检索结果-南通市图书馆

Insect Science 2020年第4期27卷 756-770页

作者： xiang-zhao yue Dan Li Jun Lv Kai Liu Jie Chen Wen-Qing Zhang State Key Laboratory of Biocontrol and School of Life Sciences Sun Yat-sen UniversityGuangzhouChina

The tracheal apical extracellular matrix(aECM)is vital for expansion of the tracheal lumen and supports the normal structure of the lumen to guarantee air entry and circulation in *** it has been found that some cuticular proteins are involved in the organization of the aECM,unidentified factors still ***,we found that mind the gap(Mtg),a predicted chitin-binding protein,is required for the normal formation of the apical chitin matrix of airway tubes in the model holometabolous insect Drosophila *** to chitin,the Mtg protein was linearly arranged in the tracheal dorsal trunk of the tracheae in *** mtg expression in the tracheae seriously affected the viability of larvae and caused tracheal chitin spiral defects in some *** of mtg mutant showed that mtg was required for normal development of tracheae in *** taenidial folds of some mtg mutant embryos were found on either lateral view of tracheal dorsal trunk or internal view of transmission electron microscopy *** abnormal tracheae were not fully filled with gas and accompanied by a reduction in tracheal width,which are characteristic phenotypes of tracheal aECM ***,in the hemimetabolous brown planthopper(BPH)Nilapat'vata lugens,downregulation of NICPAP1-N(a homolog of mtg)also led to the formation of abnormal tracheal chitin spirals and *** results suggest that mtg and its homolog are involved in the proper organization of the tracheal aECMs in flies and BPH,and that this function may be conserved in insects.

关键词： chitin Drosophila melanogaster,extracellular matrix mind the gap Nilapm vata lugens trachea

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin Li Jian xiang Lu Qiu Xiaohan Chen Yinkun zhao Yujue Wang Qu yue Taotao Gao Wenlong Liu Dan Xiao zhaoyu Jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

利用可控量子门在非对称多体纠缠通道中实现量子态隐形传输网络

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

量子光学学报 2016年第4期22卷 341-347页

作者：郝翔戴玥赵碧轩朱士群苏州科技大学数理学院物理系江苏苏州215009 苏州大学物理系江苏苏州215006

本文通过一系列的双量子位逻辑门构造非对称多体量子纠缠态。以此态作为量子隐形传输通道,利用全局幺正操作和定域性测量,我们可以让未知态在任意一个接收端重现,从而实现量子信息一对多的网络式传输。同时,充分考虑实际量子系统的局域... 详细信息

本文通过一系列的双量子位逻辑门构造非对称多体量子纠缠态。以此态作为量子隐形传输通道,利用全局幺正操作和定域性测量,我们可以让未知态在任意一个接收端重现,从而实现量子信息一对多的网络式传输。同时,充分考虑实际量子系统的局域环境噪声对量子传输效率的影响。

关键词：量子隐形传输量子门多体量子纠缠态局域噪声环境平均保真度

在线全文

学校读者我要写书评

暂无评论

狂犬病疫苗佐剂研究新进展

中国生物制品学杂志 2018年第12期31卷 1397-1401页

作者：赵祥月普梦笛鲁卫东昆明医科大学药学院暨天然药物药理重点实验室

狂犬病病毒(rabies virus,RABV)是传染性强、死亡率高、受到人们广泛关注的一种烈性病毒。狂犬病疫苗作为目前唯一能预防和控制狂犬病的制剂,其研发和生产日益成为热点。佐剂是能增强或改变抗原特异性免疫应答从而辅助疫苗发挥作用的物... 详细信息

狂犬病病毒(rabies virus,RABV)是传染性强、死亡率高、受到人们广泛关注的一种烈性病毒。狂犬病疫苗作为目前唯一能预防和控制狂犬病的制剂,其研发和生产日益成为热点。佐剂是能增强或改变抗原特异性免疫应答从而辅助疫苗发挥作用的物质。目前上市的狂犬病疫苗主要为铝佐剂疫苗及无佐剂疫苗,但上述两种疫苗均存在较大的局限性,在一定程度上影响了狂犬病疫苗的使用效果,因此本文在对RABV及其致病机理进行综述的基础上,对狂犬病疫苗佐剂进行探讨。

关键词：狂犬病疫苗佐剂

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao Shuyue Li Cui Chang xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

基于自组装纳米颗粒探针的全错位排列问题的DNA计算模型

在线全文

学校读者我要写书评

暂无评论

阜阳师范学院学报（自然科学版） 2017年第3期34卷 60-63页

作者：巩成艳殷志祥赵鑫月安徽理工大学数学与大数据学院安徽淮南232001

全错位排列问题是组合数学中的一类重要问题,可转化为范式的形式,利用自组装纳米颗粒探针对满足性问题进行求解。将纳米金颗粒和DNA序列进行结合,形成纳米金颗粒探针的识别区,并且成拱形结构。当识别区与其补链发生杂交反应时,拱形结构... 详细信息

全错位排列问题是组合数学中的一类重要问题,可转化为范式的形式,利用自组装纳米颗粒探针对满足性问题进行求解。将纳米金颗粒和DNA序列进行结合,形成纳米金颗粒探针的识别区,并且成拱形结构。当识别区与其补链发生杂交反应时,拱形结构打开并发出荧光,从而给出了全错位排列问题的一种新的DNA计算模型。与传统的DNA计算模型不同,本文将纳米技术和DNA计算理论相结合。

关键词： DNA计算自组装纳米颗粒全错位排列问题

在线全文

学校读者我要写书评

暂无评论

太子河流域生境质量及其与社会经济的关系

生态学杂志 2017年第10期36卷 2917-2925页

作者：王琼卢聪韩青范志平刘杰李法云涂志华王善祥赵悦辽宁石油化工大学生态环境研究院辽宁抚顺113001 辽宁石油化工大学化学化工与环境学部辽宁抚顺113001 中国科学院沈阳应用生态研究所沈阳110016 辽宁老秃顶子国家级自然保护区辽宁抚顺113208

采用主成分分析(PCA)与熵权相结合的方法,对太子河流域生境质量进行评价,并运用相关分析和冗余分析的方法识别社会经济发展和土地利用方式对生境质量的影响。结果表明:太子河流域生境质量等级为好的河段占4.35%,较好和一般的河段占91.3... 详细信息

采用主成分分析(PCA)与熵权相结合的方法,对太子河流域生境质量进行评价,并运用相关分析和冗余分析的方法识别社会经济发展和土地利用方式对生境质量的影响。结果表明:太子河流域生境质量等级为好的河段占4.35%,较好和一般的河段占91.30%,差的河段占2.17%;生境质量等级较好的河段主要位于上游地区,中游地区生境质量一般,下游鞍山段的生境质量较差;流域社会经济发展和土地利用方式是影响生境质量的主要因素,相关分析和冗余分析均显示生境质量与人口密度、人均地区生产总值、第一产业、第二产业,以及与耕地、建设用地面积比例呈显著负相关关系,而与林地面积比例呈显著正相关;社会经济状况和土地利用方式能分别解释流域生境质量特征的45.7%和39.5%;合理配置产业结构、优化土地利用方式可有效地逐步改善太子河流域生境质量。

关键词：生境质量评价主成分分析熵权法社会经济土地利用方式

新型C_(18)核壳结构色谱柱快速分析人参中的3种皂苷

在线全文

学校读者我要写书评

暂无评论

食品安全质量检测学报 2016年第7期7卷 2763-2769页

作者：岳焕新薛昆鹏金小青李良翔赵岳星浙江师范大学物理化学研究所金华321004 浙江月旭材料科技有限公司金华321014

目的建立高效液相色谱法(high performance liquid chromatography,HPLC)测定人参中人参皂苷Rg_1、Re和Rb_1 3种人参皂苷的含量。方法采用月旭Boltimate^(TM)C_(18)新型核壳色谱柱对3种人参皂苷进行分离,以乙腈-1.0%磷酸水溶液为流动相... 详细信息

目的建立高效液相色谱法(high performance liquid chromatography,HPLC)测定人参中人参皂苷Rg_1、Re和Rb_1 3种人参皂苷的含量。方法采用月旭Boltimate^(TM)C_(18)新型核壳色谱柱对3种人参皂苷进行分离,以乙腈-1.0%磷酸水溶液为流动相进行梯度洗脱,采用HPLC进行检测。结果 3种人参皂苷在月旭Boltimate^(TM)C_(18)新型核壳色谱柱能够快速分离,且分离效果较好。3种人参皂苷的在0.4~4.0μg质量浓度范围内呈良好的线性关系,线性相关系数(R^2)分别为0.9998,0.9996和0.9997;Rg_1、Re和Rb_1检出限分别为0.003、0.001和0.002μg/kg;加标回收率为98.3%~101.3%,相对标准偏差RSD分别为0.8%、1.1%和1.5%(n=6)。结论本方法具有快速、柱压低及节省溶剂等优势,可用于人参提取物中人参皂苷的测定。

关键词：人参人参皂苷高效液相色谱核壳色谱柱

Emerging CoMn-LDH@MnO2 electrode materials assembled using nanosheets for flexible and foldable energy storage devices

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2020年第6期29卷 67-73,I0003页

作者： yue zhao Jiafeng He Meizhen Dai Depeng zhao xiang Wu Baodan Liu School of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870LiaoningChina Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina

CoMn layered double hydroxides(CoMn-LDH)are promising electrode materials for supercapacitors because of their excellent cyclic ***,they possess relatively low *** this work,hybrid CoMn-LDH@MnO2 products grown on Ni foams were obtained through a facile hydrothermal *** as-synthesized samples employed as electrodes deliver a specific capacitance of 2325.01 F g^-1 at 1 A g^-*** assembled asymmetric supercapacitor using these products as positive electrodes shows a maximum energy density of 59.73 W h kg^-1 at 1000.09 W kg^-*** prominent electrochemical performance of the as-prepared electrodes could be attributes to hierarchical *** findings suggest that hybrid structures might be potential alternatives for future flexible energy storage devices.

关键词： CoMn-LDH@MnO2 electrode Specific capacitance Flexible device Cyclic stability

miRNAs在甲基苯丙胺成瘾中的作用研究进展

在线全文

学校读者我要写书评

暂无评论

中国药理学通报 2017年第8期33卷 1056-1060页

作者：何永旺李娟周一卿赵祥月杨根梦张柠曾晓锋李桢昆明医科大学法医学院云南昆明650500 中国医学科学院北京协和医学院医学生物学研究所云南省重大传染病疫苗研发重点实验室云南昆明650118

甲基苯丙胺(methamphetamine,METH)成瘾是机体长期接触METH后,中枢神经系统在分子、细胞、神经环路功能和脑结构等层次发生的代偿性适应,该过程有多种途径和多种机制共同参与。miRNAs作为一种新型基因转录后调控分子和突触的调节因子,... 详细信息

甲基苯丙胺(methamphetamine,METH)成瘾是机体长期接触METH后,中枢神经系统在分子、细胞、神经环路功能和脑结构等层次发生的代偿性适应,该过程有多种途径和多种机制共同参与。miRNAs作为一种新型基因转录后调控分子和突触的调节因子,大量存在于中枢神经系统,对中枢神经系统具有重要的调控作用。研究表明,miRNAs在METH成瘾中发挥着重要的调控作用。该文对miRNAs在METH成瘾机制中的表达特征及调控作用进行综述,并将与METH成瘾相关的miRNAs分子以及各miRNAs分子在不同组织器官中的差异性表达部位进行归纳整理,为进一步研究miRNAs分子在METH成瘾中的作用及发现新的药物作用靶点提供参考。

关键词：法医毒理学 microRNAs 甲基苯丙胺成瘾机制调控作用差异性表达研究进展