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Simulation of GaN micro-structured neutron detectors for improving electrical properties

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Chinese Physics B 2020年第2期29卷 414-419页

作者： Xin-Lei Geng xiao-chuan xia Huo-Lin Huang Zhong-Hao Sun He-Qiu Zhang Xing-Zhu Cui xiao-Hua Liang Hong-Wei Liang School of Microelectronics Dalian University of TechnologyDalian 116024China School of Optoelectronic Engineering and Instrumentation Science Dalian University of TechnologyDalian 116024China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China

Nowadays,the superior detection performance of semiconductor neutron detectors is a challenging *** this paper,we deal with a novel GaN micro-structured neutron detector(GaN-MSND)and compare three different methods such as the method of modulating the trench depth,the method of introducing dielectric layer and p-type inversion region to improve the width of depletion region(W).It is observed that the intensity of electric field can be modulated by scaling the trench *** the other hand,the electron blocking region is formed in the detector enveloped with a dielectric ***,the introducing of p-type inversion region produces new p/n junction,which not only promotes the further expansion of the depletion region but also reduces the intensity of electric field produced by main *** can be realized that all these methods can considerably enhance the working voltage as well as *** them,the improvement on W of GaN-MSND with the p-type inversion region is the most significant and the value of W could reach 12.8μm when the carrier concentration of p-type inversion region is 10^17 cm^-***,the value of W is observed to improve 200%for the designed GaN-MSND as compared with that without additional *** work ensures to the researchers and scientific community the fabrication of GaN-MSND having superior detection limit in the field of intense radiation.

关键词： GaN micro-structured neutron detector depletion region electric field

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan Yu xiao-Li Li xiao-Ting Sun Li-Ting Wang xia Wu Ling-Jie Zhu xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

A novel heat shock protein encoded by KD650 is important for tolerance of pollen tubes to heat stress in Arabidopsis

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A novel heat shock protein encoded by KD650 is important for...

KD127 Plays Important Roles in Pollen Tube and Vegetative Growth in Arabidopsis thaliana

中国遗传学会植物遗传和基因组学专业委员会2007年学术研讨会

作者： Ke-Zhen Yang xiao-Lei Liu chuan xia Li-Qun Chen Xue-Qin Zhang De Ye Key Laboratory of Plant Physiology and Biochemistry,College of Biological Sciences,China Agricultural University,Beijing 100094,China

Control of pollen tube growth is important for successful fertilization in *** understand the genetic mechanisms that control the growth of pollen tubes,we have performed a large scale isolation and characterization of the genes that are involved in the pollen tube growth using the gene-and enhancer-trap technology (Sundaresan et al.,

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KD127 Plays Important Roles in Pollen Tube and Vegetative Gr...

Advances in nuclear detection and readout techniques

2006年拟南芥研究学术研讨会

作者： Ke-Zhen Yang, xiao-Lei Liu, chuan xia, Meng-Meng Zhu, Li-Qun Chen, Xue-Qin Zhang, and De Ye State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University Yuanmingyuan Xilu, Beijing 100094, China.

＜正＞To understand the genetic mechanisms that regulate the formation and development of plant male gametophytes, we are performing a large scale characterization of male gametophytic mutants in Arabidopsis. Here we report the characterization of a novel mutant kd127 that was defective in pollen tube growth. The kd127 mutant was identified by its distorted kanamycin-resistance segregation in a

关键词： KD127 pollen sexual reproduction cell signaling cell patterning Arabidopsis.

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Nuclear Science and Techniques 2023年第12期34卷 281-358页

作者： Rui He xiao‑Yang Niu Yi Wang Hong‑Wei Liang Hong‑Bang Liu Ye Tian Hong‑Lin Zhang Chao‑Jie Zou Zhi‑Yi Liu Yun‑Long Zhang Hai‑Bo Yang Ju Huang Hong‑Kai Wang Wei‑Jia Han Bei Cao Gang Chen Cong Dai Li‑Min Duan Rui‑Rui Fan Fang‑Fa Fu Jian‑Hua Guo Dong Han Wei Jiang xian‑Qin Li Xin Li Zhuo‑Dai Li Yu‑Tie Liang Shun Liao De‑Xu Lin Cheng‑Ming Liu Guo‑Rui Liu Jun‑Tao Liu Ze Long Meng‑Chen Niu Hao Qiu Hu Ran xiang‑Ming Sun Bo‑Tan Wang Jia Wang Jin‑xiang Wang Qi‑Lin Wang Yong‑Sheng Wang xiao‑chuan xia Hao‑Qing Xie He‑Run Yang Hong Yin Hong Yuan Chun‑Hui Zhang Rui‑Guang Zhao Ran Zheng Cheng‑Xin Zhao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516000China Key Laboratory of Particle and Radiation Imaging Department of Engineering PhysicsTsinghua UniversityBeijing 100084China School of Integrated Circuits Dalian University of TechnologyDalian 116020China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Electronic Engineering School Heilongjiang UniversityHarbin 150080China Spallation Neutron Source Science Center Dongguan 523803China Micro‑electronic Department Harbin Institute of TechnologyHarbin 150001China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210034China Liaoning Academy of Materials Shenyang 110167China Istituto Nazionale di Fisica Nucleare Sezione di PerugiaPerugiaItaly School of Mathematics and Physics Chengdu University of TechnologyChengdu 620035China PLAC Key Laboratory of Quark and Lepton Physics(MOE)Central China Normal UniversityWuhan 430079China School of Electronics and Information Northwestern Polytechnical UniversityXi’an 710129China State Key Lab of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China School of Computer Science Northwestern Polytechnical UniversityXi’an 710129China

“A Craftsman Must Sharpen His Tools to Do His Job,”said *** detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the ***,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,*** article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout *** explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community.

关键词： Silicon detector Wide bandgap detector Time projection chamber(TPC) Multigap resistive plate chamber detector(MRPC) Scintillation detector Calorimeters Cherenkov detector Transition radiation detector Artificial intelligence Trigger-less readout

抗拉强度1100MPa以上高强度气瓶的研究

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压力容器 2017年第5期34卷 9-16页

作者：吴传潇马夏康尹谢平毛剑峰浙江工业大学化工机械设计研究所浙江杭州310014 浙江金盾压力容器有限公司浙江绍兴312367

通过研究抗拉强度1100 MPa以上高强度气瓶钢,采用ISO 9809-2:2010壁厚计算公式和有限元技术,对ф229 mm,50 L高强度气瓶进行了设计与分析;并通过"未爆先漏(LBB)"试验对设计进行了验证。结果表明,34CrMo4H高强度气瓶钢在870℃加热、水介... 详细信息

通过研究抗拉强度1100 MPa以上高强度气瓶钢,采用ISO 9809-2:2010壁厚计算公式和有限元技术,对ф229 mm,50 L高强度气瓶进行了设计与分析;并通过"未爆先漏(LBB)"试验对设计进行了验证。结果表明,34CrMo4H高强度气瓶钢在870℃加热、水介质冷却淬火、570~600℃回火空冷热处理条件下,能够满足1100 MPa以上高强度气瓶的设计要求;高强度气瓶的壁厚设计按照ISO 9809-2:2010公式是合理的,但凹底厚度应结合有限元技术进行分析确定,不能直接取值为2倍最小设计壁厚;与GB 5099—1994标准设计相比,高强度气瓶的空瓶质量降低20%以上,实现了气瓶的轻量化,并大大提高了气体充装量;预制裂纹疲劳试验次数在11000次左右,疲劳寿命接近完好气瓶规定值12000次的水平。预制裂纹爆破试验表明,当采用爆破试验方法时预制裂纹深度为实际壁厚的75%左右,当采用疲劳试验方法时预制裂纹深度为实际壁厚的60%~70%,试验结果均能够满足设计要求。

关键词：高强度气瓶未爆先漏(LBB) 34CrMo4H 有限元技术轻量化预制裂纹

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng Wang Guo-Cui Mao Hui-Lin Jiang Bao-xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu xiangbing Wu Wei Wu Ying Wang Yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi xia George Smith Rui Li Nai-Kui Liu xiao-Ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation

Research on the microstructure evolution of Ni-based superalloy cylindrical parts during hot power spinning

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Advances in Manufacturing 2019年第1期7卷 52-63页

作者： Qin-xiang xia Jin-chuan Long Ning-Yuan Zhu Gang-Feng xiao Guangdong Provincial Key Laboratory of Precision Equipment and Manufacturing Technology School of Mechanical and Automobile Engineering South China University of Technology Guangzhou 510640 People's Republic of China School of Mechanical and Electrical Engineering Jiangxi University of Science and Technology Ganzhou 341000 Jiangxi People's Republic of China

To predict the microstructure evolution and reveal the forming mechanism of Ni-based superalloy cylindrical parts during hot power spinning, a finite element method (FEM) model of deformation-heat transfermicrostructure evolution was established using *** software. A numerical simulation was then conducted based on the secondary development of user subroutines, to investigate evolution of the microstructure of a Haynes 230 alloy cylindrical part during hot power spinning. The volume fraction of dynamic recrystallization (DRX) and the grain size of Haynes 230 alloy cylindrical parts during hot power spinning were analyzed. The results showed that the DRX of the spun workpiece was more obvious with an increase in the forming temperature, T, and the total thinning ratio of wall thickness,ψ***, the complete DRX microstructure with fine and uniform grains was obtained when T≥1 100 °C and ψt≥ 2 56%, but the grain size of the spun workpiece decreased slightly with an increase in the roller feed rate, f. The experimental results conformed well with simulation results.

关键词： Hot power spinning Haynes 230 alloy Microstructure evolution Processing parameter Numerical simulation