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Chinese Chemical Letters 2006年第7期17卷 925-928页

作者： xiang dong xu Yong Gang HU Ze Yu YANG Institute of Environmental Science ＆ Engineering Huazhong University of Science and Technology Wuhan 430074 Department of Chemistry Huazhong University of Science and Technology Wuhan 430074

A capillary electrophoresis（CE） with on-line inhibited chemiluminescence （CL） detection was firstly used for the simultaneous analysis of benzenediol isomers and phenol. It is based on the quenching effect of benzenediol isomers and phenol on the chemiluminescence reaction of luminol with potassium ferricyanide in sodium hydroxide medium. Under the optimum conditions, the four phenols were baseline separated and detected in less than 10 rain. The detection limits （S/N=3） for hydroquinone, resorcinol, catechol and phenol were 2.9×10^-8 mol/L, 3.7×10^-7 mol/L, 8.4×10^-8 mol/L and 4.4×10^-6 mol/L, respectively. Finally, the presented method has been successfully applied to real sample.

关键词： Capillary electrophoresis chemiluminescence phenol benzenediol isomers wastewater.

De Winter syndrome and ST-segment elevation myocardial infarction can evolve into one another: Report of two cases

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World Journal of Clinical Cases 2019年第20期7卷 3296-3302页

作者： Yang-Yi Lin Yu-Dan Wen Guo-Lin Wu xiang-dong xu Department of Cardiology Jiading District Central Hospital Affiliated Shanghai University of Medical and Health SciencesShanghai 201800China Department of Electrocardiology the Third Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325200Zhejiang ProvinceChina

BACKGROUND The de Winter electrocardiography(ECG)pattern is a sign that implies proximal left anterior descending coronary artery occlusion in patients with chest *** previous view was that the de Winter ECG pattern is *** SUMMARY A 65-year-old man presented with sudden chest pain at rest associated with diaphoresis for 55 *** first ECG showed only T-wave inversion in III and aVF *** ECG was performed at the 100th minute,showing upsloping ST segments depressed with tall and symmetrical T waves in the precordial leads;the J point was raised by 0.1 mV at the aVR *** patient was referred to our catheterization laboratory.A third ECG showed ST segment elevation by 0.2 mV in the I and aVL *** patient underwent emergency coronary angiography,which revealed complete proximal left anterior descending coronary(LAD)*** second patient presented with a 1-h history of sudden-onset,severe,substernal crushing chest *** first ECG showed STsegment elevation(0.1–1.7 mV)in I,aVL,and precordial *** patient was referred to the catheterization *** arrival,his symptoms alleviated,and ECG showed that the ST-segments had significantly fallen *** third ECG showed a typical de Winter *** angiography revealed 99%stenosis of the middle *** The de Winter ECG pattern is transient and dynamic,and it reflects proximal or mid-LAD subtotal occlusion rather than total occlusion.

关键词： De Winter syndrome ST-segment upsloping depression Dynamic Case report

A novel method for Co(Ⅱ) and Cu(Ⅱ) analysis by capillary electrophoresis with chemiluminescence detection

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Chinese Chemical Letters 2007年第9期18卷 1095-1098页

作者： Xiao Ming Guo xiang dong xu Hui Jing Zhang Yong Gang Hu Jie Zhang Institute of Environmental Science&Engineering Huazhong University of Science and TechnologyWuhan 430074China Department of Chemistry Huazhong University of Science and TechnologyWuhan 430074China

Based on the fact that some metal ions can catalyze the chemiluminescence(CL)reaction of luminol with K_3Fe(CN)_6,a novel capillary electrophoresis CL method was developed for the determination of Co(Ⅱ)and Cu(Ⅱ).The separation was carried out with a 10 mmol/L sodium acetate solution containing 0.8 mmol/L luminol and 2.0 mmol/Lα-HIBA(adjusted to pH 4.8 by HAc solution).The post-capillary reagent was 2.0 mmol/L K_3Fe(CN)_6 which was adjusted to pH 13.0 by NaOH *** the optimum conditions,the detection limits(S/N=3)for Co(Ⅱ)and Cu(Ⅱ)were 7.5×10^(-11)mol/L and 7.5×10^(-9)mol/L,with the linear range of 7.5×10^(-9)mol/L to 1.0×10^(-6)mol/L and 7.5×10^(-8)mol/L to 5.0×10^(-5)mol/L, respectively.

关键词： Capillary electrophoresis Chemiluminescence Co(Ⅱ) Cu(Ⅱ)

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数字资本逻辑批判的四重维度

经济学家 2022年第1期 36-44页

作者：王淼向东旭中央财经大学马克思主义学院

数字资本逻辑批判是在马克思资本逻辑批判基础上建立起来的。在新的时代条件下,数字资本逻辑批判可以从前提条件、表现形式、意识形态以及阶级实质四个维度加以理解。在前提条件维度,建立在生产资料私人所有制基础上的数据成为数字资本... 详细信息

数字资本逻辑批判是在马克思资本逻辑批判基础上建立起来的。在新的时代条件下,数字资本逻辑批判可以从前提条件、表现形式、意识形态以及阶级实质四个维度加以理解。在前提条件维度,建立在生产资料私人所有制基础上的数据成为数字资本主义时代"普照的光"和"特殊的以太",是资本家阶级统治和权力支配的前提和基础;在表现形式维度,数字资本逻辑所体现的仍然是一种生产支配人、物支配人、人支配人的社会关系;在意识形态维度,数字资本逻辑借助技术主义、新自由主义、新消费主义等隐藏在数字技术背后,显得更具迷惑性;在阶级实质维度,数字资本逻辑背后仍然是一个阶级对立的剥削世界。从以上几个维度把握当代数字资本主义的新发展、新变化、新问题,对于我们揭示其新的变化发展规律,认清数字资本逻辑的内在本质和特征,从而构建人类命运共同体、实现人的自由而全面发展具有重大理论意义和现实价值。

关键词：数字资本逻辑资本主义私有制数据数字劳动生产关系

Decreased and dysfunctional circulating endothelial progenitor cells in patients with chronic obstructive pulmonary disease

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Chinese Medical Journal 2013年第17期126卷 3222-3227页

作者： GAN Ye CAO Jun CHEN Yan HE Zhi-hui LUO Hong CAI Shan xiang xu-dong ZHOU Rui CHEN Ping YANG Yue Department of Geriatrics Second Xiangya Hospital of Central South University Changsha Hunan 410011 China Departement of Rehabilitation Medicine Second Xiangya Hospital of Central South University Changsha Hunan 410011 China Department of Respiratory Medicine Second Xiangya Hospital of Central South University Changsha Hunan 410011 China Department of Intensive Care Unit Second Xiangya Hospital of Central South University Changsha Hunan 410011 China Department of Emergency Medicine Second Xiangya Hospital of Central South University Changsha Hunan 410011 China Department of Respiratory Medicine Hunan Provincial People's Hospital Changsha 410005 China

Background It has been widely demonstrated that endothelial progenitor cells are involved in several diseases and that they have therapeutic implications. In order to define the altered pulmonary vascular homeostasis in chronic obstructive pulmonary disease, we sought to observe the level and functions of circulating endothelial progenitor calls in patients with chronic obstructive pulmonary disease. Methods The total study population included 20 patients with chronic obstructive pulmonary disease and 20 control subjects. The number of circulating endothelial progenitor cells （CD34＋/CD133＋/IVEGFR-2＋cells） was counted by flow cytometry. Circulating endothelial progenitor cells were also cultured in vitro and characterized by uptake of Dil- acLDL, combining with UEA-I, and expression of von Willebrand factor and endothelial nitric oxide synthase. Adhesion, proliferation, production of nitric oxide, and expression of endothelial nitric oxide synthase and phosphorylated-endothelial nitric oxide synthase were detected to determine functions of circulating endothelial progenitor cells in patients with chronic obstructive pulmonary disease. Results The number of circulating endothelial progenitor cells in the chronic obstructive pulmonary disease group was lower than in the control group：（0.54±0.16）% vs. （1.15±0.57）%, P 〈0.05. About 80% of adherent peripheral blood mononuclear cells cultured in vitro were double labeled with Dil-acLDL and UEA-I. The 92% and 91% of them were positive for von Willebrand factor and endothelial nitric oxide synthase, respectively. Compared with the control, there were significantly fewer adhering endothelial progenitor cells in chronic obstructive pulmonary disease patients： 18.7±4.8/field vs. 45.0±5.9/field, P 〈0.05. The proliferation assay showed that the proliferative capacity of circulating endothelial progenitor cells from chronic obstructive pulmonary disease patients was significantly impaired： 0.135±0.038 vs. 0.224±0.042, P 〈0.05. Fur

关键词： circulating endothelial progenitor cells chronic obstructive pulmonary disease endothelial nitric oxide synthase nitric oxide

Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

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Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi xu Junqiu Jia Rui Mao xiang Cao Yun xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

服务计算中服务质量的多目标优化模型与求解研究

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计算机学报 2015年第10期38卷 1907-1923页

作者：林闯陈莹黄霁崴向旭东清华大学计算机科学与技术系北京100084 北京邮电大学网络与交换技术国家重点实验室北京100876 北京科技大学计算机与通信工程学院北京100083

随着信息技术的不断发展和进步,传统的面向组件和系统的架构模式逐渐演变成面向服务的设计模式.服务计算作为一种新兴的计算模式应运而生并广泛应用于各个领域.随着用户和服务供应商需求日趋多样化,如何对服务系统进行最佳配置和管理,... 详细信息

随着信息技术的不断发展和进步,传统的面向组件和系统的架构模式逐渐演变成面向服务的设计模式.服务计算作为一种新兴的计算模式应运而生并广泛应用于各个领域.随着用户和服务供应商需求日趋多样化,如何对服务系统进行最佳配置和管理,提供最优的服务质量,越来越受到研究者的关注,服务计算中服务质量的多目标优化成为研究热点.由于不同目标之间可能存在相互制约和折中的关系,多目标优化问题面临着难题和挑战.文中从服务计算中广泛关注的多维度指标体系出发,结合具体的研究问题,总结了5种典型的多目标优化模型,并从适用性、求解难度等多个角度对它们进行了分析和比较,同时讨论了模型的相互关系.对应优化模型,介绍和分析了常用的多目标优化求解方法.最后,对全文进行了总结,并对下一步的研究方向进行了展望.

关键词：服务计算服务质量多目标指标体系多目标优化

牙龈生物型对上颌单颗后牙种植体周围骨组织、软组织健康及龈乳头美学效果的影响

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上海口腔医学 2024年第3期33卷 290-294页

作者：杨成栋向旭东淄博市第一医院口腔科山东淄博255200

目的:探讨牙龈生物型对上颌单颗后牙种植体周围骨组织、软组织健康及龈乳头美学效果的影响。方法:选择2019年5月—2022年9月收治的78例行上颌单颗后牙种植术患者,共植入78颗种植体。种植修复后1个月,根据牙周探诊结果分为薄龈生物型组(n... 详细信息

目的:探讨牙龈生物型对上颌单颗后牙种植体周围骨组织、软组织健康及龈乳头美学效果的影响。方法:选择2019年5月—2022年9月收治的78例行上颌单颗后牙种植术患者,共植入78颗种植体。种植修复后1个月,根据牙周探诊结果分为薄龈生物型组(n=32)与厚龈生物型组(n=46),比较种植修复后6个月的颊侧角化龈宽度(keratinized mucosa width,KMW)、骨吸收量(implant bone loss,IBL)、改良菌斑指数(modified plaque index,mPLI)、种植体改良出血指数(modified bleeding index,mBLI)、种植体探诊深度(probing pocket depth,PPD)、龈乳头指数(papilla index Score,PIS)、食物嵌塞、牙龈边缘颜色满意度指数(gingival margin color satisfaction index,GMCS)。通过Pearson分析评估牙龈生物型及角化龈宽度与种植体周围骨组织、软组织健康及龈乳头美学效果的相关性,比较不同牙龈生物型及角化龈宽度患者发生黏膜退缩的情况。采用SPSS 27.0软件包对数据进行统计学分析。结果:厚龈组KMW高于薄龈组,差异有统计学意义(P2 mm时,薄龈组和厚龈组相比有统计学差异(P2 mm时,厚龈组差异有统计学意义(P<0.05)。结论:牙龈生物型对上颌单颗后牙种植体周围骨组织、软组织健康及龈乳头美学效果存在影响,对于预测种植体长期成功及美学效果具有指导意义。

关键词：牙龈生物型角化龈宽度上颌单颗后牙种植体软组织健康美学效果

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一种基于混沌的代换-置换结构图像加密算法

计算机科学 2014年第9期41卷 158-164页

作者：蔡俊陈昕向旭东北京信息科技大学计算机学院北京100101 北京科技大学计算机与通信工程学院北京100083

近年来,随着多媒体技术的发展,互联网上数字图像相关内容和应用的比例越来越高,其安全性也日益受到人们的关注。图像的安全性,一般通过加密方法来保证。图像加密算法中,基于置乱-扩散结构的加密算法因其充分考虑图像数据二维分布的特点... 详细信息

近年来,随着多媒体技术的发展,互联网上数字图像相关内容和应用的比例越来越高,其安全性也日益受到人们的关注。图像的安全性,一般通过加密方法来保证。图像加密算法中,基于置乱-扩散结构的加密算法因其充分考虑图像数据二维分布的特点,特别适合图像数据的加密。然而,该加密算法存在安全性不高、扩散效率低,以及密钥扩展计算复杂度高等问题。通过引入分组密码学中的代换-置换(SP,Substitution-Permutation)结构,提出了一种基于混沌的SP结构图像加密算法SPCME,该算法采取3种策略:(1)通过混沌映射进行置换和扩散,采用AES算法的S盒进行字节代换,以增强算法安全性;(2)使用双向的置乱-扩散策略,加快扩散速度;(3)运用简单的异或和移位操作,提高密钥扩展效率。为评价该算法的性能,文中做了密钥空间分析、密钥敏感性分析、统计直方图分析、相邻像素相关性分析、信息熵分析、差分攻击分析等大量的性能分析实验。实验结果表明,该算法仅通过3轮迭代就可达到与以前提出的图像加密算法相同的安全级别,加密效率明显提高。

关键词： SP结构图像加密混沌三维Arnold映射 Logistic映射

DAS:GSPN成员载波动态自适应调度策略

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计算机科学 2016年第11期43卷 111-116页

作者：贾玉栋陈昕向旭东北京信息科技大学计算机学院北京100101 北京科技大学计算机与通信工程学院北京100083

随着移动业务需求的多样化,有限的无线频谱资源已无法满足用户对高质量、高效率和高带宽的数据业务的需求。在现有的低频载波环境下,引入高频载波可以有效扩大系统容量。在同一小区部署多个成员载波的过程中,成员载波调度策略是其中的... 详细信息

随着移动业务需求的多样化,有限的无线频谱资源已无法满足用户对高质量、高效率和高带宽的数据业务的需求。在现有的低频载波环境下,引入高频载波可以有效扩大系统容量。在同一小区部署多个成员载波的过程中,成员载波调度策略是其中的关键问题之一,直接影响LTE用户的服务质量(Qulity of Service,QoS)和无线资源的利用率。针对蜂窝网络中成员载波的调度策略问题,采用广义随机Petri网(Generalized Stochastic Petri Nets,GSPN)方法建立了多成员载波系统模型,同时在分析用户业务类型和成员载波特性的基础上,提出了一种动态自适应调度策略(Dynamic Adaptive Scheduling,DAS)。通过TimeNets仿真工具,对系统中成员载波选择、用户排队机制和资源块(Resource Block,RB)分配等要素构建仿真环境。仿真实验结果表明:一方面,动态自适应调度策略(Dynamic Adaptive Scheduling,DAS)的掉线率低于基于服务类型的调度策略(Based-Service Scheduling,BSS)和最短队列优先调度策略(Shortest Queue priority Scheduling,SQP);另一方面,在相同的到达率的前提下,在到达率较低时,其吞吐量逼近于基于服务类型的调度策略BSS;在到达率较高时,逼近于最短队列优先调度策略SQP。

关键词：成员载波 LTE 广义随机Petri 掉线率吞吐量