检索结果-南通市图书馆

Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi Xu Junqiu Jia Rui Mao xiang Cao yun Xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Investigation of bubbles escape behavior from low basicity mold flux for high-Mn high-Al steels using 3D X-ray microscope

引用

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 102-110页

作者： Qiang Liu xiang Li Shen Du Ming Gao Yanbin Yin Jiongming Zhang State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

During the continuous casting process of high-Mn high-Al steels,various types of gases such as Ar need to escape through the top of the *** which,the behavior of bubbles traversing the liquid slag serves as a restrictive link,closely associated with viscosity and the thickness of liquid *** contrast to two-dimensional surface observation,three-dimensional(3D)analysis method can offer a more intuitive,accurate,and comprehensive ***,this study employs a 3D X-ray microscope(3D-XRM)to obtained spatial distribution and 3D morphological characteristics of residual bubbles in mold flux under different basicity of liquid slag,different temperatures,and different holding *** results indicate that as basicity of slag increases from 0.52 to 1.03,temperature increases from 1423 to 1573 K,the viscosity of slag decreases,the floating rate of bubbles *** addition,when holding time increases from 10 to 30 s,the bubbles floating distance increases,and the volume fraction and average equivalent sphere diameter of the bubbles solidified in the mold flux gradually *** one word,increasing the basicity,temperature,and holding time leading to an increase in the removal rate of bubbles especially for the *** findings of bubbles escape behavior provide valuable insights into optimizing low basicity mold flux for high-Mn high-Al steels.

关键词： mold flux low basicity bubbles three-dimensional X-ray microscope viscosity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Polarization-encoded neural networks with simplified grating patch

引用

Science China Technological Sciences 2025年

作者： Chengyan ZHONG xiang WANG Lingfei LI yuanchi CUI Lei XIAO Dawei SONG Junxiong GUO Wen HUANG yufeng GUO yu LIU College of Integrated Circuit Science and Engineering Nanjing University of Posts and Telecommunications National and Local Joint Engineering Laboratory of RF Integration and Micro-Assembly Technology College of Integrated Circuits hangzhou Global Scientific and Technological Innovation Centre Zhejiang University Nanjing Mumusili Technology Co. LTD School of Integrated Circuits Tsinghua University Institute of Advanced Study School of Electronic Information and Electrical Engineering Chengdu University State Key Laboratory of Electronic Thin Films and Integrated Devices School of Integrated Circuit Science and EngineeringUniversity of Electronic Science and Technology of China

Optical neural networks (ONNs) offer a promising solution for high-performance, energy-efficient artificial intelligence hardware by leveraging the parallelism and speed of light. However, the large-scale implementation of ONNs remains challenging due to the bulky footprint and complex control of optical synapses. In this work, we propose and simulate a plasmonic polarized synaptic architecture that overcomes the diffraction limit and enables ultra-compact ONNs. By tuning the polarization state of incident light, the optical transmittance through each plasmonic unit can be dynamically adjusted to represent a synaptic weight. Our plasmonic structures, with features as small as 40 nm, operate well below this limit in the visible spectrum (400–750 nm). Compared with diffraction and interference-based circuit designs, our proposed method achieves a substantial reduction in synaptic density by factors of 150000-fold and 1500-fold, respectively. Furthermore, we successfully demonstrate a proof-of-concept plasmonic ONN applied to the Canadian Institute for Advanced Research—10classes (CIFAR-10) dataset using a Visual Geometry Group network with 16 layers (VGG16) model. After training for 80epochs, the network achieves an accuracy of 93%. The polarization-tunable plasmonics paves the way towards scalable ONNs for next-generation artificial intelligence (AI) accelerators and smart sensors.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Improvement of Cold Recycled Mixture Performance Based on Improved Density Test Method and RAP Characteristics

引用

Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 79-87页

作者： han Zhanchuang PANG Yafeng LIN Hongwei China First Highway Engineering Group Co. LtdBeijing 100024China The Key Laboratory of Road and Traffic Engineering Ministry of EducationTongji UniversityShanghai 201804China Guangzhou Baiyun International Airport Co. Ltd.Guangzhou 510470China

The available test methods for optimal moisture content of cold recycled mixture(CRM)as well as its bulk specific gravity,and theoretical maximum relative density were analyzed in this *** test improvements were suggested to improve test control of the CRM road performance based on the discovered ***,the properties of reclaimed asphalt pavement(RAP),including the content of old asphalt,penetration index,passing rate of 4.75 mm sieve,and gradation change rate after extraction,were *** effects of RAP characteristics on splitting tensile strength,water stability,the high-and low-temperature performance of emulsified asphalt CRM were *** results show that the optimum moisture content of CRM should be determined when the compaction work matches the specimen’s molding *** the analyzed methods of bulk specific gravity assessment,the dry-surface and CoreLok methods provide more robust and accurate results than the wax-sealing method,while the dry-surface method is the most *** modified theoretical maximum relative density test method is proposed,which can reduce the systematic error of the vacuum test *** following RAP-CRM trends can be *** lower the content of old asphalt and the smaller the change rate of gradation,the smaller the voids and the better the water stability of *** greater the penetration of old asphalt,the higher the fracture work and low-temperature splitting *** greater the penetration,the higher the passing rate of 4.75 mm sieve after extraction,and the worse the high-temperature performance of CRM.

关键词： RAP volume parameters high-temperature performance low-temperature performance water stability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

引用

Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang Chung Hsien Wu Jiwen Jiang Fei Long Liyuan han Qifeng han Yi‑Bing Cheng Yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Silk damping in scalar-induced gravitational waves: a novel probe for new physics

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 79-85页

作者： Yan-Heng yu Sai Wang Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences School of Physics University of Chinese Academy of Sciences

Silk damping is well known in the study of cosmic microwave background（CMB） and accounts for suppression of the angular power spectrum of CMB on large angular multipoles. In this article, we study the effect of Silk damping on the scalar-induced gravitational waves（SIGWs）. Resulting from the dissipation of cosmic fluid, the Silk damping notably suppresses the energydensity spectrum of SIGWs on scales comparable to a diffusion scale at the decoupling time of weakly-interacting particles. The effect offers a novel observable for probing the underlying particle interaction, especially for those mediated by heavy gauge bosons beyond the standard model of particles. We anticipate that pulsar timing arrays are sensitive to gauge bosons with mass ～10～3-10～4 GeV, while space-and ground-based interferometers to those with mass ～10～7-1012GeV, leading to essential complements to on-going and future experiments of high-energy physics.

关键词： scalar-induced gravitational waves Silk damping new physics

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

170例儿童眼内异物患者的致病原因、临床特征及预后分析

引用

眼科 2018年第2期27卷 150-154页

作者：李林史翔宇韩崧刘毅周军刘宁朴卢海首都医科大学附属北京同仁医院北京同仁眼科中心眼科学与视觉科学北京市重点实验室 100730

目的研究儿童眼内异物患者的致病原因、临床特征及预防策略。设计回顾性病例系列。研究对象北京同仁医院2004年1月至2016年12月因眼内异物住院的14岁及以下儿童患者170例。年龄1~14岁,平均(8.73±3.12)岁。其中男性157例(92.4%)。方法... 详细信息

目的研究儿童眼内异物患者的致病原因、临床特征及预防策略。设计回顾性病例系列。研究对象北京同仁医院2004年1月至2016年12月因眼内异物住院的14岁及以下儿童患者170例。年龄1~14岁,平均(8.73±3.12)岁。其中男性157例(92.4%)。方法收集及分析患者的基本信息、致伤原因、致伤物、眼部并发症、眼内异物特征、手术治疗情况及预后。主要指标致病原因、致伤物种类、并发症和致盲率。结果致伤原因中爆炸伤占首位(59.4%,n=101),其次是锐器扎伤(20.6%,n=35)。常见的致伤物是烟花爆竹(41.2%,n=70)及雷管(8.8%,n=15)。并发眼内炎35例(25.0%),视网膜裂孔或脱离96例(56.5%)。140例(82.4%)患者的异物位于眼后节。148例(87.1%)施行玻璃体切除术。105例(61.8%)术后患眼矫正视力低于0.05。爆炸伤患者术后患眼盲的比例高于其他类致伤原因的患者(72.3%及46.4%,P<0.01)。结论儿童眼内异物伤的首要致伤原因是爆炸伤,烟花爆竹是首要致伤物。多数患者视力预后不佳。

关键词：儿童眼内异物病因

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

清痰合剂对小鼠气管分泌物影响的实验研究

引用

湖南中医杂志 2018年第3期34卷 152-153页

作者：李向宇马涵涛河南科技大学第一附属医院河南洛阳471003

目的:通过研究清痰合剂对实验小鼠气管分泌物的影响,探讨清痰合剂的祛痰作用及对急性气管-支气管炎与慢性支气管炎急性发作期的作用机制。方法:将50只昆明种小鼠随机均分为5组:0.9%氯化钠注射液组、盐酸氨溴索片组及大、中、小剂量清痰... 详细信息

目的:通过研究清痰合剂对实验小鼠气管分泌物的影响,探讨清痰合剂的祛痰作用及对急性气管-支气管炎与慢性支气管炎急性发作期的作用机制。方法:将50只昆明种小鼠随机均分为5组:0.9%氯化钠注射液组、盐酸氨溴索片组及大、中、小剂量清痰合剂组,连续灌胃给药5d,于末次给药后1h腹腔注射酚红溶液,处死小鼠,取下相同位置的一段气管并冲洗,测洗出液的吸光度,计算气管冲洗液中的酚红浓度。结果:与0.9%氯化钠注射液组比较,大、中、小剂量清痰合剂组及盐酸氨溴索片组气管洗出液的吸光度均明显增高,差异具有统计学意义(P<0.01),说明大、中、小剂量清痰合剂组及盐酸氨溴索片组均可显著促进小鼠气管分泌。结论:清痰合剂可显著促进小鼠气管的分泌,增高气管洗出液的吸光度,表明清痰合剂有很好的祛痰作用。

关键词：清痰合剂气管分泌物小鼠实验研究

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unmasking Social Robots’Camouflage:A GNN-Random Forest Framework for Enhanced Detection

引用

Computers, Materials & Continua 2025年第1期82卷 467-483页

作者： Weijian Fan Chunhua Wang Xiao han Chichen Lin School of Data Science and Intelligent Media Communication University of ChinaBeijing100024China School of Computer and Cyber Sciences Communication University of ChinaBeijing100024China Institute of Communication Studies Communication University of ChinaBeijing100024China State Key Laboratory of Media Convergence and Communication Communication University of ChinaBeijing100024China

The proliferation of robot accounts on social media platforms has posed a significant negative impact,necessitating robust measures to counter network anomalies and safeguard content *** robot detection has emerged as a pivotal yet intricate task,aimed at mitigating the dissemination of misleading *** graphbased approaches have attained remarkable performance in this realm,they grapple with a fundamental limitation:the homogeneity assumption in graph convolution allows social robots to stealthily evade detection by mingling with genuine human *** unravel this challenge and thwart the camouflage tactics,this work proposed an innovative social robot detection framework based on enhanced HOmogeneity and Random Forest(HORFBot).At the core of HORFBot lies a homogeneous graph enhancement strategy,intricately woven with edge-removal techniques,tometiculously dissect the graph intomultiple revealing ***,leveraging the power of contrastive learning,the proposed methodology meticulously trains multiple graph convolutional networks,each honed to discern nuances within these tailored *** culminating stage involves the fusion of these feature-rich base classifiers,harmoniously aggregating their insights to produce a comprehensive detection *** experiments on three social robot detection datasets have shown that this method effectively improves the accuracy of social robot detection and outperforms comparative methods.

关键词： Social robot detection graph neural networks random forest homophily heterophily

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

引用

Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi yu Faith Teo En Ning Chang Liu yu-Chi Liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：