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Effect of hydrophilic silica nanoparticles on hydrate formation during methane gas migration in a simulated wellbore

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Petroleum 2021年第4期7卷 485-495页

作者： Meng Xu xiangyu fang Fulong Ning Wenjia Ou Ling Zhang Dongdong Wang Faculty of Engineering China University of GeosciencesWuhanHubei430074China Anhui Nuclear Exploration Technology Central Institute Wuhu241000China National Center for International Research on Deep Earth Drilling and Resource Development China University of GeosciencesWuhanHubei430074China

Natural gas hydrates are mostly formed in low-permeability and fractured muddy sedimentary forma*** suitable nanoparticles to the drilling fluid system can improve its filtrate resistance and fracture plugging,and effectively weaken the invasion of drilling fluid into the ***,it is likely that nanoparticles promote hydrate formation and accumulation in wellbores which will induce ***,this study investigated the effect of hydrophilic silica nanoparticles with particle sizes of 30 nm,60 nm,and 80 nm and concentrations of 0.5e4.0 wt%on hydrate formation during upward migration of methane gas using a dynamic simulation system for hydrate formation in a well*** experimental results show that under the condition of methane gas migration,hydrophilic silica nanoparticles inhibit hydrate *** inhibition effect increased with the growth in the particle size under a constant concentration,whereas it first increased and then decreased with increasing nanoparticle concentration under a constant particle *** strongest inhibition effect was observed at a hydrophilic silica nanoparticle concentration of 2.0 wt%.The influence of hydrophilic silica nanoparticles on hydrate formation may be mainly determined by their hydrophilic properties,heat and mass transfer,and gas migration in the *** research indicates that hydrophilic silica nanoparticles can be added to hydrate drilling fluid systems if their concentration can be properly controlled.

关键词： Natural gas hydrate Drilling fluid Hydrophilic silica nanoparticles Methane gas migration

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Experimental study on sand production and coupling response of silty hydrate reservoir with different contents of fine clay during depressurization

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Petroleum 2023年第1期9卷 72-82页

作者： xiangyu fang Dianheng Yang Fulong Ning Linjie Wang Zhichao Liu Yanjiang Yu Wenwei Xie Hongfeng Lu Yanlong Li Meng Xu Faculty of Engineering China University of GeosciencesWuhan430074China Anhui Nuclear Exploration Technology Central Institute Wuhu241000China National Center for International Research on Deep Earth Drilling and Resource Development China University of GeosciencesWuhan430074China MLR Key Laboratory of Marine Mineral Resources Guangzhou Marine Geological SurveyGuangzhou510075China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao266071China

To further understand the characteristics of clay and sand production(hereafter collectively referred to as sand production)and to provide optimization designs of sand control schemes are critical for gas production from clayey silt natural gas hydrate reservoirs in the South China ***,gas-water-sand production behavoirs and coupling reservoir subsidence characteristics before,during,and after hydrate dissociation of the clayey silt hydrate reservoirs with different clay contents(5%,10%,15%,20%,25%,and 30%)have been studied through a self-developed experimental *** results show that with the increase of clay content,the total mass of sand production first increases and then decreases,and it reaches maximum when the clayey content is 20%.The sand production is the lowest before hydrate dissociation and increases significantly during hydrate dissociation,which mainly occurs in the high-speed gas and water production stage at the beginning of hydrate *** hydrate dissociation,the sand production decreases *** the whole depressurization process,the clay and free sand particles generally move to the sand outlet due to the fluid driving force and overlying stress ***,for conditions of high clay contents,those particles fail to pass through the sand control screen and gradually accumulate and block the screen by forming a mud cake,which greatly reduce the permeability of the screen and limite sand production as well as gas and water *** research lays a foundation for sand production prediction and sand control scheme selection during gas recovery from clayey silty hydrate reservoirs that greatly need to consider a balance between sand control and gas productivity.

关键词： Natural gas hydrate Clayey silt reservoir Clay content Depressurization Sand production Sand control

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High Fe‑Loading Single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

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Nano-Micro Letters 2025年第2期17卷 187-203页

作者： Si Chen fang Huang Lijie Mao Zhimin Zhang Han Lin Qixin Yan xiangyu Lu Jianlin Shi Department of Cardiology Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200092People’s Republic of China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China Shanghai Frontiers Science Center of Nanocatalytic Medicine School of MedicineTongji UniversityShanghai 200092People’s Republic of China

The current single-atom catalysts(SACs)for medicine still suffer from the limited active site ***,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with *** constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial ***,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading ***,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/*** addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)*** in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound *** work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

关键词： Nanocatalytic medicine Single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis

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论梁启超与鲁迅对韩国文学的影响

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学术交流 2016年第8期 191-195页

作者：方香玉齐齐哈尔大学外国语学院黑龙江齐齐哈尔161000

中韩地理位置相近,中国博大精深的文化很自然地传到了韩国,不少文学作品介绍到韩国。20世纪,中韩文学的关联大幅度减弱,几近中断。在20世纪初,中韩两国都有着相似的社会背景,在西方文明的接受上基本有着相同的认识,所以当时中国的启蒙... 详细信息

中韩地理位置相近,中国博大精深的文化很自然地传到了韩国,不少文学作品介绍到韩国。20世纪,中韩文学的关联大幅度减弱,几近中断。在20世纪初,中韩两国都有着相似的社会背景,在西方文明的接受上基本有着相同的认识,所以当时中国的启蒙思想对韩国的爱国启蒙运动影响很大,使得韩国的文人开始意识到救国自强的意义,以梁启超、鲁迅为代表的文学家及其文学观对韩国开化期的小说创作影响很大,而之后韩国仍然对中国文学保持兴趣,中国现代文学的代表作被不断翻译、介绍到韩国,对韩国文学产生了积极影响。

关键词： 20世纪中国文学韩国文学影响

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Research on Improving Labor Productivity in Chinese Railway Enterprises

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Chinese Business Review 2004年第9期3卷 1-6页

作者： Qun Li xiangyu Zhao Ting fang Pingyan Wan Rui Zhang School of Economics and Management Beijing Jiaotong University Beijing P. R. China

Our research aims to summarize the implementation results of the former strategy of reducing redundant personnel and improving productivity in Chinese railway system. Based on the experience and advanced methods of foreign railway enterprises, the thesis studies the way and measures for the Chinese railway enterprises to improve the labor productivity in the new historical period and provides policy suggestions for further improving labor productivity in Chinese railway enterprises.

关键词： Chinese railway transportation enterprises labor productivity research

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A citrullinated antigenic vaccine in treatment of autoimmune arthritis

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Science Bulletin 2024年第18期69卷 2920-2929页

作者： Xu Jin Tianya Dong Qian Wang Yang Xie xiangyu fang Chaonan Wei Shuyan Liu Xi Zheng Ping Wang Danxue Zhu Lulu Cao Suwei Dong Kechi fang Chao Zhong Jing Wang Fanlei Hu Zhanguo Li Department of Rheumatology and Immunology Peking University People’s Hospital&Beijing Key Laboratory for Rheumatism Mechanism and Immune DiagnosisBeijing 100044China Peking-Tsinghua Center for Life Sciences Peking UniversityBeijing 100871China CAS Key Laboratory of Mental Health Institute of PsychologyChinese Academy of SciencesBeijing 100101China Department of Psychology University of Chinese Academy of SciencesBeijing 100049China Department of Chemical Biology School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Institute of Systems Biomedicine Department of ImmunologyNHC Key Laboratory of Medical Immunology(Peking University)Beijing Key Laboratory of Tumor Systems BiologyPeking University Health Science CenterBeijing 100191China State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Department of Integration of Chinese and Western Medicine School of Basic Medical SciencesPeking UniversityBeijing 100191China

Rheumatoid arthritis(RA)is an inflammatory autoimmune disease triggered by antigenic peptides with environmental and genetic risk *** has been shown that antigen-specific targeting could be a promising therapeutical strategy for RA by restoring immune tolerance to self-antigens without compromising normal *** of antigens enhances antigenic properties and induces autoimmune ***,we showed that citrullinated antigenic(citAg)vaccine ameliorated collageninduced arthritis with decreased T-helper 1(Th1)and Th17 cells,downregulated proinflammatory cytokines including interlukin-6 and tumor necrosis factor-a,and inhibited antigen recall responses.B cell receptor sequencing further revealed that citAg vaccine could dampen the dysregulated V(D)J recombination,restoring the immune *** together,the results demonstrated that citAg vaccine might have a therapeutic effect on RA.

关键词： CitAg Citrullination Collagen typeⅡ Therapeutic vaccine Immune tolerance Rheumatoid arthritis

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韩流文化特点初探

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黑龙江民族丛刊 2016年第2期 163-167页

作者：方香玉齐齐哈尔大学黑龙江齐齐哈尔161006

韩流文化的传播在持续不断的扩展之中,从影视剧、现代音乐舞蹈、综艺节目、网络游戏到服装配饰、食品餐饮、化妆整容等等,上述浸透着韩国文化气息的产品和生活方式,在传入中国短短20多年以来,快速、广泛地掀起流行风潮,中国媒体将这种... 详细信息

韩流文化的传播在持续不断的扩展之中,从影视剧、现代音乐舞蹈、综艺节目、网络游戏到服装配饰、食品餐饮、化妆整容等等,上述浸透着韩国文化气息的产品和生活方式,在传入中国短短20多年以来,快速、广泛地掀起流行风潮,中国媒体将这种状况称为"韩流"。韩流文化发展至今,形成了多元融合性、政府主导性、内容综合性、大众消费性、前卫时尚性、影响国际性等独特的特点。

关键词：韩流文化传播特点影响

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齐齐哈尔与韩国光州饮食文化特色

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四川烹饪高等专科学校学报 2008年第3期 14-16页

作者：方香玉齐齐哈尔大学外语学院黑龙江齐齐哈尔161006

本论文通过对中国齐齐哈尔市和韩国光州的饮食文化的比较,研究两国两市饮食文化在各国以及世界的影响。通过对两国两市的饮食特点进行描述,列举各自特点,将两国两市具有的不同食品文化进行分析比较,为增进双方在文化上的了解提供参考和... 详细信息

本论文通过对中国齐齐哈尔市和韩国光州的饮食文化的比较,研究两国两市饮食文化在各国以及世界的影响。通过对两国两市的饮食特点进行描述,列举各自特点,将两国两市具有的不同食品文化进行分析比较,为增进双方在文化上的了解提供参考和依据。

关键词：齐齐哈尔韩国光州饮食文化特色

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电梯曳引钢带摩擦系数测量方法

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中国电梯 2022年第3期33卷 28-30页

作者：房祥雨沈阳远大智能工业集团股份有限公司沈阳110027

与钢丝绳相比,曳引钢带是一种新型的传动媒介,多数电梯厂家对曳引钢带摩擦系数的测量还不太熟悉。对此,介绍了一种在整梯状态下可以测量曳引钢带摩擦系数的方法,包括如何使用工装测出曳引钢带的动摩擦力和静摩擦力,以及细砂介质测量方... 详细信息

与钢丝绳相比,曳引钢带是一种新型的传动媒介,多数电梯厂家对曳引钢带摩擦系数的测量还不太熟悉。对此,介绍了一种在整梯状态下可以测量曳引钢带摩擦系数的方法,包括如何使用工装测出曳引钢带的动摩擦力和静摩擦力,以及细砂介质测量方法、水介质测量方法、油介质测量方法等。最后介绍了具体测试过程。

关键词：电梯曳引钢带摩擦系数测量方法滞留工况

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一则家用电梯急停测试案例的分析

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中国电梯 2021年第4期32卷 57-59页

作者：房祥雨沈阳远大智能工业集团股份有限公司沈阳110027

1家用电梯在急停时出现的问题近期,笔者正测试一款家用电梯,电梯速度为0.4m/s,额定载重为400kg。在空载上行时按急停后,发现大约有一半的概率安全回路会断开。经排查,发现为限速器动作。GB/T 21739-2008《家用电梯制造与安装规范》中的... 详细信息

1家用电梯在急停时出现的问题近期,笔者正测试一款家用电梯,电梯速度为0.4m/s,额定载重为400kg。在空载上行时按急停后,发现大约有一半的概率安全回路会断开。经排查,发现为限速器动作。GB/T 21739-2008《家用电梯制造与安装规范》中的第10.***.1.5条规定:限速器应在轿厢速度大于等于额定速度的115%且小于0.63m/s时动作。

关键词：额定速度限速器安全回路家用电梯轿厢额定载重电梯速度 GB/T

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