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Steady characteristic investigation on passive residual heat removal system of Chinese advanced PWR

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Nuclear Science and Techniques 2008年第1期19卷 58-64页

作者： xiao Zejun xu chuan ZHUO Wenbin CHEN Bingde National Key Laboratory of Bubble Physics ＆ Natural Circulation Nuclear Power Institute of China Chengdu 610041 China

Thermal-hydraulic characteristic investigation on passive residual heat removal system (PRHRS) of Chinese advanced PWR was conducted to provide input data for PRHRS design and to demonstrate the feasibility of unique design features. A total of 237 sets of test data at steady state have been obtained and the main influence factors on the two-phase natural circulation flow rate and residual heat removal capability were identified. On the basis of theory analysis, a correlation of two-phase natural circulation was obtained, and relative errors of 95% test data were less than ±16%. There is a considerable effect of the system status parameters on the threshold of height between heat source and heat sink, and its correlation of two-phase natural circulation system has been obtained. The steady characteristic research shows that PRHRS has the capability of removing the core decay power through natural circulation.

关键词：反应堆核反应能源管理消除系统

Open pit limit optimization considering economic profit,ecological costs and social benefits

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Transactions of Nonferrous Metals Society of China 2021年第12期31卷 3847-3861页

作者： xiao-chuan xu xiao-wei GU Qing WANG Yun-qi ZHAO Zong-kang WANG College of Resource and Civil Engineering Northeastern UniversityShenyang 110819China

Pit limit design has,up to date,focused mainly on maximization of economic profit alone,with environmental and social issues largely *** paper focuses on incorporating both environmental and social issues in the pit limit design process and provides an approach to pit limit optimization that is in compliance with sustainable *** case study demonstrates that ecological costs have a substantial down-sizing effect and social benefits have a substantial up-sizing effect on the optimal pit *** the ecological costs are factored in,the optimal pit limit is 37.5%smaller than the economically optimal pit ***,when the social benefits are factored in,the optimal pit limit is 48.3%larger than the economically optimal *** overall optimal pit limit,with the economic profit,ecological costs and social benefits simultaneously considered,is a result of balancing conflicting goals of maximizing economic profit,minimizing ecological cost,and maximizing social benefit.

关键词： open pit mine pit limit economic profit ecological cost social benefit sustainable development

Open pit waste removal optimization through equipment fleet scheduling

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Transactions of Nonferrous Metals Society of China 2017年第12期27卷 2682-2690页

作者： xiao-wei GU Qing WANG xiao-chuan xu Jian-ping LIU Tai-wei SUN Kun DU College of Resource and Civil Engineering Northeastern University Shenyang 110819 China Dongmei Foundation Company of Shenyang Shenyang 110016 China

A neighborhood search algorithm was proposed to simultaneously schedule the waste removal quantity and the equipment fleet profile over the mine life for open pit *** initial search domain was first defined and a good schedule was obtained as the current best schedule by searching in this ***,progressively narrower neighborhood search domains were constructed around the current best schedule to search for better *** objective is to minimize the present value of waste removal costs over the mine *** resulting schedule from this algorithm provides a complete fleet profile for each year over the mine life:the selected equipment models,the number of equipment units of each model,the age of each unit,as well as the quantity of waste removed.A numerical example of application was provided to demonstrate the feasibility and merits of the algorithm.

关键词： open pit waste removal equipment fleet scheduling neighborhood search

具有Robin边界条件的Schrodinger算子传输特征值密度

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数学学报（中文版） 2022年第6期65卷 959-966页

作者：马利杰徐小川南京信息工程大学数学与统计学院南京210044

本文研究具有Robin边界条件的传输特征值问题,运用指数型整函数的相关性质刻画特征值密度与势函数支撑区间长度的关系.同时,证明传输特征值问题等价于一类边界条件带有谱参数的Sturm-Liouville问题.

关键词：传输特征值零点密度指数型整函数指示函数 Sturm-Liouville问题

一类半直线上Schrödinger算子逆传输特征值问题的稳定性

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数学学报（中文版） 2024年第1期67卷 72-88页

作者：马利杰郭燕徐小川南京信息工程大学数学与统计学院南京210044 南京信息工程大学江苏省应用数学中心南京210044 南京信息工程大学江苏省系统建模与数据分析国际合作联合实验室南京210044

本文研究具有Neumann边界条件的Schrödinger算子逆传输特征值问题的稳定性.当∫_(0)^(1)q(t)dt=0且q(1)≠0时,存在无穷多个实传输特征值.本文在此条件下,运用变换算子理论和Riesz基相关性质,根据谱数据之差给出弱意义和W21范数意义下两... 详细信息

本文研究具有Neumann边界条件的Schrödinger算子逆传输特征值问题的稳定性.当∫_(0)^(1)q(t)dt=0且q(1)≠0时,存在无穷多个实传输特征值.本文在此条件下,运用变换算子理论和Riesz基相关性质,根据谱数据之差给出弱意义和W21范数意义下两势函数差的估计,这些估计蕴含了逆谱稳定性.

关键词：逆谱问题 Schrödinger算子传输特征值问题稳定性有限谱数据

Ultimate pit optimization with ecological cost for open pit metal mines

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Transactions of Nonferrous Metals Society of China 2014年第5期24卷 1531-1537页

作者：胥孝川顾晓薇王青刘剑平王俊东北大学资源与土木工程学院沈阳110819 东煤沈阳基础工程公司沈阳110016 河南理工大学经济管理学院焦作454000

The ecological costs of open pit metal mining are quantified, which include lost value of direct eco-services, lost value of indirect eco-services, prevention and restoration costs, and cost of carbon emission from energy consumption. These ecological costs are incorporated in an iterative ultimate pit optimization algorithm. A case study is presented to demonstrate the influence of ecological costs on pit design outcome. The results show that it is possible to internalize ecological costs in mine designs. The pit optimization outcome shifts considerably to the conservative side and the profitability decreases substantially when ecological costs are accounted for.

关键词： ultimate pit optimization ecological cost open pit metal mine

Morphological Mechanism and Experimental Verification of Self-healing of Basalt-fiber Modified Water-soaked Asphalt

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 171-186页

作者： xiao Minmin DONG Jinyong LI Chunyan GUO xu REN Jianguo School of Urban Construction and Safety Engineering Shanghai Institute of TechnologyShanghai 201418China

This study investigates the mechanism of action of representative molecules of basalt fibers on the healing of water-soaked *** parameters,morphological characteristics,interfacial healing energy,and interfacial healing strength were analyzed using molecular dynamics and macroscopic tests under different time,temperature,and water conditions to evaluate the specific states and critical conditions involved in *** results indicate that basalt-fiber molecules can induce rearrangement and a combination of water-soaked asphalt at the healing *** groups with different bonding states increase the interfacial adsorption capacity of water-soaked *** interaction between basalt fiber molecules and water molecules leads to a"hoop"phenomenon,while aromatics-2 molecules exhibit a"ring band aggregation"*** former reduces the miscibility of water and asphalt molecules,while the latter causes slow diffusion of the ***,a micro-macro dual-scale comparison of interfacial healing strength was conducted at temperatures of 297.15 and 312.15 K to identify the strength transition point and critical temperature of 299.4 K during the self-healing process of basalt-fiber modified water-soaked asphalt.

关键词： water-soaked asphalt basalt-fibers self-healing properties moisture status molecular characterization

Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior

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Neural Regeneration Research 2025年第6期20卷 1721-1734页

作者： Xirong xu Shoumin xuan Shuai Chen Dan Liu Qian xiao Jie Tu Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina University of Chinese of Academy of Sciences BeijingChina Faculty of Life and Health Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with ***, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal *** knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was ob

关键词： anxiety astrocytes basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry glutamate LDN-212320 transporter

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao De-En xu Ming-Lei Wu Ji-chuan Liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response