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Effect of inhibition of GABA uptake in the tuberomamillary nucleus on sleep-waking states following the ventrolateral preoptic area lesion in rats

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Effect of inhibition of GABA uptake in the tuberomamillary n...

Estimation in Discrete Reliability Growth,a Growth Model with Coefficient Condition

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Min ZHANG,Kun FAN,Peng ZHAO,Yu-Feng shao,xiang-Pan kong,Qiong YAN,Yi-Ping HOU~* Department of Neuroscience,Anatomy,Histology and Embryology,Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,China

＜正＞Objective Neurons containing gamma-aminobutyric acid（GABA） play an important role in the regulation from wakefulness to *** evidences have demonstrated that the interaction between GABAergic neurons in ventrolateral preoptic area（VLPO） and histaminergic（HA） neurons in the tuberomammillary nucleus（TMN） play a key role for regulating sleep-wakefulness *** neurons also in the TMN have been recently documented. However,GABAergic neurons in TMN have not received much attention for their role in sleep-wakefulness cycle. The present study was to investigate the effect of inhibition of GABA uptake in the TMN nucleus on sleep-waking states following the VLPO lesion and further understand the role of the GABAergic neurons in the TMN in sleep-wakefulness *** Thirty adult and male SD rats were used in this *** anesthesia,4 EEG screw electrodes were implanted into the skull and 3 flexible EMG wire electrodes were placed into the nuchal muscles. After 24 h basal record of sleep-wake cycle,microliter syringes containing ibotenic acid（IA,Sigma,***,USA） solution（10 nmol/0.5μL/side） were bilaterally injected into the VLPO for specific cells *** VLPO lesion, nipecotic acid（NPA,Sigma,***,USA）,a GABA uptake inhibitor（1 mmol/0.5μL/side）,was bilaterally injected into the TMN at 10:00 or 22:00 h for observing the changes of sleep-waking states in light period（8:00-20:00 h） and dark period（20:00-8:00 h） on day 8,10,12 and 14,*** recording,histological Nissl staining and immunohistochemical Fos and glutamate decarboxylase（GAD） staining were respectively performed for determining the loss number of cell and GABA neurons in the *** immunoreactivity（IR） and histidine decarboxylase （HDC）-IR were performed determining the distributions and morphologic characteristics of GABAergic and HAergic neurons in the ***（1） Effect of VLPO lesion on sleep-waking cycle and cortical EEG *** VLPO lesion,the sleep-wa

关键词： GABAergic neuron GABA uptake inhibitor histaminergic neuron lesion glutamate decarboxylaseimmunoreactivity histidine decarboxylase-immunoreactivity tuberomammillary nucles ventrolateral preoptic area

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Journal of Systems Science & Complexity 2016年第4期29卷 1112-1122页

作者： shao xiang FANG xiangzhong School of Mathematics Science Peking UniversityBeijing 100871China

This paper considers the well known problem of estimating reliability in discrete reliability growth context with sequence of dichotomous success-failure outcomes. More precisely, the authors generalize the simple order relationship constraint with some coefficients. The authors prove that under some mild conditions, the generalized constraint MLE problem can be transformed to a traditional isotonic problem. The authors also study the lower confidence limit estimation of reliability with sample space ranking method. A simulation is conducted to illustrate the superiority of the proposed method.

关键词： Confidence limit discrete reliability growth isotonic regression point estimation

Effect of silk sericin on morphology and structure of calcium carbonate crystal

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Frontiers of Materials Science 2013年第2期7卷 177-183页

作者： Rui-Bo ZHAO Hua-Feng HAN shao DING Ze-Hao LI xiang-Dong kong Xinyuan Institute of Medicine and Biotechnology College of Life Sciences Zhejiang Sci-Tech University Hangzhou 310018 China College of Materials and Textile Zhejiang Sci-Tech University Hangzhou 310018 China

In this paper, silk sericin was employed to regulate the mineralization of calcium carbonate （CaC03）. CaCO3 composite particles were prepared by the precipita- tion reaction of sodium carbonate with calcium chloride solution in the presence of silk sericin. The as-prepared samples were collected at different reaction time to study the crystallization process of CaCO3 by scanning electron microscopy （SEM）, Fourier transform infrared spectroscopy （FTIR）, thermogravimetric analysis （TGA） and X-ray diffraction （XRD）. The results showed that silk sericin significantly affected the morphology and crystallographic polymorph of CaCO3. With increasing the reaction time, the crystal phase of CaCO3 transferred from calcite dominated to vaterite dominated mixtures, while the morphology of CaCO3 changed from disk-like calcite crystal to spherical vaterite crystal. These studies showed the potential of silk sericin used as a template molecule to control the growth of inorganic crystal.

关键词： silk sericin calcium carbonate (CaC03) calcite vaterite biomineralization

High-resolution imaging through dynamic scattering media: Iterative optimization based on polarimetric characteristics

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Science China Technological Sciences 2025年第1期 82-84页

作者： Meng xiang Kai DENG Tianyu WANG Jinpeng LIU Xue DONG Teli XI Fei LIU Xiaopeng shao School of Optoelectronic Engineering Xidian University Xi'an Key Laboratory of Computational Imaging National Key Laboratory of Infrared Detection Technologies

High-resolution imaging through randomly dynamic scattered fields and highly scattered walls is an extensively sought-after capability with potential applications in various fields such as underwater imaging, biomedical imaging, and seeing through fog. Numerous methods have been proposed to unscramble object information from degraded scattered images, resulting in considerable improvements in image contrast in degraded scenarios [1].

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Ensemble deep transfer learning driven by multisensor signals for the fault diagnosis of bevel-gear cross-operation conditions

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Science China(Technological Sciences) 2021年第3期64卷 481-492页

作者： DI ZiYang shao HaiDong xiang JiaWei State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body College of Mechanical and Vehicle EngineeringHunan UniversityChangsha 410082China College of Mechanical and Electrical Engineering Wenzhou UniversityWenzhou 325035China

The existing intelligent fault diagnosis techniques of bevel gear focus on single-sensor signal analysis under the steady operation *** this study,a new method is proposed based on ensemble deep transfer learning and multisensor signals to enhance the fault diagnosis adaptability and reliability of bevel gear under various operation ***,a novel stacked autoencoder(NSAE)is constructed using a denoising autoencoder,batch normalization,and the Swish activation ***,a series of source-domain NSAEs with multisensor vibration signals is ***,the good model parameters provided by the source-domain NSAEs are transferred to initialize the corresponding target-domain ***,a modified voting fusion strategy is designed to obtain a comprehensive *** multisensor signals collected under the different operation conditions of bevel gear are used to verify the proposed *** comparison results show that the proposed method can diagnose different faults in an accurate and stable manner using only one target-domain sample,thereby outperforming the existing methods.

关键词： ensemble deep transfer learning bevel-gear fault diagnosis novel stacked autoencoder multisensor signals modified voting fusion strategy

Local Bifurcation of Critical Periods for a Class of Liénard Equations

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Acta Mathematicae Applicatae Sinica 2014年第3期30卷 627-634页

作者： Yi shao Chun-xiang A School of Mathematics and Statistics Zhaoqing University

In this paper, we study the local bifurcation of critical periods near the nondegenerate center （the origin） of a class of Li@nard equations with degree 2n, and prove that at most 2n - 2 critical periods （taken into account multiplicity） can be produced from a weak center of finite order. We also prove that it can have exactly 2n - 2 critical periods near the origin.

关键词： period function critical periods local bifurcation

Determination of Trace Elements in Edible Nuts in the Beijing Market by ICP-MS

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Biomedical and Environmental Sciences 2015年第6期28卷 449-454页

作者： YIN Liang Liang TIAN Qing shao Xian Zhang kong xiang Yin JI Yan Qin National Institute for Radiological Protection Chinese Center for Disease Control and Prevention

Nuts have received increased attention from the public in recent years as important sources of some essential elements, and information on the levels of elements in edible nuts is useful to consumers. Determination of the elemental distributions in nuts is not only necessary in evaluating the total dietary intake of the essential elements, but also useful in detecting heavy metal contamination in food. The aim of this study was to determine the mineral contents in edible nuts, and to assess the food safety of nuts in the Beijing market. Levels of Li, Cr, Mn, Co, Cu, Zn, As, Se, Rb, Sr, Mo, Cd, Cs, Ba, Pb, Th, and U in 11 types of edible nuts and seeds （macadamia nuts, lotus nuts, pistachios, sunflower seeds, pine nuts, almonds, walnuts, chestnuts, hazelnuts, cashews, and ginkgo nuts） as well as raisins were determined by inductively coupled plasma mass spectrometry （ICP-MS）. The accuracy of the method was validated using standard reference materials GBWlO014 （cabbage） and GBWlO016 （tea）. Our results provide useful information for evaluating the levels of trace elements in edible nuts in the Beijing market, will be helpful for improving food safety, and will aid in better protecting consumer interests.

关键词： edible contamination detecting intake evaluating dietary Brazil digestion representing recognize

Synthesis,Structure and Magnetic Behavior of a Novel Series of Trinuclear Windwheel Complexes

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Chinese Journal of Chemistry 2023年第24期41卷 3662-3668页

作者： Rong Luo Chen-Ze Xie Ming-Guang Chen Hai-Yan Shi xiang-Jian kong Yu-Hua Fan Feng shao Key Laboratory of Marine Chemistry Theory and Technology Ministry of EducationCollege of Chemistry and Chemical EngineeringOcean University of ChinaQingdaoShandong266100 China Baotou Research Institute of Rare Earths BaotouInner Mongolia014040 China State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamenFujian361005 China

A new family of trinuclear windwheel complexes with molecular formula [M^(II)_(3)(tpa)_(3)(μ-ttc)](ClO_(4))_(3)·n(sol) (ttc = 1,3,5-triazine-2,4,6-trithiol;tpa = tris(2-pyridylmethyl)amine;M = Mn,n = 2,sol = CH_(3)CN,1;M = Co,n = 1,sol = CH_(3)CN,2;M = Ni,n = 0,3) were synthesized and ***-crystal X-ray diffraction revealed that three metal centers in 1—3 are connected by ttc bridge,forming a regular triangular MII3 *** metal center is bonded by chelating S,N atoms from ttc and by N atoms from *** studies showed that 1—3 displayed antiferromagnetic behavior and further gave the easy-axis anisotropy (D = −0.77 cm^(−1) for 1 and −8.13 cm^(−1) for 2) and easy-plane anisotropy (D = 5.08 cm^(−1) for 3).Moreover,2 exhibited field-induced slow magnetic relaxation behavior and their effective energy barriers were roughly evaluated Ueff = 6.9 K.

关键词： Cluster compounds Crystal growth Magnetic properties Slow magnetic relaxation Magnetic anisotropy

Conditional Generation of Multiparticle Entanglement via Cavity QED

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Communications in Theoretical Physics 2009年第11期52卷 835-839页

作者： xiang shao-Hua shao Bin SONG Ke-Hui Department of Physics and Information Engineering Huaihua University Huaihua 418008 China Research Institute of Information Science Huaihua University Huaihua 418008 China Department of Physics Beijing Institute of Technology Beijing 100081 China

We propose a simple scheme to not only generate GHZ states and W states of the multiparticle but also form a new category of multiparticle entangled states by letting the A-type three-level atoms simultaneously interacting with a coherent cavity field followed by the selective measurements on the cavity mode. We investigate the influence of the cavity dissipation on the generated entangled state and discuss the experimental feasibility of our scheme. It is shown that the intensity of the coherent cavity field plays an instructive role in contribution to state preparation process while the cavity decay and the detuning between the atoms and cavity mode result in the deterioration of the generated entangled state.

关键词： multiparticle entanglement gavity QED decoherence