thickness of low-DO zone rising at a rate of 0.43 m/*** offshore core,centered around 40-m isobath but moving back and forth between 123.5°-125°E,shows large fluctuations in the minimum DO concentration,with the thickness of low-DO zone falling at a rate of -1.55 m/*** probable factors affecting the minimum DO concentration in the two regions also *** the nearshore region,the decreasing minimum DO is driven by the increase in both stratification and primary productivity,with the enhanced extension of the Changjiang River Diluted Water(CDW) strengthening *** the offshore region,the fluctuating trend of the minimum DO concentration indicates that both DO loss and DO supplement are *** DO loss is primarily attributed to bottom apparent oxygen utilization caused by the organic matter decay and is also relevant to the advection of low-DO water from the nearshore *** DO supplement is primarily due to weakened *** analysis also shows that the minimum DO concentration in the nearshore region was extremely low in 1998,2003,2007 and 2010,related to El Ni?o signal in these summers.

关键词： dissolved oxygen low-DO Changjiang River Estuary interannual variations dual-core

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Predictive visual field outcomes after optic chiasm decompressive surgery by retinal vessels parameters using optical coherence tomography angiography

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 365-373页

作者： Wen-Juan Yu Jin xiao Guang-Xin Wang Chang Jiang Wei Zha Rong-feng liao Department of Ophthalmology the First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Neurosurgery the First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Ophthalmology the First People’s Hospital of HefeiHefei 230061Anhui ProvinceChina

AIM:To evaluate the predictive value of superficial retinal capillary plexus(SRCP)and radial peripapillary capillary(RPC)for visual field recovery after optic cross decompression and compare them with peripapillary nerve fiber layer(pRNFL)and ganglion cell complex(GCC).METHODS:This prospective longitudinal observational study included patients with chiasmal compression due to sellar region mass scheduled for decompressive *** estimating equations were used to compare retinal vessel density and retinal layer thickness preand post-operatively and with healthy *** regression models were used to assess the relationship between preoperative GCC,pRNFL,SRCP,and RPC parameters and visual field recovery after ***:The study included 43 eyes of 24 patients and 48 eyes of 24 healthy *** RPC and SRCP vessel density and pRNFL and GCC thickness were lower than healthy controls and higher than postoperative *** best predictive GCC and pRNFL models were based on the superior GCC[area under the curve(AUC)=0.866]and the tempo-inferior pRNFL(AUC=0.824),and the best predictive SRCP and RPC models were based on the nasal SRCP(AUC=0.718)and tempo-inferior RPC(AUC=0.825).There was no statistical difference in the predictive value of the superior GCC,tempo-inferior pRNFL,and tempo-inferior RPC(all P>0.05).CONCLUSION:Compression of the optic chiasm by tumors in the saddle area can reduce retinal thickness and blood *** reduction persists despite the recovery of the visual field after decompression ***,pRNFL,and RPC can be used as sensitive predictors of visual field recovery after decompression surgery.

关键词： sellar region mass retinal vessels optic chiasm optical coherence tomography angiography visual field decompressive surgery

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A Trust Evaluation Mechanism Based on Autoencoder Clustering Algorithm for Edge Device Access of IoT

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Computers, Materials & Continua 2024年第2期78卷 1881-1895页

作者： xiao feng Zheng Yuan Cyber Security Academy Beijing University of Posts and TelecommunicationsBeijing100876China Department of Cyberspace Security Beijing Electronic Science and Technology InstituteBeijing100070China State Grid Info-Telecom Great Power Science and Technology Co. Ltd.Beijing102211China

First,we propose a cross-domain authentication architecture based on trust evaluation mechanism,including registration,certificate issuance,and cross-domain authentication processes.A direct trust evaluation mechanism based on the time decay factor is proposed,taking into account the influence of historical interaction *** weight the time attenuation factor to each historical interaction record for updating and got the new historical record *** refer to the beta distribution to enhance the flexibility and adaptability of the direct trust assessment model to better capture time trends in the historical *** we propose an autoencoder-based trust clustering *** perform feature extraction based on *** leibler(KL)divergence is used to calculate the reconstruction *** constructing a convolutional autoencoder,we introduce convolutional neural networks to improve training efficiency and introduce sparse constraints into the hidden layer of the *** sparse penalty term in the loss function measures the difference through the KL *** clustering is performed based on the density based spatial clustering of applications with noise(DBSCAN)clustering *** the clustering process,edge nodes have a variety of trustworthy attribute *** assign different attribute weights according to the relative importance of each attribute in the clustering process,and a larger weight means that the attribute occupies a greater weight in the calculation of ***,we introduced adaptive weights to calculate comprehensive trust *** experiments prove that our trust evaluation mechanism has excellent reliability and accuracy.

关键词： Cross-domain authentication trust evaluation autoencoder

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Plasma-assisted ammonia synthesis under mild conditions for hydrogen and electricity storage:Mechanisms,pathways,and application prospects

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Frontiers in Energy 2024年第4期18卷 418-435页

作者： feng GONG Yuhang JING Rui xiao Key Laboratory of Energy Thermal Conversion and Process Measurement and Control of the Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjing 210096China

Ammonia,with its high hydrogen storage density of 17.7 wt.%(mass fraction),cleanliness,efficiency,and renewability,presents itself as a promising zero-carbon ***,the traditional Haber−Bosch(H−B)process for ammonia synthesis necessitates high temperature and pressure,resulting in over 420 million tons of carbon dioxide emissions annually,and relies on fossil fuel *** contrast,dielectric barrier discharge(DBD)plasma-assisted ammonia synthesis operates at low temperatures and atmospheric pressures,utilizing nitrogen and hydrogen radicals excited by energetic electrons,offering a potential alternative to the H−B *** method can be effectively coupled with renewable energy sources(such as solar and wind)for environmentally friendly,distributed,and efficient ammonia *** review delves into a comprehensive analysis of the low-temperature DBD plasma-assisted ammonia synthesis technology at atmospheric pressure,covering the reaction pathway,mechanism,and catalyst system involved in plasma nitrogen *** from current research,it evaluates the economic feasibility of the DBD plasmaassisted ammonia synthesis technology,analyzes existing dilemmas and challenges,and provides insights and recommendations for the future of nonthermal plasma ammonia processes.

关键词： plasma catalysis nitrogen fixation ammonia synthesis hydrogen storage catalyst carbon neutralization

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Precisely modulating covalent and coordination bonds in the porous network for highly selective metal ion extraction

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Science China Chemistry 2024年第4期67卷 1039-1040页

作者： Jie Li xiao feng Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials Key Laboratory of Cluster ScienceMinistry of EducationAdvanced Technology Research Institute(Jinan)Frontiers Science Center for High Energy MaterialSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081China

Scandium(Sc)is recognized as a“strategic”and“critical”element by several countries,including the *** Russia,owing to its wide range of applications in high-tech fields such as superconductivity,alloys,lasers,nucle... 详细信息

关键词： alloys coordination network

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Constructal design of printed circuit recuperator for S-CO_(2)cycle via multi-objective optimization algorithm

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Science China(Technological Sciences) 2024年第1期67卷 285-294页

作者： DAN ZhiSong feng HuiJun CHEN LinGen liao NaiBing GE YanLin Institute of Thermal Science and Power Engineering Wuhan Institute of TechnologyWuhan 430205China College of Power Engineering Naval University of EngineeringWuhan 430033China Hubei Provincial Engineering Technology Research Center of Green Chemical Equipment Wuhan 430205China School of Mechanical&Electrical Engineering Wuhan Institute of TechnologyWuhan 430205China AECC Hunan Aviation Powerplant Research Institute Zhuzhou 412002China

Based on a constructal theory,the structure design of a printed circuit recuperator with a semicircular heat transfer channel for supercritical CO_(2)cycle is carried ***,a complex function composed of weighted sum of the reciprocal of total heat transfer rate and total pumping power consumption is regarded as an optimization objective,and total volumes of the recuperator and heat transfer channel are regarded as *** optimal heat transfer channel radius and minimum complex function of the recuperator are *** turns out that heat transfer rate,pumping power consumption,and complex function under the optimal construct of recuperator are reduced by 15.10%,82.44%,and 32.33%,*** exists the optimal single plate channel number which results in the double minimum complex ***,for the purpose of minimizing the reciprocal of heat transfer rate and pumping power consumption,NSGA-II algorithm is used to achieve multi-objective optimization,and the minimum deviation index derived by the decision-making methods is 0.076,which can be taken as multi-objective optimal design scheme for printed circuit recuperator with semicircular heat transfer *** findings presented here can serve as theoretical recommendations for the structure design of printed circuit recuperator.

关键词： constructal theory supercritical CO_(2)cycle printed circuit heat exchanger heat transfer rate pumping power consumption multi-objective optimization

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Proteomic mechanism of Bacillus cereus endospore against plasma-activated water(PAW)

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Food Science and Human Wellness 2024年

作者： xiao Hu Jinsong feng Xinyu liao Tian Ding Ruiling Lü School of Biosystems Engineering and Food Science， Zhejiang University Future Food Laboratory， Innovation Center of Yangtze River Delta， Zhejiang University Ningbo Innovation Center， Zhejiang University

Plasma-activated water (PAW) indicated promising potential in controlling the biological contamination of Bacillus cereus， which eliminated its evolutionary endospore that improves its survival ability. However， the spore inactivation mechanism by PAW at molecular level was not well understood. The mechanism of the Bacillus cereus endospore against PAW at proteomic levels was demonstrated. The Tandem Mass Tag (TMT) labeling was performed. By comparing the treatment groups with control (including PAW and PAW added superoxide dismutase (SOD)) ， the expression of 251 proteins (with the number of 207 up- and 44 down-regulated) and 379 proteins (with the corresponding number of 238 and 141) were drastically affected， separately. The six categories based on the protein-protein interaction (PPI) networks included oxidation-reduction， transport， sporulation and DNA topological change， gene expression， metabolism， and others. The three dehydrogenases (Gene hisD， BC＿2176， and asd) in PAW while oxidoreductase (Gene BC＿0399 and BC＿2529) in SOD were activated to maintain the antioxidation of spores. The proteins (BC＿4271 and BC＿2655) in SOD were dramatically activated， which were involved in the carbohydrate， amino acid， and energy-coupling transport. All the small， acid-soluble spore proteins were activated in both groups to protect the spores’ DNA. In SOD， genes metG2 and rpmC also were considered important factors in translation while this role was played in gene groES but not rpmF in PAW. The PAW activated the biogenesis of cell wall/membrane/envelope and phosphorelay signal transduction system to contribute to the survival of spores whereas the SOD damaged these two processes as well as cell division， chromosome separation， organic acid phosphorylation， base- and nucleotide-excision repair to lead to the death of spores. This would promise to lay the foundation for advancing the study of the intrinsic mechanism of spore killing against PAW and can also provide a reference f

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