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Experimental Study on Mixed-Mode(Ⅰ–Ⅱ)Fracture Toughness of Freshwater Ice

Acta Mechanica Solida Sinica 2024年第2期37卷 252-264页

作者： Yaozhong Xu mao Zhou xian Yi Wen hua Jiuzhou huang Wenyu Zhang Shiming Dong Key Laboratory of Deep Underground Science and Engineering Ministry of EducationCollege of Architecture and EnvironmentSichuan UniversityChengdu610065China Failure Mechanics and Engineering Disaster Prevention Key Laboratory of Sichuan Province Sichuan UniversityChengdu610065China China Aerodynamics Research and Development Center/Low Speed Aerodynamics Research Institute Mianyang621000China College of Mechanical and Electrical Engineering Xichang UniversityXichang615000China

In recent years,the issue of aircraft icing has gained widespread *** breaking and detachment of dynamic ice can pose a threat to flight ***,the shedding and fracture mechanisms of dynamic ice are unclear and cannot meet the engineering needs of ice-shedding hazard ***,studying the fracture toughness of ice bodies has extremely important practical *** address this issue,this article uses a centrally cracked Brazilian disk(CCBD)specimen to measure the pure modeⅠtoughness and pure modeⅡfracture toughness of freshwater ice at different loading *** mixed-mode(Ⅰ–Ⅱ)fracture characteristics of ice are discussed,and the experimental results are compared and analyzed with the theoretical values of the generalized maximum tangential stress(GMTS)criterion considering the influence of *** results indicated that as the loading rate increases,the pure modeⅠtoughness and pure modeⅡfracture toughness of freshwater ice decrease,and the fracture toughness of freshwater ice is more sensitive to the loading rate.Ⅰn terms of fracture criteria,the theoretical value of the ratio of pure modeⅡfracture toughness to pure modeⅠfracture toughness based on the GMTS criterion is in good agreement with the experimental value,while the theoretical value based on the maximum tangential stress(MTS)criterion deviates significantly from the experimental value,indicating that the GMTS criterion considering the influence of T-stress can better predict the experimental results.

关键词： Freshwater ice Fracture criteria Centrally cracked Brazilian disk(CCBD) Mixed-mode(Ⅰ-Ⅱ) Loading rate

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Carvedilol Versus Other Nonselective Beta Blockers for Variceal Bleeding Prophylaxis and Death: A Network Meta-analysis

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Journal of Clinical and Translational Hepatology 2023年第5期11卷 1143-1149页

作者： Ka-Shing Cheung Chiu-Hang Mok Lok-Ka Lam xian-hua mao Lung-Yi Mak Wai-Kay Seto Man-Fung Yuen Department of Medicine School of Clinical MedicineThe University of Hong KongQueen Mary HospitalHong KongChina Department of Medicine The University of Hong Kong-Shenzhen HospitalShenzhenGuangdongChina School of Clinical Medicine The University of Hong KongHong KongChina State Key Laboratory of Liver Research The University of Hong KongHong KongChina

Background and Aims:We aimed to perform a network meta-analysis(NWM)to examine comparative effectiveness of non-selective beta blockers(NSBBs)on prophylaxis of gastroesophageal variceal bleeding(GVB)and mortality ***:MEDLINE(OVID)and EMBASE databases were searched for eligible randomized clinical trials(RCTs)from inception to July 3,*** of interest included primary/secondary prophylaxis of GVB,failure to achieve hepatic venous pressure gradient(HVPG)decremental response,liver-related and all-cause mortality.A Bayesian NWM was performed to derive relative risk(RR)with 95%credible intervals(CrIs).The ranking probability of each NSBB was assessed by surface under cumulative ranking curve(SUCRA).Results:Thirty-three RCTs including 3,188 cirrhosis patients with gastroesophageal varices were *** with placebo,nadolol ranked first for reducing variceal bleeding[RR:0.25,(95%CrI:0.11–0.51);SUCRA:0.898],followed by carvedilol[RR:0.33,(95%CrI:0.11–0.88);SUCRA:0.692]and propranolol[RR:0.52,(95%CrI:0.37–0.75);SUCRA:0.405].Carvedilol was more effective than propranolol in achieving HVPG decremental response[RR:0.43,(95%CrI:0.26–0.69)].Carvedilol ranked first for reducing all-cause mortality[RR:0.32,(95%CrI:0.17–0.57);SUCRA:0.963],followed by nadolol[RR:0.48,(95%CI:0.29–0.77);SUCRA:0.688],and propranolol[RR:0.77,(95%CI:0.58–1.02);SUCRA:0.337].Similar findings were observed for liver-related *** ranked the *** RR of adverse events was 4.38,(95%CrI:0.33–161.4);SUCRA:0.530,followed by propranolol[RR:7.54,(95%CrI:1.90–47.89);SUCRA:0.360],and nadolol[RR:18.24,(95%CrI:91.51–390.90);SUCRA:0.158].Conclusions:Carvedilol is the preferred NSBB with better survival benefit and lower occurrence of adverse events among patients with gastroesophageal varices.

关键词： NSBB Carvedilol Nadolol Propranolol Varices Cirrhosis CPSH

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Hyperspectral image super resolution using deep internal and self-supervised learning

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CAAI Transactions on Intelligence Technology 2024年第1期9卷 128-141页

作者： Zhe Liu xian-hua Han Graduate School of Science and Technology for Innovation Yamaguchi UniversityYamaguchiJapan Graduate School of Artificial Intelligence and Science Rikkyo UniversityTokyoJapan

By automatically learning the priors embedded in images with powerful modelling ca-pabilities,deep learning-based algorithms have recently made considerable progress in reconstructing the high-resolution hyperspectral(HR-HS)*** previously collected large-amount of external data,these methods are intuitively realised under the full supervision of the ground-truth ***,the database construction in merging the low-resolution(LR)HS(LR-HS)and HR multispectral(MS)or RGB image research paradigm,commonly named as HSI SR,requires collecting corresponding training triplets:HR-MS(RGB),LR-HS and HR-HS image simultaneously,and often faces dif-ficulties in *** learned models with the training datasets collected simultaneously under controlled conditions may significantly degrade the HSI super-resolved perfor-mance to the real images captured under diverse *** handle the above-mentioned limitations,the authors propose to leverage the deep internal and self-supervised learning to solve the HSI SR *** authors advocate that it is possible to train a specific CNN model at test time,called as deep internal learning(DIL),by on-line preparing the training triplet samples from the observed LR-HS/HR-MS(or RGB)images and the down-sampled LR-HS ***,the number of the training triplets extracted solely from the transformed data of the observation itself is extremely few particularly for the HSI SR tasks with large spatial upscale factors,which would result in limited reconstruction *** solve this problem,the authors further exploit deep self-supervised learning(DSL)by considering the observations as the unlabelled training ***,the degradation modules inside the network were elaborated to realise the spatial and spectral down-sampling procedures for transforming the generated HR-HS estimation to the high-resolution RGB/LR-HS approximation,and then the reconstruction errors of the observations were formulated for mea

关键词： computer vision deep learning deep neural networks hyperspectral image enhancement

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Cretaceous magmatic arc in Hainan and the peri-South China Sea asevidenced by geochemical fingerprinting of granitoids in the region

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Geoscience Frontiers 2024年第5期15卷 355-371页

作者： Xiao-Yan Jiang Yildirim Dilek xian-hua Li State Key Laboratory of Ore Deposit Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Department of Geology and Environmental Earth Science Miami UniversityOxfordOH 45056USA

Mesozoic magmatic rocks occur widely in the South China Block and are generally interpreted as the manifestations of the subduction of the Paleo-Pacific oceanic lithosphere beneath *** magmatism in southeast(SE)China continued from the Late Permian through the Late Cretaceous with an inferred lull between 125 Ma and 115 Ma that is known in the literature as the Cretaceous"magmatic quiescence".We report in-situ zircon U-Pb ages,Hf-O and whole-rock Sr-Nd isotopes,and whole-rock geochemistry of Cretaceous granitoids on Hainan Island and discuss their magmatic evolution within the framework of the Late Mesozoic geodynamics of SE *** recognize two main stages of the emplacement of Cretaceous granitoids on Hainan,first around 120 Ma and then around 100-95 Ma,displaying high-K calc-alkaline,I-type geochemical *** in both age groups are enriched in LILE and LREE,but depleted in Nb,Ta,Ba,Sr,and *** 120 Ma granites have zircon ε_(Hf)(t)values of-2.6 to 2.3 corresponding to Hf crustal model ages,ranging from 0.79 Ga to 1.03 Ga,and δ^(18)O values ranging from 6.9‰to 7.7‰.Zircons from 100-95 Ma granites have ε_(Hf)(t)values of-4.2 to 1.1 corresponding to Hf crustal model ages of 1.08 Ga to 1.42 Ga,and δ^(18)O values ranging from 6.7‰to 8.4‰.Increasing ε_(Hf)(t)values of the Cretaceous Hainan granites with younger crystallization ages indicate addition of more juvenile components and reworking of crustal material into their melt *** ε_(Nd)(t)values of the 120 Ma and 100-95 Ma granitoids range between-4.1 to-0.4 and-7.7 to-4.0,*** calculated two-stage model age of the 100-95 Ma granitoids clusters between 1.25 Ga and 1.53 *** isotopic data suggest that magmas of the Cretaceous granitoids were produced by partial melting of Mesoproterozoic metabasaltic rocks,which make up much of the crystalline basement of the southern Cathaysia *** geochemical and isotopic characteristics of the Cretaceous granitoids on H

关键词： I-type granites Cretaceous Hainan Island Southeast China Magmatic arc peri-South China Sea region

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Quasi-shadowing for Z^(d)-actions

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1563-1580页

作者： Juan PAN xian Kun REN Yun hua ZHOU School of Mathematics and Statistics Chongqing Technology and Business UniversityChongqing 400067P.R.China College of Mathematics and Statistics Chongqing UniversityChongqing 401331P.R.China

A diffeomorphism is non-uniformly partially hyperbolic if it preserves an ergodic measure with at least one zero Lyapunov *** prove that a C^(1)-smooth Z^(d)-action has the quasishadowing property if one of the genera... 详细信息

关键词： Quasi-shadowing Z^(d)-action non-uniformly partially hyperbolic ergodic measure

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Preface to special issue on celebrating the 100th anniversary of Xinjiang University

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Nano Research 2024年第1期17卷 1-4页

作者： Dianzeng Jia Ruimao hua xian-He Bu Yuliang Li State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources College of ChemistryXinjiang UniversityUrumqi 830017China Department of Chemistry Tsinghua UniversityBeijing 100084China School of Materials Science and Engineering Nankai UniversityTianjin 300350China CAS Key Laboratory of Organic Solids Institute of ChemistryChinese Academy of SciencesBeijing 100190China

Xinjiang University originated from Xinjiang College of Russian Language,Political Science and Law in *** 1935 and 1960,the college was re-organized and re-named as Xinjiang College and Xinjiang University,*** 1978,Xinjiang University was appointed by the State Council as the only national key university in *** 1997,it was designated as one of the first batch of key construction universities in the“211 Project”of *** 2000,Xinjiang University was rebuilt through merging with Xinjiang Institute of Technology.

关键词： Xinjiang anniversary originated

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Clinical characteristics and treatment of splenic infarction in children with systemic lupus erythematosus

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World Journal of Pediatrics 2024年第5期20卷 525-531页

作者： Yan Li Yu-Rong Piao Tong-Xin Han hua-Wei mao Department of Immunology Ministry of Education Key Laboratory of Major Diseases in ChildrenBeijing Key Laboratory for Genetics of Birth DefectsNational Center for Children’s HealthBeijing Children’s HospitalCapital Medical UniversityNo.56 Nan Li Shi LuBeijing100045China

Splenic infarction(SI)is a rare clinical phenomenon that occurs when the blood supply to the spleen is interrupted,resulting in tissue ischemia and necrosis[1].There are many causes of SI;in adult patients,cardioembolism,hematological malignancy,and infectious disease are the most common[2].Rheumatic diseases,especially systemic lupus erythematosus(SLE)and granulomatosis with polyangitis,can also lead to SI[3];however,only a few cases have been *** are currently no statistically meaningful data on the etiology of SI in *** most patients with SI can recover after conservative treatment,a small number of patients develop complications,such as splenic abscess,splenic rupture,splenic hemorrhage,and hemoperitoneum,and may even undergo splenectomy in severe cases.

关键词： erythematosus lupus treatment

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Molecular mechanism for the unusual enhancement of the second-step chemiluminescence production from the carcinogenic tetrabromohydroquinone and H2O_(2)

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Journal of Environmental Sciences 2024年第7期141卷 330-342页

作者： Zi-Han Wang Chun-hua huang Zhi-Sheng Liu Li mao Ben-Zhan Zhu State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Environment and Resources University of Chinese Academy of SciencesBeijing 100049China

We have found recently that two-step intrinsic hydroxyl radical(·OH)-dependent chemiluminescence(CL)could be produced by carcinogenic tetrahaloquinone and H_(2)O_(2).However,the first-step CL was too fast to clearly detect the stepwise generation of·OH and CL,and to distinguish the exact dividing point between the first-step and second-step *** we found that,extremely clear two-step intrinsic CL could be produced by the relative slow reaction of tetrabromohydroquinone(TBHQ)with H_(2)O_(2),which was directly dependent on the two-step·OH ***,the second-step,but not the first-step CL production of TBHQ/H_(2)O_(2)(CRET donor)was markedly enhanced by fluorescein(a typical xanthene dye,CRET acceptor)through a unique chemiluminescence resonance energy transfer(CRET)*** novel CRET system of TBHQ/H_(2)O_(2)/fluorescein was successfully applied for the sensitive detection of TBHQ with the detection limit as low as 2.5μmol/*** findings will help to develop more sensitive and highly efficient CL or CRET systems and specific CL sensor to detect the carcinogenic haloquinones,which may have broad environmental applications.

关键词： Two-step chemiluminescence Bromohydroquinone Hydrogen peroxide Hydroxyl radical CRET

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λ/20-Thick cavity for mimicking electromagnetically induced transparency at telecommunication wavelengths

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Advanced Photonics 2024年第3期6卷 42-50页

作者： hua Lu Shouhao Shi Dikun Li Shuwen Bo Jianxu Zhao Dong mao Jianlin Zhao Northwestern Polytechnical University School of Physical Science and TechnologyMOE Key Laboratory of Material Physics and Chemistry under Extraordinary ConditionsKey Laboratory of Light-Field Manipulation and Information AcquisitionMinistry of Industry and Information TechnologyShaanxi Key Laboratory of Optical Information TechnologyXi’anChina

Optical cavities play crucial roles in enhanced light-matter interaction,light control,and optical communications,but their dimensions are limited by the material property and operating *** planar cavities are urgently in demand for large-area and integrated optical ***,extremely reducing the planar cavity dimension is a critical challenge,especially at telecommunication ***,we demonstrate a type of ultrathin cavities based on large-area grown Bi_(2)Te_(3)topological insulator(TI)nanofilms,which present distinct optical resonance in the near-infrared *** result shows that the Bi_(2)Te_(3)TI material presents ultrahigh refractive indices of>6 at telecommunication *** cavity thickness can approach 1/20 of the resonance wavelength,superior to those of planar cavities based on conventional Si and Ge high refractive index ***,we observed an analog of the electromagnetically induced transparency(EIT)effect at telecommunication wavelengths by depositing the cavity on a photonic *** EIT-like behavior is derived from the destructive interference coupling between the nanocavity resonance and Tamm *** spectral response depends on the nanocavity thickness,whose adjustment enables the generation of obvious Fano *** experiments agree well with the *** work will open a new door for ultrathin cavities and applications of TI materials in light control and devices.

关键词： topological insulator optical nanocavity photonic crystal electromagnetically induced transparency-like effect

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Cytoplasmic FKBPs are involved in molting and metamorphosis through regulating the nuclear localization of EcR

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Insect Science 2024年第3期31卷 759-772页

作者： xian Zhang Qiao-Ran Wang Qian Wu Jun Gu Li-hua huang Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology School of Life SciencesSouth China Normal UniversityGuangzhouChina Guangmeiyuan R&D Center Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied TechnologySouth China Normal UniversityMeizhouChina

Molting and metamorphosis are important physiological processes in insects that are tightly controlled by ecdysone receptor(EcR)through the 20-hydroxyecdysone(20E)signaling *** is a steroid nuclear receptor(SR).Several FK506-binding proteins(FKBPs)have been identified from the mammal SR complex,and are thought to be involved in the subcellular trafficking of ***,their roles in insects are poorly *** explore whether FKBPs are involved in insect molting or metamorphosis,we injected an FKBP inhibitor(FK506)into a lepidopteran insect,Spodoptera litura,and found that molting was inhibited in 61.11%of the larvae,and that the time for larvae to pupate was significantly extended.A total of 10 FKBP genes were identified from the genome of *** and were clustered into 2 distinct groups,according to their subcellular localization,with FKBP13 and FKBP14 belonging to the endoplasmic reticulum(ER)group and with the other members belonging to the cytoplasmic(Cy)*** the CyFKBPs were significantly upregulated in the prepupal or pupal stages,with the opposite being observed for the ER group ***506 completely blocked the transfer of EcR to the nucleus under 20E induction,and significantly downregulated the transcriptional expression of many 20E signaling genes.A similar phenomenon was observed after RNA interference of2 CyFKBPs(FKBP45 and FKBP12b),but not for *** together,our data indicate that the cytoplasmic FKBPs,especially FKBP45 and FKBP12b,mediate the nuclear localization of EcR,thereby regulating the 20E signaling and ultimately affecting molting and metamorphosis in insects.

关键词： EcR FKBP metamorphosis molting RNAi subcellular localization

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