检索结果-南通市图书馆

基于数据挖掘探析中医药治疗绝经综合征的用药规律

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

河北中医 2024年第1期46卷 137-141页

作者：赵靖昌高纤维陈思儒徐莲薇上海中医药大学附属龙华医院妇科上海200030

目的基于数据挖掘方法研究探讨中医药治疗绝经综合征(MPS)的用药规律,为中医药治疗MPS提供理论支持。方法通过检索中国知网(CNKI)、万方数据服务平台(Wanfang)、维普数据库(VIP)及中国生物医学文献数据库(CBM)中文数据库,PubMed及Web of... 详细信息

目的基于数据挖掘方法研究探讨中医药治疗绝经综合征(MPS)的用药规律,为中医药治疗MPS提供理论支持。方法通过检索中国知网(CNKI)、万方数据服务平台(Wanfang)、维普数据库(VIP)及中国生物医学文献数据库(CBM)中文数据库,PubMed及Web of Science英文数据库,收集中医药治疗MPS的相关文献。然后将筛选到的文献录入Microsoft Excel 2019表格,建立MPS方药数据库,并对所有药物进行频数、性味归经分析,采用chartcool进行绘图,运用SPSS molder 18.0软件进行关联分析获得核心药物组合,再使用SPSS Statistics 25.0软件对使用频次排名前30的中药进行组间联接的聚类分析。结果共筛选到符合标准文献1162篇,涉及处方1463首,共323味中药,其中方剂使用频次≥100首的药物有56味,使用频次最多的药物是白芍,药物四气以温为主,五味以甘、辛味为主,主要归肝、肾经二经,关联规则分析得到关联较强的核心药对是“女贞子-墨旱莲”,对处方使用频次排名前30的药物进行聚类分析共得到8类药物组合。结论MPS的中医药治疗以补益肝肾为主,“女贞子-墨旱莲”可能是中医药治疗MPS的核心药对,并随证配伍行气、安神、清热之药。

关键词：绝经综合征数据挖掘中药疗法

Relationship between prognosis and angiogenesis,lymphangiogenesis,proliferative cell distribution in gastric cancer

在线全文

学校读者我要写书评

暂无评论

The Chinese-German Journal of Clinical Oncology 2009年第12期8卷 694-698页

作者： YangkunWang Chunfang gao xianwei Zhang Jian Yin Fulin Li Department of Pathology The 150 Central Hospital of Chinese PLA Luoyang 471031 China

Objective： We investigated the relationship between lymphangiogenesis, angiogenesis and cell proliferation in gastric cancer. Methods： We observed the central cancer tissues and the peritumoral tissues of 75 patients with gastric carcinoma by immunohistochemistry. Using D2-40, VEGFR-C and VEGFR-3 detected the microlymphatic density （MLD）, CD34 and CD31 detected the microvessel density （MVD）. The proliferation of the cells was labeled by Ki-67. Results： There were a few atresic streak lymphatic vessels in the central cancer tissues, but in the peritumoral tissues lymphatic increased and dilated, it appears adenoid structure. LMVD in the gastric central area （33.7 ± 14.7） decreased significantly than in the peripheral zone （61.8 ± 22.6; P 〈 0.01）. The differences in the distribution and amount of microvessels were similar to lymphatic vessels. The central area of gastric cancer has a small amount of the distribution of focal Ki-67 positive tumor cells, while around the central area there were a large number of Ki-67 positive tumor cells, especially in one low power field （× 10）. Gastric central area of the Ki-67 positive cells in gastric central area （49.5%） were significant decreasing than in the cancer peripheral zone （73.2%; P 〈 0.05）. Conclusion： The mainly distribution of the neonatal lymphatic vessels, blood vessels and Ki-67 positive carcinoma in gastric cancer is anterior border of carcinoma tissues, especially in one low power field （x 10）. The MLD, MVD and Ki-67 positive carcinoma might be an important index for the prognosis of gastric carcinoma. The more lymphatic microvessel, microvessel and Ki-67 positive carcinoma in the peritumoral tissues, the poorer prognosis, vice versa.

关键词： gastric tumor angiogenesis lymphangiogenesis Ki-67 immunohistochemistry prognosis

Impact of mica on geotechnical behavior of weathered granitic soil using macro and micro investigations

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2250-2266页

作者： xianwei Zhang Xinyu Liu Haodong gao Gang Wang Ran An Zhu Liang State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China School of Civil and Hydraulic Engineering Huazhong University of Science and TechnologyWuhan430074China College of Urban Construction Wuhan University of Science and TechnologyWuhan430065China University of Chinese Academy of Sciences Beijing100049China Guangzhou Urban Planning&Design Survey Research Institute Guangzhou510000China Guangdong Enterprise Key Laboratory for Urban Sensing Monitoring and Early WarningGuangzhou510000China

The micaceous weathered granitic soil(WGS)is frequently encountered in civil engineering worldwide,unfortunately little information is available regarding how mica affects the physico-mechanical behaviors of *** study prepares reconstituted WGS with different mica contents by removing natural mica in theWGS,and then mixes it with commercial mica *** geotechnical behavior as well as the microstructures of the mixtures are *** addition of mica enables the physical indices of WGS to be specific combinations of coarser gradation and high permeability but high Atterberg ***,high mica content in WGS was found to be associated with undesirable mechanical properties,including increased compressibility,disintegration,and swelling potential,as well as poor compactability and low effective frictional *** analysis indicates that the influence of mica on the responses of mixtures originates from the intrinsic nature of mica as well as the particle packing being formed *** exists in the mixture as stacks of plates that form a spongy structure with high compressibility and swelling *** among the plates give the soil high water retention and high Atterberg *** pores are also generated by soil particles with bridging packing,which enhances the permeability and water-soil interactions upon *** study provides a microlevel understanding of how mica dominates the behavior of WGS and provides new insights into the effective stabilization and improvement of micaceous soils.

关键词： Weathered granitic soil(WGS) Mica Microstructure Physical properties Mechanical properties Mechanism

Copper-catalyzed C(sp)-H aryl amination enables modular synthesis of quinolines and 2-quinolinones

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第2期67卷 595-603页

作者： Yang gao Haixia Li Simin Yang Yanping Huo Qian Chen xianwei Li Zhe Wang Xiao-Qiang Hu School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou510006China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory Jieyang515200China Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education&Hubei Key Laboratory of Catalysis and Materials Science School of Chemistry and Materials ScienceSouth-Central University for NationalitiesWuhan430074China

Herein,we disclose a novel copper-catalyzed C(sp)-H aryl amination of terminal alkynes with anthranils,enabling the rapid generation of highly reactive secondary N-aryl ynamines for the modular synthesis of structurally diverse C2-substituted quinolines and *** in-situ formed carbonyl-ynamines are prone to tautomerize to carbonyl-ketenimines,which can efficiently react with a series of nucleophiles,including amines,alcohols,phenols,thiols,thiophenols,active-methylene compounds,and even water to produce various quinoline derivatives with the generation of H_(2)O as a sole and green *** method also unlocks a practical route to create various quinoline-fused heterocycles and can be successfully applied to the late-stage modification of complex molecules and the concise synthesis of bioactive *** studies reveal a coppercatalyzed inner-sphere nitrene transfer process by using anthranils as novel aryl nitrene precursors.

关键词： copper catalysis anthranils C(sp)-H aryl amination carbonyl-ketenimines quinolines

A closed sample cell and co-used furnace designed for micro-Raman spectra study on volatile melts

在线全文

学校读者我要写书评

暂无评论

A closed sample cell and co-used furnace designed for micro-...

提高浅层地震成像品质的处理技术——以川中地区沙溪庙组为例

第十六届全国光散射学术会议

作者： Hu xianwei,gao Bingliang,Liu Jingjing,Shi Zhongning,Wang Zhaowen (School of Materials and Metallurgy,Northeastern University,Shenyang 110004)

＜正＞There are some difficulties in sample cell design for Raman spectrum measurements of the high-temperature volatile melts,especially the molten fluoride or chloride which is strongly corrosive. Generally,the cell should meet the requirement of anti-corrosive and anti-heat attack,and the thermal gradients of the cell should be low enough to ensure the temperature measurement *** the present study,a closed cell idea for micro-Raman spectrum measurement of volatile liquid is *** sample cell and furnace is described in *** spectra of various volatile liquids obtained by using

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

石油地球物理勘探 2020年第S01期55卷 56-63,6-7页

作者：干大勇高宪伟朱丹杨广广吕龑韩嵩中国石油西南油气田公司勘探开发研究院四川成都610041 东方地球物理公司研究院河北涿州072751 四川省地质矿产勘查开发局区域地质调查队四川成都610000

川中地区浅层沙溪庙组河道砂岩较发育,是该区新一轮的勘探开发目标层系。针对川中地区浅层地震资料存在的低分辨率和低信噪比等问题和难点,运用GeoEast软件开展保真、保幅、提高分辨率的数据处理。首先分析原始资料,找出处理难点;再分... 详细信息

川中地区浅层沙溪庙组河道砂岩较发育,是该区新一轮的勘探开发目标层系。针对川中地区浅层地震资料存在的低分辨率和低信噪比等问题和难点,运用GeoEast软件开展保真、保幅、提高分辨率的数据处理。首先分析原始资料,找出处理难点;再分别对静校正、叠前保幅去噪、叠前时间偏移和道集优化等方面开展处理试验,优选适合研究区特点的处理参数及流程;最后进行全工区资料的批量处理。最终得到一套波组特征清晰、信噪比较高、浅层同相轴连续性好、偏移归位合理的高分辨率地震资料,为后续的河道砂岩储层精细预测及含气性检测奠定了基础。

关键词： GeoEast 四川盆地沙溪庙组处理流程静校正

在线全文

学校读者我要写书评

暂无评论

商务英语中模糊语言的翻译策略

中国电力教育 2009年第3期 244-246页

作者：高现伟许昌学院外国语学院

语言的模糊性是语言的重要特征之一。模糊性表现在语言的语音、词汇、语法以及跨文化交际产生的模糊性等。商务英语翻译既要力求准确,又要坚持忠实,商务英语中的模糊语言成为翻译的矛盾。本文旨在通过分析模糊语言在商务英语中的表现和... 详细信息

语言的模糊性是语言的重要特征之一。模糊性表现在语言的语音、词汇、语法以及跨文化交际产生的模糊性等。商务英语翻译既要力求准确,又要坚持忠实,商务英语中的模糊语言成为翻译的矛盾。本文旨在通过分析模糊语言在商务英语中的表现和语用功能,研究商务英语中的模糊语言翻译方法。

关键词：商务英语模糊语言翻译

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

椭圆曲线点乘算法的软硬件协同设计研究

计算机工程与应用 2006年第11期42卷 100-102,208页

作者：董秀则高献伟刘姝孙建树北京电子科技学院北京100070

椭圆曲线密码体制是一种基于代数曲线的公开密码体制,其中曲线的点乘速度决定了该密码体制的速度。以NiosII为核心的SOPC技术的发展代表了半导体和嵌入式系统的发展方向。文章在NiosII处理器上对椭圆曲线点乘算法给予了实现,并给出与805... 详细信息

椭圆曲线密码体制是一种基于代数曲线的公开密码体制,其中曲线的点乘速度决定了该密码体制的速度。以NiosII为核心的SOPC技术的发展代表了半导体和嵌入式系统的发展方向。文章在NiosII处理器上对椭圆曲线点乘算法给予了实现,并给出与8051单片机环境实现的速度比较分析,最后使用软硬件协同设计的方式进一步提高椭圆曲线点乘速度。

关键词： NiosⅡ SOPC co-design 椭圆曲线

基于FPGA的进位存储大数乘法器的改进与实现

在线全文

学校读者我要写书评

暂无评论

计算机工程与应用 2017年第21期53卷 58-61页

作者：张晓楠高献伟董秀则西安电子科技大学通信工程学院西安710071 北京电子科技学院电子系北京100070

提出了一种基于FPGA的进位存储的大数乘法器的改进算法,该算法采用串并混合结构可以在一个时钟内完成多次迭代计算,减少了完成一次运算的时钟数,因此有效地提高了大数乘法器的速度。最后硬件结构设计在Altera Stratix Ⅱ EP2S90F1508C3... 详细信息

提出了一种基于FPGA的进位存储的大数乘法器的改进算法,该算法采用串并混合结构可以在一个时钟内完成多次迭代计算,减少了完成一次运算的时钟数,因此有效地提高了大数乘法器的速度。最后硬件结构设计在Altera Stratix Ⅱ EP2S90F1508C3上实现,给出了192位、256位以及384位的乘法器性能分析,其中,192位可达到0.18μs,256位达到0.27μs,384位达到0.59μs,速度上都提高了3.5倍左右。

关键词：大数乘法串并混合结构多次迭代现场可编程门阵列