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Anti-cyclic citrullinated peptide antibody predicts the development of rheumatoid arthritis in patients with undifferentiated arthritis

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Chinese medical Journal 2019年第24期132卷 2899-2904页

作者： chun Li Yan zhang Hui Song Jie Gao Dong-Bao Zhao Qi Zhu Dong-Yi He Li Wang xiang-Pei Li Xu-Dong Liu Wei-Guo xiao xin-Yu Wu Hua-xiang Wu Wei Tu Shao-xian Hu xin Wang Zhi-Jun Li Zhi-min Lu Zhan-Yun Da Bo Liang xiao-min Liu Jin-Wei Zhao Ling Li Feng Han Wu-fang Qi Wei Wei Xu Ma Zhen-bin Li Gui-min Zheng Feng-xiao zhang Yi Li You-Lian Wang guang-Hui Ling Jin-Wei Chen xiao-Qiang Hou jing zhang Qing-Ping Chen Chang-Lian Liu Yan zhang Jia-Shun Zeng Qing-Hua zou Yong-Fei fang Yin Su Zhan-Guo Li department of Rheumatology and Immunology Peking University People's HospitalBeijing 100044China department of Rheumatology and Immunology Beijing Jishuitan HospitalBeijing 100035China department of Rheumatology and Immunology Changhai HospitalShanghai 200433China department of Rheumatology Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western MedicineShanghai 200052China department of Rheumatology and Immunology Anhui Provincial HospitalHefeiAnhui 230001China department of Rheumatology and Immunology The First Hospital of China Medical UniversityShenyangLiaoning 110001China department of Rheumatology The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiang 310009China department of Rheumatology and Immunology Tongji HospitalWuhanHubei 430030China department of Rheumatology The First Affiliated Hospital of Bengbu Medical CollegeBengbuAnhui 233004China department of Rheumatology and Immunology Affiliated Hospital of Nantong UniversityNantongJiangsu 226001China department of Rheumatology and Immunology The Hospital of Shunyi District BeijingBeijing 101300China department of Infection and Immunology Tianjin Union Medical CenterTianjin 300121China department of Rheumatology and Immunology Tianjin First Central HospitalTianjin 300192China department of Rheumatology and Immunology Tianjin Medical University General HospitalTianjin 300052China department of Rheumatology and Immunology Peace HospitalShijiazhuangHebei 050000China department of Rheumatology and Immunology Hebei General HospitalShijiazhuangHebei 050051China department of Rheumatology Jiangxi Provincial People's HospitalNanchangJiangxi 330006China Division of Rheumatology and Immunology The Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China department of Rheumatology and Immunology The First College of Clinical Medical Science of China Three Gorges University&Yichang Central People's HospitalYichangHubei 443003China department of Rheu

Background:Clinical outcomes of undifferentiated arthritis(UA)are diverse,and only 40%of patients with UA develop rheumatoid arthritis(RA)after 3 *** predictive markers at disease onset for further intervention is ***,our objective was to analyze the clinical outcomes of UA and ascertain the predictors for RA ***:We performed a prospective,multi-center study from January 2013 to October 2016 among Chinese patients diagnosed with UA in 22 tertiary-care *** and serological parameters were obtained at ***-up was undertaken in all patients every 12 weeks for 2 *** factors of disease progression were identified using multivariate Cox proportional hazards ***:A total of 234 patients were recruited in this study,and 17(7.3%)patients failed to follow up during the *** the 217 patients who completed the study,83(38.2%)patients went into *** patients who developed RA had a higher rheumatoid factor(RF)-positivity(42.9%vs.16.8%,χ^2=8.228,P=0.008),anti-cyclic citrullinated peptide(CCP)antibodypositivity(66.7%vs.10.7%,χ^2=43.897,P38.1%vs.4.1%,χ^2=32.131,P3–55.938;P<0.001).Conclusion:As an independent predictor of RA,anti-CCP antibody should be tested at disease onset in all patients with UA.

关键词： Anti-cyclic citrullinated peptide antibody Arthritis,Rheumatoid Rheumatoid factor Undifferentiated arthritis

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-xin Liu Yue Huang guang-Cheng xiao Qing-Cui Bu Jin-Lu Qu Shu zhang Shuang-Nan zhang Shu-Mei Jia fang-Jun Lu xiang Ma Lian Tao Wei zhang Li Chen Li-ming Song Ti-Pei Li Yu-peng Xu Xue-Lei Cao Yong Chen Cong-Zhan Liu Ce Cai Zhi Chang Gang Chen Tian-xiang Chen Yi-Bao Chen Yu-peng Chen Wei Cui Wei-Wei Cui jing-Kang Deng Yong-Wei Dong Yuan-Yuan Du min-Xue Fu guan-Hua Gao He Gao min Gao ming-Yu Ge Yu-Dong Gu Ju guan Cheng-Cheng Guo Da-Wei Han Jia Huo Lu-Hua Jiang Wei-chun Jiang jing Jin Yong-Jie Jin Ling-Da Kong bing Li Cheng-Kui Li Gang Li Mao-Shun Li Wei Li xian Li xiao-Bo Li Xu-fang Li Yang-Guo Li Zheng-Wei Li xiao-Hua Liang jing-Yuan Liao Bai-Sheng Liu Guo-Qing Liu Hong-Wei Liu xiao-jing Liu Yi-Nong Liu Bo Lu Xue-Feng Lu Qi Luo Tao Luo bin meng Yi Nang Jian-Yin Nie Ge Ou Na Sai Ren-Cheng Shang xin-Ying Song Liang Sun Ying Tan You-Li Tuo Chen Wang Guo-Feng Wang Juan Wang Ling-Jun Wang Weng-Shuai Wang Yu-Sa Wang xiang-Yang Wen Bai-Yang Wu Bo-bing Wu Mei Wu Shuo xiao Shao-Lin Xiong He Xu Jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-Jung Yang Qi-bin Yi Qian-Qing Yin Yuan You Ai-Mei zhang Cheng-Mo zhang Fan zhang Hong-Mei zhang Juan zhang Tong zhang Wan-Chang zhang Wen-Zhao zhang Yi zhang Yi-Fei zhang Yong-Jie zhang Yuan-Hang zhang Yue zhang Zhao zhang Zhi zhang Zi-Liang zhang Hai-Sheng Zhao xiao-Fan Zhao shi-Jie Zheng Yao-guang Zheng Deng-Ke Zhou Jian-Feng Zhou Yu-Xuan Zhu Ren-Lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China university of Chinese Academy of sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany department of Astronomy Beijing Normal UniversityBeijing 100088China department of Astronomy Tsinghua UniversityBeijing 100084China department of Physics Tsinghua UniversityBeijing 100084China department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China college of Physics sciences&technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

Consensus statement on layout and delivery of automatic external defibrillator in china

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Journal of Hainan medical university 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen Yan-Fen Chai xiao-Hui Chen Yu-Guo Chen Shao-Wen Cheng Wen-Wei Cheng Bang-Han Ding Yang Deng Jie Fu Bang-Jiang fang Mai-Ying Fan Li Gui Ping Gong Wei Guo Shu-bin Guo Liang Huang Ji-Yuan Han Zhong Ji xian-Fei Ji xin-Cai Ji Hong-Xu Jin xin-Jun Jiang Wang-xiang Jiang Jia-Liang Liu xiao-Ran Liu Zhi Liu Chuan-Zhu Lv Feng Lu Tan-shi Li xin Li Yong Li Shang-Lun Li Shuang-ming Li xiao-Gang Li Bao-Jun Li Pei-Wu Li chun-Sheng Li Zhi-Jun Li Chang-Luo Li xiang-min Li Yin-Ping Li Zong-Jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian Luo xiao-xing Liao Jian-Bo Lei Tao Ma Yu Ma Yue-Feng Ma Qing-Bian Ma Lin-Hao Ma Jun-Qi Ma shi-Nan Nie Jie-Miao Ou-Yang peng peng Qiao Pei Shu-ming Pan Guo-Zhong Qing Li-Jie Qin Wu-Ying Qiao Fei Shao Wei Song xing-Yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian Ying-Ping Tian Jian-guang Tian Chao-Yang Tong Zi-Ren Tang meng-Xiong Tang Guo-Ping Wu Zhi Wan Tao Wang xin Wang peng Wang Zhong Wang Tong Wang Ri-xing Wang Yi-xin Wang xiao-Dan Wang Ling Wu Wei Wei Hua xiang Feng Xu Jun Xu Jie Xu Miao-Rong Xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi Li-Shan Yang shi-Jiao Yan Jin-Jian Yao Shou-chun Yan Xue-Zhong Yu xian-Zhi Ye xian-Liang Yan Fu-bing Zhou Rong-bin Zhou ming Zhou Qiang Zhou Jin Zhou Ping Zhou Chang-Ju Zhu Hua-Dong Zhu Ji-Hong Zhu Hong zhang Mao zhang Hua zhang Na zhang Guo-Qiang zhang Guo-Xiu zhang Jin-Song zhang Wen-Wu zhang Wen-Zhong zhang Jian-Feng zhang Yi-min Zhu Jun Zeng Yuan Zheng Zhi-Jie Zheng Shen Zhao Yan Zhao min Zhao bin Zhao xiao-Dong Zhao xiao-jing Zhao Hong-Ke Zeng Sheng-Qiang zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma college Hainan Medical UniversityHaikouHainanChina department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan medical university

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in china[2].

关键词： cardiac death respiratory

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2005年中国城市CO2排放数据集

中国人口·资源与环境 2018年第4期28卷 1-7页

作者：蔡博峰刘晓曼陆军王金南刘红光陈洋陈占明丛建辉崔志鹏代春艳董会娟方恺冯彤郭杰李芬孟凡鑫唐伟王庚哲谢运生张建军阿依吐尔逊·沙木西布买日也木·买买提蔡伟光曾胜常盼陈前利陈振国单钰理丁冠乔独威范敏冯相昭干晓宇高壮飞谷雨何凌昊何姚胡鸣明黄丽珍黄桥贾小平菊春燕蓝菁李爽李松李耀光李照令刘合林刘婧文刘庆燕刘竹逯飞马贤磊欧金沛潘栋沈杨税月孙露谭效时唐敏唐袆祺王柯王思亓王香爱王晓培吴家杰吴雪萍肖连香邢文婷徐丽笑叶瑞克袁子坤张飞云张袆张明张琦峰张曦文张宇赵晶赵胜男郑思伟周来友朱天琦曹丽斌冯乐李栋李一静龙瀛孙瑞红环境保护部环境规划院北京100012 中国科学院大气物理研究所北京100029 南京农业大学公共管理学院江苏南京210095 上海财经大学城市与区域科学学院上海200433 中国人民大学经济学院北京100872 山西大学经济与管理学院山西太原030006 E20环境平台咨询部北京100195 重庆工商大学长江上游经济研究中心重庆400067 上海交通大学环境科学与工程学院上海200240 浙江大学公共管理学院浙江杭州310058 天津大学管理与经济学部天津300072 南京农业大学土地管理学院江苏南京210095 深圳市建筑科学研究院股份有限公司北京研创中心广东深圳518049 华南理工大学环境与能源学院广东广州510006 杭州市环境保护科学研究院环境政策研究中心浙江杭州310014 埃因霍芬理工大学建筑学院荷兰埃因霍芬5616SC 江西省科学院能源研究所江西南昌330000 中国地质大学(北京)土地科学技术学院北京100083 新疆农业大学管理学院新疆乌鲁木齐830052 重庆大学建设管理与房地产学院重庆400044 重庆工商大学财政金融学院重庆400067 东安格利亚大学国际发展学院英国诺维奇NR47TJ 环境保护部环境发展中心北京100029 环境保护部环境与经济政策研究中心北京100029 四川大学建筑与环境学院四川成都610065 浙江工业大学政治与公共管理学院浙江杭州310023 美国绿色建筑委员会城市与社区部北京100085 挪威科技大学工程学院挪威约尔维克2815 北京师范大学统计学院北京100875 青岛科技大学环境学院山东青岛266000 北京大学遥感与地理信息系统研究所北京100871 北京师范大学环境学院北京100875 筑波大学日本筑波305-0005 华中科技大学建筑与城市规划学院湖北武汉430074 美国东北大学工学院美国波士顿02115 河北省环境科学研究院规划所河北石家庄050037 中山大学地理科学与规划学院广东广州北京林业大学环境科学与工程学院北京宁波职业技术学院商贸外语学院浙江宁波重庆工商大学土地管理学院重庆日本国立环境研究所社会环境系统研究中心日本筑波中国船舶重工集团公司第七一四研究所北京重庆工商大学管理学院重庆渭南师范学院化学与材料学院陕西渭南福州大学经济与管理学院福建福州扬州大学环境科学与工程学院江苏扬州中国矿业大学管理学院江苏徐州北京大学城市与环境学院北京内蒙古大学公共管理学院内蒙古呼和浩特江苏大学财经学院江苏镇江赤峰学院资源与环境科学学院内蒙古赤峰新余学院经济管理学院江西新余北京市环境保护科学研究院生态与城市环境研究所北京北京清华同衡规划设计研究院有限公司技术创新中心北京100085 北京大学汇丰商学院英国校区华威大学交叉学科研究方法中心英国牛津100871 清华大学建筑学院北京100062 上海工程技术大学管理学院上海021620

2005年是中国承诺碳减排目标的基准年份,因而也是中国城市碳减排战略制定和近中期低碳转型的基准年份和对照年份。中国城市2005年CO_2排放数据的一致性、全面性和精准性对于中国所有城市和每个具体城市的目标考核和评估都有重要意义。... 详细信息

2005年是中国承诺碳减排目标的基准年份,因而也是中国城市碳减排战略制定和近中期低碳转型的基准年份和对照年份。中国城市2005年CO_2排放数据的一致性、全面性和精准性对于中国所有城市和每个具体城市的目标考核和评估都有重要意义。基于中国高空间分辨率网格数据(CHRED 2.0)、城市层面统计数据以及大量现场调研和走访,建立2005年中国城市CO_2排放数据集,包括工业能源排放、工业过程排放、农业排放、服务业排放、城镇生活排放、农村生活排放、交通排放7个部门的直接排放数据和间接排放数据。该数据集的建立汇总了86名研究人员的工作成果,在企业、城市不同行业与部门、城市工业和城市总化石能源等不同层面进行了大量的交叉验证和数据分析,有效保障了数据的精确性和准确性。结果显示,2005年中国城市碳排放呈现出较大的体量差异和空间格局差异。排放前10的城市几乎比排放后10的城市的排放量高出两个数量级。高排放城市基本都是城市群的核心城市。东部城市直接排放占全国直接排放比例最高,达到44.59%,其次是西部城市21.76%,中部城市22.70%,东北城市10.95%。

关键词：城市 CO 2排放数据集中国高空间分辨率网格

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类风湿关节炎患者工作能力障碍的现况调查

中华风湿病学杂志 2012年第2期16卷 77-81页

作者：张晓盈段天娇穆荣楼放李春王秀茹安媛周云杉李晓峰王莉枝王彩虹王永福杨荣王国春卢昕朱平陈丽娜刘金婷靳洪涛刘湘源孙琳魏平王俊洋陈海英崔刘福舒荣刘白鹭张卓莉李光韬李振彬杨静李俊芳贾彬张风肖陶杰梅韩淑玲林金盈韦美秋刘晓敏柯丹胡绍先叶丛杨岫岩李昊黄慈波高明赖蓓李兴福宋立军王轶王晓元苏茵栗占国北京大学人民医院风湿免疫科 100041 北京大学医学部基础医学院清华大学数学系北京大学首钢医院风湿免疫科山西医科大学第二医院风湿免疫科包头医学院第一附属医院风湿免疫科中日友好医院风湿免疫科第四军医大学西京医院风湿免疫科河北医科大学第二医院风湿免疫科北京大学第三医院风湿免疫科河北医科大学第三医院风湿免疫科华北煤炭医学院附属开滦医院风湿免疫科北京大学第一医院风湿免疫科白求恩国际和平医院风湿免疫科河北省邯郸市中心医院风湿免疫科河北省人民医院风湿免疫科广西壮族自治区人民医院风湿免疫科北京顺义区医院风湿免疫科同济医科大学附属同济医院风湿免疫科中山医科大学第一附属医院风湿免疫科北京医院风湿免疫科山东大学齐鲁医院风湿免疫科兰州大学第二医院风湿免疫科

目的了解我国类风湿关节炎（RA）我国患者工作能力障碍的情况，并分析其影响因素。方法采用流行病学现况调查的研究方法，调查全国21家甲等医院风湿病专科737例RA患者，记录患者一般资料和工作能力相关信息，内容包括患者性别、发病年... 详细信息

目的了解我国类风湿关节炎（RA）我国患者工作能力障碍的情况，并分析其影响因素。方法采用流行病学现况调查的研究方法，调查全国21家甲等医院风湿病专科737例RA患者，记录患者一般资料和工作能力相关信息，内容包括患者性别、发病年龄、职业、RA对患者工作的影响及目前经济状况。一般资料采用描述分析，2组均数比较采用t检验，RA患者工作能力障碍的影响因素的相关性分析采用X^2检验及Logistic回归分析。结果本组737例患者中，男女比例为1：4，女性患者发病[（44＋14）岁]早于男性患者[（53±13）岁]。患者因RA出现工作能力障碍占35．2％，其中病退者占8．0％，减少工作量者占24．8％，更换工作者占2．4％，RA患者工作无变化者占33．8％，患病时已退休的患者占20．8％。分析患者工作能力障碍的影响因素，体力劳动者较脑力劳动者出现工作能力障碍更为明显（X^2=20．497，P〈0．01），低学历者（X^2=15．362，P〈0．01）以及健康评定量表（HAQ）评分高的患者（X2=7．511，P=0．004）32作能力障碍发生情况多。多因素Logistic回归分析显示低学历、发病年龄大、体力劳动和HAQ评分高为患者工作能力障碍的正相关因素。收入低的患者（X2=31．882，P〈0．01）以及自费方式支付医疗费用者（X^2=6．903，P=-0．006）也易出现工作能力障碍。结论RA严重影响患者的工作能力，低学历、发病年龄大、体力劳动、HAQ评分高、收入低以及自费方式支付医疗费用者更易出现工作能力障碍。

关键词：关节炎类风湿工作能力评定横断面研究