检索结果-南通市图书馆

Percent free prostate-specific antigen is effective to predict prostate biopsy outcome in Chinese men with prostate-specific antigen between 10.1 and 20.0 ng ml^-1

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2015年第6期17卷 1017-1021,I0012页

作者： Rui Chen Li-Qun Zhou xiao-bing cai Li-Ping Xie Yi-Ran Huang Da-Lin He Xu Gao Chuan-Liang Xu Qiang Ding Qiang wei Chang-Jun Yin Shan-Cheng Ren Fu-Bo Wang Ye Tian Zhong-Quan Sun Qiang Fu Lu-Lin Ma Jun-Hua Zheng Zhang-Qun Ye Ding-Wei Ye Dan-Feng Xu Jian-Quan Hou Ke-Xin Xu Jian-Lin Yuan Xin Gao Chun-xiao Liu Tie-Jun Pan Ying-Hao Sun Department of Urology Shanghai Changhai Hospital Second Military Medical University Shanghai 200433 China ~Department of Urology Peking University First Hospital Institute of Urology Peking University National Urological Cancer Center Beijing 100034 China Department of Health Care PLA Headquarters of the General Staff Guard Bureau Beijing 100017 China Department of Urology First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 Zhejiang China Department of Urology Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200127 China Department of Urology First Affiliated Hospital of Medical School Xi'an:liaotong University Xi'an 710061 China Department of Urology Huashan Hospital Fudan University Shanghai 200040 China Department of Urology West China Hospital Sichuan University Chengdu 610041 Sichuan China State Key Laboratory of Reproductive Medicine Department of Urology The First Affiliated Hospital of Nanjing Medical University Nanjing 210029 China Department of Urology Beijing-Friendship Hospital Capital Medical University Beijing 100050China Department of Urology Huadong Hospital Fudan University Shanghai 20040 China Department of Urology Shanghai :Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China Department of Urology Peking University Third Hospital Beijing 100083 China Department of Urology Tenth People's Hospital Tongji University Shanghai 200072 China Department of Urology Tongji Hospital TongjJ Medical College Huazhong University of Science and TechnologyWuhan 430030 China Fudan University Shanghai Cancer Center Department of Oncology Shanghai 200032 China Department of Urology Shanghai ChangzhengHospital Second Military Medical University Shanghai 200003 China Department of Urology The First Affiliated Hospital of Soochow University Suzhou 215006 China Department of Urology Peking University People's Hospital Beijing 100044 China Department of Urology Xiji

Percent free prostatic-specific antigen （%fPSA） has been introduced as a tool to avoid unnecessary biopsies in patients with a serum PSA level of 4.0-10.0 ng ml^-1, however, it remains controversial whether %fPSA is effective in PSA range of 10.1-20.0 ng ml^-1 in both Chinese and Western population. In this study, the diagnostic performance of %fPSA and serum PSA in predicting prostate cancer （PCa） and high-grade PCa （HGPCa） was analyzed in a multi-center biopsy cohort of 5915 consecutive Chinese patients who underwent prostate biopsy in 22 hospitals across China from January 1, 2010 to December 31, 2013. The indication for biopsy was PSA〉4.0 ng ml^-1 or/and suspicious digital rectal examination. Total and free serum PSA determinations were performed by three types of electrochemiluminescence immunoassays with recalibration to the World Health Organization standards. The diagnostics accuracy of PSA, %fPSA and %fPSA in combination with PSA （%fPSA ＋ PSA） was determined by the area under the receivers operating characteristic curve （AUC）. %fPSA was more effective than PSA in men aged ≥60 years old. The AUC was 0.584 and 0.635 in men aged ≥60 years old with a PSA of 4.0-10.0 ng ml^-1 and 10.1-20.0 ng ml^-1, respectively. The AUC of %fPSA was superior to that of PSA in predicting HGPCa in patients ≥60 years old in these two PSA range. Our results indicated that %fPSA is both statistically effective and clinical applicable to predict prostate biopsy outcome in Chinese patients aged ≥60 years old with a PSA of 4.0-10.0 ng ml^-1 and 10.1-20.0 ng ml^-1.

关键词： Chinese population diagnosis percent free prostate-specific antigen prostate cancer prostate carcinoma tumor antigen prostate-specific antigen

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

黄河三角洲海水灌溉对土壤性质的影响研究

水土保持学报 2004年第1期18卷 19-21页

作者：陈效民白冰蔡成君南京农业大学资源与环境科学学院南京210095

通过2年在黄河三角洲进行海水灌溉对土壤性质的影响研究,结果表明:海水灌溉后土壤剖面中盐分含量有所上升,并在0～100cm土层中有盐分积累现象;土壤中存在的盐分主要以NaCl为主,Na+和Cl-与土壤全盐含量呈直线线性相关,且达到极显著水平;... 详细信息

通过2年在黄河三角洲进行海水灌溉对土壤性质的影响研究,结果表明:海水灌溉后土壤剖面中盐分含量有所上升,并在0～100cm土层中有盐分积累现象;土壤中存在的盐分主要以NaCl为主,Na+和Cl-与土壤全盐含量呈直线线性相关,且达到极显著水平;海水灌溉后土壤的钠吸附比(SAR)在0～60cm土层内有所升高;土壤的pH值在海水灌溉前后基本没有什么变化;残余碳酸钠(RSC)都为负值。因此,在黄河三角洲地区运用海水灌溉不会引起土壤的碱化,并使土壤性质变差,但在海水灌溉过程中必须防治次生盐渍化的发生。

关键词：黄河三角洲海水灌溉土壤性质影响因素

在线全文

学校读者我要写书评

暂无评论

人才质量综合评价及软件支持系统的研究

天津理工学院学报 2003年第4期19卷 72-73页

作者：刘晓琴蔡兵张芬天津理工学院信息技术研究所天津300191

介绍了对"面向21世纪人才素质培养要求,地方工科院校本科教学质量评价方案"课题的研究过程,给出了地方工科院校本科教学质量评价方案指标体系,详细论述了软件支持系统的功能及应用.

关键词：人才质量综合评价软件支持系统地方工科院校教学质量因素重构法权重本科教育

Correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： Peng Li Meifeng cai Shengjun Miao Yuan Li Yu Wang Key Laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same *** addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

Keratinase production and keratin degradation by a mutant strain of Bacillus subtilis

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第1期9卷 60-67页

作者： Cheng-gang cai bing-gan LOU xiao-dong ZHENG College of Food Science and Biosystem Engineering Zhejiang University Hangzhou 310029 China Institute of Biotechnology Zhejiang University Hangzhou 310029 China

A new feather-degrading bacterium was isolated from a local feather waste site and identified as Bacillus subtilis based on morphological, physiochemical, and phylogenetic characteristics. Screening for mutants with elevated keratinolytic activity using N-methyl-N＇-nitro-N-nitrosoguanidine mutagenesis resulted in a mutant strain KD-N2 producing keratinolytic activity about 2.5 times that of the wild-type strain. The mutant strain produced inducible keratinase in different substrates of feathers, hair, wool and silk under submerged cultivation. Scanning electron microscopy studies showed the degradation of feathers, hair and silk by the keratinase. The optimal conditions for keratinase production include initial pH of 7.5, inoculum size of 2% （v/v）, age of inoculum of 16 h, and cultivation at 23 ℃. The maximum keratinolytic activity of KD-N2 was achieved after 30 h. Essential amino acids like threonine, valine, methionine as well as ammonia were produced when feathers were used as substrates. Strain KD-N2, therefore, shows great promise of finding potential applications in keratin hydrolysis and keratinase production.

关键词： Bacillus subtilis Keratin Keratin degradation Keratinase production N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) mutagenesis

在线全文

学校读者我要写书评

暂无评论

无肝素冠状动脉造影术1400例临床分析

第一军医大学学报 2005年第11期25卷 1429-1431页

作者：王挹青王焱蔡彬妮郑剑涛刘文辉陈水龙董俊泽何世华温红梅肖彩滨厦门大学附属中山医院

目的评价无肝素冠状动脉造影术的可行性及安全性。方法总结分析1400例经股动脉行无肝素冠状动脉造影术的患者的临床资料并与354例普通肝素冠状动脉造影术患者进行对照。结果99.3%的病例行选择性冠脉造影成功,手术时间(从穿刺动脉到造影... 详细信息

目的评价无肝素冠状动脉造影术的可行性及安全性。方法总结分析1400例经股动脉行无肝素冠状动脉造影术的患者的临床资料并与354例普通肝素冠状动脉造影术患者进行对照。结果99.3%的病例行选择性冠脉造影成功,手术时间(从穿刺动脉到造影结束)8min￣1h,平均(17.9±11.3)min。冠心病阳性率为72.2%,多支血管病变占49.8%。皮下血肿的发生率为1.8%,假性动脉瘤和动静脉瘘发生率为0.07%,腹膜后血肿、急性心肌梗死、脑卒中及其他体循环栓塞事件发生率为0。结论无肝素冠状动脉造影术不仅安全且具有外周血管并发症少、痛苦小、住院时间短等优点。

关键词：冠状动脉造影肝素并发症

SensFL:Privacy-Preserving Vertical Federated Learning with Sensitive Regularization

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2025年第1期142卷 385-404页

作者： Chongzhen Zhang Zhichen Liu Xiangrui Xu Fuqiang Hu Jiao Dai Baigen cai Wei Wang School of Automation and Intelligence Beijing Jiaotong UniversityBeijing100044China Shuohuang Railway Development Co. Ltd.National Energy GroupCangzhou062350China Beijing Key Laboratory of Security and Privacy in Intelligent Transportation School of Computer Science and TechnologyBeijing Jiaotong UniversityBeijing100044China

In the realm of Intelligent Railway Transportation Systems,effective multi-party collaboration is crucial due to concerns over privacy and data *** Federated Learning(VFL)has emerged as a promising approach to facilitate such collaboration,allowing diverse entities to collectively enhance machine learning models without the need to share sensitive training ***,existing works have highlighted VFL’s susceptibility to privacy inference attacks,where an honest but curious server could potentially reconstruct a client’s raw data from embeddings uploaded by the *** vulnerability poses a significant threat to VFL-based intelligent railway transportation *** this paper,we introduce SensFL,a novel privacy-enhancing method to against privacy inference attacks in ***,SensFL integrates regularization of the sensitivity of embeddings to the original data into the model training process,effectively limiting the information contained in shared *** reducing the sensitivity of embeddings to the original data,SensFL can effectively resist reverse privacy attacks and prevent the reconstruction of the original data from the *** experiments were conducted on four distinct datasets and three different models to demonstrate the efficacy of *** results show that SensFL can effectively mitigate privacy inference attacks while maintaining the accuracy of the primary learning *** results underscore SensFL’s potential to advance privacy protection technologies within VFL-based intelligent railway systems,addressing critical security concerns in collaborative learning environments.

关键词： Vertical federated learning privacy defenses

Corrosion behavior of low alloy steel for cargo oil tank under upper deck conditions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2018年第1期25卷 120-130页

作者： Hao Li Feng Chai cai-fu Yang Chao Li xiao-bing Luo Central Iron and Steel Research Institute Beijing 100081China Qingdao NCS Testing Protection Technology Co. Ltd.Qingdao 266071 Shandong China

A simulated corrosion test apparatus was used to investigate the corrosion behavior of a low alloy steel under simulated upper deck conditions in a cargo oil tank. The estimated corrosion loss of conventional E36 class ship plate steel is 4.27 mm, which is clearly inadequate compared with the standard adopted by International Maritime Organization. Outer rust layer of specimens starts to peel off after 77 days and becomes fragmented after 98 days. X-ray diffraction, scanning electron micros- copy, and Raman spectroscopy revealed that the resulting rust is composed of σ-FeOOH （the main protective phase）, Fe2O3, FeS, elemental S, and FeSO4. FeSO4 in the interface of the base and rust layer leads to localized corrosion. Elemental sulfur forms on the surface of σ-FeOOH, and the quantity and size thereof increase with increasing corrosion time. Furthermore, layered elemental sulfur promotes fracture and peels off the rust layer.

关键词： Low alloy steel Cargo oil tank Upper deck Corrosion film Elemental sulfur

Strengthening and toughening mechanism of a Cu-bearing high-strength low-alloy steel with refined tempered martensite/bainite(M/B)matrix and minor inter-critical ferrite

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2021年第4期28卷 464-478页

作者： Fei Zhu Feng Chai xiao-bing Luo Zheng-yan Zhang cai-fu Yang Department of Structural Steels Central Iron and Steel Research InstituteBeijing 100081China

The microstructure–mechanical property relationship of a Cu-bearing low-carbon high-strength low-alloy steel,subjected to a novel multistage heat treatment including quenching(Q),lamellarization(L)and tempering(T),is *** strength of 989.5 MPa and average toughness at-80℃of 41 J were obtained in this steel after quenching and tempering(QT)heat *** QLT gained a little lower yield strength(982.5 MPa),but greatly enhanced average toughness at-80℃(137 J).To further clarify the strengthening and toughening mechanisms in specimen QLT,parameters of microstructural characteristic and crack propagation process were compared and analyzed for specimens Q,QL,QT and *** microstructure of tempered martensite/bainite(M/B)in specimen QT changed to refined tempered M/B matrix mixed with minor IF(inter-critical ferrite)in specimen ***-rich precipitates existed in tempered M/B for both specimens QT and QLT,as well as in *** with QT,adding a lamellarization step before tempering made the effective grains of specimen QLT refined and also led to coarser Cu-rich precipitates in tempered M/B *** weaker strengthening effect of coarser Cu-rich precipitates should be a key reason for the slightly lower yield strength in specimen QLT than in specimen *** austenite was found in all specimens Q,QL,QT and *** QLT showed purely ductile fracture mode at-80℃due to the refined effective *** greatly improved toughness is mainly attributed to the enhanced energy of crack *** combination of refined microstructure,softened matrix and deformation of minor'soft'IF during crack propagation led to the most superior toughness of specimen QLT among all specimens.

关键词： High-strength low-alloy steel Multistage heat treatment Low-temperature toughness Strengthening mechanism Grain refinement Crack propagation