检索结果-南通市图书馆

Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor-and Cygb-associated signaling pathways

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2706-2726页

作者： Biao Xiao Chaoyang Chu Zhicheng Lin Tianyuan Fang Yuyu zhou Chuxia Zhang Jianghui Shan Shiyu Chen Liping Li Department of Physiology and Pharmacology Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Ningbo Key Laboratory of Behavioral Neuroscience Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Key Laboratory of Addiction Research of Zhejiang Province NingboZhejiang ProvinceChina

A reduction in adult neurogenesis is associated with behavioral abnormalities in patients with Alzheimer's ***,enhancing adult neurogenesis represents a promising therapeutic approach for mitigating disease symptoms and ***,nonpharmacological interventions aimed at inducing adult neurogenesis are currently *** individual non-pharmacological interventions,such as aerobic exercise,acousto-optic stimulation,and olfactory stimulation,have shown limited capacity to improve neurogenesis and cognitive function in patients with Alzheimer's disease,the therapeutic effect of a strategy that combines these interventions has not been fully *** this study,we observed an age-dependent decrease in adult neurogenesis and a concurrent increase in amyloid-beta accumulation in the hippocampus of amyloid precursor protein/presenilin 1 mice aged 2-8 *** deposition became evident at 4 months,while neurogenesis declined by 6 months,further deteriorating as the disease ***,following a 4-week multifactor stimulation protocol,which encompassed treadmill running(46 min/d,10 m/min,6 days per week),40 Hz acousto-optic stimulation(1 hour/day,6 days/week),and olfactory stimulation(1 hour/day,6 days/week),we found a significant increase in the number of newborn cells(5'-bromo-2'-deoxyuridine-positive cells),immature neurons(doublecortin-positive cells),newborn immature neurons(5'-bromo-2'-deoxyuridine-positive/doublecortin-positive cells),and newborn astrocytes(5'-bromo-2'-deoxyuridine-positive/glial fibrillary acidic protein-positive cells).Additionally,the amyloid-beta load in the hippocampus *** findings suggest that multifactor stimulation can enhance adult hippocampal neurogenesis and mitigate amyloid-beta neuropathology in amyloid precursor protein/presenilin 1 ***,cognitive abilities were improved,and depressive symptoms were alleviated in amyloid precursor protein/presenilin 1 mice

关键词： acousto-optic stimulation adult neurogenesis Alzheimer's disease amyloid precursor protein/presenilin 1 mice amyloid-beta deposition brain cell apoptosis cognitive impairment depression-like behavior involuntary treadmill exercise olfactory stimulation serum metabolites

Review of precipitation strengthening in ultrahigh-strength martensitic steel

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 256-269页

作者： Zhihao Tian Chunlei Shang Chaolei Zhang Xiaoye zhou Honghui Wu Shuize Wang Guilin Wu Junheng Gao Jiaming Zhu Xinping Mao Institute for Carbon Neutrality University of Science and Technology BeijingBeijing 100083China Institute of Steel Sustainable Technology Liaoning Academy of MaterialsShenyang 110004China Department of Materials Science and Engineering Shenzhen MSU-BIT UniversityShenzhen 518172China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China School of Civil Engineering Shandong UniversityJinan 250061China

Martensite is an important microstructure in ultrahigh-strength steels,and enhancing the strength of martensitic steels often involves the introduction of precipitated phases within the martensitic *** considerable research efforts devoted to this area,a systematic summary of these advancements is *** review focuses on the precipitates prevalent in ultrahigh-strength martensitic steel,primarily carbides(e.g.,MC,M_(2)C,and M_(3)C)and intermetallic compounds(e.g.,Ni Al,Ni_(3)X,and Fe_(2)Mo).The precipitation-strengthening effect of these precipitates on ultrahigh-strength martensitic steel is discussed from the aspects of heat treatment processes,microstructure of precipitate-strengthened martensite matrix,and mechanical ***,a perspective on the development of precipitation-strengthened martensitic steel is presented to contribute to the advancement of ultrahigh-strength martensitic *** review highlights significant findings,ongoing challenges,and opportunities in the development of ultrahigh-strength martensitic steel.

关键词： ultrahigh-strength martensitic steel precipitation strengthening mechanical property carbide intermetallic compound

A generalized Liouville's formula

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics(A Journal of Chinese Universities) 2022年第3期37卷 470-474页

作者： MA wen-Xiu YONG Xue-lin QIN Zhen-yun GU xiang zhou Yuan Department of Mathematics Zhejiang Normal UniversityJinhua 321004China Department of Mathematics King Abdulaziz UniversityJeddah 21589Saudi Arabia Department of Mathematics and Statistics University of South FloridaTampaFL 33620-5700USA School of Mathematical and Statistical Sciences North-West UniversityMafikeng CampusSouth Africa School of Mathematics and Physics North China Electric Power UniversityBeijing 102206China School of Mathematics and Key Lab for Nonlinear Mathematical Models and Methods Fudan UniversityShanghai 200433China School of Business Xianda College of Economics&HumanitiesShanghai International Studies UniversityShanghai 200083China

A generalized Liouville’s formula is established for linear matrix differential equations involving left and right *** special cases are used to determine the localness of characteristics of symmetries and solutions ... 详细信息

关键词： Liouville’s formula soliton hierarchy Riemann-Hilbert problem

Risk assessment and landslide prevention design using numerical modelling——A case study in Qingliu,China

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2023年第4期20卷 943-961页

作者： LI Cong-jiang HU Yu-xiang JIANG Nan LI Hai-bo zhou Jia-wen State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan UniversityChengdu610065China College of Water Resource and Hydropower Sichuan UniversityChengdu610065China

Numerous Quaternary deposits are existed in the mountainous areas of Southwest China,especially in the transition zone between the QinghaiTibet Plateau and the Sichuan Basin,where strong tectonic movements and frequent climatic changes increase the potential *** possible deformation and failure process of potential landslides and their impacts on the surrounding environment are important research *** investigation and monitoring indicate that the Qingliu landslide in Xiameng town,Li County,Sichuan Province,China has been continuously deforming since August *** deformation zone has a maximum deformation depth of approximately 18.9m,a total area of 54,628 m2,and a volume of 34.0×104 m3,which seriously threatens infrastructure projects and *** a result,understanding the Qingliu landslide evolution process,assessing the hazard risk,and planning disaster prevention measures are of great significance for reducing disaster *** this study,the mass movement process and hazard risk of the Qingliu landslide are evaluated,and the effects of different prevention measures are compared and *** using the depth-integrated method,the mass movement of the Qingliu landslide is *** numerical simulation results indicate that the maximum velocity of the Qingliu landslide is approximately 37.5 m/s,and the duration of the landslide is approximately *** simulated landslide can eventually form a deposited mass with a maximum deposit thickness of 19.4 m and an area of approximately 60,168.3 m2,thereby blocking the river and burying ***,a risk assessment of the Qingliu landslide under different forms of protection measures is also produced and discussed by considering the hazard level and economic vulnerability level of the affected *** three layers of anti-slide piles on the deformation zone to reduce the hazard risk of the Qingliu landslide is a better *** results may be useful for planning preventio

关键词： Qingliu landslide Numerical simulation Mass movement Risk assessment Prevention measures

Semi-interpenetrating-network all-solid-state polymer electrolyte with liquid crystal constructing efficient ion transport channels for flexible solid lithium-metal batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2022年第4期31卷 157-167页

作者： Qinghui Zeng Yu Lu Pingping Chen Zhenfeng Li Xin wen wen wen Yu Liu Shuping Zhang Hailei Zhao Henghui zhou Zhi-xiang Wang Liaoyun Zhang School of Chemical Sciences University of Chinese Academy of SciencesBeijing 100049China College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871China School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Pulead Technology Industry Co. LtdBeijing 102200China

The development of the solid-state polymer electrolytes (SPEs) for Li-ion batteries (LIBs) can effectively address the hidden safety issues of commercially used liquid ***,the unsatisfactory room temperature ion conductivity and inferior mechanical strength for linear PEO-based SPEs are still the immense obstacles impeding the further applications of SPEs for large-scale ***,we fabricate a series of semi-interpenetrating-network (semi-IPN) polymer electrolytes based on a novel liquid crystal (C6M LC) and poly(ethylene glycol) diglycidyl ether (PEGDE) via UV-irradiation at the first *** LCs not only highly improve the mechanical properties of electrolyte membranes via the construction of network structure with PEGDE,but also create stable ion transport channels for ion *** a result,a free-standing flexible SPE shows outstanding ionic conductivity(5.93×10^(-5) S cm^(-1) at 30℃),a very wide electrochemical stability window of 5.5 V,and excellent thermal stability at thermal decomposition temperatures above 360℃ as well as the capacity of suppressing lithium dendrite ***,the LiFePO_(4)/Li battery assembled with the semi-IPN electrolyte membranes exhibits good cycle performance and admirable reversible specific *** work highlights the obvious advantages of LCs applied to the electrolyte for the advanced solid lithium battery.

关键词： Solid-state polymer electrolyte Liquid crystal Semi-interpenetrating-network Ion transport channels Lithium battery

浒苔在对虾养殖尾水中生长特性及其对氮磷去除效果的初步研究

在线全文

学校读者我要写书评

暂无评论

宁波大学学报（理工版） 2018年第5期31卷 18-23页

作者：吴嘉仪戚静杰向文洲王佳莹郑诚王政杨文郑忠明宁波大学海洋学院浙江宁波315211 中国科学院南海海洋研究所广东广州510301

研究了不同温度下浒苔在对虾养殖尾水中的生长及其对N、P营养盐去除效果的影响.实验设置了3个温度梯度组(15、20、25℃),每个温度以自然海水(SW)及f/2海水培养基(F/2)为对照组,对虾养殖尾水(WW)为处理组,隔天测定各组中浒苔的生长状况... 详细信息

研究了不同温度下浒苔在对虾养殖尾水中的生长及其对N、P营养盐去除效果的影响.实验设置了3个温度梯度组(15、20、25℃),每个温度以自然海水(SW)及f/2海水培养基(F/2)为对照组,对虾养殖尾水(WW)为处理组,隔天测定各组中浒苔的生长状况及尾水组中N、P营养盐含量的变化.结果显示,浒苔在WW组中生长较SW组好,差异显著;而与F/2组相比无显著性差异.20℃下浒苔生长最适宜,特定生长率达34.80%·d-1.各组中NH4+最大去除率在温度为15、20、25℃时分别为96.91%、97.21%、98.18%;NO2-和NO3-的去除率均大于99%;PO43-和TP去除率在25℃时达到最大,分别为97.87%、90.10%;表明温度对浒苔生长及其吸收WW中N、P营养盐有一定影响.

关键词：浒苔海水养殖尾水生长营养盐

Photocatalytic and photochemical processes of AgCl/TiO_(2) studied with a fully integrated X-ray photoelectron spectrometer

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2021年第4期40卷 799-807页

作者： Kai zhou wen-Lu He Xiao Zhang Bin Zhang xiang-Nan Gong Kai-wen Wang Zhi-Chao Zhang Xi-Lan Zhang Zhi-Ning Xia Xiao-Yuan zhou Analytical and Testing Center Chongqing UniversityChongqing 401331China College of Physics Chongqing UniversityChongqing 401331China Beijing Key Laboratory and Institute of Microstructure and Property of Advanced Materials Beijing University of TechnologyBeijing 100124China School of Materials Science and Engineering Chongqing UniversityChongqing 400045China

A fully integrated X-ray photoelectron spectrometer(XPS) was employed for the investigation of the separation processes and recombination behaviors of photogenerated electrons and holes on the surface of AgCl and ultra-small nano-titanium oxide cluster composite photocatalyst(AgCl/TiO_(2)).A facile route,by direct colloidal synthesis,for preparing AgCl/TiO_(2)with high stability and enhanced visible light(Vis) driven catalytic activity was *** photocatalytic activity of AgCl/TiO_(2),which revealed that the photo-degradation rate of the as-prepared AgCl/TiO_(2)was nearly 10.5 times higher than that of bare AgCl,was evaluated by applying it to the photo-degradation of methyl orange(MO) in water ***,AgCl/TiO_(2)exhibited an outstanding long-term stability during ten cycles of *** band gap of AgCl decreased from 3.25 to 2.85 eV because of the ultrasmall nano-TiO_(2)clusters that were pinned to its *** results indicate that the band gap narrowing and surface plasmon resonance(SPR) of Ag(0) were two major contributors to the enhancement of the photocatalytic activity of AgCl/TiO_(2)by improving the utilization of *** situ XPS analysis was,therefore,certified as a beneficial method to explore the catalytic mechanism of photocatalysts.

关键词： Photocatalysis AgCl/TiO_(2) Fully integrated XPS Band gap narrowing

QuEChERS结合HPLC检测辣椒及其制品中天然辣椒素、二氢辣椒素和合成辣椒素

在线全文

学校读者我要写书评

暂无评论

食品科学 2025年第2期46卷 240-247页

作者：成璐瑶温雅君石文婷周子莹马丽艳中国农业大学食品科学与营养工程学院北京100083 北京市农产品质量安全中心北京100029 农业农村部农产品质量检验测试中心(北京) 北京100083

建立一种QuEChERS结合高效液相色谱快速检测辣椒及其制品中的天然辣椒素、二氢辣椒素和合成辣椒素的方法。样品用乙腈提取,无水硫酸镁、十八烷基硅烷(C18)、乙二胺-N-丙基硅烷化硅胶、石墨化炭黑复合吸附剂净化。采用Agilent Eclipse Pl... 详细信息

建立一种QuEChERS结合高效液相色谱快速检测辣椒及其制品中的天然辣椒素、二氢辣椒素和合成辣椒素的方法。样品用乙腈提取,无水硫酸镁、十八烷基硅烷(C18)、乙二胺-N-丙基硅烷化硅胶、石墨化炭黑复合吸附剂净化。采用Agilent Eclipse Plus C18(150 mm×4.6 mm,5μm)分离,以0.4%磷酸水溶液和90%乙腈溶液为流动相进行梯度洗脱,荧光检测器进行检测。结果表明:天然辣椒素、二氢辣椒素和合成辣椒素在0.20~100 mg/L范围内线性关系良好,决定系数(R2)均大于0.999。天然辣椒素的方法检出限为0.014~0.069 mg/kg,定量限为0.046~0.23 mg/kg;二氢辣椒素的方法检出限为0.023~0.12 mg/kg,定量限为0.077~0.39 mg/kg;合成辣椒素的方法检出限为0.018~0.088 mg/kg,定量限为0.059~0.30 mg/kg。在干辣椒、鲜辣椒、香菇酱、辣椒油4种基质中,3个不同添加水平下的加标回收率为91.6%~117.2%,相对标准偏差为0.2%~6.1%。该方法简便、准确,不仅适用于干、鲜辣椒,而且适用于高油、高蛋白等辣椒制品中天然辣椒素、二氢辣椒素和合成辣椒素含量的检测。

关键词： QuEChERS 高效液相色谱辣椒辣椒素合成辣椒素

Preliminary safety analysis for heavy water-moderated molten salt reactor

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第6期35卷 202-217页

作者： Gao-Ang wen Jian-Hui Wu Chun-Yan Zou xiang-zhou Cai Jin-Gen Chen Man Bao College of Science University of Shanghai for Science and TechnologyShanghai 200093China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China

The heavy water-moderated molten salt reactor(HWMSR)is a newly proposed reactor concept,in which heavy water is adopted as the moderator and molten salt dissolved with fissile and fertile elements is used as the *** arising from graphite in traditional molten salt reactors,including the positive temperature coefficient and management of highly radio-active spent graphite waste,can be addressed using the *** now,research on the HWMSR has been centered on the core design and nuclear fuel cycle to explore the viability of the HWMSR and its advantages in fuel ***,the core safety of the HWMSR has not been extensively ***,we evaluate typical accidents in a small modular HWMSR,including fuel salt inlet temperature overcooling and overheating accidents,fuel salt inlet flow rate decrease,heavy water inlet temperature overcooling accidents,and heavy water inlet mass flow rate decrease accidents,based on a neutronics and thermal-hydraulics coupled *** results demonstrated that the core maintained safety during the investigated accidents.

关键词： Heavy water-moderated molten salt reactor Neutronics and thermal-hydraulics coupling Transient analysis Accident analysis