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Two Definitions of Life Will Highlight on Physiological Understanding of Six Meridians

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World Journal of Integrated Traditional and Western Medicine 2020年第1期6卷 44-51页

作者： YANG Jie-zuan FANG Hui xiao dang-sheng First Affiliated Hospital College of MedicineZhejiang UniversityState Key Laboratory for Diagnosis and Treatment of Infectious DiseasesHangzhou 310003China Emergency Department the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003China VIP Ward the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003China

Treatise on Cold Pathogenic Diseases is an ancient guideline for traditional Chinese medicine(TCM) clinicians which classified all diseases into six *** Treatise on Cold Pathogenic Diseases, many syndromes are enunciated in simple vocabularies without physiology and pathology, which is always *** seems that a bridge is necessary for physiological and pathological understanding on Treatise on Cold Pathogenic *** past decade, two definition of life in cell and in our body are presented *** both definitions, energy conversion is the core pathways for all organisms which can be regarded as motion of ***, metabolism of energy agents can be seen as yang while gene expression and stem cell proliferation & differentiation(SCPD) should be seen as yin in cell and in our body *** both definitions also outline the physiology and pathology of six meridians in Treatise on Cold Pathogenic Diseases, which can be unveiled as followings: taiyang meridian-elimination of energy and end metabolites;yangming meridian-acquiring energy agents;shaoyin meridian-the conversions of energy agents;taiyin meridian-new born somatic cell attending the metabolism of energy agents and then going to die;shaoyin meridian-storage and activity of stem cell;jueyin meridian-proliferation & differentiation of stem cell to produce somatic *** definitions will ignite new physiological and pathological understandings on Treatise on Cold Pathogenic Diseases.

关键词： Metabolism Stem cell Yin-yang Five phases Six meridians

Some Novel Viewpoints on Physiology and Pathology of TCM Sphygmology

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World Journal of Integrated Traditional and Western Medicine 2020年第2期6卷 62-68页

作者： FANG Hui YANG Jie-zuan xiao dang-sheng Department of Internal Medicine the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310000China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003ZhejiangChina VIP ward the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310000China

In Traditional Chinese Medicine(TCM),pulse manifestation are an essential method for clinicians to make accurate diagnosis while researches on pulse manifestation are also an important direction for the modernization of *** to the viewpoints of TCM,the abnormality of qi,xue,yin and yang will lead to some alterations of pulse manifestations while by detecting these alterations of pulse manifestation,TCM researchers can not only conclude the abnormality of the qi,xue,yin and yang in the patients,make exact diagnose in TCM but also afford the just *** past researches had abstracted all metabolisms in our body into to pathways:energy metabolism which should be regarded as yang and stem cell proliferation&differentiation(SCPD)which should be regarded as *** two pathways support the metabolisms of local tissue and organs while arteries play vital roles for transportation of energy agents and stem cells to local tissue and *** detecting the alterations of pulse manifestations,clinician can conclude the alterations of energy metabolism and SCPD in ***,many novel parameters should be taken into consideration for describing the pulse manifestations and uncovering the physiology and pathology of pulse manifestations.

关键词： Yinyang Pulse manifestations TCM Stem cell Energy metabolism

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试析陕西农业生产民俗的区域差异

安徽农业科学 2006年第23期34卷 6317-6318,6320页

作者：党晓虹西北农林科技大学人文学院陕西杨凌712100

陕西省是我国跨自然地带最多的省区之一,省内地理条件复杂多样,自然条件差异很大,多样的自然地理条件形成了三大主要的农业类型区:即关中-旱作农业类型区、陕南-旱稻兼作农业类型区、陕北-农牧结合农业类型区。不同的农业生产类型,使得... 详细信息

陕西省是我国跨自然地带最多的省区之一,省内地理条件复杂多样,自然条件差异很大,多样的自然地理条件形成了三大主要的农业类型区:即关中-旱作农业类型区、陕南-旱稻兼作农业类型区、陕北-农牧结合农业类型区。不同的农业生产类型,使得各地的农业生产民俗也是丰富多彩、异彩纷呈。重点论述了三大区域在农业生产仪式和祭祀方面的差异。

关键词：陕西地区农业生产习俗区域差异

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用鸡血代替羊血制作血平板

基础医学与临床 2008年第4期28卷 385-386页

作者：党小利渭南职业技术学院渭南校区微生物教研室陕西渭南714000

微生物学试验离不开培养基的制备。根据培养的细菌种类和培养的目的不同，可配置不同种类的培养基：如基础培养基、营养培养基、鉴别培养基等。

关键词：血平板基础培养基制作羊血血代生物学试验鉴别培养基细菌种类

Preparation and physicochemical characterization of a solid dispersion of(3, 5, 6-trimethylpyrazin-2-yl) methyl 3-methoxy-4-[(3, 5, 6-trimethylpyrazin-2-yl) methoxy] benzoate(VA-T) and polyvinylpyrrolidone

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Chinese Journal of Natural Medicines 2015年第11期13卷 861-866页

作者： CAO Sa-Li HOU Peng LI Bin FU Jing YIN Xing-Bin dang xiao-Fang YANG Chun-Jing ZHANG Jin ZHANG Hui LEI Hai-Min NI Jian School of Chinese Materia Medica Beijing University of Chinese Medicine

Ischemic brain injury is a major disease which threatens human health and safety.(3, 5, 6-trimethylpyrazin-2-yl) methyl 3-methoxy-4-[(3, 5, 6-trimethylpyrazin-2-yl) methoxy] benzoate(VA-T), a newly discovered lead compound, is effective for the treatment of ischemic brain injury and its sequelae. But the poor solubility of VA-T leads to poor dissolution and limited clinical application. In order to improve the dissolution of VA-T, the pharmaceutical technology of solid dispersions was used in the present study. VA-T/ polyvinylpyrrolidone(PVP) solid dispersion was prepared by the solvent method. The dissolution studies were carried out and solid state characterization was evaluated by differential scanning calorimetry(DSC), infrared spectroscopy(IR), x-ray diffraction(XRD) and scanning electron microscopy(SEM). The dissolution rate of VA-T was significantly improved by solid dispersion compared to that of the pure drug and physical mixture. The results of DSC and XRD indicated that the VA-T solid dispersion was amorphous. The IR spectra showed the possible interaction between VA-T and PVP was the formulation of hydrogen bonding. The SEM analysis demonstrated that there was no VA-T crystal observed in the solid dispersions. The ideal drug-to-PVP ratio was 1 : 5. In conclusion, the solid dispersion technique can be successfully used for the improvement of the dissolution profile of VA-T.

关键词： VA-T Ischemic stroke Solid dispersions Dissolution Physicochemical characterization

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论中国古代粮食安全问题及其影响因素

中国农史 2008年第1期27卷 24-31页

作者：吴宾党晓虹西北农林科技大学人文学院陕西杨凌712100

粮食所具有的自然属性和社会属性决定着粮食在国家、社会、家庭中的重要地位。尤其在古代以农业生产为基础产业的社会里,粮食问题时刻刺激着封建统治者的神经,粮食出现危机所带来的巨大破坏也影响着古代社会的历史进程和人们的观念文化... 详细信息

粮食所具有的自然属性和社会属性决定着粮食在国家、社会、家庭中的重要地位。尤其在古代以农业生产为基础产业的社会里,粮食问题时刻刺激着封建统治者的神经,粮食出现危机所带来的巨大破坏也影响着古代社会的历史进程和人们的观念文化,形成了举国重粮的良好的风尚,通过研究表明:中国古代社会粮食安全问题确实客观存在,统治者也深知粮食问题的重要性并不遗余力地从生产、仓储、流通等环节提高粮食安全系数。从宏观粮食安全看,除了在春秋战国时期和明清以后粮食的总供应量和总需求量不平衡,出现供需紧张的状况以外,在其他大部分历史时期则供求相对平衡,甚至经常出现供大于求的状况。但是农业生产的波动性所带来的粮食在时间上的不均衡,地区差异引起的粮食在空间上的分布不均衡,以及封建社会不同阶层民众粮食分配不公等三个因素,直接制约着个人和家庭粮食的获取能力,影响着古代粮食的微观安全。可以说,粮食的宏观安全和粮食的微观不安全并存于古代社会,而正是粮食微观上的不安全,导致了粮食问题成为了影响古代中国社会发展、稳定、变迁的最为重要的、直接的要素。作为古代社会保障粮食正常供应的诸如粮食仓储、粮食流通和调剂等各项措施,也是基于以上三个影响粮食微观安全的因素而展开。

关键词：粮食宏观安全粮食微观安全生产波动性地域差异性粮食分配

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错位装配串联蜂窝结构缓冲吸能特性

浙江大学学报（工学版） 2020年第12期54卷 2329-2335页

作者：翁杭建党晓娟张晓晶上海交通大学航空航天学院上海201100 中国航空工业集团公司成都飞机设计研究所四川成都610091

为优化串联蜂窝的缓冲吸能效果与增强蜂窝结构的可设计性,通过平压实验与全尺寸有限元模拟研究装配错位对于串联蜂窝结构力学性能的影响.采用准静态面外压缩实验,对单层蜂窝、双层对位装配蜂窝、双层错位装配蜂窝3种形式的Nomex蜂窝夹... 详细信息

为优化串联蜂窝的缓冲吸能效果与增强蜂窝结构的可设计性,通过平压实验与全尺寸有限元模拟研究装配错位对于串联蜂窝结构力学性能的影响.采用准静态面外压缩实验,对单层蜂窝、双层对位装配蜂窝、双层错位装配蜂窝3种形式的Nomex蜂窝夹层结构进行测试,通过结构变形过程和响应曲线分析变形机理.实验结果表明,双层串联蜂窝相比单层蜂窝结构可以有效改善蜂窝结构的承载能力和吸能效果.错位装配使两层蜂窝同时开始变形,相比对位装配能进一步提升平台应力,消除第2个峰值应力,承载能力和吸能效果均有较大提升.有限元模型通过建立蜂窝细节模拟错位装配效果,模拟与实验结果具有良好的一致性,同时验证了不同材料隔层对串联蜂窝力学性能的影响.

关键词：串联蜂窝错位装配面外压缩缓冲吸能有限元模型

Surgical treatment of Budd-Chiari syndrome:analysis of 221 cases

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Hepatobiliary & Pancreatic Diseases International 2011年第4期10卷 435-438页

作者： xiao-Wei dang,Pei-Qin Xu,Xiu-Xian Ma,Da-Qian Xu,Yan-Ju Zhu and Yong-Shuai Zhang Division of Hepatobiliary and Pancreatic Surgery,First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052,China Division of Hepatobiliary and Pancreatic Surgery First Affiliated Hospital Zhengzhou University Zhengzhou 450052 China

BACKGROUND:Budd-Chiari syndrome (B-CS) refers to post-hepatic portal hypertension and/or inferior vena cava hypertension caused by obstruction of blood flow at the portal cardinal hepatic *** treatments of B-CS include operations on pathological membrane lesions,shunting and combined *** have shown that China,Japan,India and South Africa have a high incidence of *** China,the Yellow River Basin in Henan,Shandong,Jiangsu and Anhui Provinces also have a high incidence,around 10 per 100 ***:The clinical data of 221 B-CS patients were analyzed *** focused on pathological types,surgical methods,effectiveness and complications of treatment,and ***:Based on imaging findings such as color ultrasonography,angiography or magnetic resonance angiography,the 221 patients were divided into 3 types (five subtypes):type Ia (72 patients),type Ib (20),type II (72),type IIIa (33),and type IIIb (24).Surgical procedures included balloon membranotomy with or without stent (65 patients),improved splenopneumopexy (18),radical resection of membrane and thrombus (17),inferior vena cava bypass [29,with cavocaval transflow (13) and cavoatrial transflow (16)],mesocaval shunt (41),splenocaval shunt (25),splenoatrial shunt (12),splenojugular shunt (6),and combined methods (8).The complication rate was 9.05% (20/221) and the perioperative death rate was 2.26% (5/221).All of the patients were followed up from 6 months to 5 *** success rate was 84.6% (187/221),and the recurrence rate was 8.9% (9/101) and 13.5% (13/96) after 1-and 5-year follow-up,***:The rational choice of surgical treatment based on B-CS pathological typing may increase the success rate and decrease the recurrence.

关键词： Budd-Chiari syndrome intervention shunt transflow

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基于脉冲序列核的脉冲神经元监督学习算法

电子学报 2016年第12期44卷 2877-2886页

作者：蔺想红王向文党小超西北师范大学计算机科学与工程学院甘肃兰州730070

脉冲神经元应用脉冲时间编码神经信息,监督学习的目标是对于给定的突触输入产生任意的期望脉冲序列.但由于神经元脉冲发放过程的不连续性,构建高效的脉冲神经元监督学习算法非常困难,同时也是该研究领域的重要问题.基于脉冲序列的核函... 详细信息

脉冲神经元应用脉冲时间编码神经信息,监督学习的目标是对于给定的突触输入产生任意的期望脉冲序列.但由于神经元脉冲发放过程的不连续性,构建高效的脉冲神经元监督学习算法非常困难,同时也是该研究领域的重要问题.基于脉冲序列的核函数定义,提出了一种新的脉冲神经元监督学习算法,特点是应用脉冲序列核构造多脉冲误差函数和对应的突触学习规则,并通过神经元的实际脉冲发放频率自适应地调整学习率.将该算法用于脉冲序列的学习任务,期望脉冲序列采用Poisson过程或线性方法编码,并分析了不同的核函数对算法学习性能的影响.实验结果表明该算法具有较高的学习精度和良好的适应能力,在处理复杂的时空脉冲模式学习问题时十分有效.

关键词：脉冲神经元监督学习脉冲序列核内积脉冲序列学习