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Controllability Gramian-based measures of graph product networks

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Science China(Information Sciences) 2024年第10期67卷 315-331页

作者： Yuequan xiang Linying xiang School of Information Science and Engineering Northeastern University School of Artificial Intelligence Tiangong University

This paper addresses the controllability measures of composite networks based on graph products, in which the graph product networks are either Kronecker product networks or Kronecker sum *** primary objective pursued here is to reveal the controllability Gramian-based measure links between the graph product composite network and its subnetworks. First, the analytical expression of the average controllability for the Kronecker product network is derived by using the corresponding controllability measures of its subnetworks. An upper bound of volumetric control energy is further obtained for the Kronecker product network. Then, the upper bounds are derived for the controllability measures of the Kronecker sum network,which provide a valuable reference for designing controllable networks in practical applications. Finally, the controllability of the Kronecker product network is compared with that of the Kronecker sum network, and it is found that when the subnetworks satisfy certain conditions, the Kronecker product network has better average controllability than the Kronecker sum network.

关键词： composite network graph product controllability Gramian-based measure average controllability control energy

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基于光纤四波混频效应的新型组播方法

物理学报 2008年第12期57卷 7699-7704页

作者：苗向蕊高士明高莹浙江大学光及电磁波研究中心现代光学仪器国家重点实验室杭州310058

组播是波长路由光通信网络中的一项重要功能.提出并实验实现了基于高非线性光纤四波混频效应的全光组播方法,将一束载有数据的输入信号光和一束抽运光一起入射到一段高非线性光纤中,通过两个简并四波混频过程产生了两个携带该数据信息... 详细信息

组播是波长路由光通信网络中的一项重要功能.提出并实验实现了基于高非线性光纤四波混频效应的全光组播方法,将一束载有数据的输入信号光和一束抽运光一起入射到一段高非线性光纤中,通过两个简并四波混频过程产生了两个携带该数据信息的闲频光,从而实现了单一信号的两信道组播,同时抽运光也会受到数据信息的调制.该方法的优点在于组播的实现只需要单一的抽运光源,而不需要再提供其他输入光,结构简单,组播光信号功率均匀、波长可调,并且具有进一步增加组播信道的能力.

关键词：组播四波混频高非线性光纤

Highβ-sitosterol-D-glucoside content in sweet potato varieties and its anti-breast cancer potential through multiple metastasis-associated signals

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Food Science and Human Wellness 2024年第5期13卷 2779-2789页

作者： Jinyin Zhang Lu Huang xiang Tang miao Pan Xiaoli Ye Xuegang Li Hang Ma School of Pharmaceutical Sciences Southwest UniversityChongqing 400716China School of Life Sciences Southwest UniversityChongqing 400715China

β-Sitosterol-D-glucoside(β-SDG)is a phytosterol compound whose antitumor activity has been confirmed by previous ***,its suppression on breast cancer remains *** that purpose,we isolatedβ-SDG from sweet potato and investigated the breast-cancer-inhibiting mechanism using proteomic *** sweet potato species S6 with highβ-SDG content were chosen form 36 species andβ-SDG was isolated by ***,an in situ animal model of breast cancer was established,andβ-SDG significantly reduced the tumor volume of MCF-7 xenograft *** analysis of tumor tissues revealed that 127 of these proteins were upregulated and 80 were *** ontology and network analysis showed that regulatory proteins were mainly associated with epithelial-mesenchymal transition(EMT),myogenesis,cholesterol homeostasis,oxidative phosphorylation and reactive oxygen pathways,while Vimentin,NDUF,VDAC1,PPP2CA and SNx9 were the most significant 5 node degree ***,in vitro and in vivo results showed that the protein expression of PPP2CA and Vimentin,which are markers of EMT,were involved in breast cancer cell metastasis and could be reversed byβ-*** work highlightsβ-SDG as a bioactive compound in sweet potato and the potential therapeutic effect ofβ-SDG for the treatment of breast cancer by inhibiting metastasis.

关键词： β-Sitosterol-D-glucoside(β-SDG) Sweet potato Breast cancer Proteomic Metastasis

Dual-ion carrier storage through Mg^(2+) addition for high-energy and long-life zinc-ion hybrid capacitor

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International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 179-185页

作者： Junjie Zhang xiang Wu School of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China

Cation additives can efficiently enhance the total electrochemical capabilities of zinc-ion hybrid capacitors (ZHCs).However their energy storage mechanisms in zinc-based systems are still under ***,we modulate the electrolyte and achieve dual-ion storage by adding magnesium *** we assemble several Zn//activated carbon devices with different electrolyte concentrations and investigate their electrochemical reaction dynamic *** zinc-ion capacitor with Mg^(2+)mixed solution delivers 82 mAh·g^(-1)capacity at 1 A·g^(-1) and maintains 91%of the original capacitance after 10000 *** is superior to the other assembled zinc-ion devices in single-component *** finding demonstrates that the double-ion storage mechanism enables the superior rate performance and long cycle lifetime of ZHCs.

关键词： zinc-ion hybrid capacitor MgSO_(4) electrolyte rate performance storage mechanism

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转基因动物新技术研究进展

遗传 2011年第5期33卷 449-458页

作者：罗庆苗苗向阳张瑞杰中国农业科学院北京畜牧兽医研究所北京100193

转基因技术经过数十年的发展日渐成熟,并推动转基因技术研究进入一个新的发展阶段。文章综述了体细胞核移植技术、慢病毒载体法、转座子介导的基因转移法、RNA干扰介导的基因敲除法和锌指核酸酶-基因打靶技术等近年发展起来的方法。而... 详细信息

转基因技术经过数十年的发展日渐成熟,并推动转基因技术研究进入一个新的发展阶段。文章综述了体细胞核移植技术、慢病毒载体法、转座子介导的基因转移法、RNA干扰介导的基因敲除法和锌指核酸酶-基因打靶技术等近年发展起来的方法。而近来诱导多能干细胞(iPS细胞)的成功为尚未获得ES细胞的大动物建立多能干细胞系提供了一种新的方案,为转基因动物研究开创一片更广阔的天地。文章在前人研究的基础上重点总结了以上各种转基因技术的最新研究动态并对各种转基因技术的特点进行了探讨。

关键词：转基因技术 RNAi 基因打靶锌指核酸酶 iPS 动物克隆

Modifying the Electron Dynamics in High-Order Harmonic Generation via a Two-Color Laser Field

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Chinese Physics Letters 2023年第12期40卷 40-45页

作者：张彩萍苗向阳 College of Physics and Information Engineering Shanxi Normal UniversityTaiyuan 030031China Key Laboratory of Spectral Measurement and Analysis of Shanxi Province Shanxi Normal UniversityTaiyuan 030031China

We investigate the harmonic emission from bichromatic periodic potential by numerically solving the timedependent Schro¨dinger equation in the velocity gauge. The results show that the harmonic minimum is sensitive to the wavelength. Moreover, distinct crystal momentum states contribute differently to harmonic generation. In momentum space, the electron dynamics reveal a close relationship between the spectral minimum and the electron distribution in higher conduction bands. Additionally, by introducing an ultraviolet pulse to the fundamental laser field, the suppression of the harmonic minimum occurs as a result of heightened electron populations in higher conduction bands. This work sheds light on the harmonic emission originating from a solid with a two-atom basis.

关键词： harmonic momentum bands

Cumulative effects of excess high-normal alanine aminotransferase levels in relation to new-onset metabolic dysfunction-associated fatty liver disease in China

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World Journal of Gastroenterology 2024年第10期30卷 1346-1357页

作者： Jing-Feng Chen Zhuo-Qing Wu Hao-Shuang Liu Su Yan You-xiang Wang miao Xing Xiao-Qin Song Su-Ying Ding Health Management Center The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Institute of Systems Engineering Dalian University of TechnologyDalian 116024Liaoning ProvinceChina College of Public Health Zhengzhou UniversityZhengzhou 450001Henan ProvinceChina School of Basic Medicine and Forensic Medicine Henan University of Science and TechnologyLuoyang 471003Henan ProvinceChina

BACKGROUND Within the normal range,elevated alanine aminotransferase(ALT)levels are associated with an increased risk of metabolic dysfunction-associated fatty liver disease(MAFLD).AIM To investigate the associations between repeated high-normal ALT measurements and the risk of new-onset MAFLD *** A cohort of 3553 participants followed for four consecutive health examinations over 4 years was *** incidence rate,cumulative times,and equally and unequally weighted cumulative effects of excess high-normal ALT levels(ehALT)were *** proportional hazards regression was used to analyse the association between the cumulative effects of ehALT and the risk of new-onset *** A total of 83.13%of participants with MAFLD had normal ALT *** incidence rate of MAFLD showed a linear increasing trend in the cumulative ehALT *** with those in the low-normal ALT group,the multivariate adjusted hazard ratios of the equally and unequally weighted cumulative effects of ehALT were 1.651[95%confidence interval(CI):1.199-2.273]and 1.535(95%CI:1.119-2.106)in the third quartile and 1.616(95%CI:1.162-2.246)and 1.580(95%CI:1.155-2.162)in the fourth quartile,*** Most participants with MAFLD had normal ALT ***-term high-normal ALT levels were associated with a cumulative increased risk of new-onset MAFLD.

关键词： Metabolic dysfunction-associated fatty liver disease High-normal alanine aminotransferase level Cumulative effect Cox proportional hazards regression Cohort study

Cytokine-induced killer cell combination with TACE in the treatment of hepatocellular cancers:a meta-analysis

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The Chinese-German Journal of Clinical Oncology 2013年第10期12卷 459-467页

作者： Biao Chen Ximing Xu miao xiang Jiao Yang Tingting Yu Yi Hu Cancer Center Renmin Hospital of Wuhan University

Objective：The aim of the study was to evaluate the ef icacy and safety of cytokine-induced kil er （CIK） cellcombined with transcatheter arterial chemoembolization （TACE） therapy in the treatment of hepatocellular carcinoma （HCC）. Methods：Randomized control ed trials （RCTs） on CIK cells combination with TACE based-therapy were identified by elec-tronic searches in the Cochrane Library, MEDLINE, Pubmed, Wanfang, VIP, CNKI and other electronic databases. We in-cluded any RCTs evaluating CIK cellcombination with TACE for the treatment of hepatocellular cancers. The quality of RCTs meeting inclusion criteria was evaluated and data on short-term and long-term curative ef ects, quality of life, liver function and immunologic function were extracted. For quantitative data, we conducted meta-analysis with ReMan 5.1 software and the GRADE System was used to rate the level of evidence and strength of recommendation. For qualitative data, data mainly adopted descriptive methods. Results：The 9 RCTs involving 870 cases meeting the inclusion criteria were included. The meta-analysis showed significant survival benefit on 0.5-year survival rate （RR=1.51, 95%CI, 1.35-1.69, P〈0.00001） in fa-vor of CIK based therapy. This ef ect was consistent at other prospective dates, including 1-year survival rate （RR=2.30, 95%CI, 1.94-2.72, P〈0.00001）, 2-year survival rate （RR=7.03, 95%CI, 3.83-12.91, P〈0.0001）. Meanwhile, the CIK-based group also demonstrated a significantly prolonged time-to-progression （TTP）（SD=1.62, 95%CI, 1.30-1.94, P〈0.0001） and overal survival （OS）（SD=20.6, 95%CI, 20.2-21.18, P〈0.0001）. Moreover, a favored response rate （RR=CR＋PR）（RR=2, 95%CI, 1.65-2.43, P〈0.00001） and the quality of life improvement rate （KPS）（RR=1.76, 95%CI, 1.26-2.45, P=0.0008） were also observed in patients receiving CIK cells and TACE therapy. Furthermore, patients in the CIK group showed lower AFP （SD=-165.23, 95%CI,-178.51--151.94, P〈0.00001）, ALT （SD=-33.14, 95%CI,-40.30--36.37, P〈0.00001）, and

关键词： cytokine-induced kil er (CIK) cel transcatheter arterial chemoembolization (TACE) hepatocellular carcinoma (HCC) meta-analysis GRADE system

Systemic inflammatory response index is a predictor of prognosis in gastric cancer patients: Retrospective cohort and meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 382-395页

作者： Jing-Yao Ren Meng Xu xiang-Dong Niu Shi-Xun Ma Ya-Jun Jiao Da Wang miao Yu Hui Cai School of Clinical Medicine Ningxia Medical UniversityYinchuan 750000Ningxia Hui autonomous regionChina Gansu Provincial Hospital Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina General Surgery Clinical Medical Center Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Medical College of Jiangsu University Jiangsu UniversityZhenjiang 212013Jiangsu ProvinceChina Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND The systemic inflammatory response index(SIRI)has been demonstrated to make a significant difference in assessing the prognosis of patients with different solid ***,research is needed to ascertain the accuracy and reliability of applying the SIRI to patients who undergo robotic radical gastric cancer *** To validate the applicability of the SIRI in assessing the survival of gastric cancer patients and evaluate the clinical contribution of preoperative SIRI levels to predicting long-term tumor outcomes in patients,who received robotic radical gastric cancer *** Initially,an exhaustive retrieval was performed in the PubMed,the Cochrane Library,EMBASE,Web of Science,and Scopus databases to identify relevant ***,a meta-analysis was executed on 6 cohort studies iden-tifying the value of the SIRI in assessing the survival of gastric cancer ***,the clinical data of 161 patients undergoing robotic radical gastric cancer surgery were retrospectively analyzed to evaluate their clinicopathological characteristics and relevant laboratory *** association between preoperative SIRI levels and 5-year overall survival(OS)and disease-free survival(DFS)was *** The findings demonstrated an extensive connection between SIRI values and the outcome of patients with gastric *** SIRI levels were identified as an independent hazard feature for both OS and DFS among those who received robotic surgery for gastric *** levels in gastric cancer patients were observed to be associated with the presence of comorbidities,T-stage,carcinoembryonic antigen levels,the development of early serious postoperative complications,and the rate of lymph node *** SIRI values are correlated with adverse in the gastric cancer population and have the potential to be utilized in predicting long-term oncological survival in patients who undergo robotic radical gastric canc

关键词： Systemic inflammatory response index Prognosis Gastric cancer Complications Meta-analysis