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基于断裂力学的预应力对底板纵向开裂的影响分析

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结构工程师 2013年第5期29卷 23-27页

作者：吴迅黄仙正姚康同济大学桥梁工程系上海200092 浙江省公路管理局杭州310000

大跨度混凝土桥底板普遍纵向开裂,以断裂力学理论为基础,以临界断裂能为判据,以ABAQUS有限元软件为工具,对某预应力混凝土连续刚构桥进行模拟,采用扩展有限元法分析其初始裂缝的扩展过程,并探讨影响裂缝扩展因素,结果显示合理布置底板... 详细信息

大跨度混凝土桥底板普遍纵向开裂,以断裂力学理论为基础,以临界断裂能为判据,以ABAQUS有限元软件为工具,对某预应力混凝土连续刚构桥进行模拟,采用扩展有限元法分析其初始裂缝的扩展过程,并探讨影响裂缝扩展因素,结果显示合理布置底板纵向预应力可以有效控制底板纵向裂缝扩展。

关键词：断裂力学混凝土桥底板纵向裂缝

小学语文教材性别启蒙教育利弊分析与辩证利用

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教育与教学研究 2017年第4期31卷 101-107页

作者：黄先政成都大学师范学院四川成都610106

小学语文教材中富含着性别启蒙教育的素材,标题中的人物性别社会称谓揭示、插图中的人物性别外貌特征展示、文本中的人物性别特质定位塑造,都有利于对小学生进行性别启蒙教育,但同时存在性别定势的弊端。教师要辩证利用小学语文教材中... 详细信息

小学语文教材中富含着性别启蒙教育的素材,标题中的人物性别社会称谓揭示、插图中的人物性别外貌特征展示、文本中的人物性别特质定位塑造,都有利于对小学生进行性别启蒙教育,但同时存在性别定势的弊端。教师要辩证利用小学语文教材中的素材对学生进行性别启蒙教育:以标题中的人物称谓明示性别取向基本认知;以插图中的人物外貌展示性别形象模仿蓝本;以文本中的人物表现提供性别社会角色体验。

关键词：小学语文教材素材性别启蒙教育

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论诉讼写作的结构思维规律

成都大学学报（社会科学版） 2013年第1期 79-82页

作者：黄先政成都大学师范学院四川成都610106

文章运用系统论的观点和写作思维的原理,分析诉讼文书结构思维操作的内容、过程、方法和原则,结合"非构思"写作理论探讨诉讼写作结构思维的规律。认为诉讼写作根本的相似思维方法所形成的三段论推理思路及其文本化的"递进"、"并列"思维... 详细信息

文章运用系统论的观点和写作思维的原理,分析诉讼文书结构思维操作的内容、过程、方法和原则,结合"非构思"写作理论探讨诉讼写作结构思维的规律。认为诉讼写作根本的相似思维方法所形成的三段论推理思路及其文本化的"递进"、"并列"思维模型深入揭示了诉讼写作结构思维的主要操作规律,对诉讼写作有积极的指导意义;但是,影响诉讼文章主体部分章法安排的因素众多,实现"非构思"写作有较高的难度,是否需要构思,应当因人而异。

关键词：诉讼写作结构思维内结构外结构 “非构思”

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试析穆旦诗歌的结构要素

成都大学学报（社会科学版） 2009年第4期 53-56页

作者：谭梅黄先政成都大学师范学院四川成都610106

本文主要用结构主义的眼光阅读穆旦,通过对诗歌的主要结构要素——爱情、自然、自我等分析,把握诗歌的内在结构。从剖析穆旦诗歌的内在结构这个角度出发,透过诗歌纷繁复杂的表象,找出诗歌的结构要素,以期能进一步阐释穆旦的诗歌。

关键词：穆旦穆旦诗歌诗歌结构要素

Quickly obtaining densely dispersed coherent particles in steel matrix and its related mechanical property

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 111-118页

作者： Xiaoxiao Wang Qingsong huang School of Chemical Engineering Sichuan UniversityChengdu 610065China

Densely distributed coherent nanoparticles(DCN)in steel matrix can enhance the work-hardening ability and ductility of steel *** the routes to this end can be generally classified into the liquid-solid route and the solid-solid ***,the formation of DCN structures in steel requires long processes and complex *** far,obtaining steel with coherent particle enhancement in a short time remains a bottleneck,and some necessary steps remain ***,we show a high-efficiency liquid-phase refining process reinforced by a dynamic magnetic ***-Y-Mn-O particles had an average size of around(3.53±1.21)nm and can be obtained in just around 180 *** small nanoparticles were coherent with the matrix,implying no accumulated dislocations between the particles and the steel *** findings have a potential application for improving material machining capacity,creep resistance,and radiation resistance.

关键词： ferritic steels coherent particles microstructure compression test work hardening

全科医师岗位培训教学计划的制定及相关问题探讨

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广西高教研究 2001年第6期 76-79页

作者：朱卫民黄献珍莫红梅廖江广西医科大学继续教育学院广西南宁530021

通过制定全科医师岗位培训班教学计划 ,探讨、分析本培训教学计划所引发的一些问题并提出解决问题的思路和办法。

关键词：全科医师岗位培训教学计划培训方法教材课程设置

Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

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Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： Fengwen huang Stephen Temitayo Bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

The role of axon guidance molecules in the pathogenesis of epilepsy

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Neural Regeneration Research 2025年第5期20卷 1244-1257页

作者： Zheng Liu Chunhua Pan Hao huang Department of Neurology Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina

Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms and mechanisms of action. Increasing evidence suggests that axon guidance molecules play a role in the structural and functional modifications of neural networks and that the dysregulation of these molecules is associated with epilepsy susceptibility. In this review, we discuss the essential role of axon guidance molecules in neuronal activity in patients with epilepsy as well as the impact of these molecules on synaptic plasticity and brain tissue remodeling. Furthermore, we examine the relationship between axon guidance molecules and neuroinflammation, as well as the structural changes in specific brain regions that contribute to the development of epilepsy. Ample evidence indicates that axon guidance molecules, including semaphorins and ephrins, play a fundamental role in guiding axon growth and the establishment of synaptic connections. Deviations in their expression or function can disrupt neuronal connections, ultimately leading to epileptic seizures. The remodeling of neural networks is a significant characteristic of epilepsy, with axon guidance molecules playing a role in the dynamic reorganization of neural circuits. This, in turn, affects synapse formation and elimination. Dysregulation of these molecules can upset the delicate balance between excitation and inhibition within a neural network, thereby increasing the risk of overexcitation and the development of epilepsy. Inflammatory signals can regulate the expression and function of axon guidance molecules, thus influencing axonal growth, axon orientation, and synaptic plasticity. The dysregulation of neuroinflammation can intensify neuronal dysfunction and contribute to the occurrence of epilepsy. This review delves into the mechanisms associated with

关键词： axon guidance drug-resistant epilepsy epilepsy nerve regeneration nervous system diseases neural pathways neuroinflammatory diseases neuronal plasticity neurons synaptic remodeling

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

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Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin Su Taiqi huang Meiyu Zhang Yanyu Zhang Yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress