检索结果-南通市图书馆

Gut microbiota modulating intestinal stem cell differentiation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2024年第6期16卷 619-622页

作者： Lin He Chen Zhu xiang-feng zhou Shu-E Zeng Le Zhang Kuan Li Department of Alcohol and Drug Dependence Treatment The Mental Hospital of Yunnan ProvinceKunming 650224Yunnan ProvinceChina Department of Physical Education Kunming Medical UniversityKunming 650500Yunnan ProvinceChina Department of Geriatric Psychiatry The Mental Hospital of Yunnan ProvinceKunming 650224Yunnan ProvinceChina Sleep Medicine Center The Mental Hospital of Yunnan ProvinceKunming 650224Yunnan ProvinceChina

Proliferation and differentiation of intestinal stem cell(ISC)to replace damaged gut mucosal epithelial cells in inflammatory states is a critical step in ameliorating gut ***,when this disordered proliferation continues,it induces the ISC to enter a cancerous *** gut microbiota on the free surface of the gut mucosal barrier is able to interact with ISC on a sustained ***-biota metabolites are able to regulate the proliferation of gut stem and progenitor cells through transcription factors,while in steady state,differentiated colono-cytes are able to break down such metabolites,thereby protecting stem cells at the gut *** the future,the gut flora and its metabolites mediating the regulation of ISC differentiation will be a potential treatment for enteropathies.

关键词： Intestinal stem cells Gut microbiota Gut stem niche Microenvironment Probiotics

Experimental evidence of surface copper boride

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第7期16卷 9602-9607页

作者： Xiao-Ji Weng Jie Bai Jingyu Hou Yi Zhu Li Wang Penghui Li Anmin Nie Bo Xu xiang-feng zhou Yongjun Tian Center for High Pressure Science State Key Laboratory of Metastable Materials Science and TechnologySchool of ScienceYanshan UniversityQinhuangdao 066004China Key Laboratory of Weak-Light Nonlinear Photonics and School of Physics Nankai UniversityTianjin 300071China Vacuum Interconnected Nanotech Workstation Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China

To validate the crystal structure and elucidate the formation mechanism of the unexpected surface copper boride,a systematic scanning tunneling microscope,X-ray photoelectron spectroscopy,angle-resolved photoemission spectroscopy,and aberrationcorrected scanning transmission electron microscopy investigations were conducted to confirm the structure of copper-rich boride Cu_(8)B_(14)after depositing boron on single-crystal Cu(111)surface under ultrahigh ***-principles calculations with defective surface models further indicate that boron atoms tend to react with Cu atoms near terrace edges or defects,which in turn shapes the intermediate structures of copper boride and leads to the formation of stable Cu-B monolayer via large-scale surface reconstruction eventually.

关键词： copper boride surface science ultrahigh vacuum structure characterization first principles formation mechanism

Fermi Rubik's Cube in High-Pressure Induced Chlorine-Rich Compounds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2024年第10期41卷 78-83页

作者： Jun Kong Lei Su Haixu Cui Hairui Ding Jingyu Hou Chunxia Chi Shiyang Liu xiang-feng zhou Hui-Tian Wang Xiao Dong Key Laboratory of Weak-Light Nonlinear Photonics and School of Physics Nankai UniversityTianjin 300071China Center for High Pressure Science and Technology Advanced Research Beijing 100093China Key Laboratory of Photochemistry Institute of ChemistryUniversity of Chinese Academy of SciencesChinese Academy of SciencesBeijing 100190China College of Physics and Materials Science Tianjin Normal UniversityTianjin 300387China Center for High Pressure Science State Key Laboratory of Metastable Materials Science and TechnologySchool of ScienceYanshan UniversityQinhuangdao 066004China National Laboratory of Solid State Microstructures School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China

In the quasi-free electron model,the Fermi surface spreads into a sphere in the Brillouin zone,i.e.,the Fermi *** Fermi sphere exists widely in metal systems,no matter whether the crystal is in a body-center cubic,face-center cubic,or hexagonal close-packed ***,we report a class of compounds stabilized at high pressure with Rubik’s cubic Fermi surface.

关键词： surface. Fermi cubic

Phenotypic Heterogeneity in Cell Proliferation and Radiosensitivity in Human Laryngocarcinoma Hep-2 Cells

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

生物医学工程学杂志 2005年第S1期22卷 77-78页

作者： Guang HAN Chuang-Ying XIAO Fu-xiang zhou Yun-feng zhou~Δ Wen-Jie ZHANG(Department of Radio-Chemotherapy, Zhongnan Hospital, Cancer Research Center,Wuhan University, Wuhan 430071, China)

Formation of copper boride on Cu(111)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fundamental Research 2021年第4期1卷 482-487页

作者： Chengguang Yue Xiao-Ji Weng Guoying Gao Artem ROganov Xiao Dong Xi Shao Xiaomeng Wang Jian Sun Bo Xu Hui-Tian Wang xiang-feng zhou Yongjun Tian Center for High Pressure Science State Key Laboratory of Metastable Materials Science and TechnologySchool of ScienceYanshan UniversityQinhuangdao 066004China Key Laboratory of Weak-Light Nonlinear Photonics School of PhysicsNankai UniversityTianjin 300071China Skolkovo Institute of Science and Technology Skolkovo Innovation Center3 Nobel StreetMoscow 121025Russia National Laboratory of Solid State Microstructures Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China

Boron forms compounds with nearly all metals,with notable exception of copper and other group IB and IIB ***,we report an unexpected discovery of ordered copper boride grown epitaxially on Cu(111)under ultrahigh *** tunneling microscopy experiments combined with ab initio evolutionary structure prediction reveal a remarkably complex structure of 2D-Cu_(8)B_(14).Strong intra-layer p–d hybridization and a large amount of charge transfer between Cu and B atoms are the key factors for the emergence of copper *** makes the discovered material unique and opens up the possibility of synthesizing ordered low-dimensional structures in similar immiscible systems.

关键词： Molecular beam epitaxy Scanning tunneling microscopy Cu(111) Boron Copper boride

Chromatographic Separation and Characterization of Capsaicinoids and Their Analogues

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2011年第3期2卷 136-140页

作者： Jun-lian Wang Li zhou Lei Wang Zheng hong Peng Sheng ze zhou xiang feng zhou Xiao bin Zhang Bixian Peng 不详

An attempt was made to establish a chromatographic separation and analysis method for capsaicinoids and their analogues. A series of factors,such as choice of column and eluents, eluent composition,flow rate of eluent and operational temperature were correlated, countereacted and optimized to attain appropriate separation efficiency and finalize the experimentally oprational procedures as a whole, permiting a mixture comprising 8 capsaicinoids including analogues to be separated and Characterized with an allowed deviations and within a period of 36 minutes via 1 test as well.

关键词： Capsaicinoid Chromatography Separation Characterization

A Study of Pungency of Capsaicinoid as Affected by Their Molecular Structure Alteration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2011年第3期2卷 109-115页

作者： Jun-Lian WANG Zheng-hong PENG Sheng-ze zhou Jin-xi Zhang Song-fei Zhang xiang-feng zhou Xiao-bin ZHANG Bi-xian PENG Technical Institute of physics and Chemistry CAS Beijing China

An attempt was made in an effort to synthesize a series of capsaicinoids, most of which are synthesized in our laboratory and characterized to be completely new members of capsaicinoids. The Structure-pungency depende... 详细信息

关键词： Capsaicinoid Preparation Structure Pungency

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin zhou Dan Ma Yi-xiang He Jing Jin Hong-Lian Wang Yun-feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

Discovery of carbon-based strongest and hardest amorphous material

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2022年第1期9卷 25-35页

作者： Shuangshuang Zhang Zihe Li Kun Luo Julong He Yufei Gao Alexander V.Soldatov Vicente Benavides Kaiyuan Shi Anmin Nie Bin Zhang Wentao Hu Mengdong Ma Yong Liu Bin Wen Guoying Gao Bing Liu Yang Zhang Yu Shu Dongli Yu xiang-feng zhou Zhisheng Zhao Bo Xu Lei Su Guoqiang Yang Olga P.Chernogorova Yongjun Tian Center for High Pressure Science (CHiPS) State Key Laboratory of Metastable Materials Science and Technology Yanshan University Key Laboratory for Microstructural Material Physics of Hebei Province School of Science Yanshan University Department of Engineering Sciences and Mathematics Lule a University of Technology Department of Physics Harvard University Center for High Pressure Science and Technology Advanced Research Department of Materials Science Saarland University Key Laboratory of Photochemistry Institute of Chemistry University of Chinese Academy of Sciences Baikov Institute of Metallurgy and Materials Science Russian Academy of Sciences

Carbon is one of the most fascinating elements due to its structurally diverse allo tropic forms stemming from its bonding varieties(sp,sp~2 and sp~3).Exploring new forms of carbon has been the eternal theme of scientific ***,we report on amorphous(AM) carbon materials with a high fraction of sp~3 bonding recovered from compression of fullerene C60 under high pressure and high temperature,previously *** of photoluminescence and absorption spectra demonstrates that they are semiconducting with a bandgap range of 1.5-2.2 eV,comparable to that of widely used AM *** mechanical tests demonstrate that synthesized AM-Ⅲ carbon is the hardest and strongest AM material known to date,and can scratch diamond crystal and approach its *** produced AM carbon materials combine outstanding mechanical and electronic properties,and may potentially be used in photovoltaic applications that require ultrahigh strength and wear resistance.

关键词： amorphous carbon ultrahard ultrastrong semiconductor phase transition