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局麻下行膝关节关节镜手术的应用体会

中国内镜杂志 2015年第12期21卷 1327-1330页

作者：王玮庄小强白宇黄晖金先跃广西民族医院广西南宁530001 广西壮族自治区人民医院广西南宁530021

目的探讨在膝关节关节镜手术中局部麻醉的可行性和优越性。方法用2%利多卡因20.0 ml+1%盐酸肾上腺素0.5 ml+生理盐水30.0 ml做穿刺点局部浸润麻醉及关节腔内表面麻醉,观察186例局麻下行膝关节关节镜手术患者的麻醉满意度及手术效果。结... 详细信息

目的探讨在膝关节关节镜手术中局部麻醉的可行性和优越性。方法用2%利多卡因20.0 ml+1%盐酸肾上腺素0.5 ml+生理盐水30.0 ml做穿刺点局部浸润麻醉及关节腔内表面麻醉,观察186例局麻下行膝关节关节镜手术患者的麻醉满意度及手术效果。结果所有患者均按计划完成膝关节关节镜下手术,术后无麻醉并发症发生,患者术中麻醉满意度达94.62%。根据日本骨科协会评估治疗分数(JOA)膝骨性关节炎治疗效果判定标准,术后半年平均得分92.5分。术后半年按患者的主观评定分级,优良率达91.94%。结论局部麻醉可满足部分膝关节疾病关节镜手术的需要,局麻下行膝关节关节镜手术完全可行,有安全、简便、对全身状况影响小、麻醉并发症少和费用少等优点。

关键词：局麻膝关节关节镜手术

Effects of the extrusion parameters on microstructure,texture and room temperature mechanical properties of extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 136-146页

作者： Chenjin Zhang Guangyu Yang Lei xiao Zhiyong Kan Jing Guo qiang Li Wanqi Jie State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China College of Materials Science and Engineering Fuzhou UniversityFuzhou 350108China College of Chemistry and Environmental Science Qujing Normal UniversityQujing 655011China

Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed *** dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)*** the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical-rare-earth(RE)*** alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening *** results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.

关键词： Mg-rare earth alloys extrusion temperature extrusion ratio extrusion speed strengthening mechanisms

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

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Science China Chemistry 2025年第1期 174-180页

作者： Fan-xiao Meng Xing-Yu Wang Ka Lu Ju-Song Yang Fu-Min Zhang Ai-Jun Ma Bao Du Yong-qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

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Integration of perioperative features and intragraft TCF7L2 expression to predict lipid metabolic disorder in liver transplant recipients

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Science China Life Sciences 2025年第1期 297-299页

作者： Junbin Zhou Rongli Wei Guanghan Fan Zhengxing Lian Xuanyu Zhang Linsong Tang Zhetuo Qi Haiyang Xie Shusen Zheng qiang Wei xiao Xu Department of Hepatobiliary and Pancreatic Surgery People's Hospital of LishuiAffiliated Lishui Hospital of Wenzhou Medical UniversityThe First Affiliated Hospital of Lishui University NHFPC Key Laboratory of Combined Multi-Organ Transplantation Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryHangzhou First People's Hospital Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of Medicine Department of Urology The Second Affiliated HospitalZhejiang University School of Medicine Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan (Hangzhou) Hospital Hangzhou Medical College Zhejiang University School of Medicine

Dear Editor, Liver transplantation(LT) is the only curative therapy for patients with endstage liver disease(He et al., 2023; Ling et al., 2022). Post-transplant hypertriglyceridemia(PTHT), which has an incidence of up to 32.8% in 6 months after LT, is one of the major post-transplant complications(Toshima et al., 2020).

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The critical role of therapeutic plasma exchange in ABO-incompatible liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2022年第6期21卷 538-542页

作者： Cheng-Zuo Han qiang Wei Meng-Fan Yang Li zhuang xiao Xu Department of Hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China Institute of Organ Transplantation Zhejiang UniversityHangzhou 310003China National Center for Healthcare Quality Management in Liver Transplant Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalHangzhou 310022China

Background:The shortage of donor liver restricts liver transplantation(LT).Nowadays,donor liver with ABO blood group incompatibility between donor and recipient has become an option to expand the source of donor *** it is now possible to perform ABO-incompatible(ABO-I)LT,antibody-mediated rejection(AMR)has been recognized as the primary cause of desperate outcomes after ABO-I ***-A/B antibody is the trigger of immune response to ABO-I LT graft *** plasma ex-change(TPE)can quickly reduce the titer of plasma antibodies and effectively inhibit humoral *** sources:We searched PubMed and CNKI databases using search terms“therapeutic plasma ex-change”,“ABO-incompatible liver transplantation”,“ABO-I LT”,“liver transplantation”,“LT”,“antibody-mediated rejection”,and“AMR”.Additional publications were identified by a manual search of references from key *** relevant publications published before September 30,2020 were included in this ***:Different centers have made different attempts on whether to use TPE,when to use TPE and how often to use ***,the control standard of lectin revision level is always controversial,the target titer varies significantly from center to center,and the standard target titer has not yet been *** has several schemes to reduce antibody titers,but there is a lack of clinical trials that provide standardized ***:TPE is essential for ABO-I ***,further research and clinical trials should be conducted to determine the best regimen for TPE to remove ABO antibodies and prevent AMR.

关键词： Plasma exchange ABO blood group system Blood group incompatibility Liver transplantation Graft rejection

Highly two-photon and X-ray excited long-persistent luminescence in a crystalline host-guest aggregate

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Aggregate

Aggregate 2024年第2期5卷 328-335页

作者： qiang-Sheng Zhang xiao-Dong Zhang Jia-Yi zhuang Mei Pan MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsIGCMEGBRCE for Functional Molecular EngineeringSchool of ChemistrySun Yat-Sen UniversityGuangzhouP.R.China Hainan Provincial Key Laboratory of Fine Chem School of Chemistry and Chemical EngineeringHainan UniversityHaikouP.R.China

As a unique type of supramolecular self-assemblies,crystalline host-guest aggregates have attracted extensive interests in multiple application ***,a crystalline host-guest aggregate LIFM-HG1 was obtained with curcubit[8]uril as the host and carboxypyridinium salt as the ***-crystal structural analysis indicates that the presence of abundant weak interactions in LIFM-HG1 provides a rigid environment for the guest molecule and effectively blocks the external *** analysis and theoretical calculations confirm the presence of robust triplet energy levels in *** more impressively,the intersystem crossing channels of the guest molecules are greatly opened up after the formation of the crystalline host-guest aggregate,resulting in a large k_(isc)of 6.70×10^(7)s^(−1)at room temperature for LIFM-HG1(which is∼0 for pure guest),leading to fascinatingmultichannel(including one-photon,two-photon,and X-ray)excited LPL *** addition,the crystalline LIFM-HG1 has a much higher triplet state luminescence efficiency under X-ray and two-photon excitation than that under single-photon excitation(A_(P)/A_(F)=86.8,44.8,10.7 under the three circumstances,respectively).And the phosphorescent emission intensity of LIFM-HG1 is 27.6 times higher than that of the crystalline guest under X-ray *** a result,LIFM-HG1 shows a long afterglow retention time under both single-and two-photon excitation,and an impressive afterglow retention time of 1 s under X-ray ***,the excellent lysosomal targeting and low cytotoxicity by the formation of host-guest aggregate makes LIFM-HG1 promising to be used as a novel lysosomal-targeted two-photon excited phosphorescent tracer.

关键词： crystalline host-guest aggregate long-persistent luminescence two-photon X-ray excited

The prevalence and risk factors of prostatic calcification： an analysis of 68 705 subjects

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Asian Journal of Andrology 2018年第4期20卷 417-419页

作者： zhuang Tang xiao-Mei WU qiang Wei Lin-Na Wu Department of Urology West China Hospital Sichuan University Chengdu 610000 China Institute of Urology West China Hospital Sichuan University Chengdu 610000 China West China Hospital Physical Examination Center West China Hospital Sichuan University Chengdu 610000 China

Dear Editor, Prostatic calcification is a common condition observed by the urology community. The earliest description was proposed by Donatus in 1586, followed by Pohl in 1737.1 In clinical practice, an overwhelming majority of prostatic calcification cases are discovered incidentally. This issue has attracted considerable interests, albeit its clinical significance continues to stir discussion and debate. Patients with prostatic calcification often seek medical consultation owing to psychological or emotional reasons, thereby incurring a significant burden.

关键词： The prevalence risk factors

Tilting subcategories in extriangulated categories

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Frontiers of Mathematics in China 2020年第1期15卷 225-253页

作者： Bin ZHU xiao zhuang Department of Mathematical Sciences Tsinghua UniversityBeijing 100084China

Extriangulated category was introduced by *** and *** to give a unification of properties in exact categories anjd triangulated categories.A notion of tilting(resp.,cotilting)subcategories in an extriangulated category is defined in this *** give a Bazzoni characterization of tilting(resp.,cotilting)subcategories and obtain an Auslander-Reiten correspondence between tilting(resp.,cotilting)subcategories and coresolving covariantly(resp.,resolving contravariantly)finite subcatgories which are closed under direct summands and satisfy some cogenerating(resp.,generating)*** of the results are given:we show that tilting(resp.,cotilting)subcategories defined here unify many previous works about tilting modules(subcategories)in module categories of Artin algebras and in abelian categories admitting a cotorsion triples;we also show that the results work for the triangulated categories with a proper class of triangles introduced by ***.

关键词： Extriangulated category tilting subcategory Auslander-Reiten correspondence Bazzoni characterization

A hybrid deep neural network based on multi-time window convolutional bidirectional LSTM for civil aircraft APU hazard identification

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Chinese Journal of Aeronautics 2022年第4期35卷 344-361页

作者： Di ZHOU xiao zhuang Hongfu ZUO Civil A viation Key Laboratory of Aircraft Health Monitoring and Intelligent Maintenance College of Civil AviationNanjing University of Aeronautics and AstronauticsNanjing 210016China Department of Mechanical and Industrial Engineering University of TorontoToronto M5S 3G8Canada College of Science Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Safety is one of the important topics in the field of civil aviation. Auxiliary Power Unit(APU) is one of important components in aircraft, which provides electrical power and compressed air for aircraft. The hazards in APU are prone to cause economic losses and even casualties. So,actively identifying the hazards in APU before an accident occurs is necessary. In this paper, a Hybrid Deep Neural Network(HDNN) based on multi-time window convolutional neural network-Bidirectional Long Short-Term Memory(CNN-Bi LSTM) neural network is proposed for active hazard identification of APU in civil aircraft. In order to identify the risks caused by different types of failures, the proposed HDNN simultaneously integrates three CNN-Bi LSTM basic models with different time window sizes in parallel by using a fully connected neural network. The CNN-Bi LSTM basic model can automatically extract features representing the system state from the input data and learn the time information of irregular trends in the time series data. Nine benchmark models are compared with the proposed HDNN. The comparison results show that the proposed HDNN has the highest identification accuracy. The HDNN has the most stable identification performance for data with imbalanced samples.

关键词： Civil aviation Convolutional neural networks Deep neural networks Hazard identification Long short-term memory