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深水急流海峡桥梁桩基础群施工关键技术研究

公路 2020年第10期65卷 118-122页

作者：曾宪柳潘文铭中交第二航务工程局有限公司武汉市430012

秀山大桥9~11号墩钻孔桩施工中遇大倾斜裸岩面、大流速、深水海域等复杂环境,通过采用自升降平台船作为起始施工平台,设计双层导向架及可调锁定装置、混凝土锚桩等技术措施,形成稳定的钻孔平台,成功完成了钻孔桩施工作业。该方法安全、... 详细信息

秀山大桥9~11号墩钻孔桩施工中遇大倾斜裸岩面、大流速、深水海域等复杂环境,通过采用自升降平台船作为起始施工平台,设计双层导向架及可调锁定装置、混凝土锚桩等技术措施,形成稳定的钻孔平台,成功完成了钻孔桩施工作业。该方法安全、可靠、经济,可为类似复杂海域的钻孔桩施工提供借鉴。

关键词：桩基础深水急流平台船施工技术

深水急流海峡大跨径曲线变截面预制节段梁悬臂拼装关键技术

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中外公路 2021年第4期41卷 163-167页

作者：曾宪柳中交第二航务工程局第五工程分公司湖北武汉430040

秀山大桥位于深水急流海峡区域,海况十分复杂,副通航孔桥上部结构为(81+4×153+81) m六跨连续-刚构变截面箱梁,桥梁位于超高变坡曲线段,施工采用预制节段悬臂拼装工艺。箱梁悬臂拼装施工悬拼吊机研制、墩旁支架设计、墩顶块安装固结及... 详细信息

秀山大桥位于深水急流海峡区域,海况十分复杂,副通航孔桥上部结构为(81+4×153+81) m六跨连续-刚构变截面箱梁,桥梁位于超高变坡曲线段,施工采用预制节段悬臂拼装工艺。箱梁悬臂拼装施工悬拼吊机研制、墩旁支架设计、墩顶块安装固结及悬拼施工采取了一系列新工艺和创新技术,安全高效完成了施工任务,为复杂海域预制节段梁悬臂拼装施工积累了经验。该文介绍其施工关键技术。

关键词：急流海峡变截面节段梁桥面吊机悬臂拼装

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跨海桥梁超高曲线变截面节段预制关键技术

中国港湾建设 2022年第9期42卷 59-63页

作者：曾宪柳中交第二航务工程局第五工程分公司湖北武汉430040

秀山跨海大桥副通航孔为(81 m+4×153 m+81 m)变截面连续-刚构桥,梁底为1.8次抛物线,桥梁位于半径1600 m超高变坡曲线段,施工采取节段预制悬臂拼装工艺。为确保小半径、超高段变截面梁预制安装精度,项目实施过程中,采用全厂房预制场、... 详细信息

秀山跨海大桥副通航孔为(81 m+4×153 m+81 m)变截面连续-刚构桥,梁底为1.8次抛物线,桥梁位于半径1600 m超高变坡曲线段,施工采取节段预制悬臂拼装工艺。为确保小半径、超高段变截面梁预制安装精度,项目实施过程中,采用全厂房预制场、墩顶块新型预制壳体结构、“双控”测量控制技术,研发了超高扭曲体箱梁自动开合、行走的全自动液压模板系统,新型分离式可调钢筋绑扎台座。钢筋分离式胎架+主胎架创新技术工艺及数字化自动焊接技术,安全高效完成了秀山跨海桥节段梁预制任务,大幅提高了节段梁预制精度。

关键词：桥梁工程超高曲线匹配预制节段梁变截面

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斜拉桥施工挂篮自动化与智能化控制技术应用

中外公路 2021年第1期41卷 122-125页

作者：曾宪柳中交第二航务工程局第五工程分公司湖北武汉430040

传统前支点挂篮主要依靠液压油泵配合千斤顶单点操作,挂篮行走速度慢,挂篮提升、下放、行走操作同步性差,微调纠偏困难、操作繁琐,施工投入人员多,挂篮操作无精密仪器测量,施工精度、智能化程度不高。为解决传统前支点挂篮在施工中的不... 详细信息

传统前支点挂篮主要依靠液压油泵配合千斤顶单点操作,挂篮行走速度慢,挂篮提升、下放、行走操作同步性差,微调纠偏困难、操作繁琐,施工投入人员多,挂篮操作无精密仪器测量,施工精度、智能化程度不高。为解决传统前支点挂篮在施工中的不足,该文通过对前支点挂篮系统进行研发和创新、操作步骤进行简化,以实现前支点挂篮自动化、智能化应用。

关键词：前支点挂篮自动化智能化控制技术

A novel active-passive protection strategy endows carbonyl iron with excellent intelligent anti-corrosion and microwave absorption dual functional characteristics

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Nano Research 2025年第1期18卷 487-500页

作者： Wei Tian Quanyuan Feng Linbo Zhang Yinfan liu xian Jian Longjiang Deng Institute of Microelectronics School of Information Science and TechnologySouthwest Jiaotong UniversityChengdu 611756China National Engineering Researching Centre of Electromagnetic Radiation Control Materials Key Laboratory of Multi-Spectral Absorbing Materials and Structures of Ministry of EducationState Key Laboratory of Electronic Thin Films and Integrated DevicesSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China The Yangtze Delta Region Institute(Huzhou)&School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaHuzhou 313001China

Carbonyl iron absorbers(CI)face significant challenges in practical applications,such as corrosion,interface bonding failure,detachment,and high maintenance ***,we have developed intelligent self-healing technology based on proactive/passive mechanisms via in situ synthesis of self-healing factors(polydopamine/benzotriazole(PDA/BTA))and physical barrier layers(SiO_(2)/1,1,1,3,3,3-hexamethyl disilazane,SiO_(2)/HMDS)to enhance corrosion resistance,while also being compatible with efficient microwave absorption *** unique multiscale structure gives full play to the utilization of the roles of each functional layer,including the intelligent self-healing features of PDA/BTA,physical shielding and spatial confinement characteristics of SiO_(2)/HMDS,and magnetic-dielectric synergistic mechanism resulted from the good impedance matching characteristics,the conduction loss,the interfacial polarization loss and natural *** asfabricated composites achieved an exceptional minimum reflection loss value of-55.4 dB at 10.7 GHz and the effective absorption band of 7.6 ***,it still exhibits obvious self-healing and corrosion resistance characteristics after 360 h corrosion treatment,ascribed to the self-healing mechanism of PDA/BTA and the blocking intervention effect of SiO_(2)/*** work is considered to pave the way for the synthesis of high-performance magnetic absorbers,especially in enhancing their intelligent self-healing ability in corrosive environments.

关键词： microwave absorption intelligent self-healing technology carbonyl iron multiscale structure magneticdielectric synergistic mechanism

Boosting hydrocarbon conversion via Cu-doping induced oxygen vacancies on CeO2 in CO2 electroreduction

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Journal of Energy Chemistry 2025年第1期100卷 66-76页

作者： Lei Xue Tong Shi Chenhui Han Heng Zhang Fenrong liu Haorun Li Yan Wang Xiaojun Gu Shanghong zeng Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials School of Chemistry and Chemical Engineering Inner Mongolia University State Key Laboratory of Coal Conversion Institute of Coal Chemistry Chinese Academy of Sciences Institute of Catalysis Department of Chemistry Zhejiang University National Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization Baotou Research Institute of Rare Earths

Conversion of CO2back to hydrocarbons is the most direct way of closing the“carbon cycle”,and its significance is further enlarged if this process is driven by renewable energies such as ***,precisely controlling the product selectivity towards hydrocarbons against the competitive hydrogen evolution remains challenging,especially for Cu-based ***,we report a novel defect engineering strategy,by which Cu-doping-induced oxygen vacancies on CeO2nanorods were effectively created,with adjustable vacancy/Cu *** resulting optimum catalyst shows up to 79% catalytic current density to hydrocarbons （excluding CO）,with 49% faradaic efficiency to *** and density functional theory unveil that the ratio between oxygen vacancy and Cu affects significantly the formation of*CHO and activation of H2O,which leads to the following deep hydrogenation to *** findings may spur new insights for designing and developing more controllable chemical process relevant to CO2utilization.

关键词： Oxygen vacancy Hydrocarbon production Reaction mechanism

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu liu xiandeng Li Mi Li xian Wu Xiaohui Huang Ajing Xu Yan liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

高寒峡谷地区大跨度混凝土梁斜拉桥主梁施工关键技术

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中国港湾建设 2020年第5期40卷 49-54页

作者：曾宪柳陈诚中交第二航务工程局有限公司湖北武汉430040

荣乌高速公路准格尔黄河特大桥主跨为440 m双塔双索面混凝土斜拉桥。主梁距离地面高度超过120 m,0—1号梁段现浇施工采用在塔上搭设斜支架+抽插压浆式牛腿结构,减少了牛腿与预埋件间的焊接工作量,降低了高大支架安装施工风险。主梁悬浇... 详细信息

荣乌高速公路准格尔黄河特大桥主跨为440 m双塔双索面混凝土斜拉桥。主梁距离地面高度超过120 m,0—1号梁段现浇施工采用在塔上搭设斜支架+抽插压浆式牛腿结构,减少了牛腿与预埋件间的焊接工作量,降低了高大支架安装施工风险。主梁悬浇施工中挂篮自动化控制、斜拉索索力转换及冬季施工采取了一系列新工艺和创新技术,安全高效地完成了主梁施工,为今后类似桥梁施工提供经验和借鉴。

关键词：斜拉桥主梁挂篮悬浇关键技术

Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance

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Neural Regeneration Research 2025年第3期20卷 695-714页

作者： Beibei Wu Yuqing liu Hongli Li Lemei Zhu Lingfeng zeng Zhen Zhang Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina Yangsheng College of Traditional Chinese Medicine Guizhou University of Traditional Chinese MedicineGuiyangGuizhou ProvinceChina Qinhuangdao Shanhaiguan Pharmaceutical Co. LtdQinhuangdaoHebei ProvinceChina National Clinical Research Center for Mental Disorder The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofibrillary *** amyloid plaques are the primary characteristic of Alzheimer's disease in the central nervous system and peripheral organs,targeting amyloid-beta clearance in the central nervous system has shown limited clinical efficacy in Alzheimer's disease *** abnormalities are commonly observed in patients with Alzheimer's *** liver is the primary peripheral organ involved in amyloid-beta metabolism,playing a crucial role in the pathophysiology of Alzheimer's ***,impaired cholesterol metabolism in the liver may exacerbate the development of Alzheimer's *** this review,we explore the underlying causes of Alzheimer's disease and elucidate the role of the liver in amyloid-beta clearance and cholesterol ***,we propose that restoring normal cholesterol metabolism in the liver could represent a promising therapeutic strategy for addressing Alzheimer's disease.

关键词： ABCA1 Alzheimer's disease amyloid-beta apolipoprotein E cholesterol metabolism liver liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid