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Weak type(1, 1) of the Riesz transform on some direct product manifolds with exponential volume growth

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Science China Mathematics 2024年第7期67卷 1599-1622页

作者： Hong-Quan Li Jie-xiang zhu School of Mathematical Sciences Fudan UniversityShanghai200433China Center for Applied Mathematics Tianjin UniversityTianjin300072China

In this paper, we are concerned with the Riesz transform on the direct product manifold H^(n)× M,where H^(n) is the n-dimensional real hyperbolic space, and M is a connected complete non-compact Riemannian manifold satisfying the volume doubling property and generalized Gaussian or sub-Gaussian upper estimates for the heat kernel. We establish its weak type(1, 1) property. In addition, we obtain the weak type(1, 1) of the heat maximal operator in the same setting. Our arguments also work for a large class of direct product manifolds with exponential volume growth. Particularly, we provide a simpler proof of weak type(1, 1) boundedness of some operators considered in the work of Li et al.(2016).

关键词： Riesz transform heat kernel direct product real hyperbolic space

Transcription factor OsSPL10 interacts with OsJAmyb to regulate blast resistance in rice

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The Crop Journal 2024年第1期12卷 301-307页

作者： Zaofa Zhong Lijing Zhong xiang zhu Yimin Jiang Yihong Zheng Tao Lan Haitao Cui College of Life Science Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Fujian Provincial Key Laboratory of Crop Breeding by Design Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina College of Plant Protection Shandong Agricultural UniversityTai’an 271018ShandongChina

Transcription factors(TFs)play essential roles in transcriptional reprogramming during activation of plant immune responses to ***10(SQUAMOSA promoter binding protein-like10)is an important TF regulating trichome development and salt tolerance in *** we report that knockout of OsSPL10 reduces whereas its overexpression enhances rice resistance to blast ***10 positively regulates chitin-induced immune responses including reactive oxygen species(ROS)burst and callose *** show that OsSPL10 physically associates with OsJAmyb,an important TF involved in jasmonic acid(JA)signaling,and positively regulates its protein *** then prove that OsJAmyb positively regulates resistance to *** results reveal a molecular module consisting of OsSPL10 and OsJAmyb that positively regulates blast resistance.

关键词： Immunity Jasmonate Oryza sativa OsSPL10 Transcription factor

Research on Pulsar Time Steered Atomic Time Algorithm Based on DPLL

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Research in Astronomy and Astrophysics 2024年第3期24卷 237-248页

作者： Ze-Hao Zheng Yang Liu Dan Shen Fan Feng Jiu-Long Liu Yue-Xin Ma xiang-Wei zhu School of Electronic and Communication Engineering Sun Yat-sen UniversityShenzhen 518107China School of Aeronautics and Astronautics Sun Yat-sen UniversityShenzhen 518107China School of Systems Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China

In today’s society,there is a wide demand for high-precision and high-stability time service in the fields of electric power,communication,transportation and *** present,the time standard in various countries is mainly based on atomic clocks,but the frequency drift of atomic clocks will affect the long-term stability *** with atomic clocks,millisecond pulsars have better long-term stability and can complement with the excellent short-term stability of atomic *** order to improve the long-term stability of the atomic timescale,and then improve the timing accuracy,this paper proposes an algorithm for steering the atomic clock ensemble(ACE)by ensemble pulsar time(EPT)based on digital phase locked loop(DPLL).First,the ACE and EPT are generated by the ALGOS algorithm,then the ACE is steered by EPT based on DPLL to calibrate the long-term frequency drift of the atomic clock,so that the generated steered atomic time follows both the short-term stability characteristics of ACE and the long-term stability characteristics of EPT,and finally,the steered atomic time is used to calibrate the local cesium *** experimental results show that the long-term stability of atomic time after steering is improved by 2 orders of magnitude compared with that before steering,and the daily drift of a local cesium clock after calibration is less than 9.47 ns in 3 yr,3 orders of magnitude higher than that before calibration on accuracy.

关键词： (stars) pulsars general-time-methods data analysis-instabilities

Rational Synthesis of Crystalline Covalent Triazine Framework with Methylthio Pendant Arms for Efficient Mercury(Ⅱ)Adsorption

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分子催化（中英文） 2024年第4期38卷 309-316页

作者： LOU Yi-xiao ZHOU Lu-lu YANG Na zhu xiang State Key Laboratory for Oxo Synthesis and Selective Oxidation Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China School of Resources and Environment Engineering East China University of Science and TechnologyShanghai 200237China

The interest in curtailing environmental pollution issues through physical separation processes has inspired an extensive search for novel nanoporous materials with exceptional adsorption *** triazine frameworks(CTFs),emerged as a class of crystalline covalent organic frameworks(COFs),have been widely examined for various separation applications,owing to their large porosity,high stability,and rich nitrogen(N)*** development of CTFs for efficient adsorption of mercury(Ⅱ)(Hg^(2+))is of great importance for the field,whereas it is rarely attempted,on account of limited synthetic strategies and unknown structural-property relations of conventional CTFs derived from ionothermal ***,we report rational synthesis of a crystalline CTF with methylthio pendant arms for efficient removal of Hg^(2+)with an exceptional capacity of 751 mg·g^(-1),ranking at the top among previously-reported *** work may open up new possibility in the synthesis of COFs for various separations.

关键词： CTFs methylthio pendant arms mercury adsorption structural-property relationship

Dangling Ligand Enables an Iron Hexa-Coordinated Molecular Catalyst for Water Oxidation by Photocatalysis

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CCS Chemistry 2024年第3期6卷 623-630页

作者： Bing Yang Qi Liu xiang-zhu Wei Tao Lei Qing-Qing Yang Xu-Zhe Wang Jing-Xin Jian Xin Jiang Chen-Ho Tung Li-zhu Wu Key Laboratory of Photochemical Conversion and Optoelectronic Materials New Cornerstone Science LaboratoryTechnical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190 School of Future Technology University of Chinese Academy of SciencesBeijing 100049

Photocatalytic water oxidation reaction by transition metal complexes remains a challenge because of their poor stability under irradiation,especially for earth-abundant metal *** this regard,ironbased water oxidation catalysts are prone to hydrolysis and/or dissociate the ligands to form nanoparticles under a real catalytic ***,we describe a unique hexa-coordinated catalyst 1[Fe^(II)(Py_(3)tacn)Cl_(2)]and its reference 2[Fe^(II)(PhPy_(2)tacn)Cl_(2)]with a dangling pyridyl ligand and a phenyl group,*** anticipated that the dynamically open and close coordination behaviors of the pyridyl ligand enabled balance of the reactivity and stability of catalyst *** our delight,the“open form”of catalyst 1 provided a free coordination site,and the“close form”guaranteed its molecular integrity,resulting in a water oxidation reaction with high efficiency and *** turnover number and turnover frequency values of 2332 and 60 s^(−1)are the highest known to date among iron-based homogeneous water oxidation systems under visible light irradiation.

关键词： water oxidation photocatalysis homogeneous catalysis iron complexes dangling ligand intermediates characterization

High patatin like phospholipase domain containing 8 expression as a biomarker for poor prognosis of colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 787-797页

作者： Peng-Yang Zhou De-xiang zhu Yi-Jiao Chen Qing-Yang Feng Yi-Hao Mao Ao-Bo zhuang Jian-Min Xu Department of General Surgery Zhongshan Hospital Fudan UniversityShanghai 200032China

BACKGROUND Patatin like phospholipase domain containing 8(PNPLA8)has been shown to play a significant role in various cancer *** studies have focused on its roles as an antioxidant and in lipid ***,the role of PNPLA8 in colorectal cancer(CRC)progression is *** To explore the prognostic effects of PNPLA8 expression in *** A retrospective cohort containing 751 consecutive CRC patients was ***8 expression in tumor samples was evaluated by immunohistochemistry staining and semi-quantitated with immunoreactive *** patients were divided into high and low PNPLA8 expression groups based on the cut-off va-lues,which were calculated by X-tile *** prognostic value of PNPLA8 was identified using univariate and multivariate Cox regression *** over-all survival(OS)rates of CRC patients in the study cohort were compared with Kaplan-Meier analysis and Log-rank *** PNPLA8 expression was significantly associated with distant metastases in our cohort(P=0.048).CRC patients with high PNPLA8 expression indicated poor OS(median OS=35.3,P=0.005).CRC patients with a higher PNPLA8 expression at either stage I and II or stage III and IV had statistically significant shorter *** patients with left-sided colon and rectal cancer,the survival curves of two PN-PLA8-expression groups showed statistically significant *** analysis also confirmed that high PNPLA8 expression was an independent prog-nostic factor for overall survival(hazard ratio HR=1.328,95%CI:1.016-1.734,P=0.038).

关键词： Biomarker Colorectal cancer Expression level Overall survival Patatin like phospholipase domain containing 8 Prognosis

基于空间模拟的都市圈旅游景区综合交通可达性分析——以长株潭都市圈为例

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旅游学刊 2024年第1期39卷 130-146页

作者：朱政朱翔湖南师范大学美术学院环境设计系湖南长沙410081 湖南师范大学地理科学学院湖南长沙410081

综合交通可达性对当代都市圈的旅游景区服务质量和游客体验有重要作用。文章以长株潭都市圈为例,通过空间数据库构建、出发点玫瑰图构建、交通分担率测算、交通接驳时间计算、交通方式可达性分析、景区综合交通可达性结构分析等空间模... 详细信息

综合交通可达性对当代都市圈的旅游景区服务质量和游客体验有重要作用。文章以长株潭都市圈为例,通过空间数据库构建、出发点玫瑰图构建、交通分担率测算、交通接驳时间计算、交通方式可达性分析、景区综合交通可达性结构分析等空间模拟步骤,深入归纳其旅游景区综合交通可达性的空间分布特征及问题。结果表明:长株潭都市圈中旅游景区综合交通可达性的空间分布呈现出由中心城区向边缘区域的“低-高-低”趋势。旅游景区对高速公路依赖显著,轨道交通作用发挥不足,各类交通之间接驳不畅,部分景区入口设计存在问题。文章据此提出宏观交通规划、中观交通组织、微观交通设计3方面的优化措施。文章通过对旅游交通的前端、中端、末端环节全过程分析,构建都市圈旅游景区综合交通可达性的研究框架。在交旅融合背景下,对于优化都市圈的旅游交通系统具有规划和管理的启发作用。

关键词：旅游景区综合交通可达性长株潭都市圈空间模拟

CR400BF平台动车组牵引系统可靠性评估

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铁道机车车辆 2024年第3期44卷 139-145页

作者：朱湘中国铁道科学研究院研究生部北京100081 中国铁路上海局集团有限公司上海动车段上海201812

对高级修周期间隔延长背景下的CR400BF平台动车组牵引系统进行可靠性评估。基于牵引系统的部件结构及基本的系统组合形式,构建可靠性框图模型;收集整理动车组运营过程中的故障数据,利用直方图法对故障分布模型进行初步判断;通过假定分... 详细信息

对高级修周期间隔延长背景下的CR400BF平台动车组牵引系统进行可靠性评估。基于牵引系统的部件结构及基本的系统组合形式,构建可靠性框图模型;收集整理动车组运营过程中的故障数据,利用直方图法对故障分布模型进行初步判断;通过假定分布模型的参数估计及拟合优度检验,确定各部件的故障分布规律;评估牵引系统各部件及其整体的可靠性指标,绘制可靠度函数图形并进行简要分析。文中所用的分析方法具有较好的通用性,可以进一步推广到动车组其他系统,能够为动车组修程修制改革提供技术支撑。

关键词： CR400BF 动车组牵引系统可靠性修程修制故障

Effect of dapagliflozin on uric acid in patients with chronic heart failure and hyperuricemia

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World Journal of Clinical Cases 2024年第18期12卷 3468-3475页

作者： Meng-Jiao Lin Shu-Bin Zou Bai-xiang zhu Three departments of cardiovascular medicine Harbin 242 HospitalHarbin 150066Heilongjiang ProvinceChina

BACKGROUND Patients with chronic heart failure(CHF)frequently develop hyperuricemia,an elevated serum uric acid level,associated with adverse ***,a sodium-glucose cotransporter-2 inhibitor,demonstrates reduction in cardiovascular mortality and hospitalization in patients with CHF and ejection fraction(HFrEF),irrespective of ***,dapagliflozin’s effect on the uric acid levels in patients with CHF and hyperuricemia remain *** To investigate the effects of dapagliflozin on uric acid levels in CHF patients with *** We conducted a randomized,double-blind,placebo-controlled trial in 200 patients with CHF and hyperuricemia,with HFrEF and serum uric acid levels≥7 mg/dL(≥416μmol/L).The participants were randomly assigned to receive a daily dose of 10 mg dapagliflozin or placebo for 24 *** primary endpoint was the change in serum uric acid level from baseline to 24 *** endpoints included changes in left ventricular ejection fraction(LVEF),Nterminal pro-B-type natriuretic peptide(NT-proBNP),and quality of life(QoL)scores,as well as the incidence of cardiovascular death and hospitalization for heart *** At 24 months,dapagliflozin significantly reduced serum uric acid levels by 1.2 mg/dL(71μmol/L)compared with placebo(95%CI:-1.5 to-0.9;P<0.001).Dapagliflozin also significantly improved LVEF by 3.5%(95%CI:2.1-4.9;P<0.001),NT-proBNP by 25%(95%CI:18-32;P<0.001),and QoL scores by 10 points(95%CI:7-13;P<0.001)and reduced the risk of cardiovascular death and hospitalization for heart failure by 35%(95%CI:15–50;P=0.002)compared with the *** events were similar between the two groups,except for a higher rate of genital infections in the dapagliflozin group(10%vs 2%,P=0.01).CONCLUSION Dapagliflozin significantly lowered serum uric acid levels and improved the clinical outcomes in patients with CHF and ***,dapagliflozin may be a useful therapeutic option for this high-r

关键词： Dapagliflozin Hyperuricemia Chronic heart failure Sodium-glucose cotransporter-2 inhibitor Uric acid levels Cardiovascular mortality