检索结果-南通市图书馆

Application of the improved dung beetle optimizer,muti-head attention and hybrid deep learning algorithms to groundwater depth prediction in the Ningxia area,China

引用

Atmospheric and Oceanic Science Letters 2025年第1期18卷 18-23页

作者： Jiarui Cai Bo Sun Huijun Wang Yi zheng Siyu Zhou Huixin Li Yanyan Huang Peishu Zong Collaborative Innovation Center on forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment ChangeNanjing University of Information Science and TechnologyNanjingChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina China Meteorological Administration Key Laboratory of Transportation MeteorologyNanjingChina Jiangsu Meteorological Observatory NanjingChina

Due to the lack of accurate data and complex parameterization,the prediction of groundwater depth is a chal-lenge for numerical *** learning can effectively solve this issue and has been proven useful in the prediction of groundwater depth in many *** this study,two new models are applied to the prediction of groundwater depth in the Ningxia area,*** two models combine the improved dung beetle optimizer(DBO)algorithm with two deep learning models:The Multi-head Attention-Convolution Neural Network-Long Short Term Memory networks(MH-CNN-LSTM)and the Multi-head Attention-Convolution Neural Network-Gated Recurrent Unit(MH-CNN-GRU).The models with DBO show better prediction performance,with larger R(correlation coefficient),RPD(residual prediction deviation),and lower RMSE(root-mean-square error).Com-pared with the models with the original DBO,the R and RPD of models with the improved DBO increase by over 1.5%,and the RMSE decreases by over 1.8%,indicating better prediction *** addition,compared with the multiple linear regression model,a traditional statistical model,deep learning models have better prediction performance.

关键词： Groundwater depth Multi-head attention Improved dung beetle optimizer CNN-LSTM CNN-GRU Ningxia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Passive activity enhances residual control ability in patients with complete spinal cord injury

引用

Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He Jia zheng Hongming Bai Jia-Sheng Rao Guiyun Song Wei Song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Activatable chemiluminescence probe based on four-arm PEGconjugated-pyropheophorbide-a for in vivo autofluorescence-free imaging of peroxynitrite

引用

Science China Chemistry 2025年

作者： Jianmei Ke Lei Ding Ronggui Lian Cheng zheng Wenjun Li Aixian zheng Yupeng Sun Ming Wu Yongyi Zeng Xiaolong Liu Maochun Hong Xiaolong Zhang The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province Mengchao Hepatobiliary Hospital of Fujian Medical University Ganjiang Innovation Academy Chinese Academy of Sciences School of Rare Earths University of Science and Technology of China College of Chemistry Fuzhou University State Key Laboratory of Structure Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences

Peroxynitrite（ONOO-） is a highly reactive nitrogen species that plays pivotal roles in cell signal transduction and physiological or pathological progresses. However, commonly used ONOO-optical imaging probes are still hampered by high background/autofluorescence（fluorescence probe）, short emission wavelength, or poor selectivity in the case of chemiluminescence. Herein,we report a facile method to prepare an activatable chemiluminescence probe（PPA-PEG） with good biocompatibility and functionality for in vivo autofluorescence-free imaging of ONOO-. The PPA-PEG consists of pyropheophorbide-a（PPA）, a typical deep red photosensitizer that acts as both the recognition and signaling element, and 4-arm poly（ethylene glycol）(4-arm PEG), which improves the biosafety and water solubility of probe. These components can self-assemble into nanoparticles（namely PPA-PEG nanoprobe） in aqueous solution. The PPA-PEG nanoprobe showed an ultra-low chemiluminescence signal before interacting with ONOO-, but exhibited good selectivity, high sensitivity and a fast response toward ONOO-. The PPAPEG was successfully applied to image cellular ONOO-changes, as well as the endogenous ONOO-changes in inflammation models and subcutaneous or orthotopic hepatocellular carcinoma（HCC） tumors models in living mice. In vitro and in vivo studies verified the good detection and imaging capabilities of PPA-PEG for peroxynitrite, demonstrating suitable tissue penetration and a high signal-to-background ratio（SBR）. Thus, our nanoprobe can serve as a valuable activatable chemiluminescence imaging tool for studying important peroxynitrite-related chemical and biological applications.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

麸胚挤压稳定化处理对全麦挂面品质特性的影响

引用

食品科学 2019年第19期40卷 156-163页

作者：刘艳香汪丽萍谭斌高琨乔聪聪田晓红孙勇郑先哲刘明吴娜娜翟小童刘金明东北农业大学工程学院黑龙江哈尔滨150030 国家粮食和物资储备局科学研究院北京100037 黑龙江八一农垦大学电气与信息学院黑龙江大庆163319

为研究挤压稳定化处理麸胚对全麦食品品质特性的影响,针对麸胚回添制备的100%全麦压延挂面,比较麸胚挤压前后全麦挂面的营养、色泽、风味、贮藏稳定性等品质的变化。结果表明:相比于麸胚未挤压全麦挂面,麸胚挤压稳定化处理全麦挂面的多... 详细信息

为研究挤压稳定化处理麸胚对全麦食品品质特性的影响,针对麸胚回添制备的100%全麦压延挂面,比较麸胚挤压前后全麦挂面的营养、色泽、风味、贮藏稳定性等品质的变化。结果表明:相比于麸胚未挤压全麦挂面,麸胚挤压稳定化处理全麦挂面的多种宏量营养素、矿物元素含量无显著影响(P>0.05),部分营养指标的变化幅度不高于10%;有利于释放β-胡萝卜素、VB2、植物活性组分,不利于保持VB6、叶酸;亚油酸、α-亚麻酸、十一烷酸及部分氨基酸、总氨基酸含量显著增加(P0.05),其他氨基酸及总氨基酸含量均显著增加(P<0.05);色泽加深,电子鼻反应器响应值显著增加,脂肪酸值、酸度显著增加(P<0.05)。结论:全麦挂面较小麦挂面营养价值更高,但色泽加深,风味物质含量增加,挤压稳定化处理麸胚可改善全麦挂面的品质,提高其贮藏稳定性。

关键词：麸胚挤压稳定化全麦挂面品质评价

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

雷帕霉素联合甲霜·噁霉灵对马铃薯早疫病菌的抑制效应

引用

南方农业 2020年第7期14卷 1-7页

作者：吕秀兰金良郑先喆张美权董攀李正国任茂智重庆大学生命科学学院重庆401331 中国农业科学院都市农业研究所四川成都610213

2018年3—5月,利用菌丝生长速率法,测定雷帕霉素对马铃薯早疫病的抑菌活性,雷帕霉素联合甲霜·噁霉灵的协同效应;并通过透射电镜及扫描电镜在超微结构上观察,揭示雷帕霉素抑制马铃薯早疫病的机制。结果表明,雷帕霉素能有效抑制病原菌菌... 详细信息

2018年3—5月,利用菌丝生长速率法,测定雷帕霉素对马铃薯早疫病的抑菌活性,雷帕霉素联合甲霜·噁霉灵的协同效应;并通过透射电镜及扫描电镜在超微结构上观察,揭示雷帕霉素抑制马铃薯早疫病的机制。结果表明,雷帕霉素能有效抑制病原菌菌丝生长;雷帕霉素可导致病原菌菌丝节间膨大,细胞隔膜消失,胞内细胞器消失及细胞死亡;雷帕霉素联合甲霜·噁霉灵具有明显的协同效应。甲霜·噁霉灵单独处理时,其IC50药物浓度约为0.5 mL·L^-1;雷帕霉素+甲霜·噁霉灵组合处理时,达到IC50所需要的甲霜·噁霉灵的浓度降低为0.05 mL·L^-1。

关键词：雷帕霉素甲霜·噁霉灵马铃薯早疫病菌抑菌效果协同作用

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery

引用

Neural Regeneration Research 2025年第1期20卷 224-233页

作者： Yi Zhang Zhongwu Liu Michael Chopp Michael Millman Yanfeng Li Pasquale Cepparulo Amy Kemper Chao Li Li Zhang zheng Gang Zhang Department of Neurology Henry Ford HospitalDetroitMIUSA Department of Physics Oakland UniversityRochesterMIUSA Department of Pathology Henry Ford HospitalDetroitMIUSA Division of Pharmacology Department of NeuroscienceReproductive and Dentistry SciencesSchool of MedicineUniversity of Naples“Federico Ⅱ”NaplesItaly

Axonal remodeling is a critical aspect of ischemic brain repair processes and contributes to spontaneous functional *** previous in vitro study demonstrated that exosomes/small extracellular vesicles(sEVs)isolated from cerebral endothelial cells(CEC-sEVs)of ischemic brain promote axonal growth of embryonic cortical neurons and that microRNA 27a(miR-27a)is an elevated miRNA in ischemic *** the present study,we investigated whether normal CEC-sEVs engineered to enrich their levels of miR-27a(27a-sEVs)further enhance axonal growth and improve neurological outcomes after ischemic stroke when compared with treatment with non-engineered CEC-sEVs.27a-sEVs were isolated from the conditioned medium of healthy mouse CECs transfected with a lentiviral miR-27a expression *** EVs isolated from CECs transfected with a scramble vector(Scra-sEVs)were used as a *** male mice were subjected to permanent middle cerebral artery occlusion and then were randomly treated with 27a-sEVs or *** array of behavior assays was used to measure neurological *** with treatment of ischemic stroke with Scra-sEVs,treatment with 27a-sEVs significantly augmented axons and spines in the peri-infarct zone and in the corticospinal tract of the spinal grey matter of the denervated side,and significantly improved neurological *** vitro studies demonstrated that CEC-sEVs carrying reduced miR-27a abolished 27a-sEV-augmented axonal *** analysis revealed that 27a-sEVs systemically administered preferentially localized to the pre-synaptic active zone,while quantitative reverse transcription-polymerase chain reaction and Western Blot analysis showed elevated miR-27a,and reduced axonal inhibitory proteins Semaphorin 6A and Ras Homolog Family Member A in the peri-infarct *** of the Clathrin-dependent endocytosis pathway substantially reduced neuronal internalization of *** data provide evidence that 27a-sEVs have

关键词： axonal remodeling cerebral endothelial cells exosomes miR-27a mitochondria Semaphorin 6A small extracellular vesicles stroke

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

农业机械化及其自动化国家特色专业的建设与思考

引用

东北农业大学学报（社会科学版） 2009年第4期7卷 55-57页

作者：王金武郑先哲关正军李文哲陈海涛东北农业大学黑龙江哈尔滨150030

根据教育部国家特色专业建设点的建设原则,针对应用型专业农业机械化及其自动化专业在人才培养目标和特色建设上,提出了以提高人文素质、拓宽口径、构造专业方向知识体系、注重基本技能训练、增强实践能力、优化教学内容等建设思路、方... 详细信息

根据教育部国家特色专业建设点的建设原则,针对应用型专业农业机械化及其自动化专业在人才培养目标和特色建设上,提出了以提高人文素质、拓宽口径、构造专业方向知识体系、注重基本技能训练、增强实践能力、优化教学内容等建设思路、方案,形成以北方农业工程背景为特色、强调学生工程设计意识、创新思维训练和综合素质培养的培养模式,为进一步提升农业机械化及其自动化专业的教学质量。

关键词：教学质量农业机械化特色专业

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

引用

Science China Chemistry 2025年第1期 369-376页

作者： Song-Meng Wang Hao Nian Yan-Fang Wang Li-Shuo zheng Yu-Tao zheng Yi-Wei Dong Liping Huang Xiaoping Wang Wei Jiang Liu-Pan Yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of N-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dual-ligand chiral MOFs exhibiting circularly polarized room temperature phosphorescence for anti-counterfeiting

引用

Science China Chemistry 2025年

作者： Hongrui zheng Qingqing Wang Xinchao Wang Fei Wang Shangda Li Jian Zhang State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fujian Key Laboratory of Polymer Materials College of Chemistry and Materials Science Fujian Normal University

Advanced chiral optical materials exhibiting circularly polarized room-temperature phosphorescence（CPRTP） possess significant research value. This study facilitates the synthesis of chiral metal-organic frameworks（CMOFs） with good CPRTP performance by implementing a dual-ligand strategy. By self-assembling the luminescent ligand H2BIIM with the chiral ligands L-or D-H2IDPA in the presence of Zn（II） ions, two robust three-dimensional（3D） CMOFs were successfully constructed. These complexes demonstrated intense fluorescence and exhibited prolonged yellow room-temperature phosphorescence（RTP） with a duration of up to 6 s. Notably, they exhibited both circularly polarized fluorescence(glum= ±7.57 × 10-3) and CPRTP(glum=±2.68 × 10-3). These unique properties were effectively utilized in the creation of multi-color anti-counterfeiting patterns,underscoring their promising potential for a wide range of applications.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Unveiling an ancient whole-genome duplication event in Stentor,the model unicellular eukaryotes

引用

Science China Life Sciences 2025年

作者： Weibo zheng Chao Li Zhaorui Zhou Xiao Chen Michael Lynch Ying Yan School of Life Sciences Ludong University Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity Ocean University of China Biodesign Center for Mechanisms of Evolution Arizona State University Marine College Shandong University

Whole-genome duplication(WGD) events are widespread across eukaryotes and have played a significant role in moulding the genetic architectures of diverse organisms. In the present study, the newly sequenced genome of a giant ciliated protist, Stentor roeselii, provides an opportunity for the analysis of the collinearity and retention of reciprocal best-hit genes between two Stentor species. As a main result, we have unveiled a previously undetected ancient WGD event shaping the genome of its congener, Stentor coeruleus, a model protist used in cytological and evolutionary studies. Genomes of two congeners, S. coeruleus and S. roeselii, are compared and analyzed, revealing that:(i)the former exhibits a much higher retention rate of colinear-gene pairs(28%) than does S. roeselii, and in S. coeruleus, 75% of genes that have a RBH hit in S. roeselii, have paralogs with high amino-acid identity, consistent with a WGD event in the lineage leading to S. coeruleus;(ii) the S. roeselii genome possesses extremely short intergenic regions, implying that the lengths of intergenic regions are under strong selection;(iii) the unique characteristics of introns may have been shaped in the common ancestor of heterotrichs;(iv) gene families that play a role in activities of multiple protein kinases and voltage-gated ion channels expanded rapidly in the ancestor of both taxa, possibly relating to the remarkable regenerative ability in Stentor. This study offers new insights into the evolutionary dynamics of ciliate genomes,with implications for understanding of the processes underlying the evolution of genomic complexity.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：