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The spectrum and stability of travelling pulses in a coupled FitzHugh-Nagumo equation

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Science China Mathematics 2024年第5期67卷 975-1010页

作者： Qi Qiao xiang zhang School of Mathematical Sciences Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Scientific and Engineering Computing(Ministry of Education) and Shanghai Frontier Science Center of Modern Analysis(CMA-Shanghai)Shanghai Jiao Tong UniversityShanghai 200240China

For a coupled slow-fast FitzHugh-Nagumo(FHN)equation derived from a reaction-diffusionmechanics(RDM)model,Holzer et al.(2013)studied the existence and stability of the travelling pulse,which consists of two fast orbit arcs and two slow ones,where one fast segment passes the unique fold point with algebraic decreasing and two slow ones follow normally hyperbolic critical curve *** and zhang(2021)obtained the existence of the travelling pulse,whose two fast orbit arcs both exponentially decrease,and one of the slow orbit arcs could be normally hyperbolic or not at the ***,we characterize both the nonlinear and spectral stability of this travelling pulse.

关键词： coupled FitzHugh-Nagumo equation singular perturbation travelling pulse spectrum nonlinear stability spectral stability

E-MobileNeXt: face expression recognition model based on improved MobileNeXt

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Optoelectronics Letters 2024年第2期20卷 122-128页

作者： zhang xiang YAN Chunman School of Physics and Electronic Engineering Northwest Normal UniversityLanzhou 730070China1

In response to the high complexity and low accuracy of current facial expression recognition networks, this paper proposes an E-Mobile Ne Xt network for facial expression recognition. E-Mobile Ne Xt is built based on our proposed E-Sand Glass block. In addition, we also improve the overall performance of the network through Rep Conv and SGE attention mechanisms. The experimental results show that the network model improves the expression recognition accuracy by 6.5% and 7.15% in RAF-DB and CK+ datasets, respectively, while the parameter and floating-point operations decreased by 0.79 M and 4.2 M compared with Mobile Ne Xt.

关键词： facial mechanisms. network

Probiotics intervention in colorectal cancer:From traditional approaches to novel strategies

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Chinese Medical Journal 2024年第1期137卷 8-20页

作者： Suki Ha xiang zhang Jun Yu Institute of Digestive Disease and Department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesThe Chinese University of Hong KongHong Kong SARChina

The intestine harbors a large population of microorganisms that interact with epithelial cells to maintain host healthy physiological *** intestinal microbiota engage in the fermentation of non-digestible nutrients and produce beneficial metabolites to regulate host homeostasis,metabolism,and immune *** disruption of microbiota,known as dysbiosis,has been implicated in many intestinal diseases,including colorectal cancer(CRC).As the third most common cancer and the second leading cause of cancer-related death worldwide,CRC poses a significant health *** is an urgent need for novel interventions to reduce CRC incidence and improve clinical *** the intestinal microbiota has emerged as a promising approach for CRC prevention and *** research efforts in CRC probiotics primarily focus on reducing the incidence of CRC,alleviating treatment-related side effects,and potentiating the efficacy of anticancer therapy,which is the key to successful translation to clinical *** paper aims to review the traditional probiotics and new interventions,such as next-generation probiotics and postbiotics,in the context of *** underlying mechanisms of probiotic anti-cancer effects are also discussed,including the restoration of microbial composition,reinforcement of gut barrier integrity,induction of cancer cell apoptosis,inactivation of carcinogens,and modulation of host immune *** paper further evaluates the novel strategy of probiotics as an adjuvant therapy in boosting the efficacy of chemotherapy and *** all the promising findings presented in studies,the evaluation of potential risks,optimization of delivery methods,and consideration of intra-patient variability of gut microbial baseline must be thoroughly interpreted before bench-to-bedside translation.

关键词： colorectal cancer probiotics gut microbiota dysbiosis adjuvant therapy immune modulation gut barrrier

Capacity Market Mechanism Design,Considering Network Optimization and Energy Transition

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CSEE Journal of Power and Energy Systems 2024年第4期10卷 1676-1687页

作者： Nan Shang Yihang Song xiang zhang You Lin China Southern Power Grid Co. Ltd.Guangzhou 510663China Southern Methodist University Junkins 3086251 Airline Road DallasTX 75205US

The coordination of enrgy transition,fixed cost recovery,and sufficient generation supply leads to a new challenge for a traditional capacity market ***,in order to better match network expansion at the same time,it is crucial to redesign the capacity market mechanism considering system *** this paper,a novel capacity market mechanism is proposed considering spot market operations,network expansion,and energy transition,which can minimize the total cost of capacity investment,network expansion,and generation operations,while satisfying the energy transition constraints and topology ***,the capacity market mechanism co-ordinated with spot market operations is illustrated,in which the energy transition and network constraints are ***,a bi-level optimization model is established where the trade organizers minimize the total cost of both investment and operations,subject to the spot power market simultaneously minimizing the local dispatching *** numerical results of a test system show that more economical capacity portfolios can be obtained by constructing reasonable transmission lines,thereby obtaining a more optimal market cost.A detailed multi-scenario simulation is further analyzed to verify the effectiveness of the proposed market mechanism.

关键词： Capacity market energy transition network expansion spot market operation

Influence of pressure disturbance wave on dynamic response characteristics of liquid film seal for multiphase pump

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Petroleum Science 2024年第3期21卷 2048-2065页

作者： Qing-Ping Li Jin-Ya zhang Jia-xiang zhang Yong-Xue zhang CNOOC Research Institute Company Limited Beijing100028China State Key Laboratory of Natural Gas Hydrate Beijing100028China College of Mechanical and Transportation Engineering China University of PetroleumBeijing2249China

Slug flow or high GVF(Gas Volume Fraction)conditions can cause pressure disturbance waves and alternating loads at the boundary of mechanical seals for multiphase pumps,endangering the safety of multiphase pump *** mechanical seal model is simplified by using periodic boundary conditions and numerical calculations are carried out based on the Zwart-Gerber-Belamri cavitation ***(User Define Function)programs such as structural dynamics equations,alternating load equations,and pressure disturbance equations are embedded in numerical calculations,and the dynamic response characteristics of mechanical seal are studied using layered dynamic mesh *** results show that when the pressure disturbance occurs at the inlet,as the amplitude and period of the disturbance increase,the film thickness gradually *** the fundamental reason for the hysteresis of the film thickness change is that the pressure in the high-pressure area cannot be restored in a timely *** maximum value of leakage and the minimum value of axial velocity are independent of the disturbance period and determined by the disturbance *** mutual interference between enhanced waves does not have a significant impact on the film thickness,while the front wave in the attenuated wave has a promoting effect on the subsequent film thickness changes,and the fluctuation of the liquid film cavitation rate and axial velocity under the attenuated wave condition deviates from the initial *** with pressure disturbance conditions,alternating load conditions have a more significant impact on film thickness and *** actual operation,it is necessary to avoid alternating load conditions in multiphase pump mechanical seals.

关键词： Multiphase pump Liquid film seal Pressure disturbance wave Dynamic response characteristics

Bile acids,gut microbiota,and therapeutic insights in hepatocellular carcinoma

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Cancer Biology & Medicine 2024年第2期21卷 144-162页

作者： Yang Song Harry CH Lau xiang zhang Jun Yu Institute of Digestive Disease and Department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesCUHK Shenzhen Research InstituteThe Chinese University of Hong KongHong KongChina Department of Gastroenterology Zhongshan Hospital Xiamen UniversityXiamen 361004China

Hepatocellular carcinoma(HCC)is a prevalent and aggressive liver *** interplay between bile acids(BAs)and the gut microbiota has emerged as a critical factor in HCC development and *** normal conditions,BA metabolism is tightly regulated through a bidirectional interplay between gut microorganisms and *** gut microbiota plays a critical role in BA metabolism,and BAs are endogenous signaling molecules that help maintain liver and intestinal *** note,dysbiotic changes in the gut microbiota during pathogenesis and cancer development can disrupt BA homeostasis,thereby leading to liver inflammation and fibrosis,and ultimately contributing to HCC ***,understanding the intricate interplay between BAs and the gut microbiota is crucial for elucidating the mechanisms underlying *** this review,we comprehensively explore the roles and functions of BA metabolism,with a focus on the interactions between BAs and gut microorganisms in ***,therapeutic strategies targeting BA metabolism and the gut microbiota are discussed,including the use of BA agonists/antagonists,probiotic/prebiotic and dietary interventions,fecal microbiota transplantation,and engineered *** summary,understanding the complex BA-microbiota crosstalk can provide valuable insights into HCC development and facilitate the development of innovative therapeutic approaches for liver malignancy.

关键词： Bile acid gut microbiota hepatocellular carcinoma therapeutics microbiota modulation

Comparative evaluation of SPE methods for biotoxicity assessment of water and wastewater:Linkage between chemical extracting efficiency and biotoxicity outcome

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Journal of Environmental Sciences 2024年第8期142卷 33-42页

作者： Jiawei Zhou Shihao Wang Xiwei He Hongqiang Ren Xu-xiang zhang State Key Laboratory of Pollution Control and Resource Reuse School of EnvironmentNanjing UniversityNanjing 210023China

Biotoxicity assessment results of environmental waters largely depend on the sample extraction protocols that enrich pollutants to meet the effect-trigger thresholds of ***,more chemical mixture does not necessarily translate to higher combined ***,there is a need to establish the link between chemical extracting efficiency and biotoxicity outcome to standardize extraction methods for biotoxicity assessment of environmental *** study compares the performance of five different extraction phases in solid phase extraction(SPE),namely HLB,HLB+Coconut,C18 cartridge,C18 disk and Strata-X,and evaluated their chemical extracting efficiencies and biotoxicity *** quantitatively assessed cytotoxicity,acute toxicity,genotoxicity,estrogenic activity,and neurotoxicity of the extracts using in vitro bioassays and characterized the chemical extracting efficiencies of the SPE methods through chemical recoveries of 23 model compounds with different polarities and total organic *** Pareto ranking,we identified HLB+Coconut as the optimal SPE method,which exhibited the highest level of water sample biotoxicity and recovered the most chemicals in water *** found that the biotoxicity outcomes of the extracted water samples significantly and positively correlated with the chemical extracting efficiencies of the SPE ***,we observed synchronous changing patterns in biotoxicity outcome and chemical extracting efficiencies in response to increasing sample volumes per cartridge(SVPC)during *** findings underscore that higher chemical extracting efficiency of SPE corresponds to higher biotoxicity outcome of environmental water samples,providing a scientific basis for standardization of SPE methods for adequate assessment of biotoxicities of environmental waters.

关键词： Biotoxicity Chemical recovery Solid phase extraction Surface water Wastewater

Energy Absorption by 3D-Printed Mesh Structures with a Negative Poisson’s Ratio

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 205-212页

作者： Wenyu Li Weiming Yang Mingze Li xiang zhang Ping zhang Yucheng Zhao Peijian Chen Haishun Liu School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou221116China School of Materials Sciences and Physics China University of Mining and TechnologyXuzhou221116China

A negative Poisson's ratio(NPR)structure represents optimal impact-resistance with applications in various fields,including the crash box in vehicles,which absorbs impact kinetic *** crash box is designed to deform in response to impact,increasing local structural density,which enhances impact resistance *** studies have only focused on the NPR effect in the plane dimension at low-speed *** studies have considered high-speed impact loads on three-dimensional NPR *** have developed two types of AlSi10Mg alloy energy-absorbing structures with NPR using three-dimensional printing technology,and have compared our systems with a conventional hexagonal mesh *** testing involved split-Hopkinson pressure bar measurements,which showed good agreement with dynamic numerical *** subjected to an impact load,the NPR structure exhibited better impact resistance and energy absorption compared with the positive Poisson's ratio *** proposed dual-layer hexagonal structure ensures an NPR effect while exhibiting higher strength and improved stability relative to the conventional concave hexagon structure.

关键词： Negative Poisson’s ratio Energy absorption 3D printing Split-Hopkinson pressure bar Numerical simulation

Fabrication of corrosion inhibiting microcapsules functional coating and their high-efficiency corrosion resistance

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Rare Metals 2024年第2期43卷 842-848页

作者： Hao-Ran Yun Lu Lu Xue-Long Hao Xing-xiang zhang School of Material Science and Engineering Tiangong UniversityTianjin300387China National Center of Analysis and Testing for Nonferrous Metals and Electronic Materials General Research Institute for Nonferrous MetalsBeijing100088China Guobiao(Beijing)Testing&Certification Co. Ltd.Beijing101407China

Benzotriazole(BTA)was loaded into calcium carbonate microsphere shell by self-assembly method and a new type of high-efficiency corrosion inhibiting microcapsules(CIMs)were fabricated,which were added and dispersed into epoxy resin coating to obtain a new corrosion resistance functional *** corrosion inhibition effect of benzotriazole on aluminum alloy matrix was verified by polarization curve *** effectiveness of the CIMs and their loading capacity on inhibitor were evaluated by scanning electron microscope,laser confocal Raman spectroscopy together with thermogravimetric analysis.

关键词： corrosion coating resistance