检索结果-南通市图书馆

Meta-analysis of the success rate of heartbeat recovery in patients with prehospital cardiac arrest in the past 40 years in China

引用

Military Medical Research 2020年第4期7卷 430-443页

作者： xiang-min gu Shi-Bin Yao Zhong-Jie He Yong-Gang Wang Zhi-Hui Li Tianjin Binhai New Area Center for Disease Control and Prevention Tianjin 300450China Emergency Department Affiliated Hospital of Chifeng CollegeChifeng 024005Inner MongoliaChina The Fourth Medical Center of Chinese PLA General Hospital Beijing 100048China Beijing Platinum Ten minutes Time-effect Emergency Technology Research Academy Beijing 100039China Beijing Chaoyang District Jiangtai Community Health Service Center Beijing 100016China

Background:Systematic evaluation of the successful heartbeat recovery rate(HRR)in patients during the platinum ten minutes after cardiac ***:The databases of CNKI(January 1979–March 2019),Chongqing VIP(January 1989–March 2019),Wanfang(January 1990–March 2019)and Web of Science(January 1900-May 2020)were *** collect the clinical data of patients with cardiac arrest before hospitalization and analyze the cardiopulmonary resuscitation(CPR)at different *** selection and data extraction were carried out by two researchers independently,and the meta package of R software(version 3.61)was used for ***:A total of 116 papers met the inclusion criteria,including 37,181 *** these patients,3367 had their heartbeats successfully *** results showed a high degree of heterogeneity(χ2=6999.21,Pguide 2000,2005,2010,2015 and other versions),the HRR of other versions[0.264(0.176–0.375)]was higher than the International Cardiopulmonary Resuscitation 2005 edition[0.121(0.092–0.158)].(2)The rescue time was divided into the 0 to≤5 min group,the 5 to≤10 min group,the 10 to≤15 min group,and the>15 min *** HRR were 0.417(0.341–0.496),0.143(0.104–0.193),0.049(0.034–0.069),and 0.022(0.009–0.051),*** HRR was higher in the 0 to≤5 min group than in the 5 to≤10 min group,the 10 to≤15 min group and the>15 min *** was no difference between the 10 to≤15 min group and the>15 min group.(3)When the groups were stratified with the cutoff of 10 min,the≤10 min group HRR[0.250(0.202–0.306)]was higher than the>10 min group rate[0.041(0.029–0.057)].(4)The HRR of the telephone guidance group was[0.273(0.227–0.325)]lower than that of the 0 to≤5 min group[0.429(0.347–0.516)]but higher than that of the 5 to≤10 min group,the 1

关键词： Sudden cardiac arrest Cardiopulmonary resuscitation Peri-cardiac arrest period Platinum 10 min Meta-analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A meta-analysis of the success rates of heartbeat restoration within the platinum 10min among outpatients suffering from sudden cardiac arrest in China

引用

Journal of Medical Colleges of PLA(China) 2016年第1期31卷 1-14页

作者： xiang-min gu Zhi-Hui Li Zhong-jie He Zhe-Wei Zhao Shuang-Qing Liu School of Graduate Liaoning Medical College Department of ICU First Affiliated HospitalGeneral Hospital of PLA

Background:The optimal time to save a person who has had a sudden cardiac arrest is within the first few minutes of the *** compression and early defibrillation should be performed at this *** is the key to successful CPR; as such,*** proposed the 'platinum 10 min' system to study early CPR *** paper systematically evaluates the success rates of heartbeat restoration within the 'platinum 10min' among patients suffering from sudden cardiac ***:The clinical data of outpatients suffering from a cardiac arrest were retrieved from the China Knowledge Network(January 1975-January 2015),the Chongqing VIP database(January 1989-January 2015),and the Wanfang database(January 1990-January 2015).The success of the cardiopulmonary resuscitation(CPR) performed at different times after the patients had cardiac arrests was *** researchers screened the literature and extracted the data independently.A meta-analysis was conducted using Stata 12.0.A total of 57 papers met the inclusion criteria,including 29,269 *** these patients,1,776 had their heartbeats successfully *** results showed high heterogeneity(χ~2=3428.85,Pguidelines for CPR and Emergency Cardiovascular Care,that described in the 2005 version,2010 version,and another CPR method.2) The patients were divided into five groups based on the time when CPR was performed:the ?1min group,the 1-5min group,the 5-10 min group,the 10-15 min group and the >15min *** CPR success rates of these five groups were 0.247(0.15-0.344),0.353(0.250-0.456),0.136(0.109-0.163),0.058(0.041-0.075),and 0.011(0.004-0.019),*** CPR success rates did not differ between the patie

关键词： Cardiac arrest Cardiopulmonary resuscitation Meta-analysis Platinum 10 minutes Time-efficiency First aid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

nfluence of Marital Status on the Quality of Life of Chinese Adult Patients with Epilepsy

引用

Chinese Medical Journal 2017年第1期130卷 83-87页

作者： Fu-Li Wang xiang-min gu Bao-Yun Hao Shan Wang Ze-Jie Chen Cheng-Yun Ding Department of Hospital Management First Affiliated Hospital General Hospital of People's Liberation Army Beijing 100048 China Department of Programmed Immunization Center for Disease Control and Prevention of Tianjin Binhai New Area Tianjin 300450 China Department of Epilepsy First Affiliated Hospital General Hospital of People's Liberation Army Beijing 100048 China

Background： Epilepsy is a chronic disorder characterized by recurrent seizures and has significant psychological and social consequence for everyday living. Epilepsy affects various aspects of ones＇ social life. The present study aimed to investigate the influence of marital status on the quality of life of adult Chinese patients with epilepsy. Methods： This study surveyed 805 Chinese adults who have been clinically diagnosed with epilepsy for longer than 1 year in 11 hospitals in Beijing. In this survey, 532 （66.1%） participants were married. All of them completed the case report form with enquiries on demographic data, social factors, and illness. The marriage status of adult epileptic quality of life was the dependent variable, and demographic data and clinical data were independent variables, analyzed through the multiple linear regression analysis methods. The patients＇ quality of life was assessed using the Quality of Life in patients with Epilepsy-31 items （QOLIE-31） questionnaire, the Patient Health Questionnaire-9 items （PHQ-9）, and the Generalized Anxiety Disorder-7 items （GAD-7）. Results： The PHQ-9 and GAD-7 scores in the unmarried group （PHQ-9 = 6.0 and GAD-7 = 5.0） were significantly higher than that of the married group （PHQ-9 = 4.0 and GAD-7 =3.0）. The scores of married adult patients with epilepsy on QOLIE （61.8 ±15.3） and social function （70.9 ± 22.7） were higher than the scores of the unmarried patients aged between 20 and 44 years. The scores of married adult epileptics on the QOLIE （58,4 ± 14.6） and the energy/fatigue （62.1 ± 20.4） were higher than the scores of the unmarried patients （QOLIE = 58.4 ± 14.6 and the energy/fatigue = 62.1 ±20.4） aged between 45 and 59 years. For the adult epilepsy patients, depression, anxiety, seizures within the last year, disease course, medical expense category, and marriage＊ age are negatively correlated with the quality of life. Occupation, educational level, and average monthly income are closely related to th

关键词： Adults Epilepsy Marital Status Quality of Life

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of Positron Emission Tomography Using 2-[^18F]-fluoro-2-deoxy-D-glucose and 3-deoxy-3-[^18F]-fluorothymidine in Lung Cancer Imaging

引用

Chinese Medical Journal 2016年第24期129卷 2926-2935页

作者： Fu-Li Wang Ye-Ying Tan xiang-min gu Tian-Ran Li guang-ming Lu Gang Liu Tian-Long Huo Department of Hospital Management The First Affiliated Hospital of Chinese PLA General Hospital Beijing 100048 China Department of Radiology Xuzhou Center Hospital Xuzhou Jiangsu 221000 China Department of Radiology The First Affiliated Hospital of Chinese PLA General Hospital Beijing 100048 China Department of Radiology Nanjing General Hospital of Chinese PLA Nanjing Jiangsu 210000 China Department of Radiology Peking University People's Hospital Beijing 100048 China

Background： The detection of solitary pulmonary nodules （SPNs） that may potentially develop into a malignant lesion is essential for early clinical interventions. However, grading classification based on computed tomography （CT） imaging results remains a significant challenge. The 2-[^18F]-fluoro-2-deoxy-D-glucose （^18F-FDG） positron emission tomography （PET）/CT imaging produces both false-positive and false-negative findings for the diagnosis of SPNs. In this study, we compared 18F-FDG and 3-deoxy-3-[^18F]-fluorothymidine （^18F-FLT） in lung cancer PET/CT imaging. Methods： The binding ratios of the two tracers to A549 lung cancer cells were calculated. The mouse lung cancer model was established （n = 12）, and micro-PET/CT analysis using the two tracers was performed. Images using the two tracers were collected from 55 lung cancer patients with SPNs. The correlation among the cell-tracer binding ratios, standardized uptake values （SUVs）, and Ki-67 proliferation marker expression were investigated. Results： The cell-tracer binding ratio for the A549 cells using the ^18F-FDG was greater than the ratio using 18F-FLT （P 〈 0.05）. The Ki-67 expression showed a significant positive correlation with the ^18F-FLT binding ratio （r = 0.824, P〈 0.01）. The tumor-to-nontumor uptake ratio of ^18F-FDG imaging in xenografts was higher than that of ^18F-FLT imaging. The diagnostic sensitivity, specificity, and the accuracy of ^18F-FDG for lung cancer were 89%, 67%, and 73%, respectively. Moreover, the diagnostic sensitivity, specificity, and the accuracy of ^18F-FLT for lung cancer were 71%, 79%, and 76%, respectively. There was an obvious positive correlation between the lung cancer Ki-67 expression and the mean maximum SUV of ^18F-FDG and ^18F-FLT （r = 0.658, P〈 0.05 and r = 0.724, P〈 0.01, respectively）. Conclusions： The ^18F-FDG uptake ratio is higher than that of ^18F-FLT in A549 cells at the cellular level.^18F-FLT imaging might be superior for the quantitative diagnosis of lung

关键词： 2-[^18F]-fluoro-2-deoxy-D-glucosc 2-[^18F ]-fluoro-2-deoxy-D-glucose and 3-deoxy-3-[^18F]-fluorothymidine Computed Tomography Lung Cancer Positron Emission Tomography Solitary Pulmonary Nodules Standardized Uplake Value

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

nfluence of Occupational Status on the Quality of Life o Chinese Adult Patients with Epilepsy

引用

Chinese Medical Journal 2016年第11期129卷 1285-1290页

作者： xiang-min gu Cheng-Yun Ding NingWang Cheng-Feng Xu Ze-Jie Chen Qin Wang Qin Yao Fu-Li Wang Department of Epilepsy Graduate Training Base of Jinzhou Medical University First Affiliated Hospital of Chinese People's Liberation Army General Hospital Beijing 100048 China Department of Epilepsy First Affiliated Hospital General Hospital of People's Liberation Army Beijing 100048 China Department of Hospital Management First Affiliated Hospital General Hospital of People's Liberation Army Beijing 100048 China

Background： Epilepsy is one of the most common serious neurological disorders. The present study aimed to investigate the influence of occupational status on the quality of life of Chinese adult patients with epilepsy. Methods： This study surveyed 819 subjects clinically diagnosed with epilepsy for more than 1 year in 11 hospitals in Beijing; 586 were employed （71.55%）. All subjects completed the case report form with inquiries on demographic data, social factors, and illness. The patients＇ quality of life was assessed using the quality of life in patients with epilepsy-31 items （QOLIE-31） questionnaire. Results： The QOLIE-31 score in the employed group was significantly higher than that in the unemployed group. Furthermore, the scores in all the sections （overall quality of life, energy/fatigue, emotional well-being, seizure worry, cognition, social function, and medication effects） of the employed group were higher than those of the unemployed group. Both the employed and unemployed groups achieved the highest difference in social function. The QOLIE-31 score of students was higher than those of farmers and workers. Both the students and workers scored higher in the quality of life compared with the adult peasants living with epilepsy. The students and farmers showed significant differences in QOL1E-31 score, cognition, emotional well-being, overall quality of life, energy/fatigue, and social function. In contrast, no significant difference was noted in seizure worry and medication effects across the three different kinds of occupation. Conclusion： Occupational status might affect the quality of life of Chinese adult patients with epilepsy, and social function is the most important contributing factor.

关键词： Adults Epilepsy Occupational Status Quality of Life

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

引用

Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： mingyu Zhang Chunyu xiang Renrui Niu Xiaodong He Wenqi Luo Wanguo Liu Rui gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Direct Photolithography of WO_(x)Nanoparticles for High‑Resolution Non‑Emissive Displays

引用

Nano-Micro Letters 2025年第3期17卷 297-309页

作者： Chang gu guojian Yang Wenxuan Wang Aiyan Shi Wenjuan Fang Lei Qian Xiaofei Hu Ting Zhang Chaoyu xiang Yu‑Mo Zhang Laboratory of Optoelectronic Information Technology and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201People’s Republic of China Hangzhou Bay Laboratory of Advanced Nano‑Optoelectronic Materials and Devices Qianwan Institute of CNITECHNingbo 315336People’s Republic of China Smart Materials for Architecture Research Lab Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100People’s Republic of China University of Science and Technology of China Hefei 230026People’s Republic of China State Key Lab of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012People’s Republic of China

High-resolution non-emissive displays based on electrochromic tungsten oxides(WOx)are crucial for future near-eye virtual/augmented reality interactions,given their impressive attributes such as high environmental stability,ideal outdoor readability,and low energy ***,the limited intrinsic structure of inorganic materials has presented a significant challenge in achieving precise patterning/pixelation at the micron ***,we successfully developed the direct photolithography for WOx nanoparticles based on in situ photo-induced ligand *** strategy enabled us to achieve ultra-high resolution efficiently(line width3600 cycles),as well as promising applications in electronic logos,pixelated displays,flexible electronics,*** success and advancements presented here are expected to inspire and accelerate research and development(R&D)in high-resolution non-emissive displays and other ultra-fine micro-electronics.

关键词： Electrochromic Direct photolithography WOx nanoparticles In situ photo-induced ligand exchange High-resolution displays

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rapid and scalable preparation of highly quaternized polymer networks to achieve efficient simultaneous adsorption of iodide and pertechnetate

引用

Science China Chemistry 2025年第1期68卷 337-349页

作者： Meiyun Xu Song gu Fulong Chen Zhe Zhao Peng Liu Daoben Hua State Key Laboratory of Radiation Medicine and Protection School of Radiological and Interdisciplinary Sciences (RAD-X) Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions Soochow University

The efficient separation of fission products,such as TcO4-and I-,holds strategic significance for the management of radioactive wastes and environmental *** this study,we propose an ultrafast strategy for scalable preparation of a highly quaternized organic network to facilitate efficient and synchronous separation of iodide and *** network can be prepared within a few minutes at room temperature,using polyethylenimine and 1,2,4,5-tetrakis（bromomethyl）benzene as building *** chlorine replacement,the network,abundantly decorated with quaternary ammonium groups （Cl@QPN）,exhibits an ultrahigh positive charge density of 7.6 mmol/*** enables the rapid and efficient enrichment of target anions through strong electrostatic Coulomb *** a result,Cl@QPN exhibits significantly higher adsorption rate constants of 0.830 g/（mg min） for ReO4-（a nonradioactive surrogate of TcO4-） and 0.677 g/（mg min） for I-compared to other ***,it possesses high adsorption capacities,reaching 1,681 mg/g for ReO4-and 917.4 mg/g for I-.Cl@QPN also demonstrates good selectivity towards target ions and shows efficient adsorption for99TcO4-.Additionally,Cl@QPN exhibits high dynamic processing capacities,handling up to 3,100 and 7,400 kg of simulated streams per kilogram of material for I-and ReO4-,respectively.

关键词： quaternized polymer networks adsorption pertechnetate iodide liquid radioactive streams

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

引用

Science China Life Sciences 2025年第1期68卷 300-302页

作者： Ze-min Lin Mai xiang Wen-Hui Wei Shu-Hui Fan Li Chen Jie Wang Xiao-Qian Yang Chun-Hao Yang Shi-Jun He Jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Take precautions against potential threats that carbon nanotubes may bring to you

引用

Science China Chemistry 2020年第2期63卷 141-142页

作者： min Luo Ziying xiang Zhanjun gu CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China College of Materials Science and Optoelectronic Technology University of Chinese Academy of SciencesBeijing 100049China

Long-term pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) may promote breast cancer metastasis and rapid colonization in the lungs and other organs according to recent research conducted by *** Chen,*** Z... 详细信息

关键词： carbon potential organs

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：