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Strip deep rotary tillage combined with controlled-release urea improves the grain yield and nitrogen use efficiency of maize in the North China Plain

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Journal of Integrative Agriculture 2022年第9期21卷 2559-2576页

作者： HAN Yu-ling GUO Dong MA wei GE Jun-zhu LI xiang-ling Ali Noor MEHMOOD ZHAO Ming ZHou Bao-yuan Institute of Crop Sciences Chinese Academy of Agricultural Sciences/Key Laboratory of Crop Physiology and EcologyMinistry of Agriculture and Rural AffairsBeijing 100081P.R.China College of Agriculture Northeast Agricultural UniversityHarbin 150030P.R.China College of Agronomy&Resource and Environment Tianjin Agricultural UniversityTianjin 300384P.R.China College of Agronomy and Biotechnology Hebei Normal University of Science&TechnologyQinhuangdao 066004P.R.China

Inappropriate tillage practices and nitrogen(N) management have become seriously limitations for maize(Zea mays L.) yield and N use efficiency(NUE) in the North China Plain(NCP). In the current study, we examined the effects of strip deep rotary tillage(ST) combined with controlled-release(CR) urea on maize yield and NUE, and determined the physiological factors involved in yield formation and N accumulation during a 2-year field experiment. Compared with conventional rotary tillage(RT) and no-tillage(NT), ST increased the soil water content and soil mineral N content(Nmin) in the 20–40 cm soil layer due to reduction by 10.5 and 13.7% in the soil bulk density in the 0–40 cm soil layer, respectively. Compared with the values obtained by common urea(CU) fertilization, CR increased the Nmin in the 0–40 cm soil layers by 12.4 and 10.3% at the silking and maturity stages, respectively. As a result, root length and total N accumulation were enhanced under ST and CR urea, which promoted greater leaf area and dry matter(particularly at post-silking), eventually increasing the1 000-kernel weight of maize. Thus, ST increased the maize yield by 8.3 and 11.0% compared with RT and NT, respectively, whereas CR urea increased maize yield by 8.9% above the values obtained under CU. Because of greater grain yield and N accumulation, ST combined with CR urea improved the NUE substantially. These results show that ST coupled with CR urea is an effective practice to further increase maize yield and NUE by improving soil properties and N supply, so it should be considered for sustainable maize production in the NCP(and other similar areas worldwide).

关键词： maize strip deep rotary tillage controlled-release urea nitrogen accumulation grain yield

Short-term observation of direct oral anticoagulant use in an atrial fibrillation patient with high bleeding risk and kidney transplant:a case report

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Journal of Geriatric Cardiology 2021年第8期18卷 692-696页

作者： wei xiang ling-Yun KONG Jing BAI Jun-Jie XIE Fang LIU Department of Cardiology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijingChina Department of Organ Transplant Center Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijingChina

Kidney transplant(KTx)is considered to be the best treatment for end-stage renal diseases compared with hemodialysis or peritoneal dialysis,because it significantly im-proves renal function,reduces cardiovascular events and mortality,enhances quality of life and prolongs life expectancy.[1,2]Atrial fibrillation(AF)is frequently coexistent with KTx,and a higher risk will occur in KTx recipients with AF compared with those aren’t with AF.[3]Patients with AF are at risk of stroke,systemic emboli and *** is recom-mended that high-risk AF patients should use oral anticoagulants for preventive *** oral anticoagulants(DOACs),including dabigatran,rivaroxaban,apixaban and edoxaban,are widely recommended for use in the general population compared to vitamin K antagonists(VKA).

关键词： fibrillation dialysis Kidney

POLYBINAPHTHYLS INCORPORATING (R)-2,2'-BINAPHTHO-20-CROWN-6 AND NAPHTHYL MOITIES

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Chinese Journal of Polymer Science 2006年第6期24卷 619-625页

作者： Dan Zhu Yi-xiang Cheng Xiao-wei Zou ling-wu Chen Jin-feng Song Zhi-liu Wang College of Chemistry and Chemical Engineering Nanjing University Nanjing 210093 China

Chiral polymer was synthesized by the polymerization of （R）-6,6＇-bistributylstannyl-2,2＇-binaphtho-20-crown-6 （M-1） with 1,4-dibromo-2,3-bisbutoxy-naphthyl （M-2） by Pd（PPhs）4 catalyzed Stille coupling reaction. Both monomer and polymer were analyzed by NMR, MS, FT-IR, UV, polarimetry, DSC-TGA, CD, fluorescent spectroscopy and GPC. The major difference between monomer and polymer is that a long wavelength Cotton Effect was observed for the polymer due to its more extended conjugation in the repeating unit and a highly rigid backbone in the polymer chain. Polymer has strong blue fluorescence due to the efficient energy migration from the extended n-electronic structure of the repeating unit of the polymer to the chiral binaphthyl core and is expected to have potential application in the materials of fluorescent sensors and chiral chromatographic packing for resolution ofracemic amino acid.

关键词： (R)-2,2'-Binaphtho-20-crown-6 Chiral polymer Fluorescence Stille reaction.

Forehead sEMG signal based HMI for hands-free control

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The Journal of China Universities of Posts and Telecommunications 2014年第3期21卷 98-105页

作者： ZHANG Yi ZHU xiang DAI ling-ling LUO Yuan National Engineering Research and Development Center for Information Accessibility Chongqing University of Posts and Telecommunications

A hands-free method is proposed to control an electric powered wheelchair （EPW） based on surface electromyography （sEMG） signals. A CyberLink device is deployed to obtain and analyze forehead sEMG signals generated by the facial movements. The autoregressive （AR） model is used to extract sEMG features. Then, the back-propagation artificial neural network （BPANN） is proposed to recognize different facial movement patterns and improved by Bayesian regularization and Levenberg-Marquardt （LM） algorithm. A sEMG based human-machine interface （HMI） is designed to map facial movement patterns into corresponding control commands. The experimental results show that the method is simple, real-time and have a high recognition rate.

关键词： intelligent wheelchair sEMG HMI AR model BP artificial neural network

Field released transgenic papaya effect on soil microbial communities and enzyme activities

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Journal of Environmental Sciences 2006年第4期18卷 734-740页

作者： wei xiang-dong ZOU Hui-ling CHU Lee-min LIAO Bin YE Chang-min LAN Chong-yu School of Life Sciences Sun Yat-sen University Guangzhou 510275 China Department of Biology The Chinese University ofHong Kong Shatin Hong Kong China

Soil properties, microbial communities and enzyme activities were studied in soil amended with replicase （RP）-transgenic or non-transgenic papaya under field conditions. Compared with non-transgenic papaya, significant differences （P〈0.05） were observed in total nitrogen in soils grown with transgenic papaya. There were also significant differences （P〈0.05） in the total number of colony forming units （CFUs） of bacteria, actinomycetes and fungi between soils amended with RP-transgenic plants and non-transgenic plants. Compared with non-transgenic papaya, the total CFUs of bacteria, actinomycetes and fungi in soil with transgenic papaya increased by 0.43-1.1, 0.21-0.80 and 0.46-0.73 times respectively. Significantly higher （P〈0.05） CFUs of bacteria, actinomycetes and fungi resistant to kanamycin （Km） were obtained in soils with RP-transgenic papaya than those with non-transgenic papaya in all concentrations of Km. Higher resistance quotients for Km＇（kanamycin resistant） bacteria, actinomycetes and fungi were found in soil planted with RP-transgenic papaya, and the resistance quotients for Km＇ bacteria, actinomycetes and fungi in soils with transgenic papaya increased 1.6-4.46, 0.63-2.5 and 0.75-2.30 times. RP-transgenic papaya and non-transgenic papaya produced significantly different enzyme activities in arylsulfatase （5.4-5.9x）, polyphenol oxidase （0.7-1.4x）, invertase （0.5-0.79x）, cellulase （0.23-0.35x） and phosphodiesterase （0.16-0.2x）. The former three soil enzymes appeared to be more sensitive to the transgenic papaya than the others, and could be useful parameters in assessing the effects of transgenic papaya. Transgenic papaya could alter soil chemical properties, enzyme activities and microbial communities.

关键词： transgenic papaya soil microbes enzyme activity kanamycin resistance resistance quotient

Measurement of two-phase velocities in bubble flows using laser Doppler velocimetry

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Journal of Hydrodynamics 2022年第6期34卷 1134-1144页

作者： ling-xin Zhang Xin-sheng Cheng Han Tu Qi Gao Xue-ming Shao xiang-wei Liao Liang Zhao Department of Engineering Mechanics Zhejiang UniversityHangzhou310027China Iron and Steel Research Institutes of Ansteel Group Corporation Anshan114009China State Key Laboratory of Metal Material for Marine Equipment and Application Anshan114009China

The measurement of two-phase velocities in bubble flows using laser Doppler velocimetry(LDV)is *** key to the problem is to differentiate the LDV signals from bubbles and tracers,based on which the two-phase velocities can be *** this study,two experiments are carried ***,the bubble-chain experiment is performed to investigate the optical response of bubble surface and the corresponding LDV *** optical response shows that the light received by the LDV detector is dominated by the reflection component,which is similar to specular reflection to some *** are three typical patterns of signals of large bubbles passing through the measurement volume,all of which are with high amplitude and ***,the upward-flow experiment is conducted to study the statistical characteristics of large bubbles as well as micro tracers and micro *** results show that the amplitude of signal of millimeter bubbles is about an order of magnitude larger than that of tracers or micro *** on this significant difference of the amplitude,we propose a phase discrimination method to distinguish two-phase *** capability of the proposed method is tested in a complex bubble flow,and its reliability is verified by bubble tracking velocimetry(BTV)technology.

关键词： laser Doppler velocimetry(LDV) bubbly flow phase discrimination bubble tracking velocimetry(BTV)

Computed tomography-based radiomics to predict early recurrence of hepatocellular carcinoma post-hepatectomy in patients background on cirrhosis

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World Journal of Gastroenterology 2024年第15期30卷 2128-2142页

作者： Gui-xiang Qian Zi-ling Xu Yong-Hai Li Jian-Lin Lu xiang-Yi Bu Ming-Tong wei wei-Dong Jia Department of Hepatic Surgery Anhui Provincial HospitalThe First Affiliated Hospital of USTCDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Hepatic Surgery Anhui Provincial Hospital Affiliated to Anhui Medical UniversityAnhui Medical UniversityHefei 230001Anhui ProvinceChina Department of Anorectal Surgery the First People’s Hospital of HefeiHefei 230001Anhui ProvinceChina

BACKGROUND The prognosis for hepatocellular carcinoma(HCC)in the presence of cirrhosis is unfavourable,primarily attributable to the high incidence of *** To develop a machine learning model for predicting early recurrence(ER)of posthepatectomy HCC in patients with cirrhosis and to stratify patients’overall survival(OS)based on the predicted risk of *** In this retrospective study,214 HCC patients with cirrhosis who underwent curative hepatectomy were *** feature selection was conducted using the least absolute shrinkage and selection operator and recursive feature elimination ***-radiologic features were selected through univariate and multivariate logistic regression *** machine learning methods were used for model comparison,aiming to identify the optimal *** model’s performance was evaluated using the receiver operating characteristic curve[area under the curve(AUC)],calibration,and decision curve ***,the Kaplan-Meier(K-M)curve was used to evaluate the stratification effect of the model on patient *** Within this study,the most effective predictive performance for ER of post-hepatectomy HCC in the background of cirrhosis was demonstrated by a model that integrated radiomics features and clinical-radiologic *** the training cohort,this model attained an AUC of 0.844,while in the validation cohort,it achieved a value of *** K-M curves illustrated that the combined model not only facilitated risk stratification but also exhibited significant discriminatory ability concerning patients’*** The combined model,integrating both radiomics and clinical-radiologic characteristics,exhibited excellent performance in HCC with *** K-M curves assessing OS revealed statistically significant differences.

关键词： Machine learning Radiomics Hepatocellular carcinoma Cirrhosis Early recurrence Overall survival Computed tomography Prognosis Risk factor Delta-radiomics

STAT5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia

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Signal Transduction and Targeted Therapy 2023年第10期8卷 5106-5118页

作者： Ze-wei Huang Xue-Ning Zhang ling Zhang ling-ling Liu Jing-Wen Zhang Yu-xiang Sun Jue-Qiong Xu Quentin Liu Zi-Jie Long Department of Hematology The Third Affiliated HospitalSun Yat-sen UniversityInstitute of HematologySun Yat-sen UniversityGuangzhouChina Department of Nephrology The Third Affiliated Hospitalun Yat-sen UniversityGuangzhouChina Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaSun Yat-sen UniversityGuangzhouChina

Immunotherapy is a revolutionized therapeutic strategy for tumor treatment attributing to the rapid development of genomics and immunology,and immune checkpoint inhibitors have successfully achieved responses in numbers of tumor types,including hematopoietic ***,acute myeloid leukemia(AML)is a heterogeneous disease and there is stll a lack of systematic demonstration to apply immunotherapy in AML based on PD-1/PD-L1 blockage.

关键词： myeloid acute leukemia

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao De-En Xu Ming-Lei Wu Ji-Chuan Liu Zi-ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response